Apoptose
Os inibidores da apoptose são compostos que previnem ou retardam o processo de morte celular programada, conhecido como apoptose. Esses inibidores são vitais no estudo dos mecanismos de sobrevivência celular e são usados para investigar doenças onde a apoptose é desregulada, como câncer, distúrbios neurodegenerativos e doenças autoimunes. Ao modular a apoptose, esses inibidores podem ajudar no desenvolvimento de terapias destinadas a controlar a morte celular. Na CymitQuimica, oferecemos uma ampla seleção de inibidores da apoptose de alta qualidade para apoiar sua pesquisa em biologia celular, oncologia e áreas relacionadas.
Subcategorias de "Apoptose"
- ASK(6 produtos)
- BCL(11 produtos)
- Caspase(125 produtos)
- FOXO1(3 produtos)
- IAP(66 produtos)
- Mdm2(12 produtos)
- PD-1/PD-L1(125 produtos)
- PDK(9 produtos)
- PERK(25 produtos)
- Serina/treonina quinase(15 produtos)
- Survivina(13 produtos)
- TNF(92 produtos)
- c-RET(51 produtos)
- p53(62 produtos)
Exibir 6 mais subcategorias
Foram encontrados 5592 produtos de "Apoptose"
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5'-Methylthioadenosine
CAS:<p>5'-Methylthioadenosine (Methylthioadenosine) is produced from S-adenosylmethionine and behaves as a powful inhibitory product.</p>Fórmula:C11H15N5O3SPureza:99.32% - 99.34%Cor e Forma:SolidPeso molecular:297.33K-Ras(G12C) inhibitor 12
CAS:<p>K-Ras(G12C) inhibitor 12 is an allosteric inhibitor of oncogenic K-Ras(G12C).</p>Fórmula:C15H17ClIN3O3Pureza:97.16%Cor e Forma:SolidPeso molecular:449.67Sclareol
CAS:<p>Sclareol from clary sage inhibits growth and is cytotoxic to many human Y cell lines.</p>Fórmula:C20H36O2Pureza:99.58% - 99.97%Cor e Forma:White Fine PowderPeso molecular:308.5TW-37
CAS:<p>TW-37 is an nonpeptide inhibitor to recombinant Bcl-2, Bcl-xL and Mcl-1 (Ki: 0.29/1.11/0.26 μM).</p>Fórmula:C33H35NO6SPureza:97.06% - ≥95%Cor e Forma:SolidPeso molecular:573.7Eltrombopag
CAS:<p>Eltrombopag (SB-497115-GR), an orally active thrombopoietin receptor agonist with megakaryopoiesis stimulating activity, binds to and stimulates the platelet</p>Fórmula:C25H22N4O4Pureza:99.27%Cor e Forma:Orange To Red SolidPeso molecular:442.47PRLX-93936
CAS:<p>PRLX-93936 is a selective Ras pathway protein inhibitor that modulates RAS/JNK pathway-associated protein phosphorylation, anticancer activity.</p>Fórmula:C21H24N4O2Cor e Forma:SolidPeso molecular:364.44Solasodine
CAS:<p>Solasodine, a toxic alkaloid from Solanaceae, kills HeLa cervical cancer and U937 leukemia cells.</p>Fórmula:C27H43NO2Pureza:99.64% - 99.94%Cor e Forma:SolidPeso molecular:413.64SB 202190
CAS:<p>SB 202190 (FHPI) is a p38 MAPK inhibitor that inhibits p38α and p38β2 (IC50=50/100 nM) selectively and cell-permeably.</p>Fórmula:C20H14FN3OPureza:98% - 99.84%Cor e Forma:Pale YellowPeso molecular:331.34SRS11-92
