Dano de DNA/Reparo de DNA
Os inibidores de dano/ reparo do DNA são compostos que interferem nos processos envolvidos na detecção e reparo de danos ao DNA. Esses inibidores são fundamentais para estudar os mecanismos de estabilidade genômica, mutagênese e resposta ao dano ao DNA. Eles também são importantes na pesquisa do câncer, pois muitos tumores dependem de vias específicas de reparo de DNA para sobreviver. Ao inibir essas vias, os inibidores de dano/reparo de DNA podem aumentar a eficácia da quimioterapia e da radioterapia. Na CymitQuimica, oferecemos uma ampla gama de inibidores de alta qualidade de dano/reparo de DNA para apoiar sua pesquisa em biologia molecular, oncologia e farmacologia.
Subcategorias de "Dano de DNA/Reparo de DNA"
- ATM/ATR(71 produtos)
- Alquilação de DNA(11 produtos)
- DNA Metiltransferase(421 produtos)
- DNA girase(11 produtos)
- DNA-PK(51 produtos)
- MTH1(1 produtos)
- Nucleosídeo Antimetabólito/Análogo(1.388 produtos)
- Transcriptase reversa(43 produtos)
- Sirtuína(88 produtos)
- Telomerase(33 produtos)
- Topoisomerase(136 produtos)
Exibir 3 mais subcategorias
Foram encontrados 957 produtos de "Dano de DNA/Reparo de DNA"
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NSC 370284
CAS:<p>NSC 370284 inhibits STAT3/5, reducing AML cell viability with TET1 overexpression in vitro/in vivo.</p>Fórmula:C21H25NO6Pureza:99.74%Cor e Forma:SolidPeso molecular:387.43PARP1-IN-8
CAS:<p>PARP1-IN-8 (N-(3-chlorophenyl)-3-(1-oxo-4-phenylphthalazin-2(1H)-yl)propanamide) is an effective inhibito of PARP1 (IC50 = 97 nM).</p>Fórmula:C23H18ClN3O2Pureza:99.04%Cor e Forma:SolidPeso molecular:403.86TAK1 inhibitor
CAS:<p>TAK1 inhibitor is an inhibitor, which can inhibit MCF-7, A549, DU-145 and MDA MB-231, with IC50 of 0.021, 0.14, 0.064 and 0.19, respectively.</p>Fórmula:C22H19ClN6O2SPureza:98%Cor e Forma:SoildPeso molecular:466.94Wistin
CAS:<p>Wistin, isolated from Caragana sinica roots, is a PPARα and PPARγ agonist [1] [2] .</p>Fórmula:C23H24O10Cor e Forma:SolidPeso molecular:460.43Suprastat
CAS:<p>Suprastat is an HDAC6 inhibitor used in silico simulations.</p>Pureza:98%Cor e Forma:Solid1-Methyladenosine-d3
<p>1-Methyladenosine-d3 hydrochloride is the hydrochloride salt form of deuterium-labeled 1-Methyladenosine. This compound is a modification of RNA that serves as a biomarker for tumors, with elevated levels in the body linked to cancer development. Upon methylation, 1-Methyladenosine upregulates the expression of PPARδ, regulates cholesterol metabolism, and activates the Hedgehog signaling pathway, thereby driving the onset of liver tumors.</p>Cor e Forma:Odour SolidPyronaridine tetraphosphate
CAS:<p>Pyronaridine tetraphosphate is a DNA topoisomerase 2 inhibitor with antimalarial and antitumor activity for the treatment of P. falciparum infection.</p>Fórmula:C29H44ClN5O18P4Pureza:99.82%Cor e Forma:SolidPeso molecular:910.03TNKS-2-IN-1
CAS:<p>TNKS-2-IN-1 inhibits TNKS1/2 (IC50: 259/1100 nM), has antimicrobial effects on E. coli/S. aureus, and blocks NLRP3/IL-1β release (IC50: 5 μM).</p>Fórmula:C14H9N3O3Pureza:98.34%Cor e Forma:SolidPeso molecular:267.24Banoxantrone (D12)
CAS:<p>Banoxantrone D12, deuterium-labeled version, reduces to AQ4 - a stable DNA-targeting topoisomerase II inhibitor.</p>Fórmula:C22H28N4O6Pureza:98%Cor e Forma:SolidPeso molecular:456.55PR-104 sodium
CAS:<p>PR-104 sodium: hypoxia-activated, tumor-targeting pre-prodrug; turns into PR-104A for research.</p>Fórmula:C14H19BrN4NaO12PSCor e Forma:SolidPeso molecular:601.25ARN24139
<p>ARN24139: a topoisomerase II poison; IC50=7.3μM. Inhibits DU145, HeLa, A549 cell growth; IC50s=4.7, 3.8, 3.1μM.</p>Cor e Forma:SolidWAY-323061
CAS:<p>WAY-323061 is a SIRT2 inhibitor.</p>Fórmula:C25H21N5O2SPureza:99.33%Cor e Forma:SolidPeso molecular:455.53Elomotecan hydrochloride
CAS:<p>Elomotecan hydrochloride (BN 80927), a potent hCPT analog, inhibits topoisomerases I/II, outperforming other anticancer drugs.</p>Fórmula:C29H33Cl2N3O4Cor e Forma:SolidPeso molecular:558.5Leriglitazone
CAS:<p>Leriglitazone, pioglitazone's metabolite, is a PPARγ agonist (Ki:1.2μM, EC50:680nM), enhancing transcription and stabilizing AF-2.</p>Fórmula:C19H20N2O4SPureza:98%Cor e Forma:SolidPeso molecular:372.44PB200
<p>PB200, an HDAC6 inhibitor, demonstrates significant antidepressant effects with an IC50 value of 1.97 nM. It operates by normalizing aberrant HDAC6 expression levels and alleviating neuroinflammation.</p>Fórmula:C17H18FN3O2Cor e Forma:SolidPeso molecular:315.34CA-M11
<p>CA-M11 (compound CA-M11) is capable of entering the liver's bile salt transport system to release Mirin.</p>Fórmula:C34H46N2O6SCor e Forma:SolidPeso molecular:610.80SCR7
CAS:<p>SCR7, a specific DNA Ligase IV inhibitor, blocks nonhomologous end-joining (NHEJ).</p>Fórmula:C18H14N4OSPureza:98%Cor e Forma:SolidPeso molecular:334.4HDAC9-IN-1
<p>HDAC9-IN-1 (Compound 7g) is a potent inhibitor of HDAC9, exhibiting an IC50 of 40 nM. This compound effectively suppresses various human cancer cell lines, induces apoptosis, modulates caspase-related proteins and p38, and results in DNA damage.</p>Fórmula:C27H22N4O3SCor e Forma:SolidPeso molecular:482.55AsCas12a Nuclease
<p>AsCas12a Nuclease is a CRISPR nuclease capable of specifically cleaving double-stranded DNA. It is used in gene editing research.</p>PARP10-IN-3
CAS:<p>PARP10-IN-3: selective inhibitor for mono-ADP-ribotransferase PARP10 (IC50: 480nM), also affects PARP2 and PARP15 (IC50: 1.7μM).</p>Fórmula:C14H12N2O3Pureza:99.41%Cor e Forma:SoildPeso molecular:256.26DNA Damage & Repair Compound Library
<p>A unique collection of xnum DNA Damage &amp; Repair related compounds for high throughput screening (HTS) and high content screening (HCS);</p>Cor e Forma:Odour SolidGimatecan HCl
