Apoptose
Os inibidores da apoptose são compostos que previnem ou retardam o processo de morte celular programada, conhecido como apoptose. Esses inibidores são vitais no estudo dos mecanismos de sobrevivência celular e são usados para investigar doenças onde a apoptose é desregulada, como câncer, distúrbios neurodegenerativos e doenças autoimunes. Ao modular a apoptose, esses inibidores podem ajudar no desenvolvimento de terapias destinadas a controlar a morte celular. Na CymitQuimica, oferecemos uma ampla seleção de inibidores da apoptose de alta qualidade para apoiar sua pesquisa em biologia celular, oncologia e áreas relacionadas.
Subcategorias de "Apoptose"
- ASK(6 produtos)
- BCL(11 produtos)
- Caspase(125 produtos)
- FOXO1(3 produtos)
- IAP(66 produtos)
- Mdm2(12 produtos)
- PD-1/PD-L1(125 produtos)
- PDK(9 produtos)
- PERK(25 produtos)
- Serina/treonina quinase(15 produtos)
- Survivina(13 produtos)
- TNF(92 produtos)
- c-RET(51 produtos)
- p53(62 produtos)
Exibir 6 mais subcategorias
Foram encontrados 5592 produtos de "Apoptose"
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Cidofovir
CAS:<p>Cidofovir ((S)-HPMPC) 通过特异性抑制病毒 DNA 合成来抑制病毒复制。</p>Fórmula:C8H14N3O6PPureza:99.24% - 99.76%Cor e Forma:Fluffy White PowderPeso molecular:279.19Galanthamine
CAS:<p>Galanthamine (Galantamine) is an acetylcholinesterase (AChE)inhibitor(IC50 : 500 nM), can reduce brain damage induced by hypoxia-ischemia.</p>Fórmula:C17H21NO3Pureza:98.03% - 99.87%Cor e Forma:Off-White SolidPeso molecular:287.35Raddeanin A
CAS:<p>Raddeanin A is a natural triterpenoid saponin from Cyperus japonicus that inhibits histone deacetylase.Cost-effective and quality-assured.</p>Fórmula:C47H76O16Pureza:98% - 99.94%Cor e Forma:SolidPeso molecular:897.1Nirogacestat
CAS:<p>Nirogacestat (PF 03084014) is a specific γ-secretase inhibitor (IC50: 6.2 nM, in a cell-free assay).</p>Fórmula:C27H41F2N5OPureza:97.98% - 99.63%Cor e Forma:SolidPeso molecular:489.64Mivebresib
CAS:<p>Mivebresib (ABBV-075) is a potent BET inhibitor with antitumor effects, disrupting gene expression and MYC, TMPRSS2-ETS proteins.</p>Fórmula:C22H19F2N3O4SPureza:98.74% - 99.32%Cor e Forma:SolidPeso molecular:459.47PFK-158
CAS:<p>PFK-158 is an effective and specific inhibitor PFKFB3.</p>Fórmula:C18H11F3N2OPureza:95.49% - 99.16%Cor e Forma:SolidPeso molecular:328.29NVP-TAE 684
CAS:<p>NVP-TAE 684 (TAE684) is a excellently effective and specific ALK inhibitor(IC50=3 nM).</p>Fórmula:C30H40ClN7O3SPureza:98% - 99.82%Cor e Forma:SolidPeso molecular:614.2Oxychlororaphine
CAS:<p>Oxychlororaphine (phenazine-1-carboxamide) inhibits strongly the growth of Streptomyces sp. 441.</p>Fórmula:C13H9N3OPureza:98.3%Cor e Forma:Green-Yellow SolidPeso molecular:223.23L-Buthionine-(S,R)-sulfoximine hydrochloride
