2-[[(3-Methyl-4-nitro-2-pyridinyl)methyl]sulfinyl]-1H-benzimidazole

CAS: 142384-07-4

Ref. TR-M324400

Product Information

• Name: 2-[[(3-Methyl-4-nitro-2-pyridinyl)methyl]sulfinyl]-1H-benzimidazole
• Synonyms: 2-[(3-methyl-4-nitropyridin-2-yl)methylsulfinyl]-1H-benzimidazole
• Brand: TRC
• Description: Applications 2-[[(3-Methyl-4-nitro-2-pyridinyl)methyl]sulfinyl]-1H-benzimidazole is a drug impurity of Lansoprazole, which is a proton pump inhibitor and used to treat stomach and intestinal ulcers.References Figgitt, D., et al.: Drugs, 60, 925 (2000); Katsuki, H., et al.: Eur. J. Clin. Pharmacol., 57, 709 (2001); Barradell, L.B., et al.: Drugs, 44, 225 (1992); Kim, K., et al.: Clin. Pharmacol. Ther., 72, 90 (2002); Niioka, T., et al.: Ther. Drug Monit., 28, 321 (2006)

Chemical properties

• Molecular weight: 316.34
• Formula: C₁₄H₁₂N₄O₃S
• Color/Form: Neat
• InChI: InChI=1S/C14H12N4O3S/c1-9-12(15-7-6-13(9)18(19)20)8-22(21)14-16-10-4-2-3-5-11(10)17-14/h2-7H,8H2,1H3,(H,16,17)
• SMILES: Cc1c([N+](=O)[O-])ccnc1CS(=O)c1nc2ccccc2[nH]1