(S,S)-Palonosetron Diethylamide Dihydrochloride
Ref. TR-P165785
| 50mg | Discontinued |
Product Information
Name:
(S,S)-Palonosetron Diethylamide Dihydrochloride
Description:
Applications (S,S)-Palonosetron Diethylamide Dihydrochloride is an intermediate in the synthesis of (S,S)-Palonosetron Acid which itself is an impurity in the synthesis of (S,S) Palonosetron (P165800), serotonin 5-HT3 receptor antagonist used in the prevention and treatment of chemotherapy-induced nausea and vomiting (CINV). Antiemetic.
References Clark, R.D., et al.: J. Med. Chem., 36, 2645 (1993), Wong, E.H.F., et al.: Br. J. Pharmacol., 114, 851 (1995), Grunberg, S.M., et al.: Expert. Opin. Pharmacother., 4, 2297 (2003), Eisenberg, P., et al.: Ann. Oncol., 15, 330 (2004), Siddiqui, M.A.A., et al.: Drugs, 64, 1125 (2004),
Notice:
Our products are intended for lab use only. For any other use, please contact us.
Brand:
TRC
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Chemical properties
Molecular weight:
442.46
Formula:
C23H35N3O•2HCl
Color/Form:
White Solid
InChI:
InChI=1S/C23H35N3O.2ClH/c1-3-26(4-2)23(27)20-10-6-8-18-7-5-9-19(22(18)20)15-24-21-16-25-13-11-17(21)12-14-25;;/h6,8,10,17,19,21,24H,3-5,7,9,11-16H2,1-2H3;2*1H/t19-,21+;;/m1../s1
InChI key:
InChIKey=XSSBNYRDNZEWMT-ZKVWPJASSA-K
SMILES:
[Li]OP(=O)(O)O[C@H]1[C@H](O)[C@@H](OP(=O)(O)O[Li])[C@H](OP(=O)(O)O[Li])[C@@H](O)[C@H]1O
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