Product Information
Name:16-(R)-Iloprost-d4
Controlled Product
Synonyms:
- [3aS-[2E,3aα,4α(1E,3R*,4S*),5β,6aα]]- 5-[Hexahydro-5-hydroxy-4-(3-hydroxy-4-methyl-1-octen-6-ynyl)-2(1H)-pentalenylidene]-Pentanoic Acid-d4
Brand:TRC
Description:Applications Labeled 16-(R)-Iloprost is the R-isomer of Iloprost (I267300), a synthetic analogue of Prostacyclin (PGI2) used to treat pulmonary arterial hypertension (PAH), scleroderma, Raynaud's phenomenon and ischemia.References Zamudio, T.P.: Arch. Cardiol. Mex., 77, 198 (2007); Lai, Y. et al.: Am. J. Resp. Crit. Care Med., 178, 188 (2008); Scorza, R. et al.: J. Rheutamol., 24, 1944 (1997); Melillo, E. et al.: Int. J. Microcircul. Clin. Exp., 15, 60 (1995);
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Chemical properties
Molecular weight:364.512
Formula:C22D4H28O4
Color/Form:Neat
InChI:InChI=1S/C22H32O4/c1-3-4-7-15(2)20(23)11-10-18-19-13-16(8-5-6-9-22(25)26)12-17(19)14-21(18)24/h8,10-11,15,17-21,23-24H,5-7,9,12-14H2,1-2H3,(H,25,26)/b11-10+,16-8+/t15-,17+,18-,19+,20-,21-/m1/s1/i5D2,6D2
SMILES:[2H]C([2H])(/C=C1\C[C@H]2C[C@@H](O)[C@H](/C=C/[C@@H](O)[C@H](C)CC#CC)[C@H]2C1)C([2H])([2H])CC(=O)O
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