<p>Gimatecan HCl (ST1481 HCL) is a potent topoisomerase I inhibitor. Gimatecan is an orally bioavailable camptothecin analogue with antitumor activity.</p>Fórmula:C25H26ClN3O5Pureza:97.04%Cor e Forma:SoildPeso molecular:483.9423-epi-26-Deoxyactein
CAS:<p>23-epi-26-Deoxyactein is a naturally occurring compound exhibiting anti-obesity and anti-cancer properties when administered orally [1] [2] [3].</p>Fórmula:C37H56O10Cor e Forma:SolidPeso molecular:660.83Lucidin primeveroside
CAS:<p>Lucidin primeveroside (Lucidin 3-O-primeveroside) is a natural product isolated from the root powder of akane (Rubia akane) and can be used as a coloring agent</p>Fórmula:C26H28O14Pureza:98%Cor e Forma:SolidPeso molecular:564.49DMT-dU-CE Phosphoramidite
CAS:<p>DMT-dU-CE Phosphoramidite is a nucleoside molecule commonly used for the synthesis and sequencing of DNA.</p>Fórmula:C39H47N4O8PPureza:99.55%Cor e Forma:SolidPeso molecular:730.79Tibesaikosaponin V
CAS:<p>TKV, a triterpene diglycoside from Bupleurum chinense, curbs lipid build-up and fat content in adipocytes without harm and hinders fat cell differentiation.</p>Fórmula:C42H68O15Cor e Forma:SolidPeso molecular:812.98Dichlorogelignate
CAS:<p>Dichlorogelignate (compound 4) acts as a selective inhibitor of topoisomerase II (Topo II), achieving 100% inhibition at 50 μM [1].</p>Fórmula:C32H34O18Cor e Forma:SolidPeso molecular:706.6Ketopioglitazone
CAS:<p>Ketopioglitazone is an active metabolite of pioglitazone.</p>Fórmula:C19H18N2O4SCor e Forma:SolidPeso molecular:370.42PNU-142586
CAS:<p>PNU-142586 is a bio-active chemical.</p>Fórmula:C16H20FN3O6Cor e Forma:SolidPeso molecular:369.34MST-312
CAS:<p>MST-312, a telomerase inhibitor derived from green tea's EGCG, has research potential in cancer, including MM.</p>Fórmula:C20H16N2O6Pureza:99.61% - 99.68%Cor e Forma:SolidPeso molecular:380.35Anti-obesity agent 1
<p>Compound 4 (Anti-obesity agent 1) demonstrates potential for enhanced lipolysis, highlighting its anti-obesity characteristics.</p>Fórmula:C21H22N2O6Cor e Forma:SolidPeso molecular:398.409HDAC3/8 ligand-1
<p>HDAC3/8 ligand-1 (compound 40) serves as a ligand for the target protein of PROTAC, utilized in the synthesis of YX968.</p>Fórmula:C14H22N4OCor e Forma:SolidPeso molecular:262.35CH-0793076
CAS:<p>CH-0793076: hexacyclic camptothecin, TP300 metabolite, targets BCRP, inhibits DNA topo I (IC50: 2.3 μM).</p>Fórmula:C26H26N4O4Pureza:98%Cor e Forma:SolidPeso molecular:458.51SMPB Crosslinker
CAS:<p>SMPB crosslinker reacts with sulfhydryl/amino groups, has a longer chain than MBS, and a non-cleavable spacer arm.</p>Fórmula:C18H16N2O6Pureza:98%Cor e Forma:SolidPeso molecular:356.3315-LOX-IN-2
<p>15-LOX-IN-2 (Compound 2a) is an orally active inhibitor of COX-2/15-LOX and a partial agonist of PPARγ. It exhibits anti-inflammatory activity by inhibiting levels of 20-HETE, IL-1β, and TNF-α in LPS-treated RAW 264.7 cells. Additionally, it significantly enhances glucose uptake without the presence of insulin and is applicable in metabolic disease research.</p>Cor e Forma:Odour Solid20-carboxy Arachidonic Acid
CAS:<p>20-COOH-AA, 20-HETE metabolite, inhibits kidney ion transport, relaxes constricted vessels, and activates PPARα/γ.</p>Fórmula:C20H30O4Cor e Forma:SolidPeso molecular:334.456Benzamide, 3-methoxy-N-(3-thiazolo[5,4-b]pyridin-2-ylphenyl)
CAS:<p>3-Methoxybenzamide derivative modulates sirtuins; may boost cell lifespan and treat diseases.</p>Fórmula:C20H15N3O2SPureza:99.32%Cor e Forma:SolidPeso molecular:361.42PARP1-IN-33
CAS:<p>PARP1-IN-33 (Example 6) is a PARP1 inhibitor with an IC50 of 0.41 nM. It demonstrates protective effects on retinal cells, exhibiting an EC50 of 0.02 nM in inhibiting hydrogen peroxide-induced MTS activity in human retinal pigment epithelial cells.</p>Fórmula:C23H24ClFN4OCor e Forma:SolidPeso molecular:426.91SpCas9 D10A Nickase
<p>SpCas9 D10A Nickase is a variant of the Cas9 protein. This mutation retains the functionality of one cleavage domain of the Cas9 nuclease, allowing it to specifically nick a target single strand. Additionally, SpCas9 D10A Nickase is effective in reducing off-target effects.</p>HDAC-IN-78
<p>HDAC-IN-78 (compound 66a) is an HDAC inhibitor utilized for cancer research.</p>Cor e Forma:Odour SolidnTZDpa
CAS:<p>nTZDpa is an antibiotic with antimicrobial activity.</p>Fórmula:C22H15Cl2NO2SCor e Forma:SolidPeso molecular:428.33DNMT1/HDAC-IN-1
<p>DNMT1/HDAC-IN-1 (compound (R)-23a), a potent dual inhibitor targeting both DNMT1 and HDAC, exhibits impressive inhibitory effects specifically on HDAC1 (HDAC1:IC50=0.05 μM), a major HDAC isoform that interacts with DNMT1 across multiple protein complexes involved in the transcriptional silencing of TSGs. This compound has been shown to remodel the tumor immune microenvironment and induce tumor regression, effectively reversing cancer-specific epigenetic abnormalities.</p>Cor e Forma:Odour SolidDB1255 2TFA
<p>DB1255 2TFA is an ERG/DNA binding inhibitor with an unusual and potent monomer binding pattern at the minor groove site for the study of genetic disorders.</p>Fórmula:C26H20F6N4O4S2Pureza:98.32%Cor e Forma:SolidPeso molecular:630.58Elomotecan
CAS:<p>Elomotecan (BN 80927 free base) is a potent inhibitor of topoisomerases I and II.Cost-effective and quality-assured.</p>Fórmula:C29H32ClN3O4Cor e Forma:SolidPeso molecular:522.04ATM Inhibitor-9
<p>ATM Inhibitor-9 (Compd 7a) is a potent inhibitor of ATM kinase, exhibiting an IC50 value of 5 nM, and is utilized in cancer research [1].</p>Fórmula:C25H32N6O2Pureza:98%Cor e Forma:SolidPeso molecular:448.56Cytidine 5'-diphosphate trisodium salt