<p>L-Buthionine-(S,R)-sulfoximine hydrochloride is a fast, irreversible γ-GCS inhibitor that depletes glutathione. IC50: 1.9-29 μM in various tumors.</p>Fórmula:C8H19ClN2O3SCor e Forma:SolidPeso molecular:258.77Panobinostat lactate
CAS:<p>Panobinostat lactate: potent, non-selective, oral HDAC inhibitor; treats refractory multiple myeloma.</p>Fórmula:C24H29N3O5Cor e Forma:SolidPeso molecular:439.512S-99
CAS:<p>S-99 is a high purity chemical that targets ASK and is important for Immunology, Inflammation, Cancer research.</p>Fórmula:C16H15F3N6OPureza:99.61%Cor e Forma:SolidPeso molecular:364.33Pitavastatin sodium
CAS:<p>Pitavastatin sodium inhibits HMG-CoA reductase, enhances LDL-C receptors, and has various protective effects.</p>Fórmula:C25H23FNNaO4Cor e Forma:SolidPeso molecular:443.45Moexipril
CAS:<p>Moexipril is an oral ACE inhibitor, lipid-soluble, targets plasma/tissue ACE, and is used for cardiovascular research.</p>Fórmula:C27H34N2O7Cor e Forma:SolidPeso molecular:498.57BIX01294 (hydrochloride hydrate)
CAS:<p>BIX01294 inhibits G9a HMTase (IC50=1.7μM), less effective on GLP, and aids in induced pluripotent stem cell generation.</p>Fórmula:C28H43Cl3N6O3Cor e Forma:SolidPeso molecular:618.04PF-573228
CAS:<p>PF-573228 is an ATP-competitive FAK inhibitor. In a cell-free assay, the IC50 of FAK is 4 nM.</p>Fórmula:C22H20F3N5O3SPureza:96.58% - 99.51%Cor e Forma:SolidPeso molecular:491.49AX-024
CAS:<p>AX-024 is an oral inhibitor of TCR-Nck with a 1 nM IC50, targeting SH3 domains, has low toxicity, is potent and selective, and reduces key cytokines.</p>Fórmula:C21H22FNO2Cor e Forma:SolidPeso molecular:339.4TREM2-IN-1
CAS:<p>TREM2-IN-1 (OPA) is a platinum-based TREM2 inhibitor with anti-cancer and anti-tumor activity, inhibiting the immune-regulatory activity of TREM2 on macrophages</p>Fórmula:C46H68N2O20PtPureza:98.56%Cor e Forma:SolidPeso molecular:1164.12MPP dihydrochloride (289726-02-9 Free base)
CAS:<p>MPP dihydrochloride is a highly selective antagonist of estrogen receptor alpha (ERα).</p>Fórmula:C29H33Cl2N3O3Cor e Forma:SolidPeso molecular:542.5Ac-DEVD-pNA
CAS:<p>Ac-DEVD-pNA is the preferred peptidic substrate for caspase-3.</p>Fórmula:C26H34N6O13Pureza:>99.99%Cor e Forma:WhitePeso molecular:638.58Pioglitazone potassium
CAS:<p>Pioglitazone potassium is an oral PPARγ agonist with EC50 of 0.93 μM (human) and 0.99 μM (mouse), used in diabetes research.</p>Fórmula:C19H19KN2O3SCor e Forma:SolidPeso molecular:394.53Alantolactone
CAS:<p>Alantolactone is a selective inhibitor of STAT3 that induces cancer-associated apoptosis and has antitumor activity.Cost-effective and quality-assured.</p>Fórmula:C15H20O2Pureza:99.02% - 99.66%Cor e Forma:Crystalline PowderPeso molecular:232.32Nobiletin
CAS:<p>Nobiletin: a citrus-derived flavone with anti-inflammatory and anti-cancer properties; water-insoluble, very weak acid.</p>Fórmula:C21H22O8Pureza:98.65% - 99.76%Cor e Forma:SolidPeso molecular:402.39PD173955
