NOS
A óxido nítrico sintase (NOS) é uma enzima responsável pela produção de óxido nítrico (NO), uma molécula sinalizadora envolvida na vasodilatação, neurotransmissão e respostas imunológicas. Existem três isoformas de NOS: neuronal (nNOS), endotelial (eNOS) e induzível (iNOS), cada uma desempenhando papéis distintos em processos fisiológicos e patológicos. A desregulação da atividade da NOS está implicada em doenças cardiovasculares, neurodegenerativas e condições inflamatórias. Na CymitQuimica, oferecemos uma seleção de moduladores da NOS para apoiar sua pesquisa em biologia vascular, neurobiologia e imunologia.
Foram encontrados 63 produtos de "NOS"
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Chondroitin sulfate
CAS:<p>Chondroitin sulfate (Chonsurid) is extracted from shark bone;Store the product in sealed, cool and dry condition</p>Fórmula:(C14H21NO14S)nPureza:99.87%Cor e Forma:SolidPeso molecular:30,000-50,0002-Thiouracil
CAS:<p>2-Thiouracil (Deracil) is a thiolated uracil derivative that is a known anti-hyperthyroid agent.</p>Fórmula:C4H4N2OSPureza:99.89%Cor e Forma:Minute Crystals Prisms Or White Or Pale Cream-Colored Powder White To Pale Yellow Crystalline PowderPeso molecular:128.15Carboxyebselen
CAS:<p>Carboxyebselen (HOOC-Ebs) is an endothelial nitric oxide synthase (eNOS) inhibitor that is potent and selective.</p>Fórmula:C14H9NO3SePureza:98%Cor e Forma:SolidPeso molecular:318.19Mifepristone
CAS:<p>Mifepristone (C-1073) is a progesterone-receptor (IC50=0.2 nM) and glucocorticoid-receptor antagonist (IC50=2.6 nM). High-Quality, Low-Cost!</p>Fórmula:C29H35NO2Pureza:98.9% - ≥95%Cor e Forma:Pale Yellow SolidPeso molecular:429.59Aminoguanidine hydrochloride
CAS:<p>Aminoguanidine hydrochloride (Hydrazinecarboximidamide) is a diamine oxidase and NO synthase inhibitor, used in the treatment of diabetic nephropathy.</p>Fórmula:CH6N4·HClPureza:99.80%Cor e Forma:White To Off-White SolidPeso molecular:110.55L-Arginine hydrochloride
CAS:<p>L-Arginine hydrochloride is a nitrogen donor for synthesis of nitric oxide.</p>Fórmula:C6H15ClN4O2Pureza:99.51%Cor e Forma:White Solid CrystallinePeso molecular:210.66S-Nitroso-N-acetyl-DL-penicillamine
CAS:<p>S-Nitroso-N-acetyl-DL-penicillamine (SNAP) acts as a stable inhibitor of platelet aggregation, is a nitric oxide donor and .</p>Fórmula:C7H12N2O4SPureza:97.42% - >99.99%Cor e Forma:Green Crystalline SolidPeso molecular:220.25Bendazol
CAS:<p>Bendazol (Dibazol) is always used as the drug for hypertension and cerebral Angiospasm.</p>Fórmula:C14H12N2Pureza:98.7% - 99.87%Cor e Forma:White Or Almost White Crystalline PowderPeso molecular:208.26Isosorbide dinitrate
CAS:<p>Isosorbide dinitrate (Isordil) is a vasodilator used in the treatment of angina pectoris.</p>Fórmula:C6H8N2O8Pureza:99.87%Cor e Forma:Hard Colorless Crystals SolidPeso molecular:236.14NOS-IN-1
CAS:<p>NOS-IN-1: a potent oral NO synthase blocker, with IC50 of 0.1μM (iNOS), 0.2μM (nNOS), 1.1μM (eNOS).</p>Fórmula:C8H16N2O2Pureza:99.8%Cor e Forma:SolidPeso molecular:172.22Epibetulinic acid