CAS:<p>CDP, a trisodium salt, helps synthesize DNA/RNA by aiding phosphoryl transfer from ATP to CMP via UMPK.</p>Fórmula:C9H15N3Na3O11P2Pureza:99.55%Cor e Forma:White Crystalline PowderPeso molecular:472.15SIRT-IN-5
<p>SIRT-IN-5, a selective inhibitor of SIRT3 with an IC50 of 2.88 μM, facilitates the differentiation of multiple myeloma cells. This differentiation is associated with increased expression of the differentiation antigens CD49e and human immunoglobulin light chains λ and κ.</p>Cor e Forma:Odour SolidChimmitecan
CAS:<p>Chimmitecan ((S)-9-Allyl-10-hydroxycamptothecin) is a potent inhibitor of topoisomerase I and displays outstanding activity in vitro and in vivo.</p>Fórmula:C23H20N2O5Pureza:98.35%Cor e Forma:SoildPeso molecular:404.42Becatecarin
CAS:<p>Becatecarin, water-soluble and anti-cancer, inhibits topoisomerases I/II and induces DNA cleavage and apoptosis; has myelosuppressive effects; ABCG2 substrate.</p>Fórmula:C33H34Cl2N4O7Cor e Forma:SolidPeso molecular:669.56IC 86621
CAS:<p>IC 86621: DNA-PK ATP-competitive inhibitor, IC50 120 nM, enhances DSB antitumor effects, EC50 68 µM for repair.</p>Fórmula:C12H15NO3Pureza:99.68%Cor e Forma:SolidPeso molecular:221.25GSK3735967
CAS:<p>GSK3735967: DNMT1 inhibitor, IC50 40 nM, dicyanopyridine core, binds hemimethylated CpG, interacts with H4K20me3.</p>Fórmula:C25H31N7OSCor e Forma:SolidPeso molecular:477.62Phosphoramide mustard
CAS:<p>Phosphoramide mustard is a toxic metabolite of cyclophosphamide with anticancer activity and ovarian toxicity that induces DNA damage.</p>Fórmula:C4H11Cl2N2O2PPureza:93.00%Cor e Forma:SolidPeso molecular:221.02MS9024
<p>MS9024 is a degrader of DNA methyltransferase 1 (DNMT1), facilitating its degradation in HCT116 cells via the ubiquitin-proteasome pathway, with a DC50 of 35 nM (DC50 values are 254 nM in MDA-MB-468 and 101 nM in H1299). Additionally, MS9024 inhibits DNMT1 with an IC50 of 0.43 μM.</p>Cor e Forma:Odour SolidCarboxy-pyridostatin 2HCl
<p>Carboxy-pyridostatin 2HCl has potential antitumor activity with high affinity for DNA at DNA G4s.</p>Fórmula:C35H36Cl2N10O7Pureza:97.12% - 99.10%Cor e Forma:SoildPeso molecular:779.63TUG-499
CAS:<p>TUG-499 is a selective free fatty acid receptor 1 (FFAR1 or GPR40) agonist (EC50: 7.39).TUG-499 has an affinity for FFAR1 or GPR40 over the related receptors</p>Fórmula:C16H11Cl2NO2Pureza:99.93%Cor e Forma:SoildPeso molecular:320.17Colibactin 742
CAS:<p>Colibactin 742, a stable derivative of colibactin, efficiently induces DNA interstrand cross-links, activates the Fanconi Anemia DNA repair pathway, and leads</p>Fórmula:C37H42N8O5S2Cor e Forma:SolidPeso molecular:742.91MPT0B390
CAS:<p>MPT0B390 is an inhibitor of HDAC and a TIMP3 inducer inhibiting tumor growth, metastasis, and angiogenesis.</p>Fórmula:C17H17N3O5SPureza:99.4%Cor e Forma:SolidPeso molecular:375.4GpC Methyltransferase
<p>GpC Methyltransferase (GpC) is an enzyme that methylates DNA, specifically targeting cytosine residues within GpC dinucleotides of non-nucleosomal DNA in vitro.</p>Stearolic acid
CAS:<p>Stearolic acid is a useful organic compound for research related to life sciences. The catalog number is T124753 and the CAS number is 506-24-1.</p>Fórmula:C18H32O2Cor e Forma:SolidPeso molecular:280.452Gancaonin L
CAS:<p>Gancaonin L is a natural product that can be used as a reference standard. The CAS number of Gancaonin L is 129145-50-2.</p>Fórmula:C20H18O6Cor e Forma:SolidPeso molecular:354.3589-Hydroxyellipticin free base
CAS:<p>9-hydroxyellipticine is a potent cytotoxic and antitumor agent. 9-hydroxyellipticine is a 9-hydroxy derivative of ellipticine.</p>Fórmula:C17H14N2OCor e Forma:SolidPeso molecular:262.312'-Deoxy-2'-fluoro-β-D-arabinocytidine hydrochloride
CAS:<p>2'-Deoxy-2'-fluoro-beta-D-arabinocytidine HCl inhibits DNA methyltransferase with potential anti-tumor properties.</p>Fórmula:C9H13ClFN3O4Pureza:99.69%Cor e Forma:SolidPeso molecular:281.67O6BTG-octylglucoside
CAS:<p>O6BTG-octylglucoside is a potent O6-methylguanine-DNAmethyl-transferase (MGMT) inhibitor (IC50s: 10 nM and 32 nM in HeLa S3 cells and in vitro (cell extracts)).</p>Fórmula:C24H34BrN5O7SPureza:98%Cor e Forma:SolidPeso molecular:616.53Heptaplatin
CAS:<p>Heptaplatin, an anticancer platinum compound, counters many cancers, including cisplatin-resistant types, with a 17% response rate and tolerable toxicity.</p>Fórmula:C11H20N2O6PtCor e Forma:White Crystalline PowderPeso molecular:471.36SIRT5 inhibitor 3
CAS:<p>SIRT5 inhibitor 3 is potent and competitive by inhibiting SIRT5 deacetylation, with potential in metabolic, cancer, neurodegenerative, cardiovascular .</p>Fórmula:C22H12FN3O4Pureza:98%Cor e Forma:SolidPeso molecular:401.35Phosphoramide mustard cyclohexanamine
CAS:<p>Phosphoramide mustard cyclohexanamine is active metabolite of cyclophosphamide, an alkylating agent that cross-links DNA strands,causes cell death, antitumor.</p>Fórmula:C10H24Cl2N3O2PPureza:95%Cor e Forma:SolidPeso molecular:320.2(R)-GSK-3685032
CAS:<p>(R)-GSK-3685032 is a selective, reversible DNMT1 inhibitor, non-covalent, IC50: 0.036 μM; reduces DNA methylation, inhibits cancer growth.</p>Fórmula:C22H24N6OSCor e Forma:SolidPeso molecular:420.54(4-NH2)-Exatecan
CAS:<p>(4-NH2)-Exatecan is a topoisomerase inhibitor with potential anticancer activity for the synthesis of antibody drug conjugates (ADCs).</p>Fórmula:C23H21N3O4Pureza:99.89%Cor e Forma:SolidPeso molecular:403.43BRD7586
CAS:<p>BRD7586 is a cell-permeable small molecule inhibitor of SpCas9 that enhances SpCas9 specificity.</p>Fórmula:C17H14ClN3O3S2Pureza:97.70% - 99.03%Cor e Forma:SolidPeso molecular:407.89VK-1727
<p>VK-1727 inhibits EBNA1 DNA binding, reducing proliferation of EBV-positive cells while sparing EBV-negative cells, useful for multiple sclerosis research.</p>Fórmula:C29H25NO4Pureza:98.074%Cor e Forma:SolidPeso molecular:451.51Banoxantrone dihydrochloride