CAS:<p>SRS11-92 (AA9) is a ferroptosis inhibitor and a derivative of ferrostatin-1</p>Fórmula:C22H28N2O2Pureza:98.58%Cor e Forma:SolidPeso molecular:352.47Y-27632 dihydrochloride
CAS:<p>View and buy Y-27632 dihydrochloride from TargetMol.Y-27632 is a selective inhibitor of ROCKs.Cited in 10 publications.</p>Fórmula:C14H21N3O·2HClPureza:97.96% - 99.98%Cor e Forma:SolidPeso molecular:320.26Licofelone
CAS:<p>Licofelone (ML-3000) is a dual COX/LOX inhibitor potentially for the treatment of osteoarthritis.</p>Fórmula:C23H22ClNO2Pureza:99.25%Cor e Forma:Yellowish SolidPeso molecular:379.88Astaxanthin
CAS:<p>Astaxanthin, a keto-carotenoid and xanthophyll, offers antioxidant benefits, present in red aquatic species, and used as a colorant in animal feed.</p>Fórmula:C40H52O4Pureza:95.1% - 99.79%Cor e Forma:Needles From Acetone/Light Petroleum SolidPeso molecular:596.84Otenaproxesul
CAS:<p>Otenaproxesul (ATB 346) is a novel hydrogen sulphide-releasing derivative of naproxen with markedly reduced toxicity.</p>Fórmula:C21H19NO3SPureza:98.76% - 99.13%Cor e Forma:SolidPeso molecular:365.45Ganoderic acid D
CAS:<p>Ganoderic acid D, a Ganoderma component, inhibits HeLa cell growth with an IC50 of 17.3µM after 48h.</p>Fórmula:C30H42O7Pureza:98.06% - 99.98%Cor e Forma:SolidPeso molecular:514.65EGFR-IN-12
CAS:<p>EGFR-IN-12 (EGFR Inhibitor) is a cell permeable and selective inhibitor of EGFR kinase (IC50: 21 nM) and blocks receptor autophosphorylation in cells.</p>Fórmula:C21H18F3N5OPureza:98.3% - 99.76%Cor e Forma:SolidPeso molecular:413.4HJC0152 hydrochloride
CAS:<p>HJC0152 hydrochloride (HJC0152) is a signal transducer and activator of transcription 3 (STAT3) inhibitor.</p>Fórmula:C15H14Cl3N3O4Pureza:99.01% - 99.06%Cor e Forma:SolidPeso molecular:406.643-Nitropropanoic acid
CAS:<p>3-Nitropropanoic acid (Bovinocidin) is an irreversible inhibitor of succinate dehydrogenase.</p>Fórmula:C3H5NO4Pureza:98.35% - 99.94%Cor e Forma:Crystals From Chloroform Physical Description Golden Crystals (From Chloroform) (Ntp 1992)Peso molecular:119.08Tripterin
CAS:<p>Tripterin (Celastrol) is an proteasome inhibitor for the chymotrypsin-like activity of a purified 20S proteasome with antioxidant and anti-inflammatory effects.</p>Fórmula:C29H38O4Pureza:98.56% - 99.8%Cor e Forma:Red Crystalline PowderPeso molecular:450.61Ginkgolide B
CAS:<p>Ginkgolide B (BN-52021) is a PAFR antagonist(IC50=3.6 μM) isolated from Ginkgo biloba.</p>Fórmula:C20H24O10Pureza:98.66% - 99.81%Cor e Forma:White Crystal PowderPeso molecular:424.4AZD-3463
CAS:<p>AZD-3463 (ALK/IGF1R inhibitor) , an orally bioavailable ALK inhibitor (Ki: 0.75 nM), can inhibit IGF1R with equivalent potency.</p>Fórmula:C24H25ClN6OPureza:99.13%Cor e Forma:SolidPeso molecular:448.95Demethylzeylasteral
CAS:<p>Demethylzeylasteral (T-96), isolated from Tripterygium wilfordii, has anti-inflammatory, immunosuppressive and anti-tumor activities.</p>Fórmula:C29H36O6Pureza:98.74% - 99.82%Cor e Forma:SolidPeso molecular:480.59Rosiglitazone
