Apoptose
Os inibidores da apoptose são compostos que previnem ou retardam o processo de morte celular programada, conhecido como apoptose. Esses inibidores são vitais no estudo dos mecanismos de sobrevivência celular e são usados para investigar doenças onde a apoptose é desregulada, como câncer, distúrbios neurodegenerativos e doenças autoimunes. Ao modular a apoptose, esses inibidores podem ajudar no desenvolvimento de terapias destinadas a controlar a morte celular. Na CymitQuimica, oferecemos uma ampla seleção de inibidores da apoptose de alta qualidade para apoiar sua pesquisa em biologia celular, oncologia e áreas relacionadas.
Subcategorias de "Apoptose"
- ASK(6 produtos)
- BCL(11 produtos)
- Caspase(125 produtos)
- FOXO1(3 produtos)
- IAP(66 produtos)
- Mdm2(12 produtos)
- PD-1/PD-L1(125 produtos)
- PDK(9 produtos)
- PERK(25 produtos)
- Serina/treonina quinase(15 produtos)
- Survivina(13 produtos)
- TNF(92 produtos)
- c-RET(51 produtos)
- p53(62 produtos)
Exibir 6 mais subcategorias
Foram encontrados 5592 produtos de "Apoptose"
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Valinomycin
CAS:<p>Valinomycin (NSC-122023) is a cyclic depsipeptide antibiotic and a potassium-specific ionophore.Valinomycin induces PINK1 activation and promotes Parkin</p>Fórmula:C54H90N6O18Pureza:95.37% - 97.16%Cor e Forma:White SolidPeso molecular:1111.32Boc-Asp(OMe)-fluoromethyl ketone
CAS:<p>Boc-Asp(OMe)-FMK is a broad-spectrum caspase inhibitor that blocks Fas-mediated processes without affecting IL-8 chemotaxis.</p>Fórmula:C11H18FNO5Pureza:≥98%Cor e Forma:SolidPeso molecular:263.26LYN-1604
CAS:<p>LYN-1604 is a novel activator of ULK1, inducing cell death involved in ATF3, RAD21, and caspase3, accompanied by autophagy and apoptosis.</p>Fórmula:C33H43Cl2N3O2Pureza:98%Cor e Forma:SolidPeso molecular:584.62BMS-202
CAS:<p>BMS-202 (PD1-PDL1 inhibitor 2) is an inhibitor of the PD-1 (Programmed death- 1) /PD-Ll (Programmed death-ligand 1) protein/protein interaction.</p>Fórmula:C25H29N3O3Pureza:97.92% - 99.66%Cor e Forma:SolidPeso molecular:419.52SP2509
CAS:<p>SP2509 is a specific histone demethylase LSD1 inhibitor(IC50 =13 nM).</p>Fórmula:C19H20ClN3O5SPureza:98.82% - 99.53%Cor e Forma:SolidPeso molecular:437.9PU02
CAS:<p>PU02 (6-[(1-Naphthalenylmethyl)thio]-9H-purine) is a potent and selective antagonist of 5-HT3 receptor.</p>Fórmula:C16H12N4SPureza:99.35%Cor e Forma:SolidPeso molecular:292.36Kaempferol
CAS:<p>Kaempferol (Robigenin) is a natural flavonoid and an inverse agonist of ERRα and ERRγ.</p>Fórmula:C15H10O6Pureza:98% - 99.41%Cor e Forma:Yellow Needles From Alcohol And Water SolidPeso molecular:286.24physalin F
CAS:<p>Physalin F is a natural blocker of CaV2.3 (R-type) and CaV2.2 (N-type) voltage-gated calcium channels.Cost-effective and quality-assured.</p>Fórmula:C28H30O10Pureza:99.5% - 99.61%Cor e Forma:SolidPeso molecular:526.53Apitolisib
CAS:<p>Apitolisib (RG 7422) is a PI3K inhibitor, used in cancer trials, targeting PI3Kα, β, δ, γ (IC50= 5, 27, 7, 14 nM).</p>Fórmula:C23H30N8O3SPureza:98.28% - 99.64%Cor e Forma:SolidPeso molecular:498.6Kobe0065
