Apoptose
Os inibidores da apoptose são compostos que previnem ou retardam o processo de morte celular programada, conhecido como apoptose. Esses inibidores são vitais no estudo dos mecanismos de sobrevivência celular e são usados para investigar doenças onde a apoptose é desregulada, como câncer, distúrbios neurodegenerativos e doenças autoimunes. Ao modular a apoptose, esses inibidores podem ajudar no desenvolvimento de terapias destinadas a controlar a morte celular. Na CymitQuimica, oferecemos uma ampla seleção de inibidores da apoptose de alta qualidade para apoiar sua pesquisa em biologia celular, oncologia e áreas relacionadas.
Subcategorias de "Apoptose"
- ASK(6 produtos)
- BCL(11 produtos)
- Caspase(125 produtos)
- FOXO1(3 produtos)
- IAP(66 produtos)
- Mdm2(12 produtos)
- PD-1/PD-L1(125 produtos)
- PDK(9 produtos)
- PERK(25 produtos)
- Serina/treonina quinase(15 produtos)
- Survivina(13 produtos)
- TNF(92 produtos)
- c-RET(51 produtos)
- p53(62 produtos)
Exibir 6 mais subcategorias
Foram encontrados 5592 produtos de "Apoptose"
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Anticancer agent 55
CAS:<p>Potent anticancer agent inhibits cell growth, migration, induces apoptosis; promising for prostate, breast cancer studies.</p>Fórmula:C28H21Br2FN2O2Cor e Forma:SolidPeso molecular:596.294Nevanimibe
CAS:<p>Nevanimibe is an orally active and selective inhibitor of acyl-coenzyme A:cholesterol O-acyltransferase 1 (ACAT1) (EC50 of 9 nM).</p>Fórmula:C27H39N3OPureza:98%Cor e Forma:SolidPeso molecular:421.62AMG-548
CAS:<p>AMG-548, oral p38α inhibitor (Ki=0.5 nM), >1000x selectivity over p38γ/δ, blocks TNFα (IC50=3 nM), also inhibits Wnt/Casein kinase 1δ/ε.</p>Fórmula:C29H27N5OPureza:99.91%Cor e Forma:SolidPeso molecular:461.56PARP1-IN-10
CAS:<p>PARP1-IN-10 (12c) is a potent, non-toxic PARP1 inhibitor with a 50.62 nM IC50, enhancing TMZ effects and causing G2/M arrest and apoptosis.</p>Fórmula:C20H23N3O5Cor e Forma:SolidPeso molecular:385.41CHMFL-ABL/KIT-155
CAS:<p>CHMFL-ABL/KIT-155 is a highly potent and orally active type II ABL/c-KIT dual kinase inhibitor (IC50s: 46 nM/75 nM).</p>Fórmula:C33H38F3N5O3Pureza:98%Cor e Forma:SolidPeso molecular:609.68PD-1/PD-L1-IN-25
CAS:<p>"PD-1/PD-L1-IN-25 blocks PD-1/PD-L1 (IC50: 16.17 nM), boosting T-cell anti-tumor immunity, useful for cancer research."</p>Fórmula:C26H24ClN3O5Cor e Forma:SolidPeso molecular:493.94W146 TFA
CAS:<p>W146 TFA is a selective sphingosine-1-phosphate receptor 1 ( S1PR1 ) antagonist with an EC 50 value of 398 nM.</p>Fórmula:C18H28F3N2O6PCor e Forma:SolidPeso molecular:456.399Tubulin polymerization-IN-26
CAS:<p>Tubulin-IN-26 blocks microtubule formation at colchicine site; IC50 4.64μM; may help in lung cancer study.</p>Fórmula:C25H23N3O2Cor e Forma:SolidPeso molecular:397.47CDK8/19-IN-1
CAS:<p>CDK8/19-IN-1 is a selective and oral bioavailable CDK8/19 dual inhibitor (IC50s: 0.46 nM, 0.99 nM, and 270 nM for CDK8, CDK19, and CDK9).</p>Fórmula:C19H18N4O4S2Pureza:98%Cor e Forma:SolidPeso molecular:430.5GLUT4-IN-2
CAS:<p>GLUT4-IN-2, selective GLUT4 blocker; IC50: 6.8μM (GLUT4), 11.4μM (GLUT1). Induces apoptosis, G0/G1 arrest, has antitumor effects.</p>Fórmula:C17H11N3O4S2Pureza:99.90%Cor e Forma:SolidPeso molecular:385.42Antitumor agent-19
CAS:<p>Antitumor agent-19 is a modulator of tumor-associated macrophages with EC50s of 17.18 μM and 18.87 μM in the RAW 264.7 cells and the BMDM cells.</p>Fórmula:C24H21ClF3N5OPureza:98.95% - 99.38%Cor e Forma:SolidPeso molecular:487.9A-385358
CAS:<p>A-385358 is a selective Bcl-xL inhibitor with Kis of 0.80 nM for Bcl-xL and 67 nM for Bcl-2, respectively.</p>Fórmula:C32H41N5O5S2Pureza:99.97%Cor e Forma:SolidPeso molecular:639.83SMIP004
CAS:<p>SMIP004 is an SKP2 E3 ligase inhibitor. SMIP004 is a cancer cell-selective apoptosis inducer of human prostate cancer cells.</p>Fórmula:C13H19NOPureza:99.86%Cor e Forma:SolidPeso molecular:205.3PARP14 inhibitor H10
CAS:<p>PARP14 inhibitor H10 is a selective inhibitor against PARP14 with IC50 of 490 nM</p>Fórmula:C24H27N7O7SPureza:98%Cor e Forma:SolidPeso molecular:557.58Ferroptosis inducer-1
CAS:<p>Ferroptosis inducer-1 is a Ferroptosis inducer with antitumor potential .</p>Fórmula:C25H21ClN2O5Cor e Forma:SolidPeso molecular:464.9(E)-[6]-Dehydroparadol
CAS:<p>(E)-[6]-Dehydroparadol ((6)-Dehydroparadol), an oxidative metabolite of [6]-Shogaol, is a potent Nrf2 activator.</p>Fórmula:C17H24O3Pureza:99.85%Cor e Forma:SolidPeso molecular:276.37SCH529074
CAS:<p>SCH529074 is a selective activator of p53 (Ki = 1 μM) and can be used in studies about non-small-cell lung carcinoma.</p>Fórmula:C31H36Cl2N6Pureza:99.57%Cor e Forma:SolidPeso molecular:563.56Darinaparsin
CAS:<p>Darinaparsin, a dimethylated arsenic-glutathione compound, is cytotoxic to various cancer cells with diverse IC50 values and inhibits tumor growth in mice.</p>Fórmula:C12H22AsN3O6SCor e Forma:SolidPeso molecular:411.31EGFR-IN-88
CAS:<p>EGFR-IN-88 (Compound 4i), an EGFR inhibitor with an IC50 of 87 nM, exhibits cytotoxic effects on A549 cells at an IC50 of 3.902 μM and can induce cell apoptosis</p>Fórmula:C22H18Cl2N4O2SPureza:98%Cor e Forma:SolidPeso molecular:473.37MCL-1/BCL-2-IN-4
CAS:<p>MCL-1/BCL-2-IN-4 is a selective and potent Mcl-1 and Bcl-2 dual inhibitor.</p>Fórmula:C26H23BrN2O5SPureza:98%Cor e Forma:SolidPeso molecular:555.44CMLD012612
