Ferroptose
A ferroptose é uma forma de morte celular regulada caracterizada pelo acúmulo de peróxidos lipídicos e estresse oxidativo dependente de ferro. Ao contrário da apoptose, a ferroptose não é impulsionada por caspases, mas pelo fracasso das defesas antioxidantes celulares, levando à morte celular. Inibidores e indutores de ferroptose são críticos para estudar essa via única de morte celular, que está implicada em várias doenças, incluindo câncer, neurodegeneração e lesão por isquemia-reperfusão. Na CymitQuimica, oferecemos uma ampla gama de moduladores de ferroptose de alta qualidade para apoiar sua pesquisa em mecanismos de morte celular, estresse oxidativo e patologia de doenças.
Foram encontrados 215 produtos de "Ferroptose"
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Simvastatin
CAS:Fórmula:C25H38O5Pureza:>97.0%(HPLC)Cor e Forma:White to Almost white powder to crystalPeso molecular:418.57Coenzyme Q10
CAS:Fórmula:C59H90O4Pureza:>98.0%(HPLC)Cor e Forma:Light yellow to Yellow to Orange powder to crystalPeso molecular:863.37Sulfasalazine
CAS:Fórmula:C18H14N4O5SPureza:>95.0%(T)(HPLC)Cor e Forma:Light yellow to Amber to Dark green powder to crystalPeso molecular:398.39Ferrostatin-1
CAS:Fórmula:C15H22N2O2Pureza:>98.0%(HPLC)Cor e Forma:White to Amber to Dark purple powder to crystalPeso molecular:262.35Coenzyme Q9
CAS:Fórmula:C54H82O4Pureza:>98.0%(HPLC)Cor e Forma:Light yellow to Yellow to Orange powder to crystalPeso molecular:795.25L-Glutamic Acid
CAS:Fórmula:C5H9NO4Pureza:>99.0%(T)Cor e Forma:White powder to crystalPeso molecular:147.13Baicalein
CAS:Fórmula:C15H10O5Pureza:>98.0%(T)Cor e Forma:Light yellow to Amber to Dark green powder to crystalPeso molecular:270.246-Hydroxy-2,5,7,8-tetramethylchroman-2-carboxylic Acid
CAS:Fórmula:C14H18O4Pureza:>98.0%(GC)(T)Cor e Forma:White to Orange to Green powder to crystalinePeso molecular:250.29Ebselen
CAS:Fórmula:C13H9NOSePureza:>98.0%(GC)Cor e Forma:Light orange to Yellow to Green powder to crystalPeso molecular:274.18Erastin
CAS:Fórmula:C30H31ClN4O4Pureza:>98.0%(HPLC)(qNMR)Cor e Forma:White to Light yellow powder to crystalPeso molecular:547.05Acetylcysteine
CAS:<p>Acetylcysteine (NAC) is an N-acetyl derivative of cysteine, a ROS inhibitor and mucolytic agent.</p>Fórmula:C5H9NO3SPureza:98.01% - >99.99%Cor e Forma:Crystals From Water SolidPeso molecular:163.19Pioglitazone
CAS:<p>Pioglitazone (U 72107) is a selective and oral PPARγ agonist with EC50 of 0.93 and 0.99 μM on human and mouse PPARγ, respectively . High-Quality, Low-Cost!</p>Fórmula:C19H20N2O3SPureza:95% - 99.57%Cor e Forma:White PowderPeso molecular:356.44Lapatinib
CAS:<p>Lapatinib (GW572016) is an inhibitor of ErbB2 and EGFR (IC50=9.2/10.8 nM) with oral activity.</p>Fórmula:C29H26ClFN4O4SPureza:99.00% - 99.81%Cor e Forma:PowderPeso molecular:581.06α-Vitamin E
CAS:<p>α-Vitamin E (Dexrabeprazole Sodium) is a naturally-occurring form of vitamin E, a fat-soluble vitamin with potent antioxidant properties.</p>Fórmula:C29H50O2Pureza:98% - 99.89%Cor e Forma:Light Yellow LiquidPeso molecular:430.71Deferasirox
