Ferroptose
A ferroptose é uma forma de morte celular regulada caracterizada pelo acúmulo de peróxidos lipídicos e estresse oxidativo dependente de ferro. Ao contrário da apoptose, a ferroptose não é impulsionada por caspases, mas pelo fracasso das defesas antioxidantes celulares, levando à morte celular. Inibidores e indutores de ferroptose são críticos para estudar essa via única de morte celular, que está implicada em várias doenças, incluindo câncer, neurodegeneração e lesão por isquemia-reperfusão. Na CymitQuimica, oferecemos uma ampla gama de moduladores de ferroptose de alta qualidade para apoiar sua pesquisa em mecanismos de morte celular, estresse oxidativo e patologia de doenças.
Foram encontrados 215 produtos de "Ferroptose"
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Ferroptosis-IN-16
<p>Ferroptosis-IN-16 (Compound 13l) acts as a specific inhibitor of ferroptosis, demonstrating EC50 values of 0.7 nM in ES-2 cells and 0.9 nM in LX-2 cells. It effectively alleviates acute liver injury induced by Acetaminophen in mouse models and shows excellent metabolic stability in mouse liver microsomes.</p>Fórmula:C26H23N5OCor e Forma:SolidPeso molecular:421.49W1131 TFA
<p>W1131 TFA is a STAT3 inhibitor and ferroptosis inducer that regulates the IL6-JAK-STAT3 and ferroptosis pathways,gastric cancer.</p>Fórmula:C25H20F3N5O6Pureza:98.1%Cor e Forma:SolidPeso molecular:543.45PRLX-93936 HCL
CAS:<p>PRLX-93936 HCL is an analog of erastin and demonstrated synergistic effects against non-small cell lung cancer (NSCLC) cells with cisplatin.</p>Fórmula:C21H26Cl2N4O2Pureza:98.4% - 99.94%Cor e Forma:SolidPeso molecular:437.3784-B10
CAS:<p>84-B10 provides protection in cisplatin-induced acute kidney injury, reversing lipid peroxidation accumulation and downregulation of key ferroptosis inhibitors.</p>Fórmula:C25H22F3NO5Pureza:99.76%Cor e Forma:SolidPeso molecular:473.44CuATSM
CAS:<p>Cu/Zn-SOD1 enzyme scavenges radicals; mutations cause ALS. Cu-ATSM, crossing blood-brain barrier, targets hypoxic tissue, may aid ALS mice.</p>Fórmula:C8H14CuN6S2Cor e Forma:SolidPeso molecular:321.92Idebenone
CAS:Fórmula:C19H30O5Pureza:>98.0%(T)(HPLC)Cor e Forma:Light yellow to Brown powder to crystalPeso molecular:338.44CuATSP
CAS:<p>CuATSP is a potent free radical trapping antioxidant (RTA) and ferroptosis inhibitor inhibit lipid peroxidation, for (ALS) and Parkinson's disease.</p>Fórmula:C18H18CuN6S2Pureza:97.09%Cor e Forma:SolidPeso molecular:446.05Cerivastatin sodium
CAS:<p>Cerivastatin sodium (BAY W 6228 sodium) is an HMG-CoA reductase inhibitor with lipid-lowering activity that reduces LDL cholesterol levels.</p>Fórmula:C26H33FNNaO5Pureza:98.50% - 99.67%Cor e Forma:SolidPeso molecular:481.53CCW16
CAS:<p>CCW16 is a covalent E3 ubiquitin ligase RNF4 ligand, cysteine reactivity, inducing ferroptosis in AML cells by activating ROS signalling.</p>Fórmula:C22H20ClNO3Pureza:97%Cor e Forma:SolidPeso molecular:381.85Chrysosplenetin
