rac-Ruxolitinib-d9 (major)
CAS: 2469553-67-9 941688-05-7
Ref. TR-R701998
| 1mg | 211.00 € | ||
| 25mg | 2,598.00 € | ||
| 2500µg | 380.00 € |
Estimated delivery in United States, on Friday 17 May 2024
Product Information
Name:
rac-Ruxolitinib-d9 (major)
Synonyms:
- β-Cyclopentyl-4-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)-1H-pyrazole-1-propanenitrile-d9
- INCB 018424-d9
Description:
Applications Labelled racemic analogue of Ruxolitinib (R702000). Ruxolitinib is a selective Janus tyrosine kinase (JAK1 and JAK2) inhibitor used in the treatment of myeloproliferative neoplasms and psoriasis.
References Shilling, A.D. et al.: Drug Metab. Disp., 38, 2023 (2010); Mesa, R.A.: IDrugs, 13, 394 (2010); Campas-Moya, C.: Drugs Fut., 35, 457 (2010);
Brand:
TRC
Long term storage:
Notes:
Chemical properties
Molecular weight:
315.42
Formula:
C17H9D9N6
Color/Form:
White to Pale Yellow Solid
InChI:
InChI=1S/C17H18N6/c18-7-5-15(12-3-1-2-4-12)23-10-13(9-22-23)16-14-6-8-19-17(14)21-11-20-16/h6,8-12,15H,1-5H2,(H,19,20,21)/i1D2,2D2,3D2,4D2,12D
SMILES:
[2H]C1([2H])C([2H])([2H])C([2H])([2H])C([2H])(C(CC#N)n2cc(-c3ncnc4[nH]ccc34)cn2)C1([2H])[2H]
MDL:
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