CAS:<p>Deferasirox (CGP-72670) is an oral iron chelating agent used to treat chronic iron overload.</p>Fórmula:C21H15N3O4Pureza:98.79% - 99.4%Cor e Forma:SolidPeso molecular:373.36Artemisinin
CAS:<p>Artemisinin (Qinghaosu) is a natural sesquiterpene lactone. Artemisinin has anti-malarial, neuroprotective and anti-tumor effects. Cost-effective and quality-assured.</p>Fórmula:C15H22O5Pureza:99.77% - 99.87%Cor e Forma:Crystalline SolidPeso molecular:282.33Artesunate
CAS:<p>Artesunate (WR-256283) is part of the artemisinin group of drugs that treat malaria.</p>Fórmula:C19H28O8Pureza:97.67% - 99.9%Cor e Forma:White Crystalline PowderPeso molecular:384.42Gallic acid
CAS:<p>Gallic acid (Benzoic acid) is found in almost all plants. Plants known for their high gallic acid content include gallnuts,grapes,tea,hops and oak bark.</p>Fórmula:C7H6O5Pureza:99.38% - 99.57%Cor e Forma:White Solid Solid Particulate/PowderPeso molecular:170.12Lapatinib ditosylate monohydrate
CAS:<p>Lapatinib ditosylate monohydrate: a drug for advanced breast cancer; may cause liver issues.</p>Fórmula:C29H26ClFN4O4S·2(C7H8O3S)·H2OPureza:98% - 99.41%Cor e Forma:Colourless To Light-Yellow CrystalPeso molecular:943.47Lapatinib Ditosylate
CAS:<p>Lapatinib Ditosylate (Tykerb ditosylate) is an effective EGFR and ErbB2 inhibitor (IC50: 10.8/9.2 nM for EGFR/ErbB2).</p>Fórmula:C29H26ClFN4O4S·2C7H8O3SPureza:99.41%Cor e Forma:Yellow SolidPeso molecular:925.46DL-Glutamine
CAS:<p>DL-Glutamine, a non-essential amino acid, is abundant in the body, aids metabolism, carries nitrogen, and fuels cells.</p>Fórmula:C5H10N2O3Pureza:99.89%Cor e Forma:White Crystalline Powder White Crystalline PowderPeso molecular:146.14Sorafenib tosylate
CAS:<p>Sorafenib tosylate (Bay 43-9006) is a potent multikinase inhibitor (IC50s: 6/20/22 nM for Raf-1/VEGFR-3/B-Raf).</p>Fórmula:C21H16ClF3N4O3·C7H8O3SPureza:99.24% - 99.94%Cor e Forma:White To Off-White Crystalline PowderPeso molecular:637.03Cisplatin
CAS:<p>Cisplatin (CDDP) is a DNA cross-linking agent.</p>Fórmula:Cl2H6N2PtPureza:97.13% - 99.63%Cor e Forma:Orange-Yellow To Deep Yellow Solid Or PowderPeso molecular:300.04Ethylenediaminetetraacetic acid trisodium salt
CAS:<p>Ethylenediaminetetraacetic acid trisodium salt (EDTA Trisodium) used to bind metal ions in the chelation therapy.</p>Fórmula:C10H13N2Na3O8Pureza:99.92% - 99.96%Cor e Forma:White CrystalsPeso molecular:358.19Sorafenib
CAS:<p>Sorafenib (Bay 43-9006) is a multikinase inhibitor that inhibits Raf-1, B-Raf, VEGFR2, VEGFR3, VEGFR4, PDGFRβ, FLT3, c-Kit, and others (IC50=6/22/90/15/20/20/57</p>Fórmula:C21H16ClF3N4O3Pureza:98% - 99.89%Cor e Forma:SolidPeso molecular:464.82Imidazole ketone erastin
CAS:<p>View and buy Imidazole ketone erastin from TargetMol.Imidazole ketone erastin (IKE) is an inducer of ferroptosis. It has inhibition of the system Xc- cystine/glutamate transporter.Cited in 22 publications.</p>Fórmula:C35H35ClN6O5Pureza:98.48% - 99.87%Cor e Forma:SolidPeso molecular:655.14Butylated hydroxytoluene