CAS:<p>PD173955 is src family-selective tyrosine kinase inhibitor with IC50 of ~22 nM for Src, Yes and Abl kinase; less potent for FGFRα and no activity on InsR and</p>Fórmula:C21H16Cl2N4OSPureza:98.52% - 98.99%Cor e Forma:SolidPeso molecular:443.35RGX-202
CAS:<p>RGX-202 (β-GPA) is an orally active inhibitor of the SLC6A8 transport protein. RGX-202 is a creatine analog that alters skeletal muscle energy expenditure.</p>Fórmula:C4H9N3O2Pureza:99.67% - 99.8%Cor e Forma:SolidPeso molecular:131.13Licochalcone D
CAS:<p>Licochalcone D may treat melanoma and heart injury, halt cell spread, and reduce inflammation and allergies.</p>Fórmula:C21H22O5Pureza:99.03% - 99.9%Cor e Forma:SolidPeso molecular:354.4(-)-Alkannin
CAS:<p>(-)-Alkannin (Shikonin) is a natural red naphthoquinone pigment, has antimicrobial, anti-tumor, and anti-inflammatory effects.</p>Fórmula:C16H16O5Pureza:98.18% - 98.8%Cor e Forma:White Or Slightly Yellow Crystalline Powder SolidPeso molecular:288.3C646
CAS:<p>C646, a histone acetyltransferase inhibitor, inhibits p300 (Ki: 400 nM, in a cell-free assay).</p>Fórmula:C24H19N3O6Pureza:98% - 99.21%Cor e Forma:SolidPeso molecular:445.42Flurbiprofen Axetil
CAS:<p>Flurbiprofen Axetil (Lipfen) is an anti-inflammatory used as an analgesic.</p>Fórmula:C19H19FO4Pureza:97.58% - 98%Cor e Forma:SolidPeso molecular:330.35Radotinib
CAS:<p>Radotinib (IY-5511), and sometimes referred to by its investigational name IY5511, is a drug for the treatment of different types of Y, most notably</p>Fórmula:C27H21F3N8OPureza:99.13% - 99.97%Cor e Forma:SolidPeso molecular:530.5Neobavaisoflavone
CAS:<p>Neobavaisoflavone: DNA polymerase inhibitor, potential for treating bone loss, anti-inflammatory, reduces ROS, RNS, cytokines in macrophages.</p>Fórmula:C20H18O4Pureza:99.31% - 99.87%Cor e Forma:SolidPeso molecular:322.35EI1
CAS:<p>EI1 (Ezh2 inhibitor) is a potent and selective EZH2 inhibitor with IC50 of 15 nM and 13 nM for EZH2 (WT) and EZH2 (Y641F), respectively.</p>Fórmula:C23H26N4O2Pureza:99.93%Cor e Forma:SolidPeso molecular:390.48pimpinellin
CAS:<p>Pimpinellin is a natural product that acts as antagonist of proteins with GABA receptor activity.</p>Fórmula:C13H10O5Pureza:99.85% - ≥95%Cor e Forma:SolidPeso molecular:246.22DAPT
CAS:<p>DAPT (LY-374973) is a γ-secretase inhibitor that inhibits total Aβ and Aβ42 (IC50=115/200 nM) and is orally active.</p>Fórmula:C23H26F2N2O4Pureza:98.06% - 99.81%Cor e Forma:White SolidPeso molecular:432.46Ibandronate sodium monohydrate
CAS:<p>Ibandronate sodium monohydrate (BM-210955) is a highly potent nitrogen-containing bisphosphonate used for the treatment of osteoporosis.</p>Fórmula:C9H24NNaO8P2Pureza:99.62%Cor e Forma:White Crystalline PowderPeso molecular:359.23Medicarpin
