CAS 2301866-59-9

DO-264

CAS: 2301866-59-9

DO-264

Fórmula: C₂₃H₂₀Cl₂F₃N₅O₂S

Pureza: ≥95%

Peso molecular: 558.4

Ref: 54-BUP00503

DO-264

CAS: 2301866-59-9

Fórmula: C₂₃H₂₀Cl₂F₃N₅O₂S

Pureza: 98%

Peso molecular: 558.4034

Ref: IN-DA01FS3T

DO-264

CAS: 2301866-59-9

1-(1-(3-Chloro-4-(2-chloro-4-(trifluoromethoxy)phenoxy)pyridin-2-yl)piperidin-4-yl)-3-(pyridin-3-yl)thiourea

Fórmula: C₂₃H₂₀Cl₂F₃N₅O₂S

Pureza: 98%

Peso molecular: 558.4

Ref: IN-DG00976995

DO 264

CAS: 2301866-59-9

Inhibits lysophosphatidylserine hydrolysis by the integral membrane serine hydrolase ABHD12 (IC50 = 1.3 µM). Raised levels of lysophosphatidylserine were observed in mouse brain in vivo and in primary human macrophages. DO 264 had proinflammatory effects, following infection with lymphocytic choriomeningitis virus (LCV) clone 13 in mice, resulting in severe inflammatory lung damage.

Fórmula: C₂₃H₂₀Cl₂F₃N₅O₂S

Pureza: Min. 95%

Cor e Forma: White/Off-White Solid

Peso molecular: 558.4 g/mol

Ref: 3D-BD167529

DO-264

CAS: 2301866-59-9

DO-264 is an inhibitor of autohydrolase structural domain 12 (ABHD12) and an inhibitor of cellular LysoPS degradation that enhances LPS-induced phagocytosis.

Fórmula: C₂₃H₂₀Cl₂F₃N₅O₂S

Pureza: 97.72% - 99.95%

Cor e Forma: White Solid

Peso molecular: 558.4

Ref: TM-T11069