CAS:<p>Kobe0065: novel small-molecule, inhibits Ras–Raf, Ki=46±13 μM, blocks H-Ras·GTP/c-Raf-1 RBD binding.</p>Fórmula:C15H11ClF3N5O4SPureza:98% - >99.99%Cor e Forma:SolidPeso molecular:449.79α-Mangostin
CAS:<p>alpha-Mangostin (Mangostin) is a natural xanthonoid, a type of organic compound isolated from various parts of the mangosteen tree.</p>Fórmula:C24H26O6Pureza:98.22% - 99.49%Cor e Forma:Yellow PowderPeso molecular:410.46DPN
CAS:<p>DPN (Diarylpropionitrile) is an selective agonist of estrogen receptor β (ERβ) .</p>Fórmula:C15H13NO2Pureza:99.01%Cor e Forma:Off-White SolidPeso molecular:239.27Selumetinib
CAS:<p>Selumetinib (AZD6244) is a selectivity and non-ATP-competitive MEK1/2 inhibitor. Selumetinib has antitumor activity. Cost-effective and quality-assured.</p>Fórmula:C17H15BrClFN4O3Pureza:98.1% - 99.90%Cor e Forma:White Or Pale White SolidPeso molecular:457.68SM-164
CAS:<p>SM-164 binds to XIAP protein containing both the BIR2 and BIR3 domains (IC50: 1.39 nM). It acts as an extremely potent antagonist of XIAP.</p>Fórmula:C62H84N14O6Pureza:98.53% - 99.92%Cor e Forma:SolidPeso molecular:1121.42FTI-277 hydrochloride
CAS:<p>FTI-277 HCl: potent FTase inhibitor, IC50 500 pM, 100x more selective than GGTase I.</p>Fórmula:C22H30ClN3O3S2Pureza:97.57% - 97.61%Cor e Forma:SolidPeso molecular:484.07CID5721353
CAS:<p>CID5721353 disrupts BCL6/corepressor complexes, binds critical BTB groove site in vitro/vivo.</p>Fórmula:C15H9BrN2O6S2Pureza:98.90%Cor e Forma:SolidPeso molecular:457.28Nutlin-3a
CAS:<p>Nutlin-3a is the active enantiomer of Nutlin-3, an MDM2 antagonist that inhibits MDM2-p53 interaction. Nutlin-3a has antitumor activity. Cost-effective and quality-assured.</p>Fórmula:C30H30Cl2N4O4Pureza:95.62% - 99.71%Cor e Forma:SolidPeso molecular:581.49Apoptozole
CAS:<p>Apoptozole (Apoptosis Activator VII) is an inhibitor of the ATPase domain of Hsc70 and Hsp70, and can induce apoptosis.</p>Fórmula:C33H25F6N3O3Pureza:99.75%Cor e Forma:SolidPeso molecular:625.56Quisinostat dihydrochloride
CAS:<p>Quisinostat dihydrochloride (JNJ26854165(Quisinostat) 2HCl) 是一种有口服活性，高效的 pan-HDAC 抑制剂，具有广泛的抗肿瘤活性。它对 HDAC1、HDAC2、HDAC4、HDAC10和HDAC11 的IC50值分别为 0.11 nM、0.33 nM、0.64 nM、0.46 nM 和 0.37 nM。</p>Fórmula:C21H28Cl2N6O2Pureza:97.13%Cor e Forma:SolidPeso molecular:467.39Atopaxar hydrochloride
CAS:<p>Atopaxar hydrochloride is used in the Treatment of Cardiovascular Disorders.</p>Fórmula:C29H39ClFN3O5Cor e Forma:SolidPeso molecular:564.1R1530
CAS:<p>R1530 is a multikinase inhibitor with antineoplastic and antiangiogenesis activities.</p>Fórmula:C18H14ClFN4OPureza:98.422%Cor e Forma:SolidPeso molecular:356.78Y-27632
CAS:<p>Y-27632 (Y-27632) is an orally potent, ATP-competitive inhibitor of ROCK-I and ROCK-II.</p>Fórmula:C14H21N3OPureza:99.53% - 99.87%Cor e Forma:SolidPeso molecular:247.34Calpeptin
