Ferroptose
A ferroptose é uma forma de morte celular regulada caracterizada pelo acúmulo de peróxidos lipídicos e estresse oxidativo dependente de ferro. Ao contrário da apoptose, a ferroptose não é impulsionada por caspases, mas pelo fracasso das defesas antioxidantes celulares, levando à morte celular. Inibidores e indutores de ferroptose são críticos para estudar essa via única de morte celular, que está implicada em várias doenças, incluindo câncer, neurodegeneração e lesão por isquemia-reperfusão. Na CymitQuimica, oferecemos uma ampla gama de moduladores de ferroptose de alta qualidade para apoiar sua pesquisa em mecanismos de morte celular, estresse oxidativo e patologia de doenças.
Foram encontrados 215 produtos de "Ferroptose"
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Pravastatin sodium
CAS:<p>Pravastatin sodium (CS-514 (sodium)), an HMG-CoA reductase inhibitor, inhibits sterol synthesis with IC50 of 5.6 μM.</p>Fórmula:C23H35NaO7Pureza:97.14%Cor e Forma:White Crystalline PowderPeso molecular:446.52FSEN1
CAS:<p>FSEN1 is a novel and highly effective non-competitive FSP1 inhibitor with an IC50 value of 313 nM.</p>Fórmula:C22H22BrN5OSPureza:98.56% - 99.54%Cor e Forma:SolidPeso molecular:484.41Ciclopirox olamine
CAS:<p>Ciclopirox olamine is a broad-spectrum antifungal agent with additional antibacterial and anti-inflammatory activities.</p>Fórmula:C14H24N2O3Pureza:99.16% - >99.99%Cor e Forma:White To Yellow Solid Solid Particulate/PowderPeso molecular:268.35Ethylenediaminetetraacetic acid trisodium salt
CAS:<p>Ethylenediaminetetraacetic acid trisodium salt (EDTA Trisodium) used to bind metal ions in the chelation therapy.</p>Fórmula:C10H13N2Na3O8Pureza:99.92% - 99.96%Cor e Forma:White CrystalsPeso molecular:358.19Sorafenib
CAS:<p>Sorafenib (Bay 43-9006) is a multikinase inhibitor that inhibits Raf-1, B-Raf, VEGFR2, VEGFR3, VEGFR4, PDGFRβ, FLT3, c-Kit, and others (IC50=6/22/90/15/20/20/57</p>Fórmula:C21H16ClF3N4O3Pureza:98% - 99.89%Cor e Forma:SolidPeso molecular:464.82Imidazole ketone erastin
CAS:<p>View and buy Imidazole ketone erastin from TargetMol.Imidazole ketone erastin (IKE) is an inducer of ferroptosis. It has inhibition of the system Xc- cystine/glutamate transporter.Cited in 22 publications.</p>Fórmula:C35H35ClN6O5Pureza:98.48% - 99.87%Cor e Forma:SolidPeso molecular:655.14Butylated hydroxytoluene
CAS:<p>Butylated hydroxytoluene (BHT FCC/NF) is an organic chemical composed of 4-methylphenol modified with tert-butyl groups at positions 2 and 6.</p>Fórmula:C15H24OPureza:99.72%Cor e Forma:Colourless Solid PowderPeso molecular:220.35iFSP1
CAS:<p>iFSP1, a potent, selective, and glutathione-independent ferroptosis suppressor protein 1 (FSP1) (AIFM2) inhibitor with an EC50 of 103 nM, sensitizes diverse</p>Fórmula:C20H13N5Pureza:98.74% - 99.74%Cor e Forma:SolidPeso molecular:323.35Zileuton
CAS:<p>Zileuton (A 64077) inhibits 5-lipoxygenase, reduces leukotrienes, aids bronchodilation, lessens mucus/edema, and helps manage asthma symptoms.</p>Fórmula:C11H12N2O2SPureza:98.72% - 99.43%Cor e Forma:Crystalline SolidPeso molecular:236.29Sorafenib tosylate
CAS:<p>Sorafenib tosylate (Bay 43-9006) is a potent multikinase inhibitor (IC50s: 6/20/22 nM for Raf-1/VEGFR-3/B-Raf).</p>Fórmula:C21H16ClF3N4O3·C7H8O3SPureza:99.24% - 99.94%Cor e Forma:White To Off-White Crystalline PowderPeso molecular:637.03Lovastatin
CAS:<p>Lovastatin (MK-803) is an HMG-CoA reductase inhibitor. Lovastatin lowers cholesterol and is used as a lipid-lowering agent. Cost-effective and quality-assured.</p>Fórmula:C24H36O5Pureza:99.66% - 99.92%Cor e Forma:The Substance Is A White-Yellowish To Yellow Powder Solid PowderPeso molecular:404.54Linagliptin
CAS:<p>Linagliptin (BI 1356) is a potent, orally bioavailable dihydropurinedione-based inhibitor of dipeptidyl peptidase 4 (DPP-4), with hypoglycemic activity.</p>Fórmula:C25H28N8O2Pureza:99.15% - >99.99%Cor e Forma:SolidPeso molecular:472.54Simvastatin
CAS:<p>Simvastatin (MK 733) is an HMG-CoA reductase inhibitor (Ki=0.2 nM) with oral activity.</p>Fórmula:C25H38O5Pureza:98.54% - 99.13%Cor e Forma:SolidPeso molecular:418.57Sulfasalazine
CAS:<p>Sulfasalazine (Azulfidine) is a synthetic salicylic acid derivative. Sulfasalazine induces ferroptosis and inhibits NF-κB. Cost effective and quality assured.</p>Fórmula:C18H14N4O5SPureza:98.00% - 99.28%Cor e Forma:Minute Brownish-Yellow CrystalsPeso molecular:398.39Eugenol
CAS:<p>Eugenol (Allylguaiacol) is a Standardized Chemical Allergen.</p>Fórmula:C10H12O2Pureza:98.03%Cor e Forma:Colorless Or Pale Yellow Liquid Pungent Taste (Ntp 1992)Peso molecular:164.22-(10-hydroxydecyl)-6-methoxy-3-methyl-5-(trideuteriomethoxy)cyclohexa-2,5-diene-1,4-dione
CAS:Fórmula:C19H30O5Pureza:98%Cor e Forma:SolidPeso molecular:338.4385Dopamine hydrochloride
CAS:<p>Dopamine hydrochloride (ASL279) is a natural catecholamine neurotransmitter, dopamine receptors (D1-5 receptors) (EC50=2.7 nM). High-Quality, Low-Cost!</p>Fórmula:C8H12ClNO2Pureza:99.47% - 99.72%Cor e Forma:SolidPeso molecular:189.64Fluvastatin sodium
CAS:<p>Fluvastatin sodium (Fluvastatin sodium salt), a competitive inhibitor of hydroxymethylglutaryl-coenzyme A reductase (HMGCR), is a commonly used cholesterol</p>Fórmula:C24H25FNNaO4Pureza:98.54% - 99.56%Cor e Forma:Light Yellow Solid PowderPeso molecular:433.45Deferasirox
CAS:<p>Deferasirox (CGP-72670) is an oral iron chelating agent used to treat chronic iron overload.</p>Fórmula:C21H15N3O4Pureza:98.79% - 99.4%Cor e Forma:SolidPeso molecular:373.36Cisplatin
CAS:<p>Cisplatin (CDDP) is a DNA cross-linking agent.</p>Fórmula:Cl2H6N2PtPureza:97.13% - 99.63%Cor e Forma:Orange-Yellow To Deep Yellow Solid Or PowderPeso molecular:300.04
