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Applications (3S,6S,9S)-2-Methyl-9-(1-methylethyl)-13-[2-(1-methylethyl)-4-thiazolyl]-4,8,11-trioxo-3,6-bis(phenylmethyl)-2,7,10,12-tetraazatridecanoic Acid 5-Thiazolymethyl Ester is an intermediate in the synthesis of 4-epi-Ritonavir (Ritonavir EP Impurity O) (R536000), which is an isomer of Ritonavir (R535000), a selective HIV protease inhibitor.
References Daluge, S., et al.: Antimicrob. Agents Chemother., 38, 1590 (1994), Ammaranond, P., et al.: J. Clin. Virol., 26, 153 (2003), Harrigan, P., et al.: J. Infect. Dis., 191, 339 (2005), Miller, J., et al.: Bioorg. Med. Chem. Lett., 16, 1788(2006)
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