CAS:<p>Chrysosplenetin is a metabolic inhibitor of artemisinin.</p>Fórmula:C19H18O8Pureza:97.43% - 98.4%Cor e Forma:SolidPeso molecular:374.34L-Glutamic acid monosodium salt
CAS:<p>L-Glutamic acid monosodium salt (MSG) (Monosodium glutamate) is an activator of mGlu1 receptor.</p>Fórmula:C5H8NO4·NaPureza:99.93%Cor e Forma:White Solid CrystallinePeso molecular:169.11Piperlongumine
CAS:<p>Piperlongumine (Piplartine) is a natural alkaloid from Piper longum L.</p>Fórmula:C17H19NO5Pureza:97.03% - 99.90%Cor e Forma:SolidPeso molecular:317.34NADPH tetracyclohexanamine
CAS:<p>NADPH tetracyclohexanamine (NADPH (tetracyclohexanamine)) is a cofactor and biological reducing agent.</p>Fórmula:C45H82N11O17P3Pureza:98.73% - 99.05%Cor e Forma:SolidPeso molecular:1142.12L-BUTHIONINE-(S,R)-SULFOXIMINE
CAS:<p>L-Buthionine-(S,R)-sulfoximine is a cell-permeable and irreversible inhibitor of γ-glutamylcysteine synthetase that induces oxidative stress by depleting GSH.</p>Fórmula:C8H18N2O3SPureza:97.07% - ≥98%Cor e Forma:White Fine PowderPeso molecular:222.31ML-210
CAS:<p>ML-210 (CID 49766530) is a glutathione peroxidase 4 (GPX4) inhibitor. ML-210 has antitumor activity and induces ferroptosis. Cost-effective and quality-assured.</p>Fórmula:C22H20Cl2N4O4Pureza:97% - 99.03%Cor e Forma:SolidPeso molecular:475.32Piperazine Erastin
CAS:<p>Piperazine erastin is an analog of erastin. It causes an iron-dependent form of non-apoptotic cell death termed ferroptosis.</p>Fórmula:C35H41ClN6O4Pureza:99.52%Cor e Forma:SolidPeso molecular:645.19RSL3
CAS:<p>View and buy RSL3 from TargetMol.RSL3 is a VDAC-independent ferroptosis activator.Cited in 10 publications.</p>Fórmula:C23H21ClN2O5Pureza:98% - 99.96%Cor e Forma:SolidPeso molecular:440.88TBHQ
CAS:<p>TBHQ (tert-Butylhydroquinone) is an antioxidant that induces an antioxidant response through the redox-sensitive transcription factor Nrf2.</p>Fórmula:C10H14O2Pureza:99.17% - 99.53%Cor e Forma:White Solid PowderPeso molecular:166.22Trolox
CAS:<p>Trolox is a vitamin E analogue, used in reducing oxidative stress or damage.</p>Fórmula:C14H18O4Pureza:98.90% - 99.90%Cor e Forma:White To Fainly Beige Crystalline PowderPeso molecular:250.29Alogliptin
CAS:<p>Alogliptin (SYR-322)(SYR-322) is a potent, selective inhibitor of DPP-4 with IC50 of <10 nM, exhibits greater than 10, 000-fold selectivity over DPP-8 and DPP-9</p>Fórmula:C18H21N5O2Pureza:99.63%Cor e Forma:SolidPeso molecular:339.39Alogliptin Benzoate
CAS:<p>Alogliptin Benzoate, a potent DPP-4 inhibitor with >10,000-fold selectivity over DPP-8/9, may also curb TLR-4-induced inflammation.</p>Fórmula:C25H27N5O4Pureza:99.94% - >99.99%Cor e Forma:White PowderPeso molecular:461.51WITHAFERIN A
CAS:<p>WITHAFERIN A is a novel class of NFkappaB inhibitors, which hold promise as novel anti-inflammatory agents for treatment of various inflammatory disorders and/</p>Fórmula:C28H38O6Pureza:97.41% - 99.99%Cor e Forma:SolidPeso molecular:470.6Bardoxolone Methyl