CAS:<p>Medicarpin, an ER agonist, stimulates osteoblasts, enhances peak bone mass, has no uterine effects, and is orally bioavailable.</p>Fórmula:C16H14O4Pureza:99.32% - 99.86%Cor e Forma:SolidPeso molecular:270.28Danshensu
CAS:<p>Danshensu (Dan shen suan A) is an active ingredient of Salvia miltiorrhiza with wide cardiovascular benefit.</p>Fórmula:C9H10O5Pureza:98.4% - 99.74%Cor e Forma:SolidPeso molecular:198.17MDK83190
CAS:<p>MDK83190 (Apoptosis Activator 2) is a potent apoptosis activator, induceing caspase-3 activation, PARP cleavage, and DNA fragmentation .</p>Fórmula:C15H9Cl2NO2Pureza:97.40% - 98%Cor e Forma:Orange SolidPeso molecular:306.14Salubrinal
CAS:<p>Salubrinal, a phosphatases (PP1) inhibitor(IC50=1.7 μM), exhibits function on the eukaryotic translation initiation factor 2 subunit (eIF2α).</p>Fórmula:C21H17Cl3N4OSPureza:97.25% - >99.99%Cor e Forma:SolidPeso molecular:479.81Vesatolimod
CAS:<p>Vesatolimod (GS-9620) is an effective and specific orally active agonist of Toll-like receptor 7.</p>Fórmula:C22H30N6O2Pureza:97.46% - 99.03%Cor e Forma:SolidPeso molecular:410.51IC261
CAS:<p>IC261 (SU-5607) is a novel inhibitor of CK1, triggers the mitotic checkpoint control. The IC50 of IC261 for CK1 was 16 μM and for Cdk5 is 4.5 mM.</p>Fórmula:C18H17NO4Pureza:99.45% - 99.91%Cor e Forma:SolidPeso molecular:311.33Glycochenodeoxycholic Acid
CAS:<p>Glycochenodeoxycholic Acid (Lithocholylglycine) is a glycine conjugate of lithocholic acid, a bile acid.</p>Fórmula:C26H43NO5Pureza:97% - 99.97%Cor e Forma:SolidPeso molecular:449.62Epoxomicin
CAS:<p>Epoxomicin, a selective proteasome inhibitor, chiefly blocks CH-L activity, mildly affecting T-L and PGPH at lower rates.</p>Fórmula:C28H50N4O7Pureza:98.65% - 98.86%Cor e Forma:White To Off-White SolidPeso molecular:554.72Flavokawain B
CAS:<p>Flavokawain B inhibits NO and PGE2, causes oxidative stress, and induces apoptosis, with potential for treating prostate cancer.</p>Fórmula:C17H16O4Pureza:99.97% - >99.99%Cor e Forma:SolidPeso molecular:284.31Tandutinib
CAS:<p>Tandutinib (CT53518) (MLN518, CT53518), an effective FLT3 antagonist (IC50: 0.22 μM), can also inhibit c-Kit and PDGFR, 15-20 fold higher potency for FLT3</p>Fórmula:C31H42N6O4Pureza:99.45% - ≥98%Cor e Forma:White SolidPeso molecular:562.7K-Ras(G12C) inhibitor 12
CAS:<p>K-Ras(G12C) inhibitor 12 is an allosteric inhibitor of oncogenic K-Ras(G12C).</p>Fórmula:C15H17ClIN3O3Pureza:97.16%Cor e Forma:SolidPeso molecular:449.67Eltrombopag
CAS:<p>Eltrombopag (SB-497115-GR), an orally active thrombopoietin receptor agonist with megakaryopoiesis stimulating activity, binds to and stimulates the platelet</p>Fórmula:C25H22N4O4Pureza:99.27%Cor e Forma:Orange To Red SolidPeso molecular:442.47SRS11-92