CAS:<p>Banoxantrone dihydrochloride (AQ4N dihydrochloride) is a novel hypoxic cytotoxin that selectively kills hypoxic cells through an iNOS-dependent mechanism.</p>Fórmula:C22H30Cl2N4O6Pureza:99.88%Cor e Forma:SolidPeso molecular:517.4Gepotidacin
CAS:<p>Gepotidacin is a triazaacenaphthylene antibacterial inhibiting bacterial type II topoisomerase with lower resistance potential than fluoroquinolones.</p>Fórmula:C24H28N6O3Pureza:99.88%Cor e Forma:SolidPeso molecular:448.52HDAC-IN-4
CAS:<p>HDAC-IN-4 is a selective HDAC6 and HDAC10 inhibitor (pIC50s: 7.2 and 6.8 in BRET assay) with antitumoral activity.</p>Fórmula:C20H21N3O2Cor e Forma:SolidPeso molecular:335.45'-O-(4,4'-Dimethoxytrityl)-2'-deoxyuridine
CAS:<p>5'-O-DMT-dU, a dUTPase inhibitor (Ki > 1 mM) for E. coli, is used in DNA synthesis.</p>Fórmula:C30H30N2O7Cor e Forma:SolidPeso molecular:530.57Gatifloxacin mesylate
CAS:<p>Gatifloxacin mesylate, a 4th-gen fluoroquinolone antibiotic, inhibits DNA gyrase and topoisomerase IV.</p>Fórmula:C20H26FN3O7SPureza:98%Cor e Forma:SolidPeso molecular:471.5AMA-37
CAS:<p>AMA-37 is a selective, reversible, and ATP-competitive DNA-PK inhibitor.</p>Fórmula:C17H17NO3Pureza:98%Cor e Forma:SolidPeso molecular:283.32Daun02
CAS:<p>Daun02 is the topoisomerase inhibitor Daunorubicin prodrug.</p>Fórmula:C41H44N2O20Pureza:98%Cor e Forma:SolidPeso molecular:884.79RPR121056
CAS:<p>RPR121056 is a Irinotecan metabolite, which is generated by CYP3A4. Irinotecan is an antineoplastic agent that inhibits topoisomerase type I.</p>Fórmula:C33H38N4O8Pureza:98%Cor e Forma:SolidPeso molecular:618.68Gatifloxacin sesquihydrate
CAS:<p>Gatifloxacin sesquihydrate, a bacterial DNA gyrase inhibitor, is used to treat tuberculosis and pneumonia.</p>Fórmula:C19H24FN3O5Cor e Forma:SolidPeso molecular:393.41Methyl methanesulfonate (Standard)
CAS:<p>Methyl methanesulfonate (Standard) is a standard material used in the analysis of methyl methanesulfonate, typically referenced in its research and analysis.</p>Fórmula:C2H6O3SCor e Forma:SolidPeso molecular:110.13(R)-(+)-Bay-K-8644
CAS:<p>(R)-(+)-Bay-K-8644, a Ca2+ channel agonist, is a dihydropyridine agonist that induces central respiratory depression and inhibits platelet activation in cats.</p>Fórmula:C16H15F3N2O4Pureza:96.51% - 96.51%Cor e Forma:SolidPeso molecular:356.3Telomerase-IN-3
CAS:<p>Telomerase-IN-3 is an inhibitor of telomerase.</p>Fórmula:C19H16ClN5O3Pureza:98%Cor e Forma:SolidPeso molecular:397.82CP-868388 free base
CAS:<p>CP-868388 free base (CP-868388) is a PPARα agonist with hypolipidemic and anti-inflammatory activity and is used in the study of dyslipidemia.</p>Fórmula:C26H33NO5Pureza:99.84%Cor e Forma:SolidPeso molecular:439.54Epitalon
CAS:<p>Epithalon (also known as Epitalon or Epithalone) is the synthetic version of the polypeptide Epithalamin which is naturally produced in the pineal gland.</p>Fórmula:C14H22N4O9Pureza:98%Cor e Forma:SolidPeso molecular:390.35Balaglitazone
CAS:<p>Balaglitazone is a PPARγ agonist that regulates blood glucose and is used in studies of heart failure and myocardial infarction.</p>Fórmula:C20H17N3O4SPureza:99.74%Cor e Forma:SolidPeso molecular:395.43Succinic acid sodium
CAS:<p>Succinic acid sodium is an orally active anxiolytic.</p>Fórmula:C4H6O4·xNaCor e Forma:SolidBRD7116
CAS:<p>BRD7116 competitively binds to bacterial DNA gyrase, with cell-non-autonomous anti-leukemia activity.</p>Fórmula:C28H36N2O4SPureza:99.69% - 99.91%Cor e Forma:SolidPeso molecular:496.66PTGR2-IN-1
CAS:<p>PTGR2-IN-1 is a potent inhibito of PTGR2r. PTGR2-IN-1 increases 15-keto-PGE2-dependent PPARγ transcriptional activity in PTGR2-transfected HEK293T cells.</p>Fórmula:C19H22N2O2Pureza:99.13%Cor e Forma:SolidPeso molecular:310.39YK-3-237
CAS:<p>YK-3-237 (B-[2-Methoxy-5-[(1E)-3-oxo-3-(3,4,5-trimethoxyphenyl)-1-propen-1-yl]phenyl]boronic acid) reduces acetylation of mtp53 and exhibits anti-proliferative</p>Fórmula:C19H21BO7Pureza:99.47%Cor e Forma:SolidPeso molecular:372.18Pamiparib
CAS:<p>Pamiparib (BGB-290) is an orally active, potent, highly selective PARP inhibitor. It has potent PARP trapping, and capability to penetrate the brain.</p>Fórmula:C16H15FN4OPureza:99.69%Cor e Forma:SolidPeso molecular:298.31Pixantrone dimaleate
CAS:<p>Pixantrone dimaleate (Pixantrone Maleate) (BBR 2778 dimaleate) is an experimental antineoplastic drug.</p>Fórmula:C25H27N5O10Pureza:98.70% - 99.11%Cor e Forma:SolidPeso molecular:557.21FIT-039
CAS:<p>FIT-039 is a selective and ATP-competitive, orally active inhibitor of CDK9( IC50 : 5.8 μM;CDK9/cyclin T1).</p>Fórmula:C17H18FN3SPureza:98.61%Cor e Forma:SolidPeso molecular:315.41MC1568
CAS:<p>MC1568 is a specific HDAC inhibitor for maize HD1-A (IC50: 100 nM, in a cell-free assay). It is 34-fold more selective for HD1-A than HD1-B.</p>Fórmula:C17H15FN2O3Pureza:89.82% - ≥95%Cor e Forma:SolidPeso molecular:314.31BYK204165
CAS:<p>BYK204165 (RT-017290) is a potent PARP inhibitor (PARP1; IC50 = 44.67 nM for human recombinant PARP1 in an enzyme assay)</p>Fórmula:C15H12N2O2Pureza:99.61%Cor e Forma:SolidPeso molecular:252.27Niraparib
CAS:<p>Niraparib (MK-4827) inhibits PARP1/PARP2 (IC50: 3.8/2.1 nM), effective on BRCA mutant cancers, 330x less effective on PARP3, V-PARP, Tank1.</p>Fórmula:C19H20N4OPureza:98% - 99.91%Cor e Forma:SolidPeso molecular:320.39AK-7
CAS:<p>AK-7 is a brain-permeable SIRT2 inhibitor and to characterize its cholesterol-reducing properties in neuronal models with an IC50 of 15.5 μM.</p>Fórmula:C19H21BrN2O3SPureza:98.43% - 99.34%Cor e Forma:SolidPeso molecular:437.35Ciprofloxacin hydrochloride monohydrate
