Vapreotide Acetate

CAS: 116430-60-5

Ref. TR-V097800

Product Information

• Name: Vapreotide Acetate
• Synonyms: D-phenylalanyl-L-cysteinyl-L-tyrosyl-D-tryptophyl-L-lysyl-L-valyl-L-cysteinyl-L-Tryptophanamide Cyclic (2→7)-disulfide 1,2-Dithia-5,8,11,14,17-pentaazacycloeicosane, Cyclic Peptide Deriv., 16: PN: US20020042374 PAGE: 10 Claimed Protein, 20: PN: US6268342 SEQID: 23 Claimed Protein, 3: PN: EP1118336 SEQID: 3 Claimed Protein, BMY 41606, Octastatin, RC 160, RC 160 (protein), Vapreotide acetate, Bmy-41606, Rc-160, Sanvar
• CAS: 116430-60-5

Description

Stability Hygroscopic
Applications Vapreotide is a synthetic somatostatin (S676750) analog predominately used for the treatment of acute variceal bleeding.
References Fortune, B.E., et al.: Expert. Opin. Pharmacother., 10, 14 (2009); Paul, C., et al.: Eng. J. Med., 344, 23 (2001);

• Brand: TRC

Chemical properties

• Molecular weight: 1191.42
• Formula: C₅₉H₇₄N₁₂O₁₁S₂
• Color/Form: White to Off-White Solid
• InChI: InChI=1S/C57H70N12O9S2.C2H4O2/c1-32(2)49-57(78)68-48(55(76)64-44(50(60)71)26-35-28-61-41-16-8-6-14-38(35)41)31-80-79-30-47(67-51(72)40(59)24-33-12-4-3-5-13-33)56(77)65-45(25-34-19-21-37(70)22-20-34)53(74)66-46(27-36-29-62-42-17-9-7-15-39(36)42)54(75)63-43(52(73)69-49)18-10-11-23-58;1-2(3)4/h3-9,12-17,19-22,28-29,32,40,43-49,61-62,70H,10-11,18,23-27,30-31,58-59H2,1-2H3,(H2,60,71)(H,63,75)(H,64,76)(H,65,77)(H,66,74)(H,67,72)(H,68,78)(H,69,73);1H3,(H,3,4)/t40-,43+,44+,45+,46-,47+,48+,49+;/m1./s1
• InChI key: InChIKey=KBIZSMHYSQUHDH-NCACADTJSA-N
• SMILES: CC(=O)O.CC(C)[C@@H]1NC(=O)[C@H](CCCCN)NC(=O)[C@@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2ccc(O)cc2)NC(=O)[C@@H](NC(=O)[C@H](N)Cc2ccccc2)CSSC[C@@H](C(=O)N[C@@H](Cc2c[nH]c3ccccc23)C(N)=O)NC1=O