CAS:<p>SRS11-92 (AA9) is a ferroptosis inhibitor and a derivative of ferrostatin-1</p>Fórmula:C22H28N2O2Pureza:98.58%Cor e Forma:SolidPeso molecular:352.47Tubeimoside I
CAS:<p>Tubeimoside I (Tubeimoside-1)(Lobatoside-H) is an extract from Chinese herbal medicine Bolbostemma paniculatum (MAXIM).</p>Fórmula:C63H98O29Pureza:98.89% - 99.94%Cor e Forma:SolidPeso molecular:1319.43NVP 231
CAS:<p>NVP-231 is a potent, specific and reversible CerK inhibitor(IC50=12±2 nM) that competitively inhibits ceramide binding to CerK.</p>Fórmula:C25H25N3O2SPureza:99.16% - ≥95%Cor e Forma:SolidPeso molecular:431.55Rimiducid
CAS:<p>Rimiducid, a tacrolimus analogue, dimerizes FKBP domains to activate Caspase 9 and induce apoptosis; binds FKBP12 weakly.</p>Fórmula:C78H98N4O20Pureza:99.54%Cor e Forma:SolidPeso molecular:1411.63NSC 15364
CAS:<p>NSC 15364 (1,3-Bis(4-aminophenyl)urea) can be used for screening of ALR inhibitors by detection of hydrogen peroxide production Measured in Biochemical System.</p>Fórmula:C13H14N4OPureza:98.67%Cor e Forma:SolidPeso molecular:242.28Afatinib
CAS:<p>Afatinib (BIBW 2992) is an irreversible and orally EGFR family inhibitor that inhibits EGFR and HER2. Afatinib has antitumor activity. Cost effective and quality assured.</p>Fórmula:C24H25ClFN5O3Pureza:98.56% - 99.9%Cor e Forma:Off-White SolidPeso molecular:485.94Hypericin
CAS:<p>Hypericin (Cyclosan) is a natural anthraquinone compound. Hypericin exhibits antimicrobial, antiviral, antitumor, and antidepressant effects. Cost-effective and quality-assured.</p>Fórmula:C30H16O8Pureza:99.05% - ≥98%Cor e Forma:Red-Coloured Anthraquinone-DerivativePeso molecular:504.44Deoxypodophyllotoxin
CAS:<p>Deoxypodophyllotoxin is cytotoxic, antineoplastic, anti-tumor, anti-angiogenic, antiviral, and anti-inflammatory.</p>Fórmula:C22H22O7Pureza:99.65% - 99.84%Cor e Forma:SolidPeso molecular:398.41Cysteamine hydrochloride
CAS:<p>Cysteamine hydrochloride (Thioethanolamine Hydrochloride) is an agent for the treatment of nephropathic cystinosis and an antioxidant.</p>Fórmula:C2H7NS·HClPureza:99.34% - 99.87%Cor e Forma:White Crystalline Powder With A Strong And Disagreeable SmellPeso molecular:113.61iCRT3
CAS:<p>iCRT3 is a Wnt and β-catenin-responsive transcription inhibitor.</p>Fórmula:C23H26N2O2SPureza:98.32% - 98.47%Cor e Forma:SolidPeso molecular:394.53Alvespimycin hydrochloride
CAS:<p>Alvespimycin hydrochloride (BMS 826476) is a potent HSP90 inhibitor with IC50 of 62 nM. Phase 2.</p>Fórmula:C32H48N4O8·HClPureza:99.94%Cor e Forma:SolidPeso molecular:653.21Torin 2
CAS:<p>Torin 2: mTOR inhibitor, IC50=0.25 nM, 800x more selective than PI3K, with EC50=28/35/118 nM for ATM/ATR/DNA-PK.</p>Fórmula:C24H15F3N4OPureza:98.31% - 99.32%Cor e Forma:SolidPeso molecular:432.4NQDI-1