CAS:<p>Ciprofloxacin hydrochloride monohydrate (Bay-09867 hydrochloride monohydrate) is a fluoroquinolone antibiotic with potent antibacterial activity.</p>Fórmula:C17H21ClFN3O4Pureza:99.23% - 99.85%Cor e Forma:White Or Yellowish Crystalline PowderPeso molecular:385.82Remetinostat
CAS:<p>Remetinostat (SHP-141), a hydroxamic acid-based inhibitor of histone deacetylase enzymes, is currently being developed for the treatment of cutaneous T-cell</p>Fórmula:C16H21NO6Pureza:98.67%Cor e Forma:SolidPeso molecular:323.34PJ34
CAS:<p>PJ34 HCl is the hydrochloride salt of PJ34, which is a PARP inhibitor with EC50 of 20 nM and is equally potent to PARP1/2.</p>Fórmula:C17H17N3O2Pureza:95.05% - 99.85%Cor e Forma:SolidPeso molecular:295.34Resminostat hydrochloride
CAS:<p>Resminostat hydrochloride (RAS2410 hydrochloride) is an effective inhibitor of HDAC1/HDAC3/HDAC6 (IC50: 42.5/50.1/71.8 nM), respectively, and shows less potent</p>Fórmula:C16H20ClN3O4SPureza:97.63% - 99.68%Cor e Forma:SolidPeso molecular:385.86L67
CAS:<p>L67 (DNA Ligase Inhibitor) is a competitive human DNA ligase inhibitor, inhibits DNA ligases I and III (IC50: 10 μM).</p>Fórmula:C16H14Br2N4O4Pureza:98.34% - 99.56%Cor e Forma:SolidPeso molecular:486.11Fluzoparib
CAS:<p>Fluzoparib (SHR3162) is a novel, potent, and orally available inhibitor of PARP, potentially for the treatment of solid tumours.</p>Fórmula:C22H16F4N6O2Pureza:98.53% - 99.63%Cor e Forma:SolidPeso molecular:472.4SRT1720 hydrochloride
CAS:<p>SRT1720 hydrochloride (SRT1720 HCl) is a selective activator of SIRT1 (EC1.5: 0.16 μM) and shows less potent activities on SIRT2/SIRT3 (EC1.5s: 37 μM/300 μM).</p>Fórmula:C25H24ClN7OSPureza:98% - 99.93%Cor e Forma:SolidPeso molecular:506.22Pyridostatin TFA
CAS:<p>Pyridostatin Trifluoroacetate Salt is a G-quadruplexe stabilizer with Kd of 490 nM in a cell-free assay, which targets a series of proto-oncogenes including c-</p>Fórmula:C37H35F9N8O11Pureza:97.09% - 99.84%Cor e Forma:SolidPeso molecular:938.71Suramin Sodium Salt
CAS:<p>Suramin Sodium Salt (BAY-205) is a polysulphonated naphthylurea with potential antineoplastic activity. Suramin blocks the binding of various growth factors.</p>Fórmula:C51H34N6Na6O23S6Pureza:97.47% - 99.97%Cor e Forma:WhitePeso molecular:1429.15Darglitazone Sodium
CAS:<p>Darglitazone Sodium, an oral PPAR-γ agonist, aids type II diabetes study by regulating glucose and lipids.</p>Fórmula:C23H21N2NaO4SCor e Forma:SolidPeso molecular:444.48BGP-15
CAS:<p>BGP-15 (BGP-15 2HCl) is a PARP inhibitor with protecting effect after ischemia-reperfusion injury.</p>Fórmula:C14H24Cl2N4O2Pureza:98.17% - 99.89%Cor e Forma:SolidPeso molecular:351.27Citarinostat
CAS:<p>ACY-241 (Citarinostat), a potent oral HDAC inhibitor, may induce tumor cell death and block growth by altering gene expression.</p>Fórmula:C24H26ClN5O3Pureza:98.06% - 99.06%Cor e Forma:SolidPeso molecular:467.95Bisantrene
CAS:<p>Bisantrene, an anthracene derivative, targets DNA causing breaks and replication inhibition; it's like doxorubicin minus the cardiotoxicity.</p>Fórmula:C22H22N8Pureza:96.07% - 98.57%Cor e Forma:SolidPeso molecular:398.46RHPS4
CAS:<p>RHPS4 (RHPS 4 methosulfate) is a potent inhibitor of Telomerase at submicromolar.</p>Fórmula:C22H17F2N2·CH3O4SPureza:99.72%Cor e Forma:SolidPeso molecular:458.48Thiacloprid
CAS:<p>Thiacloprid: insecticide targeting insect nAChRs, IC50 - Drosophila: 2.7 nM, Mouse α4β2 nAChRs: 860 nM.</p>Fórmula:C10H9ClN4SPureza:98.66% - 99.95%Cor e Forma:Yellowish Crystalline PowderPeso molecular:252.72Rabdosiin
CAS:<p>Rabdosiin ((+)-Rabdosiin) is a natural product, and has anti-allergic activity, anti-HIV activity and inhibition on DNA topoisomerase.</p>Fórmula:C36H30O16Pureza:98.64% - 99.49%Cor e Forma:SolidPeso molecular:718.61PIK-75 hydrochloride
CAS:<p>PIK-75 hydrochloride (PIK-75 HCl) is a p110α inhibitor, isoform-specific mutants at Ser773, and potently inhibits DNA-PK with IC50 of 2 nM in cell-free assay.</p>Fórmula:C16H14BrN5O4S·HClPureza:97.82%Cor e Forma:SolidPeso molecular:488.74Pentamidine dihydrochloride
CAS:<p>Pentamidine dihydrochloride (MP-601205 dihydrochloride) is an aromatic diamidine agent with activity against a number of microorganisms including protozoa (</p>Fórmula:C19H26Cl2N4O2Pureza:99.80%Cor e Forma:SolidPeso molecular:413.34JW 55
CAS:<p>JW 55 (JW55) is an effective and selective β-catenin signaling pathway inhibitor, works by inhibition of the PARP domain of tankyrase 1 and tankyrase 2 (TNKS1/2</p>Fórmula:C25H26N2O5Pureza:99.31% - 99.76%Cor e Forma:SolidPeso molecular:434.48Tretazicar
CAS:<p>CB1954, an anticancer prodrug, turns into a potent alkylating agent when activated by NQO2 and EP-0152R.</p>Fórmula:C9H8N4O5Pureza:99.41% - 99.7%Cor e Forma:SolidPeso molecular:252.18Coralyne chloride
CAS:<p>Coralyne chloride is a protoberberine with strong anticancer activity.</p>Fórmula:C22H22ClNO4Pureza:98.88%Cor e Forma:SolidPeso molecular:399.87Adenine hemisulfate
CAS:<p>Adenine hemisulfate (Diadenine sulphate) is a sulfate salt form of adenine which is a purine derivative and a nucleobase with a variety of roles in biochemistry</p>Fórmula:(C5H5N5)·H2SO4Pureza:99.48%Cor e Forma:White To Light Yellow Crystal PowderPeso molecular:368.33Selisistat S-enantiomer
CAS:<p>Selisistat S-enantiomer (EX-527 S-enantiomer) is an effective and specific SIRT1 inhibitor (IC50 = 98 nM) and shows >200-fold selectivity against SIRT2/3.</p>Fórmula:C13H13ClN2OPureza:99.86%Cor e Forma:SolidPeso molecular:248.71AZD 6482
CAS:<p>AZD 6482 (KIN-193) is a potent and selective inhibitor of p110β and PI3Kβ with IC50 values of 0.69nM and 10nM.Cost-effective and quality-assured.</p>Fórmula:C22H24N4O4Pureza:99.79% - 99.95%Cor e Forma:SolidPeso molecular:408.45NPC 15199