CAS:<p>Epibetulinic acid reduces inflammation, suppressing NO and prostaglandin E2 in endotoxin-stimulated mouse macrophages.</p>Fórmula:C30H48O3Pureza:99.66%Cor e Forma:SolidPeso molecular:456.73-O-Acetyl-16α-hydroxydehydrotrametenolic acid
CAS:<p>3-O-Acetyl-16α-hydroxydehydrotrametenolic acid (3-O-Acetyl-16 alpha-hydroxydehydrotrametenolic acid) shows anti-inflammatory activity, it can inhibit NO</p>Fórmula:C32H48O5Pureza:98%Cor e Forma:SolidPeso molecular:512.722-Iminobiotin
CAS:<p>2-Iminobiotin inhibits iNOS/nNOS; Ki: 21.8 μM (mouse iNOS), 37.5 μM (rat nNOS).</p>Fórmula:C10H17N3O2SPureza:98%Cor e Forma:SolidPeso molecular:243.33Physalin L
CAS:<p>Physalin L is a natural product,it shows a distinct fluorescence spot under UV 365 nm with good separation.</p>Fórmula:C28H32O10Pureza:98%Cor e Forma:SolidPeso molecular:528.55Banoxantrone dihydrochloride
CAS:<p>Banoxantrone dihydrochloride (AQ4N dihydrochloride) is a novel hypoxic cytotoxin that selectively kills hypoxic cells through an iNOS-dependent mechanism.</p>Fórmula:C22H30Cl2N4O6Pureza:99.88%Cor e Forma:SolidPeso molecular:517.4Asperuloside
CAS:<p>Asperuloside (Asperulosid) has anti-inflammatory activity.</p>Fórmula:C18H22O11Pureza:98.03% - 99.42%Cor e Forma:SolidPeso molecular:414.36Asymmetric dimethylarginine
CAS:<p>Asymmetric dimethylarginine is an endogenous inhibitor of nitric oxide synthase (NOS)</p>Fórmula:C8H18N4O2Pureza:98% - 99.62%Cor e Forma:SolidPeso molecular:202.257-Nitroindazole
CAS:<p>7-Nitroindazole is a non-selective inhibitor of NOS isoforms in vitro for neuronal nitric oxide synthase showing a 10-fold selectivity for neuronal NOS.</p>Fórmula:C7H5N3O2Pureza:96.15% - 99.05%Cor e Forma:Orange-Yellow SolidPeso molecular:163.13Tryptanthrin
CAS:<p>Tryptanthrin is a natural DNA gyrase inhibitor.</p>Fórmula:C15H8N2O2Pureza:99.64% - 99.94%Cor e Forma:SolidPeso molecular:248.24Ethyl 3,4-dihydroxybenzoate
CAS:<p>Ethyl 3,4-dihydroxybenzoate (EDHB): a prolyl hydroxylase inhibitor attenuates acute hypobaric hypoxia mediated vascular leakage in brain.</p>Fórmula:C9H10O4Pureza:99.88%Cor e Forma:White Crystal Or PowderPeso molecular:182.17α-Humulene
CAS:<p>α-Humulene (Alpha-caryophyllene) is extracted from S.officinalis essential oil.α-Humulene can inhibit tumor cell growth.α-Humulene also shows anti-inflammatory</p>Fórmula:C15H24Pureza:97.18% - 97.18%Cor e Forma:LiquidPeso molecular:204.35Diphenyleneiodonium chloride
CAS:<p>Diphenyleneiodonium chloride (DPI) inhibits iNOS & eNOS (IC50: 50 nM & 0.3 μM) and has wide-ranging bactericidal properties.</p>Fórmula:C12H8ClIPureza:99.71% - 99.86%Cor e Forma:SolidPeso molecular:314.55Piceatannol 3'-O-glucoside
CAS:<p>Piceatannol 3'-O-glucoside (Piceatannol 3-glycoside) increases pulmonary blood oxygen tension and decreases pulmonary interstitial edema, so it can protect lung</p>Fórmula:C20H22O9Pureza:99.47% - 99.97%Cor e Forma:SolidPeso molecular:406.38S-Methylisothiourea sulfate