CAS:<p>Bardoxolone Methyl (TP-155) is a synthetic triterpenoid that acts as an activator of the Nrf2 pathway and an inhibitor of the NF-κB pathway with potential anti-</p>Fórmula:C32H43NO4Pureza:97.81% - 99.09%Cor e Forma:SolidPeso molecular:505.69Siramesine hydrochloride
CAS:<p>Siramesine hydrochloride (Lu 28-179 hydrochloride) is a selective sigma-2 receptor agonist, which has been shown to trigger cell death of Y cells and to exhibit</p>Fórmula:C30H32ClFN2OPureza:99.72% - >99.99%Cor e Forma:SolidPeso molecular:491.04Necrostatin-1
CAS:<p>Necrostatin-1 (Nec-1) is a necrotic apoptosis inhibitor and RIP1 inhibitor with specificity.</p>Fórmula:C13H13N3OSPureza:99.25% - >99.99%Cor e Forma:SolidPeso molecular:259.33JKE-1674
CAS:<p>JKE-1674 is an orally active glutathione peroxidase 4 (GPX4) inhibitor and the active metabolite of ML-210.Cost-effective and quality-assured.</p>Fórmula:C20H20Cl2N4O4Pureza:98.02% - 98.4%Cor e Forma:SolidPeso molecular:451.3Bay 11-7085
CAS:<p>Bay 11-7085 can irreversibly inhibit the IκBα phosphorylation induced by TNFα (IC50: 10 μM).</p>Fórmula:C13H15NO2SPureza:99.76% - 99.94%Cor e Forma:White SolidPeso molecular:249.33DL-Buthionine-(S,R)-sulfoximine
CAS:<p>DL-Buthionine-(S,R)-sulfoximine (Butionine sulfoximine) is an inhibitor of γ-glutamylcysteine synthetase for the treatment of solid tumors.</p>Fórmula:C8H18N2O3SPureza:98% - 99.64%Cor e Forma:White Fine PowderPeso molecular:222.31Coenzyme Q10
CAS:<p>Coenzyme Q10 (CoQ10) (ubiquinone) is a naturally occurring compound, acting as the electron carrier in the mitochondrial respiratory chain.</p>Fórmula:C59H90O4Pureza:99.14% - 99.88%Cor e Forma:DrypowderPeso molecular:863.34ML162
CAS:<p>ML162 is a covalent glutathione peroxidase 4 (GPX4) inhibitor that induces ferroptosis. ML162 has antitumor activity. Cost-effective and quality-assured.</p>Fórmula:C23H22Cl2N2O3SPureza:98.42% - 99.55%Cor e Forma:SolidPeso molecular:477.4(E)-Ferulic acid
CAS:<p>(E)-Ferulic acid ((E)-Coniferic acid) causes the phosphorylation of β-catenin, resulting in proteasomal degradation of β-catenin and increases the expression of</p>Fórmula:C10H10O4Pureza:99.63%Cor e Forma:SolidPeso molecular:194.18D-glutamine
CAS:<p>D-glutamine, an D type stereoisomer of glutamine, is one of the 20 amino acids which is encoded by the standard genetic code.</p>Fórmula:C5H10N2O3Pureza:99.99%Cor e Forma:White Or Off-White PowderPeso molecular:146.14BAY 87-2243
CAS:<p>BAY 87-2243 is a potent and selective inhibitor of hypoxia-inducible factor-1 (HIF-1).</p>Fórmula:C26H26F3N7O2Pureza:98% - 99.95%Cor e Forma:SolidPeso molecular:525.53L-Buthionine-(S,R)-sulfoximine hydrochloride
<p>L-Buthionine-(S,R)-sulfoximine hydrochloride is a fast, irreversible γ-GCS inhibitor that depletes glutathione. IC50: 1.9-29 μM in various tumors.</p>Fórmula:C8H19ClN2O3SCor e Forma:SolidPeso molecular:258.77Liproxstatin-1 hydrochloride
