4-[3-Methoxy-4-[(tetrahydro-2H-pyran-2-yl)oxy]phenyl]-2-butanone

CAS: 223801-42-1

Ref. TR-M349590

Product Information

• Name: 4-[3-Methoxy-4-[(tetrahydro-2H-pyran-2-yl)oxy]phenyl]-2-butanone
• Synonyms: 4-[3-Methoxy-4-(tetrahydropyranyloxy)phenyl]-2-butanone
• Brand: TRC
• Description: Applications 4-[3-Methoxy-4-[(tetrahydro-2H-pyran-2-yl)oxy]phenyl]-2-butanone is an intermediate used in the synthesis of [6]-Shogaol (S357800), which is an aromatic constituent of ginger and the chain-dehydroxylated analog of [6]-Gingerol. [6]-Shogaol has activity very similar to [6]-Gingerol and produced an inhibition of spontaneous motor activity, antipyretic and analgesic effects, and prolonged hexobarbital-induced sleeping time. [6]-Shogaol also has potent antitussive activity and affected the cortical EEG.References Suekawa, M. et al.: J. Pharm-Dyn., 7, 836 (1984); Yoshikawa, M. et al.: Chem. Pharmac. Bull., 40, 2239 (1992)

Chemical properties

• Molecular weight: 278.344
• Formula: C₁₆H₂₂O₄
• Color/Form: Neat
• InChI: InChI=1S/C16H22O4/c1-12(17)6-7-13-8-9-14(15(11-13)18-2)20-16-5-3-4-10-19-16/h8-9,11,16H,3-7,10H2,1-2H3
• InChI key: InChIKey=XYDOIKWKTCWOCM-UHFFFAOYSA-N
• SMILES: COc1cc(CCC(C)=O)ccc1OC1CCCCO1