CAS:<p>CMLD012612 is a potent eukaryotic initiation factor 4A (eIF4A) inhibitor. It inhibits cell translation and is cytotoxic to NIH/3T3 cells (IC50: 2 nM).</p>Fórmula:C31H33N3O7Pureza:98%Cor e Forma:SolidPeso molecular:559.61BMS-1166 hydrochloride
CAS:<p>"Motixafortide blocks CXCR4 with 1 nM potency. BMS-1166 hinders PD-1/PD-L1, boosting T cell activation, IC50: 1.4 nM."</p>Fórmula:C36H34Cl2N2O7Pureza:98%Cor e Forma:SolidPeso molecular:677.57DCP-LA
CAS:<p>DCP-LA (FR236924), linoleic acid derivatives, selective and direct activation of PKCε.</p>Fórmula:C20H36O2Pureza:98%Cor e Forma:SolidPeso molecular:308.5PIK-C98
CAS:<p>PIK-C98 is an inhibitor of PI3K that acts by displaying potent preclinical activity against multiple myeloma.</p>Fórmula:C16H10Cl2N2OSPureza:98%Cor e Forma:SolidPeso molecular:349.23STAT3-IN-3
CAS:<p>STAT3-IN-3 is a potent and selective signal transducer inhibitor and transcription 3 (STAT3) activator.</p>Fórmula:C27H26BrN3O6SPureza:98%Cor e Forma:SolidPeso molecular:600.48RIPK1-IN-3
CAS:<p>RIPK1-IN-3 is a RIPK1 inhibitor, with anti-inflammatory proprieties.</p>Fórmula:C22H19F3N6O3Pureza:98%Cor e Forma:SolidPeso molecular:472.42MDM2-p53-IN-16
CAS:<p>MDM2-p53-IN-16 inhibits p53/MDM2 complex (IC 50 = 4.3 nM), triggers p53, causes GBM cell apoptosis, useful in cancer research.</p>Fórmula:C32H33N3O5Cor e Forma:SolidPeso molecular:539.62ORY-1001 free base
CAS:<p>ORY-1001: potent KDM1A inhibitor (IC50 <20nM), selective, affects THP-1 cell gene regulation and apoptosis, hinders MV(4;11) cell growth (EC50 <1nM).</p>Fórmula:C15H22N2Pureza:98%Cor e Forma:SolidPeso molecular:230.35T-3256336
CAS:<p>T-3256336 is an oral IAP blocker targeting cIAP-1, cIAP-2, and XIAP.</p>Fórmula:C31H45F2N5O5Pureza:98%Cor e Forma:SolidPeso molecular:605.72YLT205
CAS:<p>YLT205 is an inducer of apoptosis in human colorectal cells that acts by inhibiting tumor growth.</p>Fórmula:C16H12BrClN4O2S2Pureza:98%Cor e Forma:SolidPeso molecular:471.78MR2938
CAS:<p>MR2938: AChE inhibitor (IC50=5.04μM), reduces NO (IC50=3.29μM), blocks MAPK/JNK, NF-κB; for AD research.</p>Fórmula:C21H24N4O3Cor e Forma:SolidPeso molecular:380.44Necrostatin-7
CAS:<p>Necrostatin-7 (Necrostatin 7) is a necrotic apoptosis inhibitor with cardioprotective effects that inhibits RANK-NFATc1 signaling.</p>Fórmula:C16H10FN5OS2Pureza:98.71%Cor e Forma:SolidPeso molecular:371.41PD-1/PD-L1-IN-14
CAS:<p>PD-1/PD-L1-IN-14 (compound 17) is an inhibitor of PD-1/PD-L1 interaction (IC50=27.8 nM).</p>Fórmula:C24H24N4O2Cor e Forma:SolidPeso molecular:400.47NSC 146109 hydrochloride
CAS:<p>NSC 146109 hydrochloride is an activator of p53 targeting MDMX. NSC 146109 hydrochloride can be used for studies on breast cancer.</p>Fórmula:C17H17ClN2SPureza:99.28%Cor e Forma:SolidPeso molecular:316.85Tubulin/HDAC-IN-1
CAS:<p>Tubulin/HDAC-IN-1 is a dual inhibitor for tubulin & HDAC8, blocking polymerization & targeting HDAC8 (IC50: 150 nM), and induces cancer cell apoptosis.</p>Fórmula:C21H18N4O3Cor e Forma:SolidPeso molecular:374.39STK17A/B-IN-1
CAS:<p>STK17A/B-IN-1 (compound 9) is an orally active, potent, and selective inhibitor of STK17A/B, demonstrating an IC50 of 23 nM for STK17A. This compound is utilized in tumor research.</p>Fórmula:C26H27N7OCor e Forma:SolidPeso molecular:453.54Ki23057
CAS:<p>Ki23057, a FGFR2 inhibitor, boosts chemo effects in resistant gastric cancer, may work with SN38/PTX/VP16, enhancing apoptosis via ERCC1/p53 synergy.</p>Fórmula:C30H35N3O4Cor e Forma:SolidPeso molecular:501.62CYD-2-11
CAS:<p>CYD-2-11 is an effective and selective Bax agonist. It acts by targeting the structural pocket proximal to S184 in the C-terminal region of Bax.</p>Fórmula:C22H18N2O3Cor e Forma:SolidPeso molecular:358.39K145
CAS:<p>K145: Selective, oral SphK2 inhibitor, IC50 4.3 μM, Ki 6.4 μM, promotes cell apoptosis, strong antitumor effect, inactive against SphK1/other kinases.</p>Fórmula:C18H24N2O3SPureza:98%Cor e Forma:SolidPeso molecular:348.46Sanazole
CAS:<p>Sanazole is a 3-nitrotriazole cpd. It can affect the human cervical cancer cell line.</p>Fórmula:C7H11N5O4Cor e Forma:SolidPeso molecular:229.19RET-IN-8
CAS:<p>RET-IN-8 is an inhibitor of rearrangement kinase (RET) during transfection and can be used in cancer research.</p>Fórmula:C27H30N6O3Cor e Forma:SolidPeso molecular:486.57EGFR-IN-59
CAS:<p>EGFR-IN-59: EGFR inhibitor, IC50 = 190 nM, induces apoptosis, cytotoxic to A549 cells (IC50 = 8.62 μM) and WI38 cells (IC50 = 52.6 μM). Use: Various cancers.</p>Fórmula:C27H23N5O4SCor e Forma:SolidPeso molecular:513.57BMS-200
CAS:<p>BMS-200 is a potent PD-1/PD-L1 interaction inhibitor with IC50 of 80 nM.</p>Fórmula:C27H27F2NO6Cor e Forma:SolidPeso molecular:499.5LG190178
CAS:<p>LG190178, a vitamin D receptor (VDR) ligand, is a therapeutic agent used for the treatment of psoriasis, osteoporosis, and secondary hyperparathyroidism.</p>Fórmula:C28H42O5Cor e Forma:SolidPeso molecular:458.63TrxR inhibitor D9
CAS:<p>TrxR-IN-D9 is a novel inhibitor of thioredoxin reductase (TrxR).</p>Fórmula:C25H20AuOPSCor e Forma:SolidPeso molecular:596.43QTX125
CAS:<p>QTX125: potent, selective HDAC6 inhibitor with strong antitumor effects.</p>Fórmula:C23H19N3O5Cor e Forma:SolidPeso molecular:417.41Topoisomerase II inhibitor 7