CAS:<p>Rosiglitazone (BRL49653) is a PPARγ agonist, TRPC5 activator, and TRPM3 inhibitor with oral activity.</p>Fórmula:C18H19N3O3SPureza:98.61% - 99.87%Cor e Forma:White To Off-White Crystalline PowderPeso molecular:357.43Mito-LND
CAS:<p>Mito-LND (Mito-Loidamine) is an orally active and mitochondria-targeted inhibitor of oxidative phosphorylation.</p>Fórmula:C43H45BrCl2N3OPPureza:97.25% - 98.34%Cor e Forma:SolidPeso molecular:801.62Citronellyl acetate
CAS:<p>Citronellyl acetate is a natural product</p>Fórmula:C12H22O2Pureza:98%Cor e Forma:LiquidPeso molecular:198.30Dubermatinib
CAS:<p>Dubermatinib (TP0903) is a potent and selective Axl kinase inhibitor.</p>Fórmula:C24H30ClN7O2SPureza:98.65% - 99.58%Cor e Forma:SolidPeso molecular:516.06SEC inhibitor KL-1
CAS:<p>KL-1, a potent SEC inhibitor, disrupts the AFF4-CCNT1 interaction with a Ki of 3.48 μM, selectively targeting the SEC.</p>Fórmula:C18H16ClNO4Pureza:97.42%Cor e Forma:SolidPeso molecular:345.78WYE-354
CAS:<p>WYE-354 is a selective mTOR inhibitor (IC50=5 nM), targeting mTORC1/C2 over PI3Kα (>100x) and PI3Kγ (>500x), sparing P-AKT(T308).</p>Fórmula:C24H29N7O5Pureza:97.86% - 99.61%Cor e Forma:SolidPeso molecular:495.53Sophocarpine
CAS:<p>Sophocarpine, a major ingredient of Sophora alopecuroides, has a wide range of pharmacological effects.</p>Fórmula:C15H22N2OPureza:99.89%Cor e Forma:SolidPeso molecular:246.35GSK 872 hydrochloride
CAS:<p>GSK872 HCl（1346546-69-7 free base） (GSK2399872A) is an effective and specific RIP3 kinase inhibitor.</p>Fórmula:C19H18ClN3O2S2Pureza:99%Cor e Forma:SolidPeso molecular:419.94CDPPB
CAS:<p>CDPPB is a modulator of mGluR5 positive allosteric(with an EC50 of 27 nM in Chinese hamster ovary cells expressing human mGluR5).</p>Fórmula:C23H16N4OPureza:99.16%Cor e Forma:SolidPeso molecular:364.4Momelotinib
CAS:<p>Momelotinib (LM-1149), an oral JAK1/2 inhibitor with IC50s 11/18 nM, blocks ATP binding, disrupting JAK-STAT pathway and reducing tumor growth.</p>Fórmula:C23H22N6O2Pureza:97.47% - 99.56%Cor e Forma:SolidPeso molecular:414.46SJ-172550
CAS:<p>SJ-172550 is a small molecule inhibitor of MDMX (EC50: 5 μM).</p>Fórmula:C22H21ClN2O5Pureza:99.87%Cor e Forma:SolidPeso molecular:428.87NUN82647
CAS:<p>NUN82647 (CU-242) is an Inhibitor of cell cycle at G2 phase, and apoptosis inducer.</p>Fórmula:C15H13N3O2SPureza:98.91%Cor e Forma:SolidPeso molecular:299.35Z-VAD(OMe)-FMK
CAS:<p>View and buy Z-VAD(OMe)-FMK from TargetMol.Z-VAD(OMe)-FMK is a cell-permeable and irreversible pan-caspase inhibitor.Cited in 10 publications.</p>Fórmula:C22H30FN3O7Pureza:95.92% - 99.71%Cor e Forma:SolidPeso molecular:467.49Pevonedistat
CAS:<p>Pevonedistat (MLN4924) is a potent and selective NEDD8 activating enzyme (NAE) inhibitor (IC50=4.7 nM).</p>Fórmula:C21H25N5O4SPureza:95% - 99.92%Cor e Forma:SolidPeso molecular:443.52Isosorbide Mononitrate
