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Thiazol-5-ylmethyl ((2R,5R)-5-Amino-1,6-diphenylhexan-2-yl)carbamate Hydrochloride
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Thiazol-5-ylmethyl ((2R,5R)-5-Amino-1,6-diphenylhexan-2-yl)carbamate Hydrochloride

CAS: 1247119-33-0

Ref. TR-T344296

50mg
1,059.00 €
Estimated delivery in United States, on Thursday 13 Jun 2024

Product Information

Name:
Thiazol-5-ylmethyl ((2R,5R)-5-Amino-1,6-diphenylhexan-2-yl)carbamate Hydrochloride
Controlled Product
Synonyms:
  • Carbamic acid
  • N-[(1R,4R)-4-amino-5-phenyl-1-(phenylmethyl)pentyl]-
  • 5-thiazolylmethyl ester
  • hydrochloride (1:1)
  • Thiazol-5-ylmethyl N-((1R,4R)-4-Amino-1-benzyl-5-phenylpentyl)carbamate Hydrochloride
  • Carbamic acid, N-[(1R,4R)-4-amino-5-phenyl-1-(phenylmethyl)pentyl]-, 5-thiazolylmethyl ester, hydrochloride (1:1)
  • Thiazol-5-ylmethyl (2R,5R)-5-amino-1,6-diphenylhexan-2-ylcarbaMate hydrochloride
Description:

Applications Thiazol-5-ylmethyl ((2R,5R)-5-Amino-1,6-diphenylhexan-2-yl)carbamate Hydrochloride is an impurity of Cobicistat (C633150), a HIV protease inhibitor that has been coadministered with low-dose ritonavir (R535000) as a pharmacoenhancer.
References Von, H., Exp. Rev. Clin. Pharmacol., 5, 557 (2012); Lepist, E.I., et al.: Antimicrob. Agent. Chemother., 56, 5409 (2012); Orr, S.T.M., et al.: J. Med. Chem., 55, 4896 (2012)

Brand:
TRC
Long term storage:
Notes:

Chemical properties

Molecular weight:
446.0
Formula:
C23H27N3O2S·HCl
InChI:
InChI=1S/C23H27N3O2S.ClH/c24-20(13-18-7-3-1-4-8-18)11-12-21(14-19-9-5-2-6-10-19)26-23(27)28-16-22-15-25-17-29-22, 1H/t20-,21-, /m1./s1, /h1-10,15,17,20-21H,11-14,16,24H2,(H,26,27)
InChI key:
InChIKey=UPZSMWCRMXVNOX-MUCZFFFMSA-N
SMILES:
Cl.N[C@H](CC[C@H](Cc1ccccc1)NC(=O)OCc1cncs1)Cc1ccccc1
MDL:
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EINECS:
Merck:
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Hazard Info

UN Number:
EQ:
Class:
H Statements:
P Statements:
Forbidden to fly:
Hazard Info:
Packing Group:
LQ:

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