4-Mercaptomethyl Dipicolinic Acid (>90%)

CAS: 1040401-18-0

Ref. TR-M225380

Product Information

• Name: 4-Mercaptomethyl Dipicolinic Acid (>90%)
• Synonyms: 4-(sulfanylmethyl)pyridine-2,6-dicarboxylic acid

Description

Stability Air Sensitive
Applications A Dipicolinic acid tag for rigid lanthanide tagging of proteins and paramagnetic NMR Spectroscopy. The tag, 4-mercaptomethyl-dipicolinic acid, binds lanthanide ions with nanomolar affinity, is readily attached to proteins via a disulfide bond, and avoids the problems of diastereomer formation associated with most of the conventional lanthanide tags.
References Ikegami, T., et al.: J. Biomol. NMR, 29, 339 (2004), Su, X., et al.: Chembiochem., 7, 1599 (2006), Vlasie, M., et al.: Chem.-Eur. J., 13, 1715 (2007),

• Brand: TRC

Chemical properties

• Molecular weight: 213.21
• Formula: C₈H₇NO₄S
• Purity: >90%
• Color/Form: Neat
• InChI: InChI=1S/C8H7NO4S/c10-7(11)5-1-4(3-14)2-6(9-5)8(12)13/h1-2,14H,3H2,(H,10,11)(H,12,13)
• InChI key: InChIKey=WSVZILXOOFJPGD-UHFFFAOYSA-N
• SMILES: O=C(O)c1cc(CS)cc(C(=O)O)n1