CAS:<p>Butylated hydroxytoluene (BHT FCC/NF) is an organic chemical composed of 4-methylphenol modified with tert-butyl groups at positions 2 and 6.</p>Fórmula:C15H24OPureza:99.72%Cor e Forma:Colourless Solid PowderPeso molecular:220.35iFSP1
CAS:<p>iFSP1, a potent, selective, and glutathione-independent ferroptosis suppressor protein 1 (FSP1) (AIFM2) inhibitor with an EC50 of 103 nM, sensitizes diverse</p>Fórmula:C20H13N5Pureza:98.74% - 99.74%Cor e Forma:SolidPeso molecular:323.35Dopamine hydrochloride
CAS:<p>Dopamine hydrochloride (ASL279) is a natural catecholamine neurotransmitter, dopamine receptors (D1-5 receptors) (EC50=2.7 nM). High-Quality, Low-Cost!</p>Fórmula:C8H12ClNO2Pureza:99.47% - 99.72%Cor e Forma:SolidPeso molecular:189.64Deferiprone
CAS:<p>Deferiprone (Deferidone) is an Iron Chelator. The mechanism of action of deferiprone is as an Iron Chelating Activity.</p>Fórmula:C7H9NO2Pureza:99.58% - ≥95%Cor e Forma:White NeedlesPeso molecular:139.15Matrine
CAS:<p>Matrine (Vegard), an alkaloid isolated from the Sophora genus, acts as a kappa opioid receptor agonist.</p>Fórmula:C15H24N2OPureza:97.16% - >99.99%Cor e Forma:SolidPeso molecular:248.36Zileuton
CAS:<p>Zileuton (A 64077) inhibits 5-lipoxygenase, reduces leukotrienes, aids bronchodilation, lessens mucus/edema, and helps manage asthma symptoms.</p>Fórmula:C11H12N2O2SPureza:98.72% - 99.43%Cor e Forma:Crystalline SolidPeso molecular:236.292-(10-hydroxydecyl)-6-methoxy-3-methyl-5-(trideuteriomethoxy)cyclohexa-2,5-diene-1,4-dione
CAS:Fórmula:C19H30O5Pureza:98%Cor e Forma:SolidPeso molecular:338.4385Eugenol
CAS:<p>Eugenol (Allylguaiacol) is a Standardized Chemical Allergen.</p>Fórmula:C10H12O2Pureza:98.03%Cor e Forma:Colorless Or Pale Yellow Liquid Pungent Taste (Ntp 1992)Peso molecular:164.2L-Glutathione reduced
CAS:<p>L-Glutathione reduced (Glutathione) is a naturally occurring tripeptide found in cells as an endogenous antioxidant that scavenges oxygen free radicals.</p>Fórmula:C10H17N3O6SPureza:97.37% - 99.99%Cor e Forma:SolidPeso molecular:307.32Lovastatin
CAS:<p>Lovastatin (MK-803) is an HMG-CoA reductase inhibitor. Lovastatin lowers cholesterol and is used as a lipid-lowering agent. Cost-effective and quality-assured.</p>Fórmula:C24H36O5Pureza:99.66% - 99.92%Cor e Forma:The Substance Is A White-Yellowish To Yellow Powder Solid PowderPeso molecular:404.54Linagliptin
CAS:<p>Linagliptin (BI 1356) is a potent, orally bioavailable dihydropurinedione-based inhibitor of dipeptidyl peptidase 4 (DPP-4), with hypoglycemic activity.</p>Fórmula:C25H28N8O2Pureza:99.15% - >99.99%Cor e Forma:SolidPeso molecular:472.54Simvastatin
CAS:<p>Simvastatin (MK 733) is an HMG-CoA reductase inhibitor (Ki=0.2 nM) with oral activity.</p>Fórmula:C25H38O5Pureza:98.54% - 99.13%Cor e Forma:SolidPeso molecular:418.57FSEN1