CAS:<p>S-Methylisothiourea sulfate ((S)-Methylisothiourea sulfate) is a potent and selective inhibitor of iNOS and exerts beneficial effects in rodent models of septic</p>Fórmula:C2H6N2SH2O4SPureza:99.58%Cor e Forma:SolidPeso molecular:139.18Midostaurin
CAS:<p>PKC412(Midostaurin (PKC412); CGP41231; CGP41251) is a broad spectrum protein kinase inhibitor.</p>Fórmula:C35H30N4O4Pureza:97.61% - >99.99%Cor e Forma:SolidPeso molecular:570.64Avanafil
CAS:<p>Avanafil (TA1790) is a selective inhibitor of phosphodiesterase type 5 (PDE5) and is used as therapy of erectile dysfunction.</p>Fórmula:C23H26ClN7O3Pureza:99.03% - >99.99%Cor e Forma:White SolidPeso molecular:483.95Ginsenoside Rb3
CAS:<p>Ginsenoside Rb3 (Gypenoside IV) is a natural triterpenoid saponin, exhibiting inhibition effect on TNFα-induced NF-κB transcriptional activity.</p>Fórmula:C53H90O22Pureza:98% - 99.98%Cor e Forma:SolidPeso molecular:1079.27L-Canavanine sulfate
CAS:<p>L-Canavanine sulfate is a selective inducible NO synthase inhibitor.</p>Fórmula:C5H14N4O7SPureza:99.73%Cor e Forma:SolidPeso molecular:274.256-Biopterin
CAS:<p>6-Biopterin (L-Biopterin) is a natural product,is a NO synthase cofactor.</p>Fórmula:C9H11N5O3Pureza:99.11%Cor e Forma:SolidPeso molecular:237.22Irisflorentin
CAS:<p>Irisflorentin prevents cell death, boosts proteasomes via rpn-3, reduces egl-1, and lowers iNOS/NO in LPS-stimulated macrophages.</p>Fórmula:C20H18O8Pureza:98.6% - 99.81%Cor e Forma:SolidPeso molecular:386.35Methylene Blue
CAS:<p>Methylene Blue (Tetramethylthionine chloride) (IC50 of 1.9 μM) inhibits tau filament formation. And methylene Blue inhibits soluble guanylyl cyclase.</p>Fórmula:C16H18ClN3SPureza:95.80%Cor e Forma:Dark Green Crystals Or Powder From Chloroform-Ethyl Ether Green Fine Crystalline PowderPeso molecular:319.85Pectolinarin
CAS:<p>Pectolinarin is a Cirsium isolate with anti-inflammatory activity.</p>Fórmula:C29H34O15Pureza:98% - 99.79%Cor e Forma:SolidPeso molecular:622.57PRE-084 hydrochloride
CAS:<p>PRE-084 hydrochloride is a selective agonist of σ1(IC50:44 nM, in the sigma receptor assay).</p>Fórmula:C19H28ClNO3Pureza:99.54%Cor e Forma:SolidPeso molecular:353.88Agmatine sulfate
CAS:<p>Agmatine sulfate (Agmatine sulfate salt) is a bioactive metabolite of the arginine amino acid.</p>Fórmula:C5H16N4O4SPureza:99.56% - 99.86%Cor e Forma:White To Off-White PowderPeso molecular:228.27Regaloside B
CAS:<p>Regaloside B, a phenylpropanoid isolated from Lilium longiflorum, exhibits anti-inflammatory activity by inhibiting the expression of iNOS (inducible nitric</p>Fórmula:C20H26O11Pureza:99.4% - 99.57%Cor e Forma:SolidPeso molecular:442.41anemarsaponin B
CAS:<p>Anemarsaponin B has anti-inflammatory effect in LPS-treated RAW 264.7macrophages, the effect is associated with the inhibition of NF-κB transcriptional activity</p>Fórmula:C45H74O18Pureza:99.06% - 99.81%Cor e Forma:SolidPeso molecular:903.06Dehydroevodiamine