CAS:<p>Calpeptin is a potent, cell-permeable calpain inhibitor.</p>Fórmula:C20H30N2O4Pureza:97.06% - 98.33%Cor e Forma:White To Off-White PowderPeso molecular:362.463-Bromopyruvic acid
CAS:<p>3-Bromopyruvic acid (Hexokinase II Inhibitor II, 3-BP) is a hexokinase II inhibitor with Ki of 2.4 mM for glycolysis/hexokinase inhibition.</p>Fórmula:C3H3BrO3Pureza:95% - 99.644%Cor e Forma:White To Pale Yellow Crystalline PowderPeso molecular:166.96Fangchinoline
CAS:<p>Fangchinoline (Tetrandrine B) is extracted from Stephania tetrandra S. Moore.</p>Fórmula:C37H40N2O6Pureza:99.86% - >99.99%Cor e Forma:SolidPeso molecular:608.72Lexibulin
CAS:<p>Lexibulin (CYT-997)(CYT-997) is a potent tubulin polymerization inhibitor (IC50: 10-100 nM, in Y cell lines).</p>Fórmula:C24H30N6O2Pureza:98.87%Cor e Forma:SolidPeso molecular:434.53Cucurbitacin IIb
CAS:<p>Cucurbitacin IIb is an active ingredient in Hemsleyadine, used to treat dysentery and other infections; it has anti-inflammatory effects.</p>Fórmula:C30H48O7Pureza:98.66% - >99.99%Cor e Forma:SolidPeso molecular:520.7Poncirin
CAS:<p>Poncirin inhibits human gastric cancer cell growth and prevents fat formation while boosting bone density and improving structure in osteoporosis mice.</p>Fórmula:C28H34O14Pureza:99.89% - 99.92%Cor e Forma:SolidPeso molecular:594.56Entinostat
CAS:<p>Entinostat (MS-275) is an HDAC class I with oral activity. Entinostat has antitumor activity. Cost-effective and quality-assured.</p>Fórmula:C21H20N4O3Pureza:98% - 99.74%Cor e Forma:SolidPeso molecular:376.41Ligustilide
CAS:<p>3-Butylidene-4,5-dihydrophthalide is an effective constituent extracted from Angelica sinensis.</p>Fórmula:C12H14O2Pureza:96.03% - 98.14%Cor e Forma:Yellow Brown PowderPeso molecular:190.24Dioscin
CAS:<p>Dioscin (Collettiside III) is a saponin with antitumor activities.</p>Fórmula:C45H72O16Pureza:99.85% - 99.87%Cor e Forma:SolidPeso molecular:869.04JIB-04
CAS:<p>JIB-04 (NSC 693627) is a pan-selective Jumonji histone demethylase inhibitor.</p>Fórmula:C17H13ClN4Pureza:98.02% - 98.87%Cor e Forma:SolidPeso molecular:308.76Tebufenozide
CAS:<p>Tebufenozide is a novel nonsteroidal ecdysone agonist. It shows good efficacy and playing an increasingly important role in the control of Lepidopteran pests.</p>Fórmula:C22H28N2O2Pureza:98%Cor e Forma:SolidPeso molecular:352.47Y-320
CAS:<p>Y-320 is a new phenylpyrazoleanilide immunomodulator.</p>Fórmula:C27H29ClN6O2Pureza:98% - 99.64%Cor e Forma:SolidPeso molecular:505.01PIK-75 hydrochloride
CAS:<p>PIK-75 hydrochloride (PIK-75 HCl) is a p110α inhibitor, isoform-specific mutants at Ser773, and potently inhibits DNA-PK with IC50 of 2 nM in cell-free assay.</p>Fórmula:C16H14BrN5O4S·HClPureza:97.82%Cor e Forma:SolidPeso molecular:488.745-Aminolevulinic acid hydrochloride
CAS:<p>5-Aminolevulinic acid hydrochloride (5-ALA) serves as an intermediate in the body's heme biosynthesis and is the universal precursor of tetrapyrroles.</p>Fórmula:C5H10ClNO3Pureza:98% - 99.97%Cor e Forma:White To Pale Yellow Crystals OrPeso molecular:167.59Pulsatilla saponin D
