Synaptamide-d4

CAS: 946524-43-2

Ref. TR-S910002

Product Information

• Name: Synaptamide-d4
• Synonyms: (4Z,7Z,10Z,13Z,16Z,19Z)-N-(2-Hydroxyethyl)-4,7,10,13,16,19-docosahexaenamide-d4, (all-Z)-N-(2-Hydroxyethyl)-4,7,10,13,16,19-docosahexaenamide-d4, (4Z,7Z,10Z,13Z,16Z,19Z)-N-(2-Hydroxyethyl)docosa-4,7,10,13,16,19-hexaenamide-d4
• CAS: 946524-43-2

Description

Applications Synaptamide-d4 is labelled Synaptamide (S910000) which is an endocannabinoid-like derivative of docosahexaenoic acid with cannabinoid-independent function. It has potent synaptogenic activity and structural similarity to anandamide. Synaptamide (S910000) is subjected to hydrolysis by fatty acid amide hydrolase, and can be oxygenated to bioactive metabolites.
References Kim, H., et al.: Prostaglandins Leukot Essent Fatty Acids, 88, 121 (2013); Burstein, S., et al.: Bioorg. Med. Chem., 16, 9644 (2008); Fu, J., et al.: J. Biol. Chem., 282, 1518 (2007)

• Brand: TRC

Chemical properties

• Molecular weight: 375.581
• Formula: C₂₄H₃₃D₄NO₂
• InChI: InChI=1S/C24H37NO2/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18-19-20-21-24(27)25-22-23-26/h3-4,6-7,9-10,12-13,15-16,18-19,26H,2,5,8,11,14,17,20-23H2,1H3,(H,25,27)/b4-3-,7-6-,10-9-,13-12-,16-15-,19-18-/i22D2,23D2
• InChI key: InChIKey=GEEHOLRSGZPBSM-DXYZWJMHSA-N
• SMILES: [2H]C([2H])(O)C([2H])([2H])NC(=O)CC/C=C\C/C=C\C/C=C\C/C=C\C/C=C\C/C=C\CC