Product Information
- N-1-Trityl-deamino-histidine (3-(N-1-Trityl-imidazol-4-yl)propionic acid N-1-Trityl-dihydrourocanic Acid
- 1-(Triphenylmethyl)-1H-imidazole-4-propanoic Acid
- Deamino-His(Trt)-OH
- 3-(1-Tritylimidazol-4-yl)propionic Acid
- 1-(Triphenylmethyl)-1H-imidazole-4-propanoic acid
- 1H-Imidazole-4-propanoic acid, 1-(triphenylmethyl)-
- 3-(1-Trityl-1H-imidazol-4-yl)propanoic acid
- 3-(1-Trityl-1H-imidazol-4-yl)propionic acid
- 3-(1-Tritylimidazol-4-yl)propionic acid
- 3-(N-1-Trityl-Imidazol-4-Yl)Propionic Acid
- See more synonyms
Applications 3-(N-1-Trityl-imidazol-4-yl)propionic Acid is an intermediate used to prepare imidazole-containing tetrahydrobenzodiazepine inhibitors of farnesyltransferase. It is also used in the synthesis of nonracemic arylpiperazinone analogs of the carboxyl-terminal CAAL sequence of protein geranylgeranyltransferase-I (PGGTase-I) as selective inhibitors of PGGTase-I and of protein farnesyltransferase.
References Ding, C., et al.: J. Med. Chem., 42, 5241 (1999); Peng, H., et al.: Org. BIomol. Chem., 4, 1768 (2006)
Chemical properties
Technical inquiry about: TR-T888590 3-(N-1-Trityl-imidazol-4-yl)propionic Acid
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