CAS:<p>NQDI-1 (NQDI 1) is a selective inhibitor of apoptosis signal-regulating kinase 1 (ASK1, MAP3K5) (IC50/Ki: 3 μM/500 nM).</p>Fórmula:C19H13NO4Pureza:97.1% - 98.10%Cor e Forma:SolidPeso molecular:319.31TM5441
CAS:<p>TM5441 is an orally bioavailable fibrinogen activator inhibitor-1 inhibitor that inhibits several cancer cell lines with IC50 values ranging from 13.9 to 51.1 μM.Cost-effective and quality-assured.Cost-effective and quality-assured.</p>Fórmula:C21H17ClN2O6Pureza:97.62% - 99.09%Cor e Forma:SolidPeso molecular:428.82BTdCPU
CAS:<p>BTdCPU is a potent activator of heme-regulated eIF2α kinase (HRI) . BTdCPU promotes eIF2α phosphorylation and induced apoptosis in resistant cell.</p>Fórmula:C13H8Cl2N4OSPureza:98.94% - 99.59%Cor e Forma:SolidPeso molecular:339.2Angiotensin II human
CAS:<p>Angiotensin II acts on AT1/AT2 receptors, 30% similar seven-transmembrane glycoproteins, converted from Ang I by ACE.</p>Fórmula:C50H71N13O12Pureza:95% - >99.99%Cor e Forma:SolidPeso molecular:1046.18Levomenol
CAS:<p>Levomenol, or (-)-α-Bisabolol, is a sesquiterpene in aromatic plant oils with antioxidant, anti-inflammatory, and anti-apoptotic properties.</p>Fórmula:C15H26OPureza:96.01%Cor e Forma:Clear To Yellowish LiquidPeso molecular:222.37EF24
CAS:<p>EF24 treatment boosts caspase 3/9 activity, hinders MEK1/ERK phosphorylation, and exhibits strong anti-tumor effects in OSCC by deactivating MAPK/ERK.</p>Fórmula:C19H15F2NOPureza:99.71%Cor e Forma:SolidPeso molecular:311.33Deferitrin
CAS:<p>Deferitrin (GT-56-252) is an iron chelator. It potentially for the treatment of thalassemia and iron overload.</p>Fórmula:C11H11NO4SPureza:98.71%Cor e Forma:SolidPeso molecular:253.27TASIN-1
CAS:<p>TASIN-1 is a small molecule inhibitor of mutant adenomatous polyposis coli (APC).</p>Fórmula:C18H28N2O3SPureza:99.86%Cor e Forma:SolidPeso molecular:352.49Glafenine Hydrochloride
CAS:<p>Glafenine Hydrochloride is an anti-inflammatory agent.</p>Fórmula:C19H17ClN2O4·HClPureza:98.89%Cor e Forma:SolidPeso molecular:409.26Parcetasal
CAS:<p>Parcetasal (MR-897) is a non-steroidal anti-inflammatory agent that can be used in pain relief studies.</p>Fórmula:C17H15NO5Pureza:99.07%Cor e Forma:SolidPeso molecular:313.3L524-0366
CAS:<p>L524-0366 ([1-(3-chlorophenyl)triazol-4-yl]-thiomorpholino-methanone) is a TWEAK-Fn14 signaling cascade inhibitor.</p>Fórmula:C13H13ClN4OSPureza:98.6% - 99.13%Cor e Forma:SolidPeso molecular:308.79Epibrassinolide
CAS:<p>Epibrassinolide (BP55) (EBR) is a biologically active compound of the brassinosteroids, is a natural brassinosteroid (BR) derivative, is a plant regulator with</p>Fórmula:C28H48O6Pureza:97.57% - 98.11%Cor e Forma:SolidPeso molecular:480.68Tenilsetam
CAS:<p>Tenilsetam: an endonuclease, nootropic, AGE inhibitor potential for Alzheimer's.</p>Fórmula:C8H10N2OSPureza:99.52%Cor e Forma:SolidPeso molecular:182.24Benzarone
