rac-trans-7-Hydroxy Pramipexole

CAS: 1246818-51-8

Ref. TR-H952145

Product Information

• Name: rac-trans-7-Hydroxy Pramipexole
• Synonyms: 7-Benzothiazolol, 2-amino-4,5,6,7-tetrahydro-6-(propylamino)-, (6R,7S)-rel-, rel-(6R,7S)-2-Amino-4,5,6,7-tetrahydro-6-(propylamino)-7-benzothiazolol, (6SR,7RS)-2-Amino-6-(propylamino)-4,5,6,7-tetrahydrobenzothiazol-7-ol, rac-trans-7-Hydroxypramipexole, (±)-trans-7-Hydroxypramipexole
• CAS: 1246818-51-8

Description

Impurity Pramipexole Related Compound F
Applications Pramipexole derivative used for the preparation of (S)-Pramipexole via resolution of 2,6-diamino-7-hydroxy-4,5,6,7-tetrahydrobenzothiazole derivatives.
References Validation of a column liquid chromatographic method for the analysis of pramipexole and its 5 impurities. Journal of AOAC International (2010), 93(4), 1102-1112. Gegoe, Csaba Lehel; Fejes, Imre; Garaczi, Sandor; Kovacs, Imre; Lukacs, Ferenc; Majercsik, Orsolya; Schneider, Geza. Process for preparation of (S)-pramipexole via resolution of 2,6-diamino-7-hydroxy-4,5,6,7-tetrahydrobenzothiazole derivatives. Eur. Pat. Appl. (2008), 26pp. CODEN: EPXXDW EP 1878731

• Brand: TRC

Chemical properties

• Molecular weight: 227.33
• Formula: C₁₀H₁₇N₃OS
• Color/Form: White to Light Brown Solid
• InChI: InChI=1S/C10H17N3OS/c1-2-5-12-6-3-4-7-9(8(6)14)15-10(11)13-7/h6,8,12,14H,2-5H2,1H3,(H2,11,13)/t6-,8+/m0/s1
• InChI key: InChIKey=UWNDKVURLHPSSG-HTRCEHHLSA-N
• SMILES: CCCN[C@@H]1CCc2nc(N)sc2[C@@H]1O