CAS:<p>Topoisomerase II inhibitor 7 halts cell division and induces apoptosis, targeting topoisomerase II alpha with a 3.19 μM IC50.</p>Fórmula:C32H28BrN5O5SCor e Forma:SolidPeso molecular:674.56MMPSI
CAS:<p>MMPSI (Caspase-3/7 Inhibitor I) is a caspase 3 and caspase 7 inhibitor that inhibits ischemic injury in cardiomyocytes and can be used to study cardioprotection</p>Fórmula:C14H16N2O5SPureza:99.74%Cor e Forma:SolidPeso molecular:324.35ATX inhibitor 13
CAS:<p>ATX inhibitor 13: orally active, IC50 3.4 nM, halts RAW264.7 cells at G2, curbs growth/migration, prompts apoptosis, suppresses tumors.</p>Fórmula:C31H35Cl2N5O3Cor e Forma:SolidPeso molecular:596.55QM31
CAS:<p>QM31 is a selective Apaf-1 inhibitor(inbitita formation of the apoptosome with IC50 of 7.9μM).</p>Fórmula:C39H38Cl4N4O4Pureza:98%Cor e Forma:SolidPeso molecular:768.56Lemuteporfin
CAS:<p>Lemuteporfin is a light-activated photosensitizing agent confers cytotoxic upon light activation.reduce sebaceous gland volume in animal studies.</p>Fórmula:C44H48N4O10Pureza:97.14% - 99.44%Cor e Forma:SolidPeso molecular:792.87Nimustine
CAS:<p>Nimustine: treats brain tumors, used with other drugs or radiotherapy for neoplasms.</p>Fórmula:C9H13ClN6O2Cor e Forma:SolidPeso molecular:272.69Aurora kinase-IN-1
<p>Aurora kinase-IN-1: potent aurora kinase inhibitor, alters G1 cycle proteins, induces G1/S arrest and apoptosis, potential chemotherapy lead.</p>Fórmula:C30H25Br2N3O5Cor e Forma:SolidPeso molecular:667.34ARP 101
CAS:<p>ARP 101 is a selective matrix metalloproteinase-2 (MMP-2) inhibitor with anticancer activity.</p>Fórmula:C20H26N2O5SPureza:98.26%Cor e Forma:SolidPeso molecular:406.5Apoptotic agent-1
CAS:<p>Compound 8a is an apoptotic agent that boosts Fas receptor and Cyto C genes to fight cancer with low toxicity.</p>Fórmula:C12H6ClN5O2SCor e Forma:SolidPeso molecular:319.73Mutant p53 modulator-1
CAS:<p>Mutant p53 modulator-1 inhibits cancer with p53 mutations; see patent WO2021231474A1, compound 231B.</p>Fórmula:C27H32F4N8O2Cor e Forma:SolidPeso molecular:576.59CAY10506
CAS:<p>CAY10506, a hybrid lipoic acid-TZD, activates PPARγ to control glucose and lipid levels with an EC50 of 10 μM.</p>Fórmula:C20H26N2O4S3Cor e Forma:SolidPeso molecular:454.63VEGFR-2/BRAF-IN-1
<p>VEGFR-2/BRAF-IN-1 inhibits VEGFR-2, BRAF V600E & BRAF WT with IC50 of 49, 63 and 5 nM, triggers apoptosis, and halts G1/S cell cycle.</p>Fórmula:C26H20Cl2F3N5O3S2Cor e Forma:SolidPeso molecular:642.5DNL343
CAS:<p>DNL343 is an eIF2B activator that inhibits stress granule (SG) assembly induced by the C9ORF72 dipeptide repeat.</p>Fórmula:C20H19ClF3N3O4Pureza:99.96%Cor e Forma:SolidPeso molecular:457.83(S)-PERK-IN-5
CAS:<p>(S)-PERK-IN-5 is the S-enantiomer of PERK-IN-5. (S)-PERK-IN-5 is a PERK inhibitor (IC50: 0.101-0.250 μM).</p>Fórmula:C25H26F2N4O3Cor e Forma:SolidPeso molecular:468.5Docetaxel trihydrate
CAS:<p>Docetaxel trihydrate (RP-56976 Trihydrate) is an antineoplastic agent that has a unique mechanism of action as an inhibitor of cellular mitosis.</p>Fórmula:C43H59NO17Pureza:98.68% - >99.99%Cor e Forma:White Crystalline PowderPeso molecular:861.95HS56
CAS:<p>HS56: ATP-competitive Pim/DAPK3 inhibitor, Ki: DAPK3 (0.26μM), Pim-3 (0.208μM), Pim-1 (2.94μM), Pim-2 (>100μM), reduces hypertension in mice.</p>Fórmula:C13H8ClN5OSCor e Forma:SolidPeso molecular:317.75PHA-690509
CAS:<p>PHA-690509 is a cyclin-dependent kinase 2 inhibitor. It potentially for the treatment of cancer.</p>Fórmula:C17H21N3O2SPureza:98%Cor e Forma:SolidPeso molecular:331.43cRIPGBM
CAS:<p>cRIPGBM induces apoptosis in GBM CSCs by targeting RIPK2, with an EC50 of 68 nM in GBM-1 cells.</p>Fórmula:C26H20FN2O2Pureza:98%Cor e Forma:SolidPeso molecular:411.45DPBQ
CAS:<p>DPBQ (ZINC1620467) is a p53 activator.</p>Fórmula:C24H14N2O2Pureza:98.08%Cor e Forma:SolidPeso molecular:362.38Se-Methylselenocysteine hydrochloride
CAS:<p>Se-Methylselenocysteine hydrochloride, a precursor to Methylselenol, exhibits significant cancer chemopreventive and antioxidant activities.</p>Fórmula:C4H10ClNO2SePureza:98%Cor e Forma:SolidPeso molecular:218.54p53 Activator 5
CAS:<p>Potent p53 Activator 5, SC150 <0.05 mM, restores mutant p53 DNA binding, exhibits anti-tumor properties.</p>Fórmula:C29H32F6N4OCor e Forma:SolidPeso molecular:566.58Allethrin
CAS:<p>Allethrin induces oxidative stress, apoptosis and calcium release. Allethrin, a pyrethroid insecticide is a major mosquito repellent agent.</p>Fórmula:C19H26O3Pureza:99.52%Peso molecular:302.41Polyphyllin II
CAS:<p>Polyphyllin II (Chonglou Saponin II) has hemostasis, expectorant, bacteriostasis, anticytotoxic, anti-pregnancy kill sperm effects.</p>Fórmula:C44H70O16Pureza:99.92%Cor e Forma:SolidPeso molecular:855.02Erbstatin
CAS:<p>Erbstatin is a tyrosine-protein kinase inhibitor. When combined with foroxymithine, it has antineoplastic activity against L-1210 leukemia.</p>Fórmula:C9H9NO3Cor e Forma:SolidPeso molecular:179.17IST5-002
CAS:<p>IST5-002: Potent Stat5a/b blocker, IC50 1.5μM/3.5μM, targets prostate cancer & CML.</p>Fórmula:C17H20N5O7PPureza:99.36%Cor e Forma:SolidPeso molecular:437.34BI-0282
CAS:<p>BI-0282 (Compound 1) is a potent inhibitor of the MDM2-p53 interaction.</p>Fórmula:C30H23Cl2FN4O4Cor e Forma:SolidPeso molecular:593.43Z-LEVD-FMK