CAS:<p>Benzarone (Benzarona) is a potent inhibitor of human uric acid transporter 1 (URAT1, IC50 = 2.8 μM in oocyte). Benzarone lowers the level of uric acid serum.</p>Fórmula:C17H14O3Pureza:99.77%Cor e Forma:SolidPeso molecular:266.29Isobutylparaben
CAS:<p>Isobutylparaben is a preservative and preservative insecticide.</p>Fórmula:C11H14O3Pureza:99.36%Cor e Forma:White CreamPeso molecular:194.23Quinocetone
CAS:<p>Quinocetone is an animal growth promoter and potential anti-tumor activity.</p>Fórmula:C18H14N2O3Pureza:98.06%Cor e Forma:SolidPeso molecular:306.32RO8994
CAS:<p>RO8994: potent MDM2 spiroindolinone inhibitor, IC50: 20 nM (proliferation), 5 nM (binding).</p>Fórmula:C31H31Cl2FN4O4Pureza:99.31% - 99.44%Cor e Forma:SolidPeso molecular:613.51NSC 3852
CAS:<p>NSC 3852 is a potent inhibitor of histone deacetylase.</p>Fórmula:C9H6N2O2Pureza:99.64%Cor e Forma:Slightly Yellow To Yellow-Green PowderPeso molecular:174.16NS-3-008 hydrochloride
CAS:<p>NS-3-008 hydrochloride (NS-3-008 HCl) is a transcriptional G0/G1 switch 2 (G0s2) inhibitor( IC50 of 2.25 μM).</p>Fórmula:C14H24ClN3Pureza:99.56%Cor e Forma:SolidPeso molecular:269.81Rhapontin
CAS:<p>Rhapontin may reduce liver fat and better blood sugar/lipids, showing potential for treating type 2 diabetes.</p>Fórmula:C21H24O9Pureza:99% - 99.91%Cor e Forma:Light YellowPeso molecular:420.41Licochalcone B
CAS:<p>Licochalcone B inhibits human bladder cancer cells, reduces inflammation by NO, TNFalpha, and MCP-1, and a derivative protects against endotoxin shock.</p>Fórmula:C16H14O5Pureza:99.33% - 99.93%Cor e Forma:SolidPeso molecular:286.28Trametinib
CAS:<p>Trametinib (GSK1120212), an ATP-noncompetitive MEK 1/2 inhibitor (IC50: 0.7/0.9 nM), weakly inhibits >180 kinases.</p>Fórmula:C26H23FIN5O4Pureza:98% - 99.96%Cor e Forma:SolidPeso molecular:615.39Ac-DEVD-CHO acetate
<p>Caspase-3 Inhibitor I (N-acetyl-asp-glu-val-asp-al) is a specific inhibitor of Caspase-3.</p>Fórmula:C22H34N4O13Pureza:98.54%Cor e Forma:SolidPeso molecular:562.52Niraparib tosylate
CAS:<p>Niraparib tosylate (MK-4827 (tosylate))(with IC50 of 3.8 nM/2.1 nM) is a selective PARP1/PARP2 inhibitor.</p>Fórmula:C19H20N4O·C7H8O3SPureza:99.34% - 99.87%Cor e Forma:SolidPeso molecular:492.59Iberdomide
CAS:<p>Iberdomide (CC-220) is a modulator of cereblon( IC50 value of 60 nM in a competitive TR-FRET assay).</p>Fórmula:C25H27N3O5Pureza:97.01%Cor e Forma:SolidPeso molecular:449.5Selonsertib
CAS:<p>Selonsertib (GS-4997), an oral ASK1 inhibitor, may have anti-inflammatory, anti-fibrotic, and anti-cancer effects.</p>Fórmula:C24H24FN7OPureza:95.04% - 99.53%Cor e Forma:SolidPeso molecular:445.49Tivantinib
CAS:<p>Tivantinib (ARQ 197) is an orally bioavailable small molecule inhibitor of c-Met with potential antineoplastic activity.</p>Fórmula:C23H19N3O2Pureza:98% - 99.41%Cor e Forma:SolidPeso molecular:369.42Dihydrokaempferol