CAS:<p>NPC 15199 (FMOC-L-Leucine) is an anti-inflammatory agent.</p>Fórmula:C21H23NO4Pureza:99.93% - 99.94%Cor e Forma:White Crystalline PowderPeso molecular:353.41Genz-644282
CAS:<p>Genz-644282, a novel non-camptothecin topoisomerase I inhibitor for cancer treatment.</p>Fórmula:C22H21N3O5Pureza:97.49%Cor e Forma:SolidPeso molecular:407.42Pentamidine
CAS:<p>Pentamidine is an antifungal and antiprotozoal agent, interacting directly with the pathogen genome by binding to AT-rich regions of duplex DNA and the minor</p>Fórmula:C19H24N4O2Pureza:98.64% - 99.67%Cor e Forma:Crystallizes As Colorless Plates From Water SolidPeso molecular:340.42AG-494
CAS:<p>AG-494 (Tyrphostin B48) is an inhibitor of epidermal growth factor receptor kinase.</p>Fórmula:C16H12N2O3Pureza:98.69%Cor e Forma:SolidPeso molecular:280.28TIQ-A
CAS:<p>TIQ-A blocks PARP1 to prevent excessive DNA damage response, implicated in ischemia, asthma, and atherosclerosis.</p>Fórmula:C11H7NOSPureza:99.75%Cor e Forma:SolidPeso molecular:201.24AZD-2461
CAS:<p>AZD2461 is a novel PARP inhibitor.</p>Fórmula:C22H22FN3O3Pureza:98% - 99.87%Cor e Forma:SolidPeso molecular:395.43Clofibrate
CAS:<p>Clofibrate (Clofibrato) is an aryloxyisobutyric acid derivate with antihyperlipidemic activity.</p>Fórmula:C12H15ClO3Pureza:98.77%Cor e Forma:Oil LiquidPeso molecular:242.70Pyridostatin
CAS:<p>Pyridostatin (RR82) is a synthetic small-molecule stabilizer of G-quadruplexes, a secondary structure of DNA that usually exists in the end of the chromosome or</p>Fórmula:C31H32N8O5Pureza:98%Cor e Forma:SolidPeso molecular:596.64TMPyP4 tosylate
CAS:<p>TMPyP4 tosylate (TMP 1363) is a quadruplex-specific ligand and is a telomerase inhibitor with antitumor effects in osteosarcoma cell lines.</p>Fórmula:C72H66N8O12S4Pureza:98.61% - 99.85%Cor e Forma:SolidPeso molecular:1363.6UPF 1069
CAS:<p>UPF 1069 is a specific PARP2 inhibitor ( IC50: 0.3 μM). It is ~27-fold selective against PARP1.</p>Fórmula:C17H13NO3Pureza:98.80% - 99.88%Cor e Forma:SolidPeso molecular:279.29KU-57788
CAS:<p>NU7441 (KU-57788 (NU7441)) is a highly effective and specific DNA-PK inhibitor (IC50: 14 nM).</p>Fórmula:C25H19NO3SPureza:98% - >99.99%Cor e Forma:SolidPeso molecular:413.49EDO-S101
CAS:<p>EDO-S101 (Tinostamustine) is a pan HDAC inhibitor with IC50 values of 9, 9 and 25 nM for HDAC1, HDAC2 and HDAC3 , respectively.</p>Fórmula:C19H28Cl2N4O2Pureza:98.02% - 99.44%Cor e Forma:SolidPeso molecular:415.36PI3K-IN-1
CAS:<p>PI3K-IN-1 (Voxtalisib Analogue) is a dual inhibitor of mTOR/PI3K, mostly for p110γ , also inhibits DNA-PK and mTOR.</p>Fórmula:C31H29N5O6SPureza:97.03% - 98%Cor e Forma:SolidPeso molecular:599.66RK-287107
CAS:<p>RK-287107 is an effective and specific inhibitor of tankyrase (IC50s: 14.3 and 10.6 nM for tankyrase-1 and tankyrase-2, respectively).</p>Fórmula:C22H26F2N4O2Pureza:99.64%Cor e Forma:SolidPeso molecular:416.46SCR130
CAS:<p>SCR130 (1,7,9-Triazaspiro[4.5]dec-1-ene-6,10-dione, 2,4-bis(4-chlorophenyl)-8-thioxo-) 是基于 SCR7 的 DNA 非同源末端连接抑制剂，可诱导细胞凋亡并，具有抗癌活性。 它特异性依赖连接酶 IV，抑制 DNA 的末端连接。</p>Fórmula:C19H13Cl2N3O2SPureza:98.9%Cor e Forma:SolidPeso molecular:418.3PARP1-IN-5 dihydrochloride
CAS:<p>PARP1-IN-5 dihydrochloride: oral, potent PARP-1 inhibitor (IC50=14.7 nM), for cancer research.</p>Fórmula:C25H26Cl2N2O5SPureza:98.01%Cor e Forma:SolidPeso molecular:537.46OUL35
CAS:<p>OUL35 (NSC-39047) is a selective PARP-10 inhibitor, and small-molecule ARTD10 inhibitor. OUL35 has been shown to rescue cells from ARTD10-induced cell death.</p>Fórmula:C14H12N2O3Pureza:99.2%Cor e Forma:SolidPeso molecular:256.26Furegrelate
CAS:<p>FUREGRELATE, a thromboxane A2 (TxA2) synthase inhibitor, blunts the development of pulmonary arterial hypertension in neonatal piglets.</p>Fórmula:C15H11NO3Pureza:99.71%Cor e Forma:SolidPeso molecular:253.25AZ32
CAS:<p>AZ32 is an orally bioavailable and blood-brain barrier-penetrating ATM inhibitor with an IC50 of <6.2 nM for ATM enzyme, and an IC50 of 0.31 μM for ATM in cell.</p>Fórmula:C20H16N4OPureza:98.68% - 99.68%Cor e Forma:SolidPeso molecular:328.37AZ9482
CAS:<p>AZ9482, a potent PARP inhibitor with 2-piperazinyl-3-cyano-pyridine linkage, causes centrosome declustering in HeLa cells with an EC50 < 18 nM.</p>Fórmula:C26H22N6O2Pureza:99.18% - 99.86%Cor e Forma:SolidPeso molecular:450.49DR2313
CAS:<p>DR2313 is a competitive inhibitor of poly(ADP-ribose) polymerase (IC50: 0.20 and 0.24 μM for PARP-1 and PARP-2 respectively). It also has neuroprotective.</p>Fórmula:C8H10N2OSPureza:98.65%Cor e Forma:SolidPeso molecular:182.24VAL-083
CAS:<p>VAL-083 (Dianhydrogalactitol) is an alkylating compound that creates N7 methylation on DNA. It also has antitumor activity.</p>Fórmula:C6H10O4Pureza:97.94%Cor e Forma:SolidPeso molecular:146.14E7449
CAS:<p>E7449 is a potent inhibitor of PARP1, PARP2, TNKS1, and TNKS2 with IC50s of 2, 1, ~50, and ~50 nM respectively.</p>Fórmula:C18H15N5OPureza:97.13%Cor e Forma:SolidPeso molecular:317.34Pixantrone hydrochloride
CAS:<p>Pixantrone hydrochloride is a topoisomerase II inhibitor and DNA intercalator with anti-tumor properties.</p>Fórmula:C17H20ClN5O2Cor e Forma:SolidPeso molecular:361.83Methotrexate disodium
CAS:<p>Methotrexate disodium is an tetrahydrofolate dehydrogenase inhibitor</p>Fórmula:C20H20N8Na2O5Pureza:99.77% - 99.96%Cor e Forma:SolidPeso molecular:498.4NKL 22
CAS:<p>NKL 22 (Histone Deacetylase Inhibitor IV) is an effective Histone Deacetylase Inhibitor.</p>Fórmula:C19H23N3O2Pureza:96.16% - 96.24%Cor e Forma:SolidPeso molecular:325.4Carmustine
CAS:<p>Carmustine (bis-chloroethylnitrosourea) is a cell-cycle phase nonspecific alkylating antineoplastic agent.</p>Fórmula:C5H9Cl2N3O2Pureza:98% - 99.91%Cor e Forma:Light Yellow Powder Physical Description Orange-Yellow Solid (Ntp 1992)Peso molecular:214.05AGK7