CAS:<p>Liproxstatin-1 hydrochloride is a high-potency ferroptosis inhibitor capable of effectively preventing ferroptotic cell death, with an IC50 value of 22 nM [1].</p>Fórmula:C19H22Cl2N4Cor e Forma:SolidPeso molecular:377.31Pioglitazone potassium
CAS:<p>Pioglitazone potassium is an oral PPARγ agonist with EC50 of 0.93 μM (human) and 0.99 μM (mouse), used in diabetes research.</p>Fórmula:C19H19KN2O3SCor e Forma:SolidPeso molecular:394.53CDDO-Im
CAS:<p>CDDO-Im (TP-235) is an activator of Nrf2 and PPAR (Kis: 232/344 nM for PPARα/PPARγ).</p>Fórmula:C34H43N3O3Pureza:98.3% - 99.61%Cor e Forma:SolidPeso molecular:541.72(-)-Epicatechin
CAS:<p>(-)-Epicatechin (Epicatechin) is an inhibitor of cyclooxygenase-1 (COX-1), inhibiting the IL-1β-induced expression of iNOS by blocking the nuclear localization</p>Fórmula:C15H14O6Pureza:98.55% - 98.80%Cor e Forma:SolidPeso molecular:290.27UAMC-3203 hydrochloride
CAS:<p>UAMC-3203 hydrochloride is a potent and selective Ferroptosis inhibitor with an IC50 of 12 nM.</p>Fórmula:C25H38ClN5O2SPureza:99.62%Cor e Forma:SolidPeso molecular:508.12Baicalein monohydrate
CAS:<p>Baicalein monohydrate blocks 12-lipoxygenase, curbs leukotrienes, lysosomal enzymes, Ca2+ dynamics, and fights arthritis.</p>Fórmula:C15H12O6Cor e Forma:SolidPeso molecular:288.25Ferrostatin-1
CAS:<p>Ferrostatin-1 (Fer-1) is a potent and selective inhibitor of iron death, potently inhibits Erastin-induced iron death in HT-1080 cells. High-Quality, Low-Cost!</p>Fórmula:C15H22N2O2Pureza:96.1% - 99.68%Cor e Forma:SolidPeso molecular:262.35CIL56
CAS:<p>CIL56 (CA3) is a small molecule that induces cellular ferroptosis through the production of iron-dependent reactive oxygen species (ROS).</p>Fórmula:C23H27N3O5S2Pureza:99.46% - 99.91%Cor e Forma:SolidPeso molecular:489.61Hemin
CAS:<p>Hemin (Hemin chloride) is a chlorinated iron-containing porphyrin, a heme oxygenase (HO)-1 inducer.</p>Fórmula:C34H32ClFeN4O4Pureza:97.169% - 99.59%Cor e Forma:Dark Purple Crystalline PowderPeso molecular:651.94DihydroarteMisinic acid
CAS:<p>DihydroarteMisinic acid (Dihydro-Artmisinic Acid) is a natural product from Artemisia annua and the main direct precursor of artemisinin, which is a medicinal</p>Fórmula:C15H24O2Pureza:99.06% - 99.17%Cor e Forma:SolidPeso molecular:236.35Arteannuin B
CAS:<p>1. Arteannuin B has potent antimalarial activity.</p>Fórmula:C15H20O3Pureza:98% - 99.8%Cor e Forma:SolidPeso molecular:248.32Eprenetapopt
CAS:<p>Eprenetapopt (PRIMA-1Met) restores wild-type conformation and function to mutant p53, and triggers apoptosis in tumor cells.</p>Fórmula:C10H17NO3Pureza:98.75% - 99.57%Cor e Forma:SolidPeso molecular:199.25DL-α-Tocopherol
CAS:<p>DL-alpha-Tocopherol (Ephanyl) is a synthetic vitamin E that protects skin fibroblasts from the cytotoxic effects of UV light and has antioxidant properties.</p>Fórmula:C29H50O2Pureza:99.61% - 99.90%Cor e Forma:Light Yellow Liquid ViscousPeso molecular:430.71SRS11-92
