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Apoptose

Apoptose

Os inibidores da apoptose são compostos que previnem ou retardam o processo de morte celular programada, conhecido como apoptose. Esses inibidores são vitais no estudo dos mecanismos de sobrevivência celular e são usados para investigar doenças onde a apoptose é desregulada, como câncer, distúrbios neurodegenerativos e doenças autoimunes. Ao modular a apoptose, esses inibidores podem ajudar no desenvolvimento de terapias destinadas a controlar a morte celular. Na CymitQuimica, oferecemos uma ampla seleção de inibidores da apoptose de alta qualidade para apoiar sua pesquisa em biologia celular, oncologia e áreas relacionadas.

Subcategorias de "Apoptose"

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Foram encontrados 5592 produtos de "Apoptose"

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  • BLU-222

    CAS:
    <p>BLU-222 is a potent, selective and orally active CDK2 inhibitor. BLU-222 shows robust antitumor activity.</p>
    Fórmula:C15H17F2N7O2
    Pureza:99.17% - 99.92%
    Cor e Forma:Soild
    Peso molecular:365.34
  • S-Adenosyl-L-methionine iodide

    CAS:
    <p>S-(5'-Adenosyl)-L-methionine iodide, also known as S-Adenosyl-L-methionine iodide, is a vital methyl donor present in all living organisms [1].</p>
    Fórmula:C15H23IN6O5S
    Cor e Forma:Solid
    Peso molecular:526.35
  • Eciskafusp alfa

    CAS:
    <p>Eciskafusp alfa, a cis-targeted IL2v immunocytokine, acts on programmed cell death 1 (PDCD1, commonly known as PD-1), preferentially targeting antigen-specific</p>
    Pureza:98%
    Cor e Forma:Solid
  • IRAK4-IN-27


    <p>IRAK4-IN-27 (Compound 22) is a potent and selective IRAK4 inhibitor, demonstrating an IC50 of 8.7 nM.</p>
    Fórmula:C23H22N6O3
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:430.46
  • Avotaciclib hydrochloride


    <p>Avotaciclib hydrochloride, a CDK1 inhibitor, is the hydrochloride salt of Avotaciclib and exhibits potential therapeutic use in specific malignancies, including</p>
    Fórmula:C13H12ClN7O
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:317.73
  • Sterigmatocystine

    CAS:
    <p>Sterigmatocystine, a G1 phase and DNA synthesis inhibitor, curbs p21 and is a mycotoxin precursor from Aspergillus versicolor.</p>
    Fórmula:C18H12O6
    Pureza:98%
    Cor e Forma:Pale-Yellow Crystals Pale Yellow Solid
    Peso molecular:324.28
  • Annonacin

    CAS:
    <p>Annonacin is a cytotoxic acetogenin in Graviola leaf extract; it blocks mitochondrial complex and inhibits NKA/SERCA ATPase pumps.</p>
    Fórmula:C35H64O7
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:596.88
  • F1324 acetate


    <p>F1324 acetate is an efficient, high-affinity b-cell lymphoma inhibitor with IC50 of 1 nM.</p>
    Fórmula:C85H125N21O22S
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:1825.09
  • Episilvestrol

    CAS:
    <p>Episilvestrol is a derivative of silvestrol with eIF4A-targeted antitumor properties, found in Aglaia silvestris fruits and twigs.</p>
    Fórmula:C34H38O13
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:654.66
  • mTOR inhibitor-27


    <p>mTORinhibitor-27 (Compound 7e) is an inhibitor of mammalian target of rapamycin (mTOR) with an IC50 value of 5.47 μM. It can induce apoptosis in tumor cells and arrest the cell cycle in the S phase, thereby inhibiting cancer cell growth. mTORinhibitor-27 presents potential for research in cancer, including skin cancer.</p>
    Cor e Forma:Odour Solid
  • Deoxynyboquinone

    CAS:
    <p>Deoxynyboquinone is a potent inducer of cancer cell death with IC(50) values between 16 and 210 nM.</p>
    Fórmula:C15H12N2O4
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:284.27
  • Tubulysin B

    CAS:
    <p>Tubulysin B: a potent, cytotoxic microtubule-disrupting peptide from Archangium geophyra and Angiococcus disciformis.</p>
    Fórmula:C42H63N5O10S
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:830.04
  • Reveromycin A

    CAS:
    <p>Reveromycin A from Streptomyces sp. inhibits epidermal growth, tumors, and C. albicans; affects osteoclasts. IC50: 0.7-1.9 μg/ml; MIC: 2 μg/ml.</p>
    Fórmula:C36H52O11
    Cor e Forma:Solid
    Peso molecular:660.79
  • Emavusertib hydrochloride

    CAS:
    <p>Emavusertib (CA-4948) hydrochloride, a selective and potent IRAK4/FLT3 inhibitor, is designed for oral administration. It achieves an IC 50 of 57 nM against IRAK4 in a FRET kinase assay and demonstrates anti-tumor activity [1] [2] [3].</p>
    Fórmula:C24H26ClN7O5
    Cor e Forma:Solid
    Peso molecular:527.96
  • Leucettamol A

    CAS:
    <p>Leucettamol A, from Leucetta microraphis, blocks LTB4 receptor and prevents Ubc13-Uev1A complex formation.</p>
    Fórmula:C30H52N2O2
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:472.758
  • Ac-IEPD-AFC

    CAS:
    <p>Ac-IEPD-AFC (IEPD) is a fluorescent substrate for granzyme B and can be used to measure granzyme B activity.</p>
    Fórmula:C32H38F3N5O11
    Pureza:99.16%
    Cor e Forma:Solid
    Peso molecular:725.67
  • LY3415244


    <p>LY3415244 is a human bispecific antibody (bsAb) that targets B7-H1/PD-L1/CD274 and TIM-3/HAVCR2/CD366. This compound is applicable in the study of advanced solid tumors.</p>
    Cor e Forma:Odour Liquid
  • Ascochlorin

    CAS:
    <p>Ascochlorin, an isoprenoid antibiotic, inhibits STAT3 to combat tumors, induces apoptosis, and reduces inflammation.</p>
    Fórmula:C23H29ClO4
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:404.93
  • Ferroptosis-IN-14


    <p>Ferroptosis-IN-14 (compund 36) exhibits the most potent anti-ferroptotic activity with an EC50 value of 0.58 ± 0.02 μM, demonstrating excellent anti-ferroptotic efficacy, as well as stability in microsomes and plasma.</p>
    Cor e Forma:Odour Solid
  • Psalmotoxin 1

    CAS:
    <p>Psalmotoxin 1 is a potent and selective acid-sensing ion channel 1a (ASIC1a) blocker.</p>
    Fórmula:C200H312N62O57S6
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:4689.41