Lovastatin-d9 (Mixture of Diastereomers)

CAS: 75330-75-5

Ref. TR-L472228

Product Information

• Name: Lovastatin-d9 (Mixture of Diastereomers)
• Synonyms: (2S)-2-Methylbutanoic-d9 Acid (1S,3R,7S,8S,8aR)-1,2,3,7,8,8a-Hexahydro-3,7-dimethyl -8-[2-[(2R,4R)-tetrahydro-4-hydroxy-6-oxo-2H-pyran-2-yl]ethyl]-1-naphthalenyl Ester-d9, (+)-Mevinolin-d9, 6a-Methylcompactin-d9, Altocor-d9, Antibiotic MB 530B-d9, L 154803-d9, Lostatin-d9, (1S,3R,7S,8S)-8-{2-[(2R,4R)-4-hydroxy-6-oxotetrahydro-2H-pyran-2-yl]ethyl}-3,7-dimethyl-1,2,3,7,8,8a-hexahydronaphthalen-1-yl (2S)-2-methylbutanoate, (1S,3R,7S,8S,8aR)-8-{2-[(2R,4R)-4-hydroxy-6-oxotetrahydro-2H-pyran-2-yl]ethyl}-3,7-dimethyl-1,2,3,7,8,8a-hexahydronaphthalen-1-yl (2S)-2-methylbutanoate, 6α-Methylcompactin, 8-[2-(4-hydroxy-6-oxotetrahydro-2H-pyran-2-yl)ethyl]-3,7-dimethyl-1,2,3,7,8,8a-hexahydronaphthalen-1-yl 2-methylbutanoate, Altocor, Altoprev, Antibiotic MB 530B, Butanoic acid, 2-methyl-, (1S,3R,7S,8S,8aR)-1,2,3,7,8,8a-hexahydro-3,7-dimethyl-8-[2-[(2R,4R)-tetrahydro-4-hydroxy-6-oxo-2H-pyran-2-yl]ethyl]-1-naphthalenyl ester, (2S)-, Butanoic acid, 2-methyl-, 1,2,3,7,8,8a-hexahydro-3,7-dimethyl-8-[2-(tetrahydro-4-hydroxy-6-oxo-2H-pyran-2-yl)ethyl]-1-naphthalenyl ester, [1S-[1α(R*),3α,7β,8β(2S*,4S*),8aβ]]-, L 154803, Lestric, Lostatin, Lovacard, Lovalip, Lovastatin lactone, Lovastation, Lovastin, Lovex, Mevacor, Mevinacor, Mevinolin, Mevlor, Mk 803, Monacolin K, Monacolin K lactone, Msd 803, Msd803, NSC 633781, Oxy)-1-Naphthaleneheptanoicaciddelta-Lactone, Red Yeast Rice P.E, Sivlor

Description

Applications Lovastatin-d9, is the labeled analogue of Lovastatin (L472225), an antihypercholesterolemic agent. A fungal metabolite, which is a potent inhibitor of HMG-CoA reductase.
References Bilheimer, D.W., et al.: Proc. Nat. Acad. Sci. USA, 80, 4124 (1983),

• Brand: TRC

Chemical properties

• Molecular weight: 413.6
• Formula: C₂₄H₂₇D₉O₅
• Color/Form: Neat
• InChI: InChI=1S/C24H36O5/c1-5-15(3)24(27)29-21-11-14(2)10-17-7-6-16(4)20(23(17)21)9-8-19-12-18(25)13-22(26)28-19/h6-7,10,14-16,18-21,23,25H,5,8-9,11-13H2,1-4H3/t14-,15?,16-,18+,19+,20-,21-,23-/m0/s1/i1D3,3D3,5D2,15D
• InChI key: InChIKey=PCZOHLXUXFIOCF-XCKPEBQVSA-N
• SMILES: [2H]C([2H])([2H])C([2H])([2H])C([2H])(C(=O)O[C@H]1C[C@@H](C)C=C2C=C[C@H](C)[C@H](CC[C@@H]3C[C@@H](O)CC(=O)O3)[C@H]21)C([2H])([2H])[2H]