Apoptose
Os inibidores da apoptose são compostos que previnem ou retardam o processo de morte celular programada, conhecido como apoptose. Esses inibidores são vitais no estudo dos mecanismos de sobrevivência celular e são usados para investigar doenças onde a apoptose é desregulada, como câncer, distúrbios neurodegenerativos e doenças autoimunes. Ao modular a apoptose, esses inibidores podem ajudar no desenvolvimento de terapias destinadas a controlar a morte celular. Na CymitQuimica, oferecemos uma ampla seleção de inibidores da apoptose de alta qualidade para apoiar sua pesquisa em biologia celular, oncologia e áreas relacionadas.
Subcategorias de "Apoptose"
- ASK(6 produtos)
- BCL(11 produtos)
- Caspase(125 produtos)
- FOXO1(3 produtos)
- IAP(66 produtos)
- Mdm2(12 produtos)
- PD-1/PD-L1(125 produtos)
- PDK(9 produtos)
- PERK(25 produtos)
- Serina/treonina quinase(15 produtos)
- Survivina(13 produtos)
- TNF(92 produtos)
- c-RET(51 produtos)
- p53(62 produtos)
Exibir 6 mais subcategorias
Foram encontrados 5592 produtos de "Apoptose"
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COG-1410 acetate
<p>COG-1410 acetate is an apolipoprotein E-derived peptide and can be used in studies about neurological diseases.</p>Fórmula:C66H125N21O16Pureza:99.61%Cor e Forma:SolidPeso molecular:1468.83Apoptosis inducer 13
<p>Apoptosis Inducer 13 (Compound Ru4) promotes apoptosis in cancer cells while also suppressing their migration and invasion.</p>Fórmula:C59H54ClF6N8O4PRuPureza:98%Cor e Forma:SolidPeso molecular:1220.6cpm-1285
CAS:<p>CPM-1285 induces apoptosis by effectively inhibiting the function of intracellular Bcl-2 and associated death antagonists.</p>Fórmula:C153H240N44O42SPureza:98%Cor e Forma:SolidPeso molecular:3399.88MK-0731
CAS:<p>MK-0731 inhibits kinesin spindle protein, disrupting mitosis and triggering apoptosis in KSP-overexpressing tumor cells.</p>Fórmula:C25H28F3N3O2Cor e Forma:SolidPeso molecular:459.5Antitumor photosensitizer-4
<p>Antitumor Photosensitizer-4 (compound 10b), a conjugate of dasatinib and imatinib, serves as a potent tyrosine kinase inhibitor (TKI) targeting ABCG2.</p>Fórmula:C65H77ClN12O11SPureza:98%Cor e Forma:SolidPeso molecular:1269.9Kurzipene D
CAS:<p>Kurzipene D: anticancer, induces apoptosis, halts HepG2 at S phase, anti-tumor in zebrafish, inhibits tumor growth and spread.</p>Fórmula:C26H36O8Cor e Forma:SolidPeso molecular:476.56FKBP12 Ligand-Linker Conjugate 1
CAS:<p>FKBP12 Ligand-Linker Conjugate 1 is a complex comprising a target protein ligand for FKBP12 and a linker, which is utilized in the synthesis of the PROTAC degrader MC-25B.</p>Fórmula:C42H63N3O11Cor e Forma:SolidPeso molecular:785.9632,5-Dimethylcyclohexa-2,5-diene-1,4-dione
CAS:<p>2,5-Dimethylcyclohexa-2,5-diene-1,4-dione inhibits the viability of HL60 and K562 cells and exhibits antibacterial and anticancer properties.</p>Fórmula:C8H8O2Pureza:99.80%Cor e Forma:SolidPeso molecular:136.15[Au(L4)(CyJohnPhos)]SbF6
<p>[Au(L4)(CyJohnPhos)]SbF6 is a gold-containing compound that exhibits inhibitory effects on cyclooxygenase-1/2 (COX-1/2), suppresses the proliferation of colon cancer cells Caco2-/TC7 with an IC50 of 0.98 μM, and induces cell apoptosis (apoptosis). Additionally, [Au(L4)(CyJohnPhos)]SbF6 acts as an inhibitor of thioredoxin reductase (TrxR) and demonstrates antioxidative activity by modulating ROS levels.</p>Fórmula:C44H56AuF6NO4PSSbCor e Forma:SolidPeso molecular:1158.68ECDD-S18