CAS:<p>Pulsatilla saponin D (Hederacolchiside A) may prevent cancer, hindering cancer cell growth through cell cycle arrest and apoptosis.</p>Fórmula:C47H76O17Pureza:99.55%Cor e Forma:SolidPeso molecular:913.1Fludarabine Phosphate
CAS:<p>Fludarabine Phosphate (NSC 312887 Phosphate) is a fluorinated nucleotide antimetabolite analog of the antiviral agent vidarabine with antineoplastic activity.</p>Fórmula:C10H13FN5O7PPureza:99.25% - 99.78%Cor e Forma:SolidPeso molecular:365.21L-Theanine
CAS:<p>L-Theanine, a unique amino acid from Camellia sinensis tea, induces relaxation without drowsiness.</p>Fórmula:C7H14N2O3Pureza:99.31% - 99.38%Cor e Forma:White Crystals From Ethanol + Water White Crystalline SolidPeso molecular:174.2Glaucocalyxin A
CAS:<p>Glaucocalyxin A improves drug delivery, activates apoptosis, inhibits cell growth, with potential as an antiplatelet agent.</p>Fórmula:C20H28O4Pureza:99.55% - 99.80%Cor e Forma:SolidPeso molecular:332.43Phthalazinone pyrazole
CAS:<p>Phthalazinone pyrazole: a potent, selective oral Aurora-A kinase inhibitor, overexpressed in tumors with oncogenic activity.</p>Fórmula:C18H15N5OPureza:97.03%Cor e Forma:SolidPeso molecular:317.34Pyroxamide
CAS:<p>Pyroxamide is an histone deacetylases (HDACs) inhibitor with antineoplastic properties ( HDAC1;IC50: 0.1-0.2 μM).</p>Fórmula:C13H19N3O3Pureza:98.46%Cor e Forma:SolidPeso molecular:265.31Pinoresinol
CAS:<p>Pinoresinol ((+)-Pinoresinol) has antiinflammatory, hepatoprotective, and fungicidal activities, it can protect pial microcirculation from I-reperfusion injury</p>Fórmula:C20H22O6Pureza:98.67%Cor e Forma:SolidPeso molecular:358.391-(4-Chloro-3-(trifluoromethyl)phenyl)-3-(4-(4-cyanophenoxy)phenyl)urea
CAS:<p>SC-1 is a a derivative of the multiple tyrosine kinase inhibitor sorafenib.</p>Fórmula:C21H13ClF3N3O2Pureza:99.41%Cor e Forma:SolidPeso molecular:431.82-Deoxy-D-glucose
CAS:<p>2-Deoxy-D-glucose (2-DG) is an analog of glucose, an inhibitor of glycolysis.</p>Fórmula:C6H12O5Pureza:99.31% - ≥98%Cor e Forma:White PowderPeso molecular:164.16BX-912
CAS:<p>BX-912 inhibits PDK1 with IC50 of 12 nM; over 10x more selective versus C-Kit, EGFR, PKA, PKC.</p>Fórmula:C20H23BrN8OPureza:98.29% - 99.34%Cor e Forma:SolidPeso molecular:471.35Supinoxin
CAS:<p>Supinoxin (RX-5902) is an oral anti-cancer drug targeting p68 RNA helicase, inducing apoptosis in TNBC cells (IC50: 10-20nM).</p>Fórmula:C22H24FN5O4Pureza:99.83% - 99.95%Cor e Forma:SolidPeso molecular:441.46GDC-0152
CAS:<p>GDC-0152 is a potent inhibitor of IAPs.</p>Fórmula:C25H34N6O3SPureza:97.18% - 99.32%Cor e Forma:SolidPeso molecular:498.64CCT128930 hydrochloride
CAS:<p>CCT128930 hydrochloride: Potent AKT inhibitor (IC50=6 nM), 28x selective over PKA, 20x over p70S6K, induces cell cycle arrest & DNA damage.</p>Fórmula:C18H21Cl2N5Pureza:98.55%Cor e Forma:SolidPeso molecular:378.3Lobaplatin
CAS:<p>Lobaplatin (D-19466) (D-19466) is a diastereometric mixture of platinum(II) complexe.</p>Fórmula:C9H18N2O3PtPureza:98.00%Cor e Forma:SolidPeso molecular:397.33
