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Sematilide Hydrochloride
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Sematilide Hydrochloride

CAS: 101526-62-9

Ref. TR-S255613

Estimated delivery in United States, on Monday 21 Dec 2020

Product Information

Name:
Sematilide Hydrochloride
Synonyms:
  • CK 1752A
  • Sematilide monohydrochloride monohydrate
  • N-(2-Diethylaminoethyl)-4-(methanesulfonamido)benzamide hydrochloride
  • CK-1752A, N-[2-(Diethylamino)ethyl]-4μ-[(methylsulfonyl)amino]benzamide monohydrate monohydrochloride
  • Sematilide monohydrate monohydrochloride
  • N-[2-(diethylamino)ethyl]-4-[(methylsulfonyl)amino]benzamide hydrochloride (1:1)
Description:

Applications Sematilide, also known as CK-1752, is a class III antiarrhythmic. It is a selective delayed rectifier K+ current (IKr) channel blocker. It inhibits rapidly activating Ik in guinea pig atrial myocytes, resulting in the prolongation of action potential duration and refractoriness.
References Tsuchida Ami., et al.: J. Cogn. Neurosci., 21,2263 (2009); Chen, Chih Ming., et al.: Drug Development and Industrial Pharmacy(1990),16(3),379-94.

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Chemical properties

Molecular weight:
313.423646
Formula:
C14H23N3O3S(HCl)
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Hazard Info

UN Number:
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LQ:

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