CAS:<p>Z-LEVD-FMK is a caspase-4 inhibitor with anti-cancer activity, capable of eliminating LPS-induced GCLC protein degradation.</p>Fórmula:C31H45FN4O10Cor e Forma:SolidPeso molecular:652.71PDE5-IN-3
CAS:<p>PDE5-IN-3: Inhibits PDE5 (1.57 nM), EGFR (5.827 μM), Wnt pathway (1286.96 ng/mL), induces apoptosis, and has antitumor effects.</p>Fórmula:C21H14BrN5O2Cor e Forma:SolidPeso molecular:448.27SD-36
CAS:<p>SD-36: Potent, selective PROTAC STAT3 degrader, Kd ~50 nM, effective on mutants, IC50=10 nM, strong anti-tumor effects, enables mouse tumor regression.</p>Fórmula:C59H62F2N9O12PPureza:98% - >99.99%Cor e Forma:SoildPeso molecular:1158.15PI3K/Akt/mTOR-IN-3
CAS:<p>PI3K/Akt/mTOR-IN-3 is a powerful inhibitor, halting MCF-7, HeLa, and HepG2 cell migration and triggering S phase arrest and apoptosis.</p>Fórmula:C34H51NO2Cor e Forma:SolidPeso molecular:505.77Bcl-2/Mcl-1-IN-2
CAS:<p>Bcl-2/Mcl-1-IN-2 is a Bcl-2 (Ki: 4.70 μM) and Mcl-1 (Ki: 0.88 μM) inhibitor.Bcl-2/Mcl-1-IN-2 can be used in cancer research.</p>Fórmula:C26H24ClNO3Cor e Forma:SolidPeso molecular:433.93Misetionamide
CAS:<p>Misetionamide: Oral oxathiazin-like, GAPDH inhibitor with anticancer properties for research use.</p>Fórmula:C3H7NO3SCor e Forma:SolidPeso molecular:137.16Xanthine oxidase-IN-6
<p>Xanthine oxidase-IN-6: potent oral mixed-type XOD inhibitor, IC50 1.37 µM, anti-hyperuricemia, renal protection.</p>Fórmula:C29H34N2O15Cor e Forma:SolidPeso molecular:650.58AV123
CAS:<p>AV123, a RIPK1 inhibitor, non-cytotoxic, IC50: 12.12 μM; blocks TNF-α necroptosis (EC50: 1.7 μM) not apoptosis; useful in necrosis-related disease studies.</p>Fórmula:C11H14N4O2Cor e Forma:SolidPeso molecular:234.25Prinomastat hydrochloride
CAS:<p>Prinomastat HCl, an oral MMP (1, 3, 9) inhibitor, IC50s: 79, 6.3, 5.0 nM, shows antitumor activity.</p>Fórmula:C18H22ClN3O5S2Pureza:98%Cor e Forma:SolidPeso molecular:459.97Anticancer agent 83
CAS:<p>Anticancer agent 83: potent, GI50 0.15 mM against LOX IMVI, reduces mitochondria potential, DNA damage, induces leukemia apoptosis.</p>Fórmula:C20H19N5OSCor e Forma:SolidPeso molecular:377.46Anticancer agent 32
CAS:<p>Compound 2g, an anticancer agent, disrupts cell cycle and induces apoptosis for cancer research.</p>Fórmula:C24H21F2N5OCor e Forma:SolidPeso molecular:433.45Epofolate
CAS:<p>Epofolate: folate receptor-targeted antimitotic, delivers epothilone to cancer cells, inhibits mitosis, may halt tumor growth. Check clinical trials.</p>Fórmula:C67H92N16O22S3Cor e Forma:SolidPeso molecular:1569.74c-Met-IN-14
CAS:<p>c-Met-IN-14: selective c-Met kinase inhibitor, IC50 2.89 nM, anticancer, stops G2/M phase, induces A549 cell apoptosis.</p>Fórmula:C34H38ClFN4O7SCor e Forma:SolidPeso molecular:701.2LLP-3
CAS:<p>Survivin inhibitor LLP-3 induces apoptosis in glioma cells by blocking Ran interaction; halts glioblastoma growth. IC50 = 31 μM.</p>Fórmula:C32H23ClN2O4Cor e Forma:SolidPeso molecular:534.99Antioxidant agent-5
CAS:<p>Antioxidant agent-5 (D-6) curbs oxLDL effects, ROS, NF-κB movement, apoptosis in VECs; boosts Nrf2/HO-1; protects endothelium.</p>Fórmula:C24H24N6OCor e Forma:SolidPeso molecular:412.49STAT5-IN-2
CAS:<p>STAT5-IN-2 is an inhibitor of STAT5 with antileukemic effects (EC50s: 9 μM and 5 μM in K562 and KU812 cells, respectively).</p>Fórmula:C26H27N3OPureza:99.55%Cor e Forma:SolidPeso molecular:397.51GL-331
CAS:<p>GL-331, a DNA topoisomerase II inhibitor, is used potentially for the treatment of small cell lung cancer and gastric cancer.</p>Fórmula:C27H24N2O9Cor e Forma:SolidPeso molecular:520.49HJC0416
CAS:<p>HJC0416 is a potent orally bioavailable signal transducer and activator of transcription 3 inhibitor.</p>Fórmula:C18H17ClN2O4SPureza:98%Cor e Forma:SolidPeso molecular:392.86ZT55
CAS:<p>ZT55: Oral JAK2 inhibitor, IC50: 0.031 μM, hinders JAK2 V617F HEL cell growth, induces apoptosis, arrests cell cycle, effective in mice HEL tumor studies.</p>Fórmula:C17H16N2O3Cor e Forma:SolidPeso molecular:296.32EGFR-IN-60
CAS:<p>EGFR-IN-60: oral anticancer drug, inhibits EGFR/JAK3, effective on H1975/A431 cells, promotes apoptosis.</p>Fórmula:C28H28Cl2N6OCor e Forma:SolidPeso molecular:535.47VRT-043198
CAS:<p>VRT-043198, a VX-765 metabolite, is a potent ICE/caspase-1 inhibitor, crossing the blood-brain barrier with K i of 0.8/0.6 nM.</p>Fórmula:C22H29ClN4O6Cor e Forma:SolidPeso molecular:480.94Pracinostat dihydrochloride
CAS:<p>Pracinostat dihydrochloride is a highly effective histone deacetylase (HDAC) inhibitor with IC₅₀ values ranging from 40 to 140 nM, utilized in cancer research. Additionally, it inhibits metallo-β-lactamase domain-containing protein 2 (MBLAC2) hydrolase activity with an EC₅₀ of less than 10 nM.</p>Fórmula:C20H32Cl2N4O2Cor e Forma:SolidPeso molecular:431.40Alteminostat
CAS:<p>Alteminostat is used as a histone deacetylase inhibitor and is an antineoplastic drug candidate.</p>Fórmula:C27H36N6O3Cor e Forma:SolidPeso molecular:492.61CMLD012072
CAS:<p>CMLD012072 is a potent eukaryotic initiation factor 4A (eIF4A) inhibitor with potent anti-neoplastic activity. It can induce RNA clamping of eIF4A1 and eIF4A2.</p>Fórmula:C32H32N2O7Pureza:98%Cor e Forma:SolidPeso molecular:556.61AG6033
CAS:<p>AG6033, a novel CRBN modulator, degrades GSPT1/IKZF1 and inhibits various tumors.</p>Fórmula:C30H23N5O4Cor e Forma:SolidPeso molecular:517.53Topoisomerase II inhibitor 10