CAS:<p>SRS11-92 (AA9) is a ferroptosis inhibitor and a derivative of ferrostatin-1</p>Fórmula:C22H28N2O2Pureza:98.58%Cor e Forma:SolidPeso molecular:352.47Deferitrin
CAS:<p>Deferitrin (GT-56-252) is an iron chelator. It potentially for the treatment of thalassemia and iron overload.</p>Fórmula:C11H11NO4SPureza:98.71%Cor e Forma:SolidPeso molecular:253.271R,3S-RSL 3
CAS:<p>1R,3S-RSL 3 is a harmala alkaloid.</p>Fórmula:C23H21ClN2O5Pureza:99.51%Cor e Forma:SolidPeso molecular:440.88Setanaxib
CAS:<p>Setanaxib (GKT137831) is a potent, specific dual NADPH oxidase (NOX1/4) inhibitor.</p>Fórmula:C21H19ClN4O2Pureza:93.468% - 99.31%Cor e Forma:SolidPeso molecular:394.85Dp44mT
CAS:<p>Dp44mT, a effective iron chelator, has selective antitumor activity.</p>Fórmula:C14H15N5SPureza:99% - 99.02%Cor e Forma:SolidPeso molecular:285.37Nordihydroguaiaretic acid
CAS:<p>Nordihydroguaiaretic acid (NDGA) is a natural lipoxygenase (5-LOX) inhibitor. Nordihydroguaiaretic acid has antioxidant effect. Cost-effective and quality-assured.</p>Fórmula:C18H22O4Pureza:97.82% - 99.91%Cor e Forma:SolidPeso molecular:302.36NADPH tetrasodium salt
CAS:<p>NADPH tetrasodium salt is the reduced form of the electron acceptor nicotinamide adenine dinucleotide phosphate, which acts as an electron donor in a variety of</p>Fórmula:C21H26N7Na4O17P3Pureza:97.15% - >99.99%Cor e Forma:SolidPeso molecular:833.35Troglitazone
CAS:<p>Troglitazone (Romglizone) is a PPARγ agonist with anti-inflammatory and anti-tumor activity.</p>Fórmula:C24H27NO5SPureza:98% - 99.8%Cor e Forma:Yellow SolidPeso molecular:441.54SRS16-86
CAS:<p>SRS16-86 is a novel third-generation ferrostatin, is an inhibitor of ferroptosis.</p>Fórmula:C26H32N4O2Pureza:97.73%Cor e Forma:SolidPeso molecular:432.56Pseudolaric Acid B
CAS:<p>Pseudolaric acid B, a natural diterpenoid compound, is isolated from Pseudolarix kaempferi.</p>Fórmula:C23H28O8Pureza:98.91% - 99.84%Cor e Forma:SolidPeso molecular:432.46Levobupivacaine
CAS:<p>Levobupivacaine is an amino-amide local anaesthetic drug belonging to the family of n-alkylsubstituted pipecoloxylidide.</p>Fórmula:C18H28N2OPureza:99.72%Cor e Forma:SolidPeso molecular:288.43Liproxstatin-1
CAS:<p>Liproxstatin-1 is a potent and selective inhibitor of iron death (IC50=22 nM).</p>Fórmula:C19H21ClN4Pureza:97.11% - 99.44%Cor e Forma:SolidPeso molecular:340.85Rosiglitazone hydrochloride
CAS:<p>Rosiglitazone hydrochloride (BRL-49653 HCl) is a blood glucose-lowering drugs, stimulating insulin secretion by binding to the PPAR receptors in fat cells.</p>Fórmula:C18H19N3O3S·HClPureza:99.63% - 99.79%Cor e Forma:SolidPeso molecular:393.89SP600125
CAS:<p>SP600125 (JNK Inhibitor II) is a JNK inhibitor that inhibits JNK1, JNK2, and JNK3 (IC50=40/40/90 nM) with oral potency, reversibility, and ATP-competitive</p>Fórmula:C14H8N2OPureza:97.63% - 99.82%Cor e Forma:SolidPeso molecular:220.23L-Cystine