CAS:<p>Isosorbide Mononitrate (Corangin) is a Nitrate Vasodilator, dilating the blood vessels so as to reduce the blood pressure.</p>Fórmula:C6H9NO6Pureza:98.16%Cor e Forma:Isosorbide-5-Mononitrate Is A Crystalline Solid It Is Very Flammable And May Be Toxic By IngestionPeso molecular:191.14Fluazinam
CAS:<p>Fluazinam: a pyridinamine fungicide, broad-spectrum, strongly inhibits S. sclerotiorum mycelial growth.</p>Fórmula:C13H4Cl2F6N4O4Pureza:98% - 99.7%Cor e Forma:Light Yellow CrystalsPeso molecular:465.09Saquinavir
CAS:<p>Saquinavir (Ro 31-8959) is a potent HIV protease inhibitor, is an antiretroviral drug used together with other medications to treat or prevent HIV/AIDS.</p>Fórmula:C38H50N6O5Pureza:99.50% - >99.99%Cor e Forma:SolidPeso molecular:670.84Tilmicosin phosphate
CAS:<p>Tilmicosin phosphate, a macrolide antibiotic, is used to treat cattle for pathogens that cause Bovine Respiratory Disease.</p>Fórmula:C46H83N2O17PPureza:95.29% - 97.13%Cor e Forma:Light Yellow PowderPeso molecular:967.1Elevenostat
CAS:<p>Elevenostat is an HDAC11-selective inhibitor with an IC50 value of 0.235 µM.</p>Fórmula:C16H17N3O4Pureza:95% - 96.14%Cor e Forma:SolidPeso molecular:315.32D-Saccharic acid 1,4-lactone hydrate
CAS:<p>D-Saccharic acid 1,4-lactone hydrate inhibits β-glucuronidase (IC50=48.4 μM); has anticarcinogenic, detoxifying, antioxidant traits.</p>Fórmula:C17H20ClN3OPureza:99.49% - ≥98%Cor e Forma:SolidPeso molecular:317.81C-DIM12
CAS:<p>C-DIM12 boosts Nurr1 gene expression, heightens Nurr1 protein in neurons, and improves survival against 6-OHDA.</p>Fórmula:C23H17ClN2Pureza:97.72% - ≥95%Cor e Forma:SolidPeso molecular:356.85COTI-2
CAS:<p>COTI-2, an orally available thiosemicarbazone, is an activator of mutant forms of the p53 protein with potential antineoplastic activity.</p>Fórmula:C19H22N6SPureza:99% - 99.55%Cor e Forma:SolidPeso molecular:366.48Dantrolene sodium hemiheptahydrate
CAS:<p>Dantrolene depresses excitation-contraction coupling in skeletal muscle by binding to the ryanodine receptor 1 and decreasing intracellular calcium</p>Fórmula:C14H9N4NaO5·5H2OPureza:99.72%Cor e Forma:Orange PowderPeso molecular:399.29GYY4137
CAS:<p>GYY4137 (GYY 4137 morpholine salt) is a novel water-soluble and slow releasing H2S donor with antihypertensive, anti-inflammatory and anticancer activity.</p>Fórmula:C11H16NO2PS2·C4H9NOPureza:95.54% - 99.97%Cor e Forma:SolidPeso molecular:376.47DIM-C-pPhCO2Me
CAS:<p>DIM-C-pPhCO2Me is a nuclear receptor 4A1 (NR4A1) antagonist.</p>Fórmula:C25H20N2O2Pureza:99.55% - 99.86%Cor e Forma:SolidPeso molecular:380.44ASP3026
CAS:<p>ASP3026 has been used in trials studying the treatment of Solid Tumor, B-Cell Lymphoma, Advanced Malignancies,and Positive for Anaplastic Lymphoma Kinase.</p>Fórmula:C29H40N8O3SPureza:98.78% - 99.81%Cor e Forma:SolidPeso molecular:580.74Desciclovir
