4-Methoxy-6-methyl-5,6,7,8-tetrahydro-[1,3]dioxolo[4,5-g]isoquinoline

CAS: 550-10-7

Ref. TR-M543560

Product Information

• Name: 4-Methoxy-6-methyl-5,6,7,8-tetrahydro-[1,3]dioxolo[4,5-g]isoquinoline
• Synonyms: Hydrocotarnine (6CI), 1,3-Dioxolo(4,5-g)isoquinoline, 5,6,7,8-tetrahydro-4-methoxy-6-methyl-, 4-Methoxy-6-Methyl-5,6,7,8-Tetrahydro[1,3]Dioxolo[4,5-G]Isoquinolin-6-Ium Bromide, 4-Methoxy-6-methyl-5,6,7,8-tetrahydro-1,3-dioxolo(4,5-g)isoquinoline, 5,6,7,8-Tetrahydro-4-methoxy-6-methyl-1,3-dioxolo(4,5-g)isoquinoline, 5,6,7,8-Tetrahydro-4-methoxy-6-methyl-1,3-dioxolo(4,5-g)isoquinoline hydrochloride hydrate, Brn 0017283
• CAS: 550-10-7

Description

Applications 4-methoxy-6-methyl-5,6,7,8-tetrahydro-[1,3]dioxolo[4,5-g]isoquinoline (cas# 550-10-7) is used for the antagonism of ABCG4, Lyn kinase, and c-Cbl E3 ligase to increase platelet count as therapy for thrombocytopenia.
References Wang, N., et al.: PCT Int. Appl. 107pp. (2014)

• Brand: TRC

Chemical properties

• Molecular weight: 221.25
• Formula: C₁₂H₁₅NO₃
• Color/Form: Off White Solid
• InChI: InChI=1S/C12H15NO3/c1-13-4-3-8-5-10-12(16-7-15-10)11(14-2)9(8)6-13/h5H,3-4,6-7H2,1-2H3
• InChI key: InChIKey=XXANNZJIZQTCBP-UHFFFAOYSA-N
• SMILES: COc1c2c(cc3c1OCO3)CCN(C)C2