CAS:<p>L-Cystine (Cystine Acid) is not considered one of the 20 amino acids, L-Cystine (Cystine Acid) is a sulfur-containing derivative obtained from oxidation of</p>Fórmula:C6H12N2O4S2Pureza:99.59% - 99.85%Cor e Forma:White Solid PowderPeso molecular:240.30Rosiglitazone
CAS:<p>Rosiglitazone (BRL49653) is a PPARγ agonist, TRPC5 activator, and TRPM3 inhibitor with oral activity.</p>Fórmula:C18H19N3O3SPureza:98.61% - 99.87%Cor e Forma:White To Off-White Crystalline PowderPeso molecular:357.43L-Glutamic acid
CAS:<p>L-Glutamic acid is an agonist of glutamate receptors, including metabotropic glutamate receptors (mGluR), AMPA, NMDA, and KA. High-Quality, Low-Cost!</p>Fórmula:C5H9NO4Pureza:99.14% - 99.55%Cor e Forma:White Solid CrystallinePeso molecular:147.13ML385
CAS:<p>ML385 is an NRF2 inhibitor (IC50=1.9 μM) with novelty and specificity.</p>Fórmula:C29H25N3O4SPureza:98.08% - >99.99%Cor e Forma:SolidPeso molecular:511.59Trigonelline
CAS:<p>Trigonelline (Trigenolline), an alkaloid with potential antidiabetic activity, is present in considerable amounts in coffee.</p>Fórmula:C7H7NO2Pureza:97.585% - 99.49%Cor e Forma:Prisms Aqueous From Alcohol + Water SolidPeso molecular:137.14PRIMA-1
CAS:<p>PRIMA-1 (NSC-281668) is a mutant p53 reactivator. It induces apoptosis and inhibits growth of human tumors with mutant p53.</p>Fórmula:C9H15NO3Pureza:99.22%Cor e Forma:SolidPeso molecular:185.22Atorvastatin hemicalcium salt
CAS:<p>Atorvastatin hemicalcium salt (Atorvastatin Calcium) is an orally HMG-CoA reductase inhibitor that lowers cholesterol. Cost-effective and quality-assured.</p>Fórmula:C33H34FN2O5CaPureza:99.27% - >99.99%Cor e Forma:White Crystalline PowderPeso molecular:577.67Erastin
CAS:<p>Erastin is an iron death activator that acts on the mitochondrial VDAC in a ROS- and iron-dependent manner, anti-tumor. High-Quality, Low-Cost!</p>Fórmula:C30H31ClN4O4Pureza:98% - 99.75%Cor e Forma:SolidPeso molecular:547.04FIN56
CAS:<p>FIN56 is a specific inducer of ferroptosis.</p>Fórmula:C25H31N3O5S2Pureza:99.72% - 99.78%Cor e Forma:SolidPeso molecular:517.66PD146176
CAS:<p>PD146176 (NSC-168807) is an inhibitor of 15-Lipoxygenase (15-LO) , it inhibits rabbit reticulocyte 15-LO with Ki of 197 nM and IC50 of 0.54 μM.</p>Fórmula:C15H11NSPureza:98.00%Cor e Forma:SolidPeso molecular:237.32Pifithrin-α hydrobromide
CAS:<p>Pifithrin-α hydrobromide (Pifithrin-α hydrobromide) is a p53 inhibitor, inhibiting p53-dependent transactivation of p53-responsive genes.</p>Fórmula:C16H18N2OS·HBrPureza:97.71% - >99.99%Cor e Forma:SolidPeso molecular:367.3Pifithrin-β hydrobromide
CAS:<p>Pifithrin-β hydrobromide (Cyclic PFT-α) is an inhibitor of p53; reversibly blocks p53-dependent transcriptional activation and apoptosis.</p>Fórmula:C16H17BrN2SPureza:99.24% - 99.74%Cor e Forma:SolidPeso molecular:349.29Levobupivacaine hydrochloride