<p>ECDD-S18 (compound ECDD-S18) induces apoptosis in a dose-dependent manner, effectively targeting the vacuolar ATPase (V-ATPase) and impairing lysosomal acidification.</p>Fórmula:C35H31BrO12Cor e Forma:SolidPeso molecular:723.52Tubulin polymerization-IN-70
<p>Tubulin polymerization-IN-70 (compound Q19) is an effective inhibitor of tubulin polymerization. This compound exerts antiproliferative properties by targeting the colchicine binding site on tubulin, thereby inhibiting its polymerization. Tubulin polymerization-IN-70 also induces apoptosis and cell cycle arrest at the G2/M phase. Additionally, it triggers a decrease in mitochondrial membrane potential and elevates levels of reactive oxygen species (ROS). Moreover, Tubulin polymerization-IN-70 possesses anti-angiogenic and anticancer activities.</p>Fórmula:C25H23N3O2Cor e Forma:SolidPeso molecular:397.47Thalidomide-O-C2-acid
CAS:<p>Thalidomide-O-C2-acid: E3 ligase ligand-linker for PROTAC, with cereblon-derived Thalidomide component.</p>Fórmula:C16H14N2O7Cor e Forma:SolidPeso molecular:346.2916Apoptosis inducer 30
<p>Apoptosisinducer 30 (Compound 15a) acts as an anticancer agent. It induces apoptosis in MCF-7 cells through the mitochondrial pathway. This compound elevates intracellular levels of reactive oxygen species (ROS), decreases mitochondrial membrane potential, and arrests the cell cycle at the G0/G1 phase. Apoptosisinducer 30 inhibits cell growth, with an IC50 value of 0.32 μM against MCF-7 cells, and suppresses tumor growth in a mouse breast cancer model.</p>Fórmula:C52H69BrNO4PCor e Forma:SolidPeso molecular:882.99Taccalonolide E
CAS:<p>Taccalonolide E is a microtubule stabilizer and induces cancer cell apoptosis .</p>Fórmula:C34H44O12Cor e Forma:SolidPeso molecular:644.71Quercetin-d3
<p>Quercetin-d3 hydrate, a deuterated form of Quercetin hydrate, acts as a flavonoid that stimulates recombinant SIRT1 and serves as a PI3K inhibitor. The compound specifically exhibits IC50 values of 2.4 μM, 3.0 μM, and 5.4 μM against PI3Kγ, PI3Kδ, and PI3Kβ, respectively.</p>Fórmula:C15H9D3O8Cor e Forma:SolidPeso molecular:323.27Schisandronic acid
CAS:<p>Schisandronic acid is a triterpenoid acid isolated from the stems of Schisandra propinqua.</p>Fórmula:C30H46O3Cor e Forma:SolidPeso molecular:454.68eIF4E-IN-1
CAS:<p>eIF4E-IN-1 inhibits eIF4E and boosts immunity by targeting PD-1, PD-L1, LAG3, TIM3, IDO, aiding cancer and infection treatment.</p>Fórmula:C33H28ClF3N6O4SCor e Forma:SolidPeso molecular:697.13Zapalog
CAS:<p>Zapalog: photocleavable dimerizer controlling instant protein interactions.</p>Fórmula:C58H73N7O15Pureza:98%Cor e Forma:SolidPeso molecular:1108.24CQ-ER
<p>CQ-ER is a Coumarin-quinazolinone-based photosensitizer targeting the endoplasmic reticulum (ER). It induces ferroptosis, thereby enhancing photodynamic therapy (PDT).</p>Fórmula:C33H33N7O6SCor e Forma:SolidPeso molecular:655.72JPS014 TFA
<p>JPS014 TFA, a benzamide-based Von Hippel-Lindau (VHL) E3-ligase proteolysis targeting chimera (PROTAC), effectively degrades class I histone deacetylase (HDAC</p>Fórmula:C48H60F3N7O9SPureza:98%Cor e Forma:SolidPeso molecular:968.09
