Peforelin Trifluoroacetic Acid Salt

CAS: 147859-97-0

Ref. TR-P218335

Product Information

• Name: Peforelin Trifluoroacetic Acid Salt
• Synonyms: 3-L-Tryptophan-5-L-histidine-6-L-aspartic Acid Luteinizing Hormone-releasing Factor I (Petromyzon Marinus) Trifluoroacetic Acid Salt, Luteinizing Hormone-releasing Factor III (Petromyzon Marinus) Trifluoroacetic Acid Salt, Lamprey GnRH III Trifluoroacetic Acid Salt, Lamprey LH-RH III Trifluoroacetic Acid Salt, 5-Oxo-L-prolyl-L-histidyl-L-tryptophyl-L-seryl-L-histidyl-L-α-aspartyl-L-tryptophyl-L-lysyl-L-prolylglycinamide Trifluoroacetic Acid Salt, Peforelin, M.W. 1259.50 C59H74N18O14, Pyr-His-Trp-Ser-His-Asp-Trp-Lys-Pro-Gly-NH2
• CAS: 147859-97-0

Description

Applications Peforelin is Gonadotrophin-releasing Hormone (GnRH), a neuropeptides secreted by the hypothalamus that regulate reproduction in rats. It elicits Follicle-Stimulating Hormone (FSH) releasing activity in swine. Also it is identified in lampreys and possesses a hypothalamic role in reproduction.
References Ferris, J. K., et al.: J. Neuroendocrinol., 27, 772-786 (2015); Bruessow, K., et al.: Theriogenology, 74, 1570-1578 (2010); Sower, S. A., et al.: Gen. Comp. Endocrinol., 170, 276-282 (2011)

• Brand: TRC

Chemical properties

• Molecular weight: 1258.56319
• Formula: C₅₉H₇₄N₁₈O₁₄middot
• Color/Form: White to Off-White Solid
• InChI: InChI=1S/C59H74N18O14.C2HF3O2/c60-16-6-5-12-40(59(91)77-17-7-13-47(77)58(90)66-27-48(61)79)70-52(84)41(18-31-23-64-37-10-3-1-8-35(31)37)72-56(88)45(22-50(81)82)75-55(87)44(21-34-26-63-30-68-34)74-57(89)46(28-78)76-53(85)42(19-32-24-65-38-11-4-2-9-36(32)38)71-54(86)43(20-33-25-62-29-67-33)73-51(83)39-14-15-49(80)69-39;3-2(4,5)1(6)7/h1-4,8-11,23-26,29-30,39-47,64-65,78H,5-7,12-22,27-28,60H2,(H2,61,79)(H,62,67)(H,63,68)(H,66,90)(H,69,80)(H,70,84)(H,71,86)(H,72,88)(H,73,83)(H,74,89)(H,75,87)(H,76,85)(H,81,82);(H,6,7)/t39-,40-,41-,42-,43-,44-,45-,46-,47-;/m0./s1
• InChI key: InChIKey=RTASYRSYWSLWJV-CSYZDTNESA-N
• SMILES: NCCCC[C@H](NC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)[C@H](CC(=O)O)NC(=O)[C@H](Cc1cnc[nH]1)NC(=O)[C@H](CO)NC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)[C@H](Cc1cnc[nH]1)NC(=O)[C@@H]1CCC(=O)N1)C(=O)N1CCC[C@H]1C(=O)NCC(N)=O