CAS:<p>Levobupivacaine hydrochloride ((S)-(-)-Bupivacaine monohydrochloride) is a reversible neuronal sodium channel inhibitor, used as a long-acting local anesthetic.</p>Fórmula:C18H28N2O·HClPureza:99.74%Cor e Forma:White Crystalline PowderPeso molecular:324.89Ammonium iron(III) citrate
CAS:<p>Ammonium iron(III) citrate (Ferric ammonium citrate) is a physiological form of non-ferritin-bound iron that causes intracellular iron overload and iron death.</p>Fórmula:C24H32Fe3N3O28Pureza:98%Cor e Forma:Ferric Ammonium Citrate Is A Yellowish Brown To Red Solid With A Faint Odor Of AmmoniaPeso molecular:978.05U-73122
CAS:<p>U-73122 (U73122) , an effective PLC inhibitor, reduces agonist-induced Ca2+ increases in platelets and PMN.</p>Fórmula:C29H40N2O3Pureza:97.50%Cor e Forma:Solid Off-WhitePeso molecular:464.64UAMC-3203
CAS:<p>UAMC-3203 is a potent and selective Ferroptosis inhibitor (IC50: 12 nM).</p>Fórmula:C25H37N5O2SPureza:97.052% - 99.72%Cor e Forma:SolidPeso molecular:471.66FINO2
CAS:<p>FINO2, a strong ferroptosis trigger, blocks GPX4, oxidizes Fe2+, stable in different pH, causes lipid peroxidation.</p>Fórmula:C15H28O3Pureza:97.27%Cor e Forma:SoildPeso molecular:256.38Microtubule inhibitor 8
CAS:<p>Microtubule Inhibitor 8 (MP-HJ-1b) serves as a potent disruptor of microtubule function, inducing cell death via ferroptosis and demonstrating anti-tumor effects [1] [2].</p>Fórmula:C21H15N3O2SCor e Forma:SolidPeso molecular:373.43Pioglitazone-d4
CAS:<p>Pioglitazone D4 is a deuterium labeled Pioglitazone. Pioglitazone is a agonist of PPARγ .</p>Fórmula:C19H20N2O3SPureza:98%Cor e Forma:SolidPeso molecular:360.46W1131
CAS:<p>W1131 is a potent STAT3 inhibitor and ferroptosis trigger, reducing cancer progression and 5-FU resistance.</p>Fórmula:C23H19N5O4Cor e Forma:SolidPeso molecular:429.43YL-939
<p>YL-939 is a potent inhibitor of ferroptosis, targeting the PHB2/ferritin/iron axis to impede this form of cell death.</p>Fórmula:C25H26N6OCor e Forma:SolidPeso molecular:426.51Ferroptosis inducer-1
CAS:<p>Ferroptosis inducer-1 is a Ferroptosis inducer with antitumor potential .</p>Fórmula:C25H21ClN2O5Cor e Forma:SolidPeso molecular:464.9CN128 hydrochloride
CAS:<p>CN128 hydrochloride is an oral, selective hydroxypyridone iron chelator for β-thalassemia research.</p>Fórmula:C15H18ClNO3Cor e Forma:SolidPeso molecular:295.76Anticancer agent 147
CAS:<p>Compound 6j (Anticancer agent 147), a sophoridine derivative and ferroptosis inducer, promotes intracellular accumulation of Fe2+, reactive oxygen species (ROS</p>Fórmula:C32H40BrN3O2Pureza:98%Cor e Forma:SolidPeso molecular:578.58Tubulin inhibitor 30
CAS:<p>Tubulin Inhibitor 30, exhibiting an IC50 value of 0.52 μM, functions as an inhibitor of tubulin assembly. Additionally, it can induce ferroptosis.</p>Fórmula:C22H19N3O5Cor e Forma:SolidPeso molecular:405.4IM-93
