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TC ASK 10
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TC ASK 10

CAS: 1005775-55-2 1005775-56-3

Ref. TR-T012000

Estimated delivery in United States, on Monday 14 Dec 2020

Product Information

Name:
TC ASK 10
Synonyms:
  • 4-(1,1-Dimethylethyl)-N-[6-(1H-imidazol-1-yl)imidazo[1,2-a]pyridin-2-yl]-,benzamide Dihydrochloride
  • ‡4-tert-Butyl-N-[6-(1H-imidazol-1-yl)imidazo[1,2-a]pyridin-2-yl]benzamide Dihydrochloride
Description:

Applications TC ASK 10 is a potent ASK1 inhibitor. It displays selectivity for ASK1 over other kinases including ASK2, MEKK1, TAK1, IKK, ERK1, JNK1, p38, GSK-3, PKC and B-raf. It blocks downstream JNK1/p38 phosphorylation in cells.
References Terao, Y., et al.: Bioorg. Med. Chem. Lett., 22, 7326 (2012)

Long term storage:
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Chemical properties

Molecular weight:
432.35
Formula:
C21H23Cl2N5O
Color/Form:
White to Off-White Solid
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Hazard Info

UN Number:
EQ:
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Forbidden to fly:
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Packing Group:
LQ:

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