CAS:<p>Topoisomerase II inhibitor 10 is a potent inhibitor of topoisomerase II (IC50: 7.45 μM).</p>Fórmula:C27H20N6O7SCor e Forma:SolidPeso molecular:572.55HDAC-IN-31
CAS:<p>HDAC-IN-31: Oral HDAC inhibitor; targets HDAC1, 2, 3; weak on HDAC8; potential in fighting lymphoma.</p>Fórmula:C25H24N4O2Cor e Forma:SolidPeso molecular:412.48RIPK1-IN-15
CAS:<p>RIPK1-IN-15 (Compound 2.5) is a potent RIPK1 inhibitor that has the potential in neurodegenerative, autoimmune, and inflammatory diseases research [1].</p>Fórmula:C19H19N3O2Cor e Forma:SolidPeso molecular:321.37MDM2-IN-1
CAS:<p>MDM2-IN-1 is a synthetic MDM2-p53 interaction (MDM2) inhibitor and contains the trans (D-)configuration.</p>Fórmula:C23H21Cl2FN2O3Cor e Forma:SolidPeso molecular:463.33Verrucarin J
CAS:<p>Verrucarin J, a Myrothecium fungus metabolite, triggers apoptosis in some cancer cells and fights Candida, Mucor, and JUNV (IC50: 1.2 ng/mL).</p>Fórmula:C27H32O8Cor e Forma:SolidPeso molecular:484.54PARP-1-IN-2
CAS:<p>PARP-1-IN-2 is a potent PARP1 inhibitor that crosses the blood-brain barrier (IC50: 149 nM).PARP-1-IN-2 showed significant antiproliferative activity against</p>Fórmula:C22H15Cl2N3O2Pureza:98.82%Cor e Forma:SolidPeso molecular:424.28DBIBB
CAS:<p>DBIBB: non-lipid LPA2 receptor agonist, treats acute radiation syndrome, aids in organic synthesis/drug research.</p>Fórmula:C23H20N2O6SPureza:98.49% - 99.1%Cor e Forma:SolidPeso molecular:452.48RSH-7
CAS:<p>RSH-7 is a potent dual inhibitor of BTK and FLT3, with IC50s of 47 and 12 nM, respectively.RSH-7 has antiproliferative and antitumor activities, inducing</p>Fórmula:C22H25FN8OPureza:98.31%Cor e Forma:SolidPeso molecular:436.49TRK-IN-23
CAS:<p>TRK-IN-23 (compound 24b) is a potent, orally active inhibitor of TRK with IC50s of 0.5 nM for TRKA, 9 nM for TRKC, 14 nM for TRKA G595R, 4.4 nM for TRKA F589L,</p>Fórmula:C20H17FN4O2Pureza:98%Cor e Forma:SolidPeso molecular:364.37Anticancer agent 72
CAS:<p>Compound 8c inhibits K+ channel and induces apoptosis, showing promise as an anticancer agent.</p>Fórmula:C20H19N7O2Cor e Forma:SolidPeso molecular:389.41Erasin
<p>Erasin is a STAT3 inhibitor induces apoptosis in various cancer cell lines (e.g., MDA-MB-231, HCC-827) and against Erlotinib-resistant cancer cells.</p>Fórmula:C20H19N3O3Cor e Forma:SolidPeso molecular:349.38MSN-50
CAS:<p>MSN-50, an inhibitor of Bax and Bak oligomerization, inhibits liposome permeabilization, prevents genotoxic cell death and promotes neuroprotection.</p>Fórmula:C36H38BrN3O6Cor e Forma:SolidPeso molecular:688.61YH-306
CAS:<p>YH-306 (TRV055 acetate ) is a modulator of the FAK signaling pathway that acts by suppressing colorectal tumor growth and metastasis.</p>Fórmula:C19H18N2O2Pureza:98.06%Cor e Forma:SolidPeso molecular:306.36MI-63
CAS:<p>MI-63 is a potent, specific, non-peptide inhibitor of the MDM2-p53 interaction.</p>Fórmula:C29H35Cl2FN4O3Cor e Forma:SolidPeso molecular:577.52AP1867
CAS:<p>AP1867 is a synthetic FKBP12F36V-directed ligand.</p>Fórmula:C38H47NO11Cor e Forma:SolidPeso molecular:693.78HMBPP triammonium
CAS:<p>HMBPP triammonium is a stimulator of gamma delta T cells.</p>Fórmula:C5H15NO8P2Cor e Forma:SolidPeso molecular:279.122LY5
CAS:<p>LY5 is an inhibitor of STAT3 that acts by inhibiting cell viability, cell migration, and angiogenesis in medulloblastoma cells.</p>Fórmula:C15H11N3O4SPureza:98%Cor e Forma:SolidPeso molecular:329.33p-nitro-Pifithrin-α
CAS:<p>p-nitro-Pifithrin-α is a cell-permeable analog of pifithrin-α, a potent p53 inhibitor.</p>Fórmula:C15H16BrN3O3SCor e Forma:SolidPeso molecular:398.27MCL-1/BCL-2-IN-3
CAS:<p>MCL-1/BCL-2-IN-3 is a selective and potent Mcl-1 and Bcl-2 dual inhibitor with IC50s of 5.95 and 4.78 μM, respectiely.</p>Fórmula:C27H25BrN2O5SCor e Forma:SolidPeso molecular:569.47S130
CAS:<p>S130 is a high affinity, selectiveATG4B (a major cysteine protease) inhibitor (IC50 of 3.24 μM).It suppresses autophagy flux.</p>Fórmula:C24H25N3O2Pureza:98%Cor e Forma:SolidPeso molecular:387.47PDMP (hydrochloride)
CAS:<p>PDMP, a glucosylceramide synthase inhibitor with 4 stereoisomers, acts at 0.8μM; D-threo enantiomer also blocks lactosylceramide synthesis.</p>Fórmula:C23H39ClN2O3Cor e Forma:SolidPeso molecular:427.03BIM-46174
CAS:<p>BIM-46174 has anticancer activity, inhibits the growth of a large number of human cancer cell lines, and induces caspase-3-dependent cancer cell apoptosis.</p>Fórmula:C22H30N4OSCor e Forma:SolidPeso molecular:398.57HBV-IN-23
CAS:<p>HBV-IN-23: HBV replication inhibitor, IC50 0.58μM, affects resistant strains, induces HepG2 apoptosis, anti-HCC.</p>Fórmula:C25H27N3O3SCor e Forma:SolidPeso molecular:449.57STAT3-IN-11
CAS:<p>STAT3-IN-11 is a STAT3 inhibitor.STAT3-IN-11 promotes apoptosis in cancer cells and is a candidate compound for the treatment of cancer.</p>Fórmula:C20H17NO4Pureza:98.3%Cor e Forma:SolidPeso molecular:335.35SMBA1
CAS:<p>SMBA1 is a Bax agonist with antitumor activity that can induce cell cycle arrest and apoptosis in malignant glioma cells.</p>Fórmula:C20H13NO3Pureza:99.2%Cor e Forma:SolidPeso molecular:315.32NSC260594
CAS:<p>NSC260594 is a chemical compound that promotes apoptosis by binding to the shallow groove of the Mcl-1 protein and suppressing its expression through down-</p>Fórmula:C29H24N6O3Cor e Forma:SolidPeso molecular:504.54RIPK1-IN-11