CAS:<p>Desciclovir (DCV), a prodrug of the antiherpetic agent acyclovir (ACV), is converted in humans to ACV, presumably by xanthine oxidase.</p>Fórmula:C8H11N5O2Pureza:99.54%Cor e Forma:SolidPeso molecular:209.212-HBA
CAS:<p>2-HBA, a synthetic analog of curcumin, is an indirect inducer of enzymes that catalyze detoxification reactions through the Keap1-Nrf2-ARE pathway.</p>Fórmula:C17H14O3Pureza:99.76%Cor e Forma:SolidPeso molecular:266.29Phenazine methylsulfate
CAS:<p>Phenazine methylsulfate is anti-bacterial agents.</p>Fórmula:C14H14N2O4SPureza:97.67% - >99.99%Cor e Forma:Yellow CrystallinePeso molecular:306.34Piperacetazine
CAS:<p>Piperacetazine (Piperacetazinum), an antipsychotic prodrug, is used forschizophrenia.</p>Fórmula:C24H30N2O2SPureza:99.9% - 99.92%Cor e Forma:SolidPeso molecular:410.57(E/Z)-Necrosulfonamide
CAS:<p>(E/Z)-Necrosulfonamide is a novel inhibitor of MLKL.</p>Fórmula:C18H15N5O6S2Pureza:97.62% - 98%Cor e Forma:SolidPeso molecular:461.47PD184161
CAS:<p>PD184161 is a novel, orally-active MEK inhibitor. PD184161 inhibited MEK activity (IC50 = 10-100 nM) in a time- and concentration-dependent manner[1].</p>Fórmula:C17H13BrClF2IN2O2Pureza:99.40%Cor e Forma:SolidPeso molecular:557.56Rhapontin
CAS:<p>Rhapontin may reduce liver fat and better blood sugar/lipids, showing potential for treating type 2 diabetes.</p>Fórmula:C21H24O9Pureza:99% - 99.91%Cor e Forma:Light YellowPeso molecular:420.41Euscaphic acid
CAS:<p>Euscaphic acid has anti-diabetic and anti-inflammatory effects, blocking IKK/MAPKs and NF-κB activation by disrupting TRAF6/IRAK1/TAK1 clustering.</p>Fórmula:C30H48O5Pureza:98.93%Cor e Forma:SolidPeso molecular:488.7Pitstop 2
CAS:<p>Pitstop2 is an amphipathic protein-bound inhibitor of the clathrin terminal domain. Pitstop2 has antitumor activity. Cost-effective, quality assurance.</p>Fórmula:C20H13BrN2O3S2Pureza:99.54%Cor e Forma:SolidPeso molecular:473.36Capmatinib 2HCl
CAS:<p>Capmatinib 2HCl (INC-280 2HCl), a c-MET inhibitor, is potent (IC50 = 0.13 nM), highly specific, and induces apoptosis in tumor cells.</p>Fórmula:C23H19Cl2FN6OPureza:98.80%Cor e Forma:SolidPeso molecular:485.34NS-1619
CAS:<p>NS1619 have cardio-protective effects after ischemia-reperfusion injury.</p>Fórmula:C15H8F6N2O2Pureza:97.66% - 98%Cor e Forma:SolidPeso molecular:362.23GSK-923295
CAS:<p>GSK923295 is a selective allosteric inhibitor of CENP-E kinesin motor ATPase(Ki=3.2 nM).</p>Fórmula:C32H38ClN5O4Pureza:96.22% - 98.02%Cor e Forma:SolidPeso molecular:592.13ASK1-IN-2
CAS:<p>ASK1-IN-2: oral ASK1 inhibitor, IC50 32.8 nM, potential ulcerative colitis treatment.</p>Fórmula:C19H17FN6OPureza:98.79%Cor e Forma:SolidPeso molecular:364.38Tenovin-1
CAS:<p>Tenovin-1 inhibits protein-deacetylating activities of SirT1 and SirT2 and protects against MDM2-mediated p53 degradation, which involves ubiquitination.</p>Fórmula:C20H23N3O2SPureza:99.33%Cor e Forma:SolidPeso molecular:369.48Cyclovirobuxine D