CAS:<p>Dehydroevodiamine (DHED), a constituent of Evodia rutaecarpa, has various biological effects such as hypotensive, negative chronotropic, ion channel depressant</p>Fórmula:C19H15N3OPureza:99.54%Cor e Forma:SolidPeso molecular:301.347-Ethoxyresorufin
CAS:<p>7-Ethoxyresorufin (Resorufin ethyl ether) (7-ER) is a fluorometric substrate for and competitive inhibitor of cytochrome P450, especially CYP1A1.</p>Fórmula:C14H11NO3Pureza:99.09% - 99.62%Cor e Forma:Red SolidPeso molecular:241.24L-Arginine
CAS:<p>L-Arginine (L-Arg) is a substrate of endothelial nitric oxide synthase (eNOS). High-Quality, Low-Cost!</p>Fórmula:C6H14N4O2Pureza:99.7% - 99.98%Cor e Forma:Solid CrystallinePeso molecular:174.2Prim-O-glucosylcimifugin
CAS:<p>Prim-O-glucosylcimifugin (Cimifugin 7-glucoside) can inhibit the proliferation of SMC stimulated by TNF-alpha, increase the proportion of G0/G1 phase.</p>Fórmula:C22H28O11Pureza:98.57% - 99.92%Cor e Forma:SolidPeso molecular:468.45Methylene Blue trihydrate
CAS:<p>Dark green, bronze-lustered Methylene Blue trihydrate is a deep blue dye in water/alcohol, used in staining, cyanide treatment, and methemoglobin reduction.</p>Fórmula:C16H24ClN3O3SPureza:95.42% - 99.6%Cor e Forma:Dark Green SolidPeso molecular:373.91400W dihydrochloride
CAS:<p>1400W dihydrochloride (N-(3-(Aminomethyl)benzyl)acetamidine) is a highly effective and specific inhibitor of inducible NOS2 (iNOS).</p>Fórmula:C10H17Cl2N3Pureza:98% - 99.94%Cor e Forma:SolidPeso molecular:250.17N'-Nitro-D-arginine
CAS:<p>N'-Nitro-D-arginine (N'-Nitro-D-arginine) is a Building Block.</p>Fórmula:C6H13N5O4Pureza:99.81%Cor e Forma:White To Off White PowderPeso molecular:219.2Dimaprit dihydrochloride
CAS:<p>Dimaprit dihydrochloride: selective H2 agonist, inhibits nNOS (IC50: 49 μM), boosts gastric acid.</p>Fórmula:C6H15N3S·2HClPureza:99.79%Cor e Forma:SolidPeso molecular:234.19ETHYL CAFFEATE
CAS:<p>Ethyl Caffeate (ETHYL 3,4-DIHYDROXYCINNAMATE) suppressed the differentiation of naive CD4+ T cells into Th1 in vitro.</p>Fórmula:C11H12O4Pureza:97.79%Cor e Forma:SolidPeso molecular:208.21Isoquercetin
CAS:<p>1.</p>Fórmula:C21H20O12Pureza:98.08% - 99.76%Cor e Forma:SolidPeso molecular:464.38Harpagoside
CAS:<p>Harpagoside: anti-inflammatory; 3 mM inhibits seed germination; reduces COX-2, iNOS mRNA, and protein in HepG2.</p>Fórmula:C24H30O11Pureza:99.71% - ≥95%Cor e Forma:White To Off-White PowderPeso molecular:494.49TRIM
CAS:<p>TRIM (1-(2-Trifluoromethylphenyl)imidazole) is an inhibitor of nNOS.</p>Fórmula:C10H7F3N2Pureza:98.98%Cor e Forma:White SolidPeso molecular:212.172-Iminobiotin hydrobromide
CAS:<p>2-Iminobiotin hydrobromide (Guanidinobiotin) is a cyclic guanidino analog of biotin that acts as a reversible inhibitor of inducible nitric oxide synthase (iNOS</p>Fórmula:C10H18BrN3O2SPureza:98.13%Cor e Forma:SolidPeso molecular:324.24Ginsenoside C-K
CAS:<p>Ginsenoside C-K (Ginsenoside K) is a bacterial metabolite of G-Rb1 exhibiting anti-inflammatory effects by reducing iNOS and COX-2.</p>Fórmula:C36H62O8Pureza:99.65% - 99.97%Cor e Forma:SolidPeso molecular:622.87