CAS:<p>RIPK1-IN-11, an oral RIPK1 blocker, Kd 9.2 nM, IC50 67 nM, prevents necrosis and inflammation in cells.</p>Fórmula:C23H24N4O4SCor e Forma:SolidPeso molecular:452.53Nec-3a
CAS:<p>Nec-3a, an analogue of Necrostatin-3, acts as a RIP1 inhibitor with an inhibition concentration (IC50) of 0.44 μM.</p>Fórmula:C21H18F4N2O4Cor e Forma:SolidPeso molecular:438.37UCB-6876
CAS:<p>UCB-6876 inhibits TNF signaling, stabilizes trimer asymmetry, shows concentration response, and is selective for TNFR1.</p>Fórmula:C17H18N2OCor e Forma:SolidPeso molecular:266.34Tubulin polymerization-IN-13
CAS:<p>Compound 4f inhibits tubulin polymerization (IC50: 0.37 μM), induces apoptosis, and has notable anti-cancer properties.</p>Fórmula:C20H21NO6Cor e Forma:SolidPeso molecular:371.38SMI-6860766
CAS:<p>SMI-6860766 is a CD40-Traf6 interactions blocker that acts by ameliorating the complications of diet-induced obesity in mice.</p>Fórmula:C15H11BrClNOPureza:98%Cor e Forma:SolidPeso molecular:336.61CU-3
CAS:<p>CU-3 inhibits DGKalpha, reducing cancer growth and boosting anti-cancer immunity.</p>Fórmula:C16H12N2O4S3Pureza:98%Cor e Forma:SolidPeso molecular:392.47TJ08
CAS:<p>TJ08 has anticancer properties and can effectively induce G1/S phase blockade while promoting apoptosis in a variety of cancer cells.</p>Fórmula:C22H16FN3O4Pureza:99.89%Cor e Forma:SolidPeso molecular:405.38Anticancer agent 164
CAS:<p>CML-IN-1, also known as compound 7 and compound 4, is a potent anticancer agent that demonstrates a strong induced-apoptosis effect in the human chronic myeloid</p>Fórmula:C21H23F3N8O2S2Pureza:98%Cor e Forma:SolidPeso molecular:540.58Telomerase-IN-4
CAS:<p>Telomerase-IN-4 is a potent inhibitor of telomerase with antiproliferative properties and induces apoptosis [1].</p>Fórmula:C21H18N4OS2Pureza:98%Cor e Forma:SolidPeso molecular:406.52Anticancer agent 57
CAS:<p>Anticancer agent 57 blocks TNBC cell growth with IC50: 6.43-8 μM, induces apoptosis, and shrinks tumors in mice.</p>Fórmula:C20H21Cl2NO2Cor e Forma:SolidPeso molecular:378.29Ac-IETD-CHO
CAS:<p>Ac-IETD-CHO is a potent, reversible inhibitor of granzyme B and caspase 8, which also impedes Fas-mediated apoptosis, hemorrhagic conditions, and liver failure.</p>Fórmula:C21H34N4O10Pureza:98%Cor e Forma:SolidPeso molecular:502.52Antiproliferative agent-32
CAS:<p>Antiproliferative agent-32 (Compound 1c) impedes phosphorylation within the PI3K/Akt/mTOR signaling pathway, restrains proliferation of Huh7 and SK-Hep-1 cells</p>Fórmula:C19H15NO2Pureza:98%Cor e Forma:SolidPeso molecular:289.33Telomerase-IN-5
CAS:<p>Telomerase-IN-5 is a potent inhibitor of telomerase with antiproliferative properties, and it induces apoptosis [1].</p>Fórmula:C22H20N4OS2Pureza:98%Cor e Forma:SolidPeso molecular:420.55AK301
CAS:<p>AK301 is a potent and selective inhibitor of tubulin polymerization and an effective sensitizer of cancer cells to apoptotic ligands (EC50 < 200 nM).</p>Fórmula:C19H21ClN2O2Pureza:99.27%Cor e Forma:SolidPeso molecular:344.84SZM-1209
CAS:<p>SZM-1209 is a potent and specific RIPK1 inhibitor with oral activity, displaying a dissociation constant (Kd) of 85 nM.</p>Fórmula:C31H29F5N4O5S2Pureza:98%Cor e Forma:SolidPeso molecular:696.71GDP366
CAS:<p>GDP366, induces cell growth inhibition, cellular senescence and mitotic catastrophe in human cancer cells. a dual inhibitor of survivin and Op18.</p>Fórmula:C20H17N5OSPureza:98.78% - 99.84%Cor e Forma:SolidPeso molecular:375.45Targapremir-210
CAS:<p>Targapremir-210 (TGP-210) is a miRNA-210 (miRNA-210) inhibitor that inhibits pre-miR-210 processing and induces apoptosis in breast cancer cells.</p>Fórmula:C32H36N10O2Pureza:98%Cor e Forma:SolidPeso molecular:592.69PI3Kδ/γ-IN-3
CAS:<p>PI3Kδ/γ-IN-3 (Compound 58) is an orally active dual inhibitor of PI3Kδ (IC50: 1 nM) and PI3Kγ (IC50: 16 nM).</p>Fórmula:C23H20ClN9OCor e Forma:SolidPeso molecular:473.92Undecylprodigiosin
CAS:<p>Undecylprodigiosin is a classical cytotoxic immunosuppressant, suppressing immune functions. It also inhibits DNA synthesis.</p>Fórmula:C25H35N3OCor e Forma:SolidPeso molecular:393.56NSC 107512
CAS:<p>NSC 107512, a sangivamycin-like molecule, inhibits CDK9, curbing myeloma growth and triggering cell death.</p>Fórmula:C12H16N6O5Cor e Forma:SolidPeso molecular:324.29Anticancer agent 76
CAS:<p>Compound CT2-3 is an anticancer agent that hinders growth, induces arrest, ROS, and apoptosis in NSCLC cells.</p>Fórmula:C32H33NO5SCor e Forma:SolidPeso molecular:543.67PD-1-IN-18
CAS:<p>PD-1-IN-18 is a PD1 inhibitor of signaling pathway, and acts as an immunomodulator.</p>Fórmula:C11H17N5O8Pureza:98%Cor e Forma:SolidPeso molecular:347.28NBI-42902
CAS:<p>NBI-42902 is a potent GnRH receptor antagonist (Ki=0.56 nm, Kd=0.19 nm), suppressing serum LH in macaques without causing histamine release.</p>Fórmula:C27H24F3N3O3Cor e Forma:SolidPeso molecular:495.49Anisperimus
CAS:<p>Anisperimus (LF 15-0195) is an immunosuppressant that prevents CNS autoimmunity by promoting the development of regulatory CD4 T cells expressing Foxp3.</p>Fórmula:C18H39N7O3Pureza:98.10%Cor e Forma:SolidPeso molecular:401.55c-Fms-IN-12
CAS:<p>c-Fms-IN-12 inhibits FMS/c-KIT, triggers A549 cell apoptosis, and has potential as a multi-cancer therapy.</p>Fórmula:C30H32N6O6Cor e Forma:SolidPeso molecular:572.61PI3K-IN-34