CAS:<p>Cyclovirobuxine D (Bebuxine) is extracted from Buxus microphylla.</p>Fórmula:C26H46N2OPureza:97.78% - 98%Cor e Forma:SolidPeso molecular:402.66Iberdomide
CAS:<p>Iberdomide (CC-220) is a modulator of cereblon( IC50 value of 60 nM in a competitive TR-FRET assay).</p>Fórmula:C25H27N3O5Pureza:97.01%Cor e Forma:SolidPeso molecular:449.5Navitoclax
CAS:<p>View and buy Navitoclax from TargetMol.Navitoclax (ABT-263) is a potent, orally bioavailable Bcl-2 family protein inhibitor that avidly binds Bcl-2.Cited in 4 publications.</p>Fórmula:C47H55ClF3N5O6S3Pureza:95.82% - >99.99%Cor e Forma:Pale Yellow SolidPeso molecular:974.61Dihydrokaempferol
CAS:<p>Dihydrokaempferol (Aromadendrin) is a natural product. It induces apoptosis and inhibits Bcl-2 and Bcl-xL expression, possesses anti-inflammatory activity.</p>Fórmula:C15H12O6Pureza:97.79% - 99.96%Cor e Forma:SolidPeso molecular:288.25SC-236
CAS:<p>SC-236 (Sc 236) is an orally active and selective inhibitor of COX-2 (IC50 of 0.005 μM and 17.8 μM for COX-2 and COX-1, respectively).</p>Fórmula:C16H11ClF3N3O2SPureza:99.74%Cor e Forma:SolidPeso molecular:401.79NVP-TNKS656
CAS:<p>NVP-TNKS656 (TNKS656) is a highly potent, selective, and orally active TNKS2 inhibitor.</p>Fórmula:C27H34N4O5Pureza:99.59%Cor e Forma:SolidPeso molecular:494.58GSK2256098
CAS:<p>GSK2256098 (GTPL7939) is a small molecule FAK kinase inhibitor.</p>Fórmula:C20H23ClN6O2Pureza:99.46% - 99.74%Cor e Forma:SolidPeso molecular:414.89ZM-447439
CAS:<p>ZM 447439 selectively inhibits Aurora A/B (IC50: 110/130 nM); 8x less effective on MEK1, Src, Lck; minimal impact on CDK1/2/4, Plk1, Chk1.</p>Fórmula:C29H31N5O4Pureza:99.11% - 99.59%Cor e Forma:Pale Yellow SolidPeso molecular:513.59MK-4101
CAS:<p>MK-4101 inhibits Hedgehog pathway, causing apoptosis and reduced proliferation in cancer cells.</p>Fórmula:C24H24F5N5OPureza:98.2% - 99.13%Cor e Forma:SolidPeso molecular:493.47Vatalanib dihydrochloride
CAS:<p>Vatalanib dihydrochloride (PTK787 dihydrochloride)(IC50=37 nM) is an inhibitor of VEGFR2/KDR.</p>Fórmula:C20H15ClN4·2HClPureza:99.16%Cor e Forma:White To Off-White Crystalline PowderPeso molecular:419.73XL019
CAS:<p>XL019 is a potent and selective JAK2 inhibitor with IC50 of 2.2 nM, 100 fold selectivity over JAK1.</p>Fórmula:C25H28N6O2Pureza:99.19%Cor e Forma:SolidPeso molecular:444.53tubuloside B
CAS:<p>Tubuloside B from Cistanche salsa stems guards SH-SY5Y cells against TNFalpha-induced apoptosis.</p>Fórmula:C31H38O16Pureza:97.59% - 99.72%Cor e Forma:SolidPeso molecular:666.62PF-4989216
CAS:<p>PF-4989216 is a potent and selective PI3K inhibitor with IC50 of 2 nM, 142 nM, 65 nM, 1 nM, and 110 nM for p110α, p110β, p110γ, p110δ, and VPS34, respectively.</p>Fórmula:C18H13FN6OSPureza:99.85%Cor e Forma:SolidPeso molecular:380.4Isosilybin A