CAS:<p>IM-93 inhibits ferroptosis and NETosis with an IC< sub>50 of 0.45 μM for cell death inhibition [1].</p>Fórmula:C21H28N4O2Cor e Forma:SolidPeso molecular:368.47CGP 65015
CAS:<p>CGP 65015 is an oral iron chelator and can mobilize iron deposits.</p>Fórmula:C14H15NO4Pureza:98%Cor e Forma:SolidPeso molecular:261.27FA16
<p>FA16 is a selective, metabolically stable ferroptosis inducer with an IC50 value of 1.26 μM.FA16 is a derivative of 2-(trifluoromethyl)benzimidazole.FA16</p>Fórmula:C22H27F3N4O2SPureza:99.44%Cor e Forma:SolidPeso molecular:468.54Deferitazole
CAS:<p>Deferitazole (FBS 0701) is a novel and orally active, selective and high affinity iron chelator.</p>Fórmula:C18H25NO7SPureza:99.48%Cor e Forma:SolidPeso molecular:399.46Erastin2
CAS:<p>Erastin2 is an iron death inducer that induces cell death by binding to the lipophilic free radical trapping antioxidant ferrostatin-1 or the iron chelator DFO.</p>Fórmula:C36H35ClN4O4Pureza:99.63%Cor e Forma:SolidPeso molecular:623.14HBED
CAS:<p>HBED (CHELII) is an iron chelator and can be used in research on the treatment of chronic iron overload and acute iron poisoning.</p>Fórmula:C20H24N2O6Pureza:97.35% - 98.58%Cor e Forma:SolidPeso molecular:388.41BCP-T.A
CAS:<p>BCP-T.A is an iron death inducer that acts by binding to GPX4.</p>Fórmula:C23H19Cl2N3OSPureza:99.49%Cor e Forma:SolidPeso molecular:456.39Lepadin E
CAS:<p>Lepadin E, a notably cytotoxic compound, effectively stimulates ferroptosis via the canonical p53-SLC7A11-GPX4 pathway.</p>Fórmula:C26H47NO3Pureza:98%Cor e Forma:SolidPeso molecular:421.66CP-24879 hydrochloride
CAS:<p>CP-24879 HCl, a Δ5D/Δ6D dual-inhibitor, reduces liver lipid buildup and inflammation.</p>Fórmula:C11H18ClNOPureza:98.08%Cor e Forma:SolidPeso molecular:215.72Docebenone
CAS:<p>Docebenone is a selective and orally active inhibitor of 5-LO.</p>Fórmula:C21H26O3Cor e Forma:SolidPeso molecular:326.43Ferroptocide
CAS:<p>Ferroptocide is a thioredoxin inhibitor that induces iron death in cancer cells and can be used in breast cancer research.</p>Fórmula:C30H36ClN3O7Cor e Forma:SolidPeso molecular:586.08Ogremorphin
CAS:<p>Ogremorphin (GPR68-IN-1) is a potent inhibitor of GPR68, exhibiting an EC50 of 170 nM.it is utilized in the study of autoimmune chronic inflammatory diseases [1</p>Fórmula:C21H17N3OSPureza:99.65% - 99.65%Cor e Forma:SolidPeso molecular:359.44Lepadin H
CAS:<p>Lepadin H, a marine alkaloid and ferroptosis inducer, exhibits significant cytotoxicity by promoting p53 expression, escalating ROS production, and enhancing</p>Fórmula:C26H45NO3Pureza:98%Cor e Forma:SolidPeso molecular:419.64viFSP1
CAS:<p>viFSP1, a species-independent FSP1 inhibitor, effectively induces ferroptosis in FSP1-dependent cells by targeting the highly conserved NAD(P)H binding pocket of FSP1, directly inhibiting its activity. This action results in lipid peroxidation and exhibits anticancer activity [1].</p>Fórmula:C16H17N3O3SCor e Forma:SolidPeso molecular:331.39