CAS:<p>PI3K-IN-34 targets PI3K-α/β/δ (IC50: 11.73/6.09/11.18 μM); potential leukemia research tool.</p>Fórmula:C23H22N6O3Cor e Forma:SolidPeso molecular:430.46pan-HER-IN-2
CAS:<p>pan-HER-IN-2 (Compound C6) is an orally active, reversible, broad-spectrum HER inhibitor that acts on EGFR (IC50: 0.72 nM), HER4 (IC50: 2.0 nM), EGFRT790M (IC50</p>Fórmula:C19H15BrClN5OCor e Forma:SolidPeso molecular:444.71BMS-566394
CAS:<p>BMS-566394 is a potent, exceptionally selective inhibitor of TNF-α converting enzyme (TACE).</p>Fórmula:C22H21F3N4O4Cor e Forma:SolidPeso molecular:462.42GL-V9
CAS:<p>GL-V9 is an AMPK activator, protecting against colitis-associated colorectal cancer by limiting NLRP3 inflammasome through autophagy.</p>Fórmula:C24H27NO5Cor e Forma:SolidPeso molecular:409.47hnRNPK-IN-1
CAS:<p>hnRNPK-IN-1 binds hnRNPK tightly (Kd 4.6-2.6 μM), disrupting c-myc transcription and inducing apoptosis in Hela cells.</p>Fórmula:C23H21N3O5Cor e Forma:SolidPeso molecular:419.43VII-31
CAS:<p>VII-31 is an activator of the NEDDylation pathway, capable of inducing apoptosis in MCF-7, PC-3, and MGC-803 cells.</p>Fórmula:C23H25NO5SCor e Forma:SolidPeso molecular:427.51p53 Activator 2
CAS:<p>p53 Activator 2 binds to DNA, breaks it, halts cell cycle at G2/M, triggers apoptosis, reduces Bcl-2/Bcl-xL, IC50: 1.73μM against MGC-803.</p>Fórmula:C20H21N5O2Cor e Forma:SolidPeso molecular:363.41CB-64D
CAS:<p>CB-64D is a sigma2R selective agonist which releases calcium in human neuroblastoma cells and produces cell death in tumor cell lines.</p>Fórmula:C22H23NO2Cor e Forma:SolidPeso molecular:333.42TPB15
CAS:<p>TPB15, an oral Hh inhibitor, blocks Smo activity, arrests cell cycle, induces apoptosis, and shows potent antitumor effects with low toxicity.</p>Fórmula:C18H9Cl4N5OCor e Forma:SolidPeso molecular:453.11BRD0476
CAS:<p>BRD0476 prevents pancreatic β-cell death by blocking IFN-γ-induced JAK2 & STAT1 without inhibiting JAK kinase activity.</p>Fórmula:C35H38N4O8SPureza:98%Cor e Forma:SolidPeso molecular:674.76AZD 1152 (hydrochloride)
CAS:<p>AZD 1152, an oral prodrug, becomes AZD 1152-HQPA in plasma, selectively inhibits Aurora kinase B (IC50=0.36 nM), and blocks tumor growth.</p>Fórmula:C26H33Cl2FN7O6PCor e Forma:SolidPeso molecular:660.47VU0424465
CAS:<p>VU0424465 is a mGlu5-selective allosteric agonist.</p>Fórmula:C19H19FN2O2Cor e Forma:SolidPeso molecular:326.36SCAL-266
CAS:<p>SCAL-266, a potent inhibitor of mitochondrial complex I (CI), exhibits an IC50 of 0.83 μM.</p>Fórmula:C27H28F3N5O2Pureza:98%Cor e Forma:SolidPeso molecular:511.54MM-102
CAS:<p>MM-102 (HMTase Inhibitor IX) is a potent inhibitor of WDR5/MLL interaction with IC50 of 2.4 nM and Ki of less than 1 nM in a WDR5 binding assay.Cost-effective and quality-assured.</p>Fórmula:C35H49F2N7O4Pureza:98.77% - 99.99%Cor e Forma:SolidPeso molecular:669.8CAY10747
CAS:<p>CAY10747, a celastrol derivative, inhibits Hsp90-Cdc37 interaction, decreases client proteins, and induces apoptosis in various cancer cells.</p>Fórmula:C42H48FNO6Cor e Forma:SolidPeso molecular:681.83Gemcitabine monophosphate
CAS:<p>R306465, a potent HDAC1/8 inhibitor, has broad antitumor effects (IC50: 30-300 nM) on solid and blood cancers.</p>Fórmula:C9H12F2N3O7PCor e Forma:SolidPeso molecular:343.18IQDMA
CAS:<p>IQDMA is an inhibitor of the transcription factor STAT5.</p>Fórmula:C19H20N4Cor e Forma:SolidPeso molecular:304.39PK9327
CAS:<p>PK9327 is a small-molecule stabilizer that targets cavity-creating p53 cancer mutations.</p>Fórmula:C21H22N2SCor e Forma:SolidPeso molecular:334.48Anticancer agent 50
CAS:<p>Anticancer agent 50 targets ABCB1 pump, has cytotoxic effects, alters cyclin D1/p53, and shows promise in T lymphoma research.</p>Fórmula:C30H32N2O4SeCor e Forma:SolidPeso molecular:563.55YL-939
<p>YL-939 is a potent inhibitor of ferroptosis, targeting the PHB2/ferritin/iron axis to impede this form of cell death.</p>Fórmula:C25H26N6OCor e Forma:SolidPeso molecular:426.51YC-137
CAS:<p>YC-137 inhibits BCL-2, triggers apoptosis in Bcl-2-high cells, and blocks its anti-apoptotic function.</p>Fórmula:C24H21N3O6S2Cor e Forma:SolidPeso molecular:511.57Anticancer agent 63
CAS:<p>Compound 3h fights various cancers; most effective on MCF-7 (IC50 3.4 μM). Triggers apoptosis; alters Bcl-2, IL-2, Caspase-3 levels, has antioxidant effects.</p>Fórmula:C17H24F3NOSeCor e Forma:SolidPeso molecular:394.33Caspase-3/7 activator 3
<p>Caspase-3/7 activator 3 triggers apoptosis with tumor selectivity and anti-proliferative effects.</p>Fórmula:C24H27NO5Cor e Forma:SolidPeso molecular:409.47Autophagy-IN-2
CAS:<p>Autophagy-IN-2 (7h) blocks autophagic flux, triggers cancer cell death, aids in triple-negative breast cancer study.</p>Fórmula:C17H19N5OCor e Forma:SolidPeso molecular:309.37OXPHOS-IN-1
CAS:<p>OXPHOS-IN-1 inhibits oxidative phosphorylation; halts MIA PaCa-2 (IC50: 2.34 μM) and BxPC-3 cells growth (IC50: 13.82 μM).</p>Fórmula:C19H29N3O6S2Cor e Forma:SolidPeso molecular:459.58HDAC-IN-42
CAS:<p>HDAC-IN-42, a potent HDAC inhibitor: IC50 - 0.19μM (HDAC1), 4.98μM (HDAC6); halts cancer cell growth, triggers apoptosis & G2/M arrest.</p>Fórmula:C20H15NO7Cor e Forma:SolidPeso molecular:381.34HLI 373
CAS:<p>HLI373: potent Hdm2 (ubiquitin ligase) inhibitor, induces apoptosis in tumor cells, has antimalarial properties.</p>Fórmula:C18H23N5O2Cor e Forma:SolidPeso molecular:341.41Caspase-9 Inhibitor III