CAS:<p>Isosilybin A is a partial PPARγ agonist, it significantly induced ABCA1 protein expression, it inhibited both monophenolase (IC50=1.7-7.6μM) and diphenolase (</p>Fórmula:C25H22O10Pureza:98.79%Cor e Forma:SolidPeso molecular:482.442,5-dimethyl Celecoxib
CAS:<p>2,5-dimethyl Celecoxib, a derivative targeting mPGES-1, inhibits PGE2 synthesis in inflammation.</p>Fórmula:C18H16F3N3O2SPureza:99.85%Cor e Forma:SolidPeso molecular:395.4Mitoxantrone
CAS:<p>Mitoxantrone: anthracenedione antibiotic, disrupts DNA/RNA replication, binds to topoisomerase II, less cardiotoxic than doxorubicin.</p>Fórmula:C22H28N4O6Pureza:96.29% - 98.74%Cor e Forma:Blue PowderPeso molecular:444.48JQ-1 (carboxylic acid)
CAS:<p>JQ-1 (carboxylic acid) is a cell-permeable BRD4 inhibitor with IC50s of 77 nM for BRD4(1) and 33 nM for BRD4(2)</p>Fórmula:C19H17ClN4O2SPureza:99.14% - 99.9%Cor e Forma:SolidPeso molecular:400.88GS-444217
CAS:<p>GS-444217 is a selective ATP-competitive inhibitor of apoptosis signal-regulating kinase 1 (ASK1, IC50: 2.87 nM).</p>Fórmula:C23H21N7OPureza:99.08%Cor e Forma:SolidPeso molecular:411.46Kinsenoside
CAS:<p>Kinsenoside ((+)-Kinsenoside) shows significant antihepatotoxic, and anti-inflammatory activities.</p>Fórmula:C10H16O8Pureza:99.2% - >99.99%Cor e Forma:SolidPeso molecular:264.23PS-1145
CAS:<p>PS-1145 (IKK Inhibitor X) is a specific IKK inhibitor with IC50 of 88 nM.</p>Fórmula:C17H11ClN4OPureza:98.81% - >99.99%Cor e Forma:SolidPeso molecular:322.75RAF265
CAS:<p>RAF265 (CHIR-265) inhibits C-Raf/B-Raf/V600E (IC50: 3-60 nM), blocks VEGFR2 (EC50: 30 nM), in Phase 2 trials.</p>Fórmula:C24H16F6N6OPureza:99.56%Cor e Forma:SolidPeso molecular:518.41Cucurbitacin B
CAS:<p>Cucurbitacin B (Cuc B) has profound in vitro and in vivo antiproliferative effects against human pancreatic Y cells.</p>Fórmula:C32H46O8Pureza:97.1% - 99.33%Cor e Forma:SolidPeso molecular:558.7Epoxomicin
CAS:<p>Epoxomicin, a selective proteasome inhibitor, chiefly blocks CH-L activity, mildly affecting T-L and PGPH at lower rates.</p>Fórmula:C28H50N4O7Pureza:98.65% - 98.86%Cor e Forma:White To Off-White SolidPeso molecular:554.72Eprenetapopt
CAS:<p>Eprenetapopt (PRIMA-1Met) restores wild-type conformation and function to mutant p53, and triggers apoptosis in tumor cells.</p>Fórmula:C10H17NO3Pureza:98.75% - 99.57%Cor e Forma:SolidPeso molecular:199.25Scopoletin
CAS:<p>Scopoletin (Esculetin 6-methyl ether) is a plant growth factor derived from the root of Scopolia carniolica, inhibits of acetylcholinesterase (AChE).</p>Fórmula:C10H8O4Pureza:97.06% - 99.88%Cor e Forma:Yellow To Beige Crystalline PowderPeso molecular:192.17Capmatinib 2HCl.H2O
CAS:<p>Capmatinib 2HCl.H2O (NVP-INC280 2HCl.H2O) is an orally bioavailable inhibitor of the proto-oncogene c-Met (HGFR)with potential antineoplastic activity.</p>Fórmula:C23H21Cl2FN6O2Pureza:99.77%Cor e Forma:SolidPeso molecular:503.36Quinidine sulfate dihydrate
