Cromatina/Epigenética
Os inibidores de cromatina/epigenética são compostos que modulam a estrutura e função da cromatina ou interferem em modificações epigenéticas, como a metilação do DNA e a modificação de histonas. Esses inibidores são ferramentas essenciais para estudar a regulação da expressão gênica e o papel da epigenética em doenças como o câncer, distúrbios neurológicos e anomalias do desenvolvimento. Ao direcionar os processos epigenéticos, esses inibidores podem alterar os padrões de expressão gênica e oferecer novas vias terapêuticas. Na CymitQuimica, oferecemos uma ampla seleção de inibidores de cromatina/epigenética de alta qualidade para apoiar sua pesquisa em biologia molecular, genética e epigenética.
Subcategorias de "Cromatina/Epigenética"
Foram encontrados 2410 produtos de "Cromatina/Epigenética"
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JAK2 Inhibitor V
CAS:<p>JAK2 Inhibitor V (JAK2 Inhibitor V Z3) is a novel specific inhibitor of Jak2, inhibiting Jak2-V617F and Jak2-WT autophosphorylation in a dose-dependent manner.</p>Fórmula:C23H24N2OPureza:98.36% - 99.15%Cor e Forma:SolidPeso molecular:344.45SNDX-5613
CAS:Revumenib (SNDX-5613) is a potent and selective oral inhibitor of menin-KMT2A interaction.Cost-effective and quality-assured.Fórmula:C32H47FN6O4SPureza:99.12% - 99.74%Cor e Forma:SolidPeso molecular:630.82A-395
CAS:<p>A-395 blocks PRC2 (EZH2-EED-SUZ12) interactions, strongly inhibiting the complex with an IC50 of 18 nM.</p>Fórmula:C26H35FN4O2SPureza:98.43%Cor e Forma:SolidPeso molecular:486.65Fenbendazole
CAS:Fenbendazole (Fenbendazol) is an antinematodal benzimidazole used in veterinary medicine.Fórmula:C15H13N3O2SPureza:99.74%Cor e Forma:White To Yellowish PowderPeso molecular:299.35GNE-781
CAS:GNE-781: potent CBP inhibitor (IC50: 0.94 nM), also targets BRET/BRD4(1) (IC50: 6.2/5100 nM).Fórmula:C27H33F2N7O2Pureza:99.25% - 99.64%Cor e Forma:SolidPeso molecular:525.59Glucosamine hydrochloride
CAS:Glucosamine hydrochloride (Chitosamine hydrochloride) is commonly used as a treatment for osteoarthritis, although its acceptance as a medical therapy varies.Fórmula:C6H13NO5·HClPureza:99.77%Cor e Forma:White Solid CrystallinePeso molecular:215.63VTP50469
CAS:VTP50469 is a highly selective and orally active small molecule inhibitor of the Menin-MLL protein-protein interaction.Cost-effective and quality-assured.Fórmula:C32H47FN6O4SPureza:98.31% - 99.55%Cor e Forma:SolidPeso molecular:630.82Minocycline hydrochloride
CAS:Minocycline HCl: tetracycline antibiotic, treats bacterial infections and acne, may cause acute or chronic hepatitis.Fórmula:C23H28ClN3O7Pureza:99.28% - >99.99%Cor e Forma:Bright Yellow-Orange Amorphous Solid Crystalline YellowPeso molecular:493.94MAK683
CAS:MAK683 is an inhibitor of embryonic ectoderm development (EED) (IC50s: 59, 89, 26 nM in EED Alphascreen binding, LC-MS and ELISA assay).Fórmula:C20H17FN6OPureza:98.25% - 99.92%Cor e Forma:SolidPeso molecular:376.39Golidocitinib
CAS:Golidocitinib (AZD4205) is a selective JAK1 inhibitor (IC50: 73 nM) and weakly inhibits JAK2/JAK3 (IC50: >14.7, >30 μM).Fórmula:C25H31N9O2Pureza:98.87% - 99.88%Cor e Forma:SolidPeso molecular:489.57TRIM24/BRPF1-IN-2
CAS:<p>TRIM24/BRPF1-IN-2 is a TRIM24/BRPF1 dual inhibitor with anticancer activity that inhibits the proliferation of prostate cancer cells.</p>Fórmula:C20H22N2O4SPureza:98.69% - 99.13%Cor e Forma:SoildPeso molecular:386.47Uzansertib phosphate
CAS:Uzansertib phosphate (INCB053914 phosphate) is an orally active, ATP-competitive inhibitor of pan-PIM kinase, inhibiting PIM1, PIM2 and PIM3.Fórmula:C26H29F3N5O7PPureza:99.75% - 99.79%Cor e Forma:SolidPeso molecular:611.51ODM-207
CAS:ODM-207 (BET-IN-4) is a potent BRD4 inhibitor.Fórmula:C22H21N3O3Pureza:99.75%Cor e Forma:SolidPeso molecular:375.42Levetiracetam
CAS:Levetiracetam (SIB-S1) is a relatively unique anticonvulsant that is typically used in combination with other antiepileptic medications for partial onsetFórmula:C8H14N2O2Pureza:99.67% - 99.86%Cor e Forma:White Crystalline PowderPeso molecular:170.21BMS-986158
CAS:<p>BMS-986158: BET inhibitor, IC50 of 6.6 nM in SCLC, 5 nM in TNBC cells.</p>Fórmula:C30H33N5O2Pureza:98.78%Cor e Forma:SolidPeso molecular:495.62Oltipraz
CAS:Oltipraz (RP 35972) is a synthetic dithiolethione with potential chemopreventive and anti-angiogenic properties.Fórmula:C8H6N2S3Pureza:98.79% - 99.77%Cor e Forma:SolidPeso molecular:226.34MS402
CAS:MS402 is a novel BD1-selective BET BrD inhibitor.Fórmula:C20H19ClN2O3Pureza:99.72%Cor e Forma:SolidPeso molecular:370.83LIN28 inhibitor LI71
CAS:<p>LIN28 inhibitor LI71 is a potent and cell-permeable LIN28 inhibitor, which abolishes LIN28-mediated oligouridylation with an IC50 of 7 uM.</p>Fórmula:C21H21NO3Pureza:95.88%Cor e Forma:SolidPeso molecular:335.4Lin28-let-7a antagonist 1
CAS:Lin28-let-7a antagonist 1, with an IC50 of 4.03 μM for Lin28A-let-7a-1 interaction，and shows a clear antagonistic effect against the Lin28-let-7a interaction.Fórmula:C31H29N5O7Pureza:99.44%Cor e Forma:SolidPeso molecular:583.59Pulrodemstat benzenesulfonate
CAS:<p>Pulrodemstat benzenesulfonate (CC-90011 benzenesulfonate) is a potent and orally inhibitor of lysine specific demethylase-1 (LSD1) with anticancer effect.</p>Fórmula:C30H29F2N5O5SPureza:97.67%Cor e Forma:SolidPeso molecular:609.64