CAS:<p>Dihydrokaempferol (Aromadendrin) is a natural product. It induces apoptosis and inhibits Bcl-2 and Bcl-xL expression, possesses anti-inflammatory activity.</p>Fórmula:C15H12O6Pureza:97.79% - 99.96%Cor e Forma:SolidPeso molecular:288.25SC-236
CAS:<p>SC-236 (Sc 236) is an orally active and selective inhibitor of COX-2 (IC50 of 0.005 μM and 17.8 μM for COX-2 and COX-1, respectively).</p>Fórmula:C16H11ClF3N3O2SPureza:99.74%Cor e Forma:SolidPeso molecular:401.79SNS-032
CAS:<p>SNS-032 (BMS-387032) is a selective inhibitor of CDK2 and is 10- and 20-fold selective over CDK1/CDK4. SNS-032 is sensitive to CDK7/9, and no effect on CDK6.</p>Fórmula:C17H24N4O2S2Pureza:98.27% - 99.91%Cor e Forma:SolidPeso molecular:380.53NPS-1034
CAS:<p>NPS-1034 is a dual Met/Axl inhibitor with IC50 of 48 nM and 10.3 nM, respectively.</p>Fórmula:C31H23F2N5O3Pureza:98.48%Cor e Forma:SolidPeso molecular:551.54NVP-CGM097
CAS:<p>NVP-CGM097 (CGM097) is an effective and specific MDM2 inhibitor (IC50: 1.7 nM for hMDM2).</p>Fórmula:C38H47ClN4O4Pureza:98.77%Cor e Forma:SolidPeso molecular:659.26Linifanib
CAS:<p>Linifanib (AL-39324) (ABT-869) is a novel, potent ATP-competitive VEGFR/PDGFR inhibitor for KDR (IC50: 4 nM), CSF-1R (IC50: 3 nM), Flt-1/3 (IC50: 3/4 nM) and</p>Fórmula:C21H18FN5OPureza:98% - 98.24%Cor e Forma:SolidPeso molecular:375.4LDC000067
CAS:<p>LDC000067 (LDC067) is a highly specific and selective CDK9 inhibitor with an IC50 value of 44±10 nM.</p>Fórmula:C18H18N4O3SPureza:98.08% - 99.07%Cor e Forma:SolidPeso molecular:370.43Cobimetinib
CAS:<p>Cobimetinib (GDC-0973) is a MEK1 inhibitor with selective and oral activity. Cobimetinib exhibits antitumor activity. Cost-effective and quality-assured.</p>Fórmula:C21H21F3IN3O2Pureza:98% - 99.61%Cor e Forma:SolidPeso molecular:531.31YH239-EE
CAS:<p>YH239-EE, the ethyl ester of YH239, is a potent p53-MDM2 antagonist and an apoptosis inducer.</p>Fórmula:C25H27Cl2N3O4Pureza:99.61%Cor e Forma:SolidPeso molecular:504.41GSK2256098
CAS:<p>GSK2256098 (GTPL7939) is a small molecule FAK kinase inhibitor.</p>Fórmula:C20H23ClN6O2Pureza:99.46% - 99.74%Cor e Forma:SolidPeso molecular:414.89PP1
CAS:<p>PP1 (AGL 1872), a specific and effective Src inhibitor, is with IC50 for Lck/Fyn is 5 nM/ 6 nM, respectively.</p>Fórmula:C16H19N5Pureza:99% - 99.88%Cor e Forma:Off-White To Grey SolidPeso molecular:281.36Nystatin
CAS:<p>Nystatin (Fungicidin) is a topical and oral antifungal agent with activity against many species of yeast and candida albicans, which is used largely to treat</p>Fórmula:C47H75NO17Pureza:69.55% - 99.53%Cor e Forma:Yellow SuspensionPeso molecular:926.1CDDO-Im
CAS:<p>CDDO-Im (TP-235) is an activator of Nrf2 and PPAR (Kis: 232/344 nM for PPARα/PPARγ).</p>Fórmula:C34H43N3O3Pureza:98.3% - 99.61%Cor e Forma:SolidPeso molecular:541.72