CAS:<p>FSEN1 is a novel and highly effective non-competitive FSP1 inhibitor with an IC50 value of 313 nM.</p>Fórmula:C22H22BrN5OSPureza:98.56% - 99.54%Cor e Forma:SolidPeso molecular:484.41Curcumin
CAS:<p>Curcumin (Natural Yellow 3) is a phenolic natural product, an inhibitor of histone acetyltransferase p300/CREB (IC50=25 μM) with specificity.</p>Fórmula:C21H20O6Pureza:95% - 98.98%Cor e Forma:Orange-Yellow Crystal Powder; Gives Brownish-Red Color With Alkali; Light-Yellow Color With Acids Physical Description Orange-Yellow Needles (Ntp 1992)Peso molecular:368.3799Ciclopirox
CAS:<p>Ciclopirox is an antifungal that chelates Fe3+ and Al3+, inhibiting enzymes and has antibacterial and anti-inflammatory effects.</p>Fórmula:C12H17NO2Pureza:97.72% - 99.78%Cor e Forma:SolidPeso molecular:207.27NVS-ZP7-4
CAS:<p>NVS-ZP7-4 is a inhibitor of Zinc transporter SLC39A7 (ZIP7).</p>Fórmula:C28H28FN5OSPureza:99.86%Cor e Forma:SolidPeso molecular:501.62Butylhydroxyanisole
CAS:<p>BHA is an antioxidant with two isomers: 2-tert-butyl-4-hydroxyanisole and 3-tert-butyl-4-hydroxyanisole.</p>Fórmula:C11H16O2Pureza:99.54% - 99.63%Cor e Forma:White Solid WaxyPeso molecular:180.25Vildagliptin
CAS:<p>Vildagliptin (LAF237), an oral DPP-4 inhibitor with hypoglycemic effects, is metabolized and excreted in urine.</p>Fórmula:C17H25N3O2Pureza:97.81% - >99.99%Cor e Forma:White Crystalline PowderPeso molecular:303.40Sulfasalazine
CAS:<p>Sulfasalazine (Azulfidine) is a synthetic salicylic acid derivative. Sulfasalazine induces ferroptosis and inhibits NF-κB. Cost effective and quality assured.</p>Fórmula:C18H14N4O5SPureza:98.00% - 99.28%Cor e Forma:Minute Brownish-Yellow CrystalsPeso molecular:398.39Fluvastatin sodium
CAS:<p>Fluvastatin sodium (Fluvastatin sodium salt), a competitive inhibitor of hydroxymethylglutaryl-coenzyme A reductase (HMGCR), is a commonly used cholesterol</p>Fórmula:C24H25FNNaO4Pureza:98.54% - 99.56%Cor e Forma:Light Yellow Solid PowderPeso molecular:433.45Ciclopirox olamine
CAS:<p>Ciclopirox olamine is a broad-spectrum antifungal agent with additional antibacterial and anti-inflammatory activities.</p>Fórmula:C14H24N2O3Pureza:99.16% - >99.99%Cor e Forma:White To Yellow Solid Solid Particulate/PowderPeso molecular:268.35Pravastatin sodium
CAS:<p>Pravastatin sodium (CS-514 (sodium)), an HMG-CoA reductase inhibitor, inhibits sterol synthesis with IC50 of 5.6 μM.</p>Fórmula:C23H35NaO7Pureza:97.14%Cor e Forma:White Crystalline PowderPeso molecular:446.52Pioglitazone hydrochloride
CAS:<p>Pioglitazone hydrochloride (AD 4833) is the hydrochloride salt of an orally-active thiazolidinedione with antidiabetic properties and potential antineoplastic</p>Fórmula:C19H20N2O3S·HClPureza:99.64% - >99.99%Cor e Forma:White Crystals Or Crystalline PowderPeso molecular:392.90Rosiglitazone maleate
CAS:<p>Rosiglitazone maleate (BRL 49653) is an oral antidiabetic and potential anticancer agent.</p>Fórmula:C22H23N3O7SPureza:99.33% - 99.51%Cor e Forma:Off-White SolidPeso molecular:473.50