CAS:<p>Quinidine sulfate dihydrate (Pitayine Sodium) is a potent and selective cytochrome P450db inhibitor</p>Fórmula:C40H54N4O10SPureza:99.85%Cor e Forma:White To Light Yellow Crystal PowdePeso molecular:782.9Navtemadlin
CAS:<p>Navtemadlin (AMG232) is a potent, selective and orally available inhibitor of p53-MDM2 interaction (IC50: 0.6 nM).Cost-effective and quality-assured.</p>Fórmula:C28H35Cl2NO5SPureza:95.55% - 99.08%Cor e Forma:SolidPeso molecular:568.55Paederosidic acid
CAS:<p>Paederosidic acid shows anti-tumor, anticonvulsant, and sedative properties, may treat epilepsy by modulating brain GABA and glutamate levels.</p>Fórmula:C18H24O12SPureza:98% - 99.56%Cor e Forma:SolidPeso molecular:464.44DMU-212
CAS:<p>DMU-212, a Resveratrol derivative, has antimitotic, antiproliferative, antioxidant properties; induces apoptosis via ERK1/2.</p>Fórmula:C18H20O4Pureza:99.86%Cor e Forma:SolidPeso molecular:300.35(20S)-Protopanaxatriol
CAS:<p>(20S)-Protopanaxatriol (g-PPT)(g-PPT), a metabolite of ginsenoside, could regulate endothelial cell functions through the estrogen receptor and glucocorticoid</p>Fórmula:C30H52O4Pureza:95% - 99%Cor e Forma:SolidPeso molecular:476.73OsMundacetone
CAS:<p>OsMundacetone (4-(3,4-Dihydroxyphenyl)-3-buten-2-one) is a natual product isolated from Rhizoma osmundae.</p>Fórmula:C10H10O3Pureza:99.59% - ≥95%Cor e Forma:SolidPeso molecular:178.18DL-Buthionine-(S,R)-sulfoximine
CAS:<p>DL-Buthionine-(S,R)-sulfoximine (Butionine sulfoximine) is an inhibitor of γ-glutamylcysteine synthetase for the treatment of solid tumors.</p>Fórmula:C8H18N2O3SPureza:98% - 99.64%Cor e Forma:White Fine PowderPeso molecular:222.31NVP-TAE 226
CAS:<p>NVP-TAE 226: Potent FAK inhibitor, IC50=5.5nM, stronger vs Pyk2, IC50=3.5nM, weaker against IGF-1R, InsR, c-Met, ALK.</p>Fórmula:C23H25ClN6O3Pureza:98.07% - 98.78%Cor e Forma:SolidPeso molecular:468.94Orantinib
CAS:<p>Orantinib (NSC 702827) , a excellent effective against PDGFR autophosphorylation with Ki of 8 nM, also highly inhibits Flk-1 and FGFR1 trans-phosphorylation.</p>Fórmula:C18H18N2O3Pureza:98.92% - 99.52%Cor e Forma:SolidPeso molecular:310.35Mycophenolate Mofetil
CAS:<p>Mycophenolate Mofetil (TM-MMF), is an immunosuppressive agent, 2-morpholinoethyl ester of MPA, and an inhibitor of inosine monophosphate dehydrogenase (IMPDH).</p>Fórmula:C23H31NO7Pureza:98.27% - 99.85%Cor e Forma:White To Off-White Crystalline PowderPeso molecular:433.49Carfilzomib
CAS:<p>Carfilzomib (PR-171) is a proteasome inhibitor that irreversibly binds to the chymotrypsin of the 20S proteasome.</p>Fórmula:C40H57N5O7Pureza:99.6% - 99.84%Cor e Forma:SolidPeso molecular:719.91PUMA BH3 Free base
<p>PUMA BH3 acetate (PUMA BH3 Free base) is a p53 positive regulator of apoptosis (PUMA) BH3 domain polypeptide that acts as a direct activator of Bak with a Kd of</p>Fórmula:C130H206N42O45SPureza:96.64%Cor e Forma:SolidPeso molecular:3109.35
