3’-Hydroxy Repaglinide-d5(Mixture of Diastereomers)

CAS: 1352792-15-4

Ref. TR-H953282

Product Information

• Name: 3’-Hydroxy Repaglinide-d5(Mixture of Diastereomers)
• Synonyms: 2-(Ethoxy-d5)-4-[2-[[1-[2-(3-hydroxy-1-piperidinyl)phenyl]-3-methylbutyl]amino]-2-oxoethyl]benzoic Acid

Description

Applications A labelled metabolite of Repaglinide (R144500(P)), which is a non-sulfonylurea oral hypoglycemic agent and used as an antidiabetic.
References Jarvis, B., et al.: Drugs, 59, 891 (2000); Niemi, M., et al.: Clin. Pharmacol. Ther., 70, 58 (2001); Hatorp, V., et al.: Clin. Pharmacokinet., 41, 471 (2002); Walsky, R., et al.: Drug Metab. Dispos., 33, 413 (2005); Wolffenbuttel, B.H.R., et al.: Eur. J. Clin. Pharmacol., 45, 113 (1993); Ampudia-Blasco, F.J., et al.: Diabetologia, 37, 703 (1994)

• Brand: TRC

Chemical properties

• Molecular weight: 473.62
• Formula: C₂₇H₃₁D₅N₂O₅
• Color/Form: Neat
• InChI: InChI=1S/C9H21NO/c1-3-4-5-6-7-9(10)8(2)11/h8-9,11H,3-7,10H2,1-2H3/t8-,9+/m0/s1
• InChI key: InChIKey=SKURPTBUALFOED-DTWKUNHWSA-N
• SMILES: CCCCCC[C@@H](N)[C@H](C)O