CAS:<p>Caspase-9 Inhibitor III (Ac-LEHD-cmk) blocks caspase-9, protects against ischemic heart damage.</p>Fórmula:C24H35ClN6O9Cor e Forma:SolidPeso molecular:587.02PI3Kδ-IN-10
CAS:<p>PI3Kδ-IN-10 is a highly potent and orally active PI3Kδ inhibitor (IC50= 2 nM).</p>Fórmula:C19H16ClN9Cor e Forma:SolidPeso molecular:405.84Topoisomerase I inhibitor 3
CAS:<p>Topoisomerase I (Compound ZML-14) inhibitor 3 induces HepG2 cell apoptosis and arrests cell cycle at G2/M phase.</p>Fórmula:C18H14FNO3Cor e Forma:SolidPeso molecular:311.315HPP-33
CAS:<p>5HPP-33 is an microtubule-stabilizer with the properties of antiproliferative and antimitotic.</p>Fórmula:C20H21NO3Cor e Forma:SolidPeso molecular:323.39(S)-Elobixibat
CAS:<p>(S)-Elobixibat is the S-isomer of Elobixibat. It is an orally active inhibitor of Apical Sodium-Dependent Bile (IBAT) and can reduce LDL cholesterol, increase serum GLP-1, and promote colonic motility. This compound shows potential for treating metabolic syndrome and can be studied for constipation, dyslipidemia, non-alcoholic hepatitis, and liver tumors.</p>Fórmula:C36H45N3O7S2Cor e Forma:SolidPeso molecular:695.89TRAF-STOP inhibitor 6877002
CAS:<p>TRAF-STOP 6877002 inhibits CD40-TRAF6, curbing leukocyte recruitment and macrophage activation/proliferation in plaques.</p>Fórmula:C17H17NOPureza:99.76%Cor e Forma:SolidPeso molecular:251.32BP-1-108
CAS:<p>BP-1-108 is a potent and selective STAT5 inhibitor.</p>Fórmula:C32H38N2O6SCor e Forma:SolidPeso molecular:578.72Apoptosis inducer 6
CAS:<p>Apoptosis inducer 6 is an anticancer agent with broad-spectrum anticancer activity that induces apoptosis, which triggers cell death.</p>Fórmula:C27H26N4O3SCor e Forma:SolidPeso molecular:486.59Bozepinib
CAS:<p>Bozepinib is an antitumor compound that acts by inducing PKR-mediated apoptosis and synergizing with IFN.</p>Fórmula:C20H14Cl2N6O5SPureza:98%Cor e Forma:SolidPeso molecular:521.33GZD856
CAS:<p>GZD856 is an orally bioavailable PDGFRα/β inhibitor (IC50s: 68.6 and 136.6 nM) with anti-lung cancer activities.</p>Fórmula:C29H27F3N6OPureza:98%Cor e Forma:SolidPeso molecular:532.56Tubulin polymerization-IN-22
CAS:<p>Tubulin polymerization-IN-22 inhibits tubulin (IC50=8.1μM), blocks G2/M phase, and triggers apoptosis.</p>Fórmula:C19H16O4Cor e Forma:SolidPeso molecular:308.33EP12
CAS:<p>EP12, a c-Myc inhibitor and G4 stabilizer, induces apoptosis and DNA damage in multiple myeloma cells while obstructing P65/P50 nuclear translocation by</p>Fórmula:C26H22FN3O2Pureza:98%Cor e Forma:SolidPeso molecular:427.47LG308
CAS:<p>LG308, a synthetic compound, has anti-tumor properties, inducing apoptosis and mitotic arrest, thereby suppressing prostate cancer growth.</p>Fórmula:C19H17FN2OCor e Forma:SolidPeso molecular:308.35Anticancer agent 147
CAS:<p>Compound 6j (Anticancer agent 147), a sophoridine derivative and ferroptosis inducer, promotes intracellular accumulation of Fe2+, reactive oxygen species (ROS</p>Fórmula:C32H40BrN3O2Pureza:98%Cor e Forma:SolidPeso molecular:578.58SAHA-OH
CAS:<p>SAHA-OH selectively inhibits HDAC6 (IC50 = 23 nM) with 10-47x preference over HDACs 1, 2, 3, 8, and reduces inflammation and macrophage apoptosis.</p>Fórmula:C15H22N2O4Pureza:98%Cor e Forma:SolidPeso molecular:294.35Mcl-1 inhibitor 10
CAS:<p>Mcl-1 inhibitor10 (compound 43) is a relatively potent MCL-1 inhibitor with an IC50 of 0.67 μM. It interacts with a specific binding site on the MCL-1 protein, disrupting its pro-survival signals and inducing apoptosis in cancer cells. This compound is useful for research on MCL-1-dependent cancers.</p>Fórmula:C21H15F3O4Cor e Forma:SolidPeso molecular:388.34Butyrolactone I
CAS:<p>Butyrolactone I (Olomoucin) inhibits CDKs, blocks cdc2 kinases, and shows antitumor activity in lung and prostate cancers.</p>Fórmula:C24H24O7Pureza:98%Cor e Forma:SolidPeso molecular:424.44iMAC2
CAS:<p>iMAC2, a potent MAC (Membrane Attack Complex) inhibitor, exhibits an IC50 of 28 nM and an LD50 of 15,000 nM, demonstrating significant efficacy in inhibiting</p>Fórmula:C19H20Br2FN3Cor e Forma:SolidPeso molecular:469.19TNF-α-IN-18
CAS:<p>TNF-α-IN-18 is a small molecule TNF-α inhibitor that blocks NF-κB translocation, alleviates sepsis in models, and protects against rheumatoid arthritis in mice.</p>Fórmula:C16H7ClF2O4Pureza:99.77%Cor e Forma:SolidPeso molecular:336.67MMP2-IN-1
CAS:<p>MMP2-IN-1, an MMP2 inhibitor (IC50 = 6.8μM), halts growth and induces apoptosis in some cancers.</p>Fórmula:C15H13NO5SCor e Forma:SolidPeso molecular:319.33IHMT-TRK-284
CAS:<p>IHMT-TRK-284: Oral type II TRK inhibitor; targets TRKA, TRKB, TRKC (IC50s: 10.5, 0.7, 2.6 nM); selective and anti-tumor effective.</p>Fórmula:C25H27N7OSCor e Forma:SolidPeso molecular:473.59CN128 hydrochloride
CAS:<p>CN128 hydrochloride is an oral, selective hydroxypyridone iron chelator for β-thalassemia research.</p>Fórmula:C15H18ClNO3Cor e Forma:SolidPeso molecular:295.76Anti-inflammatory agent 47
CAS:<p>Flo8, an anti-inflammatory and antioxidant agent, effectively suppresses the release of reactive oxygen species (ROS) and nitric oxide (NO) while inhibiting</p>Fórmula:C25H18N2O3Pureza:98%Cor e Forma:SolidPeso molecular:394.42DMH2
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