CAS:<p>AGK7 is an AGK2 control; it's a less selective SIRT2 inhibitor, with IC50s >5 μM for SIRT3, and >50 μM for SIRT1/2.</p>Fórmula:C23H13Cl2N3O2Pureza:98.31%Cor e Forma:SolidPeso molecular:434.27AZD-7648
CAS:<p>AZD-7648 is an inhibitor of DNA-dependent protein kinase (DNA-PK) with the IC50 of 0.63 nM in an enzyme assay,has anti-tumor activity.</p>Fórmula:C18H20N8O2Pureza:99.03% - 99.85%Cor e Forma:SolidPeso molecular:380.4Xanthosine 5'-monophosphate sodium salt
CAS:<p>Xanthosine 5'-monophosphate sodium salt (L-XMP Sodium) is an intermediate in purine metabolism.</p>Fórmula:C10H11N4Na2O9PPureza:99% - 99.77%Cor e Forma:SolidPeso molecular:408.17Pirarubicin
CAS:<p>Pirarubicin (Theprubicin), an anthracycline antibiotic, inhibits DNA/RNA synthesis and is used as an antineoplastic.</p>Fórmula:C32H37NO12Pureza:97.80% - 99.15%Cor e Forma:Red Crystalline PowderPeso molecular:627.64Levofloxacin hydrochloride
CAS:<p>Levofloxacin is a broad-spectrum, third-generation fluoroquinolone antibiotic and optically active L-isomer of ofloxacin with antibacterial activity.</p>Fórmula:C18H21ClFN3O4Pureza:99.78% - 99.98%Cor e Forma:SolidPeso molecular:397.89-Hydroxycamptothecin
CAS:<p>9-Hydroxycampothecin is a camptothecin derivative with anticancer activity.</p>Fórmula:C20H16N2O5Pureza:98.28%Cor e Forma:SolidPeso molecular:364.35Ganciclovir sodium
CAS:<p>Ganciclovir sodium, a sodium salt with anti-CMV and HSV-1 antiviral properties.</p>Fórmula:C9H13N5NaO4Pureza:99.93%Cor e Forma:SolidPeso molecular:278.22Silver sulfadiazine
CAS:<p>Silver sulfadiazine (Dermazin) is a sulfonamide-based topical agent with antibacterial and antifungal activity.</p>Fórmula:C10H9AgN4O2SPureza:99.04% - 99.58%Cor e Forma:SolidPeso molecular:357.14Deoxycytidine triphosphate
CAS:<p>dCTP is a nucleotide used in DNA synthesis, PCR, cDNA creation, and sequencing.</p>Fórmula:C9H16N3O13P3Pureza:99.68%Cor e Forma:SolidPeso molecular:467.16AZ6102
CAS:<p>AZ6102: Potent TNKS1/2 inhibitor, 100x selective over PARPs, IC50 = 5 nM in DLD-1 Wnt pathway.</p>Fórmula:C25H28N6OPureza:97.98% - 99.91%Cor e Forma:SolidPeso molecular:428.53MK-4827 Racemate
CAS:<p>MK-4827 Racemate (Niraparib Racemate) is a selective PARP1 and PARP2 inhibitor with IC50s of 3.8 nM and 2.1 nM, respectively, over 330-fold selectivity for</p>Fórmula:C19H20N4OPureza:99.86%Cor e Forma:SolidPeso molecular:320.39LMK-235
CAS:<p>LMK-235 is a potent HDAC inhibitor, and is used in cancer research.</p>Fórmula:C15H22N2O4Pureza:98.18% - 99.68%Cor e Forma:SolidPeso molecular:294.35Altretamine hydrochloride
CAS:<p>Altretamine hydrochloride is an alkylating antineoplastic agent.</p>Fórmula:C9H19ClN6Cor e Forma:SolidPeso molecular:246.74Ensulizole
CAS:<p>Ensulizole, a water-soluble UV absorber, damages DNA by generating ROS under UV light, and absorbs UVB and some UVA.</p>Fórmula:C13H10N2O3SPureza:99.79%Cor e Forma:White To Pale Beige Solid PowderPeso molecular:274.30EIDD-1931
CAS:<p>EIDD-1931 (Beta-d-N4-hydroxycytidine) is a ribonucleoside analog with antiviral activity. It inhibits replication of SARS-CoV, MERS-CoV, and SARS-CoV-2.</p>Fórmula:C9H13N3O6Pureza:99.14% - 99.73%Cor e Forma:SolidPeso molecular:259.22CXD101
CAS:<p>CXD101 is a novel class I-selective HDACi (HDAC1 (IC50 : 63nM), HDAC2 (IC50 :570nM), HDAC3 (IC50 :550nM)). CXD101(CXD-101) has no activity against HDAC class II</p>Fórmula:C24H29N5OPureza:99.82%Cor e Forma:SolidPeso molecular:403.522',3',5'-triacetyl-5-Azacytidine
CAS:<p>2',3',5'-triacetyl-5-Azacytidine (Nsc291930) is a prodrug form of 5-azacytidine that may be rapidly absorbed orally.</p>Fórmula:C14H18N4O8Pureza:98.34%Cor e Forma:SolidPeso molecular:370.31AG14361
CAS:<p>AG14361 is an effective inhibitor of PARP1 (Ki<5 nM).</p>Fórmula:C19H20N4OPureza:98.7% - 99.93%Cor e Forma:SolidPeso molecular:320.391-Oleoyl lysophosphatidic acid sodium
CAS:<p>1-Oleoyl lysophosphatidic acid sodium (1-Oleoyl lysophosphatidic acid sodium salt) salt is an Endogenous agonist of LPA1 and LPA2</p>Fórmula:C21H40O7P·NaPureza:98.75% - 99.24%Cor e Forma:SolidPeso molecular:458.51GW9662
CAS:<p>GW9662 (TIMTEC-BB SBB006523) is a PPARγ antagonist (IC50=3.3 nM) with selectivity. GW9662 has anti-tumor effect. High-Quality, Low-Cost!</p>Fórmula:C13H9ClN2O3Pureza:98% - 99.95%Cor e Forma:Off-White SolidPeso molecular:276.681,4-Naphthoquinone
CAS:<p>1,4-Naphthoquinone used as inhibitor for monoamine oxidase, DNA topoisomerase, and acetyltransferase.</p>Fórmula:C10H6O2Pureza:99.24% - 99.56%Cor e Forma:SolidPeso molecular:158.15M344
CAS:<p>M344 (Histone Deacetylase Inhibitor III) is a potent HDAC inhibitor with IC50 of 100 nM and able to induce cell differentiation.</p>Fórmula:C16H25N3O3Pureza:98.18%Cor e Forma:SolidPeso molecular:307.39SRT 1720
CAS:<p>SRT 1720 is a selective activator of human SIRT1 (EC1.5: 0.16 μM) and is >230-fold less potent for SIRT2 and SIRT3.</p>Fórmula:C25H23N7OSPureza:98.84%Cor e Forma:SolidPeso molecular:469.56CM-579 trihydrochloride
<p>CM-579 trihydrochloride: reversible G9a/DNMT inhibitor with IC50s 16 nM (G9a) & 32 nM (DNMT); potent against various cancer cells.</p>Fórmula:C29H43Cl3N4O3Cor e Forma:SolidPeso molecular:602.04NU 7026
CAS:<p>NU 7026 (DNA-PK Inhibitor II) is an effective DNA-PK inhibitor (IC50: 0.23 μM, in cell-free assays), 60-fold selective for DNA-PK than PI3K and no inhibition</p>Fórmula:C17H15NO3Pureza:99.51% - >99.99%Cor e Forma:SolidPeso molecular:281.31NU1025
CAS:<p>NU1025 (NSC-696807) is a potent PARP inhibitor with IC50 of 400 nM.</p>Fórmula:C9H8N2O2Pureza:99.86%Cor e Forma:SolidPeso molecular:176.17Gatifloxacin hydrochloride
