CAS 130848-06-5

Angelato de decursinol

Descrição:

Angelato de decursinol é um composto químico classificado como um produto natural, especificamente um tipo de derivado de cumarina. É derivado principalmente de plantas da família Apiaceae, particularmente das raízes de Angelica gigas. Este composto é caracterizado por sua estrutura única, que inclui um moiety de decursinol e um grupo éster de angelato. Angelato de decursinol exibe várias atividades biológicas, incluindo propriedades anti-inflamatórias, antioxidantes e potenciais anticancerígenas, tornando-o de interesse na pesquisa farmacológica. Sua solubilidade é geralmente moderada em solventes orgânicos, e pode ter solubilidade limitada em água. A estabilidade do composto pode ser influenciada por fatores ambientais, como luz e temperatura. Assim como muitos produtos naturais, sua extração e purificação podem ser complexas, muitas vezes exigindo métodos específicos para isolá-lo de matrizes vegetais. No geral, Angelato de decursinol representa uma área fascinante de estudo dentro da química de produtos naturais, com aplicações potenciais em medicina e saúde.

Fórmula: C₁₉H₂₀O₅

InChI: InChI=1S/C19H20O5/c1-5-11(2)18(21)23-16-9-13-8-12-6-7-17(20)22-14(12)10-15(13)24-19(16,3)4/h5-8,10,16H,9H2,1-4H3/b11-5-/t16-/m0/s1

Chave InChI: InChIKey=AGABNGOXUSXQDD-XKGFZTIGSA-N

SMILES: CC1(C)OC=2C(C[C@@H]1OC(/C(=C\C)/C)=O)=CC3=C(C2)OC(=O)C=C3

Sinónimos:

• 2-Butenoic acid, 2-methyl-, (7S)-7,8-dihydro-8,8-dimethyl-2-oxo-2H,6H-benzo[1,2-b:5,4-b′]dipyran-7-yl ester, (2Z)-
• 2-Butenoic acid, 2-methyl-, 7,8-dihydro-8,8-dimethyl-2-oxo-2H,6H-benzo[1,2-b:5,4-b′]dipyran-7-yl ester, [S-(Z)]-
• 2-Butenoicacid, 2-methyl-, 7,8-dihydro-8,8-dimethyl-2-oxo-2H,6H-benzo[1,2-b:5,4-b']dipyran-7-ylester, [S-(Z)]-
• 2H,6H-Benzo[1,2-b:5,4-b']dipyran, 2-butenoic acid deriv.
• Acutilobin
• Decursinol angelate

Decursinol angelate

CAS: 130848-06-5

Fórmula: C₁₉H₂₀O₅

Pureza: 98%

Cor e Forma: Solid

Peso molecular: 328.3591

Ref: IN-DA009B3Z

(S)-8,8-Dimethyl-2-Oxo-7,8-Dihydro-2H,6H-Pyrano[3,2-G]Chromen-7-Yl (Z)-2-Methylbut-2-Enoate

CAS: 130848-06-5

(S)-8,8-Dimethyl-2-Oxo-7,8-Dihydro-2H,6H-Pyrano[3,2-G]Chromen-7-Yl (Z)-2-Methylbut-2-Enoate

Pureza: 98%

Peso molecular: 328.36g/mol

Ref: 54-OR1023111

Decursinol angelate

CAS: 130848-06-5

Decursinol angelate

Pureza: ≥98%

Peso molecular: 328.36g/mol

Ref: 54-BUP10926

Decursinol angelate

CAS: 130848-06-5

Fórmula: C₁₉H₂₀O₅

Peso molecular: 328.36

Ref: 7W-GY9577

Decursinol angelate

CAS: 130848-06-5

Decursinol angelate has anti-tumor, anti-inflammatory, anti-oxidant, and hepatoprotective activities, it inhibits VEGF-induced angiogenesis via suppression of the VEGFR-2-signaling pathway; it also suppresses invasion and inflammatory activation of cancer cells through modulation of PI3K/AKT, ERK and NF-kappaB, its anti-inflammatory activity may contribute to its anti-cancer activity.Decursinol angelate has protective effects against amyloid β-protein-induced oxidative stress in the PC12 cell line. It improves wound healing by upregulating the expression of genes encoding extracellular matrix remodeling proteins, inflammatory cytokines, and growth factors. Decursinol angelate has in vitro and in vivo antifungal activity against Magnaporthe oryzae, the causal agent of rice blast.

Fórmula: C₁₉H₂₀O₅

Pureza: 95%~99%

Peso molecular: 328.364

Ref: BP-BP1812

Decursinol angelate

CAS: 130848-06-5

Decursinol angelate is anti-tumor, anti-inflammatory, anti-oxidant, hepatoprotective, and inhibits VEGF and cancer cell invasion.

Fórmula: C₁₉H₂₀O₅

Pureza: 99.93%

Cor e Forma: Solid

Peso molecular: 328.36

Ref: TM-TN1557

Decursinol angelate

CAS: 130848-06-5

Lactone

Fórmula: C₁₉H₂₀O₅

Pureza: ≥ 90.0 % (HPLC)

Peso molecular: 328.36

Ref: 5G-84209

Decursinol angelate

CAS: 130848-06-5

Decursinol angelate is a bioactive compound, which is derived from the roots of plants such as Angelica gigas, a species commonly used in traditional Asian medicine. This compound is a coumarin derivative, known for its potential pharmacological properties. Decursinol angelate’s mode of action involves the modulation of inflammatory pathways, particularly through the inhibition of key enzymes and cytokines involved in inflammatory responses, such as COX-2 and TNF-alpha. This modulation leads to a reduction in the synthesis of pro-inflammatory mediators, which can be beneficial in managing inflammation-related conditions.

Fórmula: C₁₉H₂₀O₅

Pureza: Min. 95%

Cor e Forma: Powder

Peso molecular: 328.36 g/mol

Ref: 3D-FFA84806

Decursinol angelate - Bio-X ™

CAS: 130848-06-5

This product is part of our Bio-X ™ Range. These products are aimed at life science researchers who need high quality ready-to-use products for assay development, screening or other R&D work. With a solubility datasheet and convenient vials, all of our Bio-X ™ products are in stock across our global warehouses for rapid delivery and ease of use.

Fórmula: C₁₉H₂₀O₅

Pureza: Min. 95%

Cor e Forma: Powder

Peso molecular: 328.36 g/mol

Ref: 3D-BD300081