CAS:<p>Gatifloxacin hydrochloride, a fourth-gen fluoroquinolone antibiotic, blocks bacterial DNA rotase and topoisomerase IV.</p>Fórmula:C19H23ClFN3O4Pureza:99.85% - 99.89%Cor e Forma:SolidPeso molecular:411.86SirReal2
CAS:<p>SirReal2 is a potent and selective Sirt2 inhibitor with IC50 of 140 nM.</p>Fórmula:C22H20N4OS2Pureza:98.96% - 99.75%Cor e Forma:SolidPeso molecular:420.551-Hydroxyanthraquinone
CAS:<p>1-Hydroxyanthraquinone is an anthraquinone that has been found in Morinda officinalis and has genotoxic and carcinogenic activities.</p>Fórmula:C14H8O3Pureza:99.56%Cor e Forma:Orange Red Needles Red-Orange To Fine Yellow CrystalsPeso molecular:224.21ML216
CAS:<p>ML216 (CID-49852229) inhibits BLM helicase (IC50: 1.8 μM), 28-fold selective over RECQ1, RECQ5, and UvrD (IC50s > 50 μM).</p>Fórmula:C15H9F4N5OSPureza:98.12%Cor e Forma:SolidPeso molecular:383.32NMS-P118
CAS:<p>NMS-P118 is a potent, selective and orally available Inhibitor of PARP-1 for cancer therapy.</p>Fórmula:C20H24F3N3O2Pureza:98.79%Cor e Forma:SolidPeso molecular:395.42Zebularine
CAS:<p>Zebularine (4-Deoxyuridine) is a DNA methylation inhibitor.</p>Fórmula:C9H12N2O5Pureza:99.04% - >99.99%Cor e Forma:SolidPeso molecular:228.2Thymidine
CAS:<p>Thymidine (DThyd) is a cell synchronizing agent and a precursor of deoxyribonucleic acid. Thymidine inhibits DNA synthesis. Cost-effective and quality-assured.</p>Fórmula:C10H14N2O5Pureza:99.64% - 99.86%Cor e Forma:White To Off-White Solid CrystallinePeso molecular:242.23Palifosfamide tromethamine
CAS:<p>Palifosfamide, a less toxic ifosfamide metabolite, is a DNA-alkylating anticancer agent.</p>Fórmula:C8H22Cl2N3O5PCor e Forma:SolidPeso molecular:342.16Azemiglitazone
CAS:<p>Azemiglitazone (MSDC 0602) is an insulin sensitizer potentially for the treatment of diabetes.</p>Fórmula:C19H17NO5SPureza:98.29% - 99.6%Cor e Forma:SolidPeso molecular:371.41UBCS039
CAS:<p>UBCS039 is the first synthetic Sirt6 activator(EC50 : 38 μM)</p>Fórmula:C16H13N3Pureza:98.31%Cor e Forma:SolidPeso molecular:247.29SW-100
CAS:<p>SW-100 is a potent HDAC6 inhibitor with 2.3 nM IC50, highly selective (>1000-fold), can cross blood-brain-barrier.</p>Fórmula:C17H17ClN2O2Pureza:98.34% - 98.47%Cor e Forma:SolidPeso molecular:316.78GSK3685032
CAS:<p>GSK3685032 is a non-covalent and selective DNMT1 inhibitor(IC50 = 36 nM).</p>Fórmula:C22H24N6OSPureza:98.56% - 99.49%Cor e Forma:SolidPeso molecular:420.53L-778123 hydrochloride
CAS:<p>The L-778123 hydrochloride is an inhibitor of FPTase (IC50: 2 nM) and GGPTase-I (IC50: 98 nM) in enzyme inhibition determination.</p>Fórmula:C22H21Cl2N5OPureza:93.93% - 98.51%Cor e Forma:SolidPeso molecular:442.34Indotecan
CAS:<p>Indotecan (LMP-400) is an effective inhibitor of topoisomerase 1(Top1) (IC50: 300, 1200, 560 nM for P388, HCT116, MCF-7 cell lines, respectively).</p>Fórmula:C26H26N2O7Pureza:97% - 98%Cor e Forma:SolidPeso molecular:478.49Hinokitiol
CAS:<p>Hinokitiol prevents UVB-caused cell death, boosts antioxidant activity, and hinders breast cancer growth.</p>Fórmula:C10H12O2Pureza:99.49% - 99.67%Cor e Forma:SolidPeso molecular:164.2PI-3065
CAS:<p>PI-3065 is a novel potent and selective PI3K p110δ inhibitor.</p>Fórmula:C27H31FN6OSPureza:99.84% - ≥95%Cor e Forma:SolidPeso molecular:506.64Senaparib
CAS:<p>Senaparib (IMP4297) is a novel highly potent and selective oral PARP1/2 inhibitor with strong antitumor activity.</p>Fórmula:C24H20F2N6O3Pureza:99.8%Cor e Forma:SolidPeso molecular:478.45Rubitecan
CAS:<p>Rubitecan: a semisynthetic DNA topoisomerase I inhibitor with antitumor and antiviral effects.</p>Fórmula:C20H15N3O6Pureza:97.54%Cor e Forma:Yellow Amorphous PowderPeso molecular:393.35Prulifloxacin
CAS:<p>Prulifloxacin (NM441) is a broad-spectrum fluoroquinolone that inhibits bacterial DNA synthesis by blocking topoisomerase II and IV.</p>Fórmula:C21H20FN3O6SPureza:99.47%Cor e Forma:Yellow Or Slightly Yellow PowerPeso molecular:461.46Ceralasertib
CAS:<p>Ceralasertib (AZD6738) is an ATR kinase inhibitor (IC50=1 nM) with selective and oral activity. Ceralasertib has antitumor activity. Cost effective and quality assured.</p>Fórmula:C20H24N6O2SPureza:98% - 99.99%Cor e Forma:SolidPeso molecular:412.51VE-821
CAS:<p>VE-821 (ATR Inhibitor IV) is a selective ATP competitive inhibitor of ATR( Ki/IC50: 13/26 nM in cell-free assays).</p>Fórmula:C18H16N4O3SPureza:97.19% - 99.97%Cor e Forma:SolidPeso molecular:368.41Cycloastragenol
CAS:<p>Cycloastragenol, a saponin from Astragalus, could be a new depression treatment.</p>Fórmula:C30H50O5Pureza:99.85% - 99.92%Cor e Forma:SolidPeso molecular:490.71γ-Oryzanol
CAS:<p>γ-Oryzanol (Gamma-Oryzanol) is a natural nutrient extract isolated from rice bran oil that contains a mixture of sterols and ferulic acids, which may aid in the</p>Fórmula:C40H58O4Pureza:mixture - mixtureCor e Forma:White Or White Crystalline Powder OdourlessPeso molecular:602.9Thiomyristoyl
CAS:<p>Thiomyristoyl is an effective and selective SIRT2 inhibitor (IC50: 28 nM). It inhibits SIRT1 (IC50: 98 μM) but no effect on SIRT3 even at 200 μM.</p>Fórmula:C34H51N3O3SPureza:99.16%Cor e Forma:SolidPeso molecular:581.85MN-64
CAS:<p>MN-64 is a tankyrases inhibitor, showed 6 nM potency against tankyrase 1, isoenzyme selectivity, and Wnt signaling inhibition.</p>Fórmula:C18H16O2Pureza:99.5% - 99.93%Cor e Forma:SolidPeso molecular:264.32Pixantrone
CAS:<p>Pixantrone has anti-tumor activity that is a DNA intercalator and topoisomerase II inhibitor.</p>Fórmula:C17H19N5O2Cor e Forma:SolidPeso molecular:325.37BMH-21
CAS:<p>BMH-21, a small molecule DNA intercalator, binds ribosomal DNA and inhibits RNA polymerase I (Pol I) transcription and not affects phosphorylation of H2AX.</p>Fórmula:C21H20N4O2Pureza:99.47% - 99.84%Cor e Forma:SolidPeso molecular:360.41
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