Neurociência
Os inibidores de neurociência são compostos projetados para modular a atividade de proteínas, enzimas ou receptores específicos no sistema nervoso. Esses inibidores são cruciais para estudar os mecanismos moleculares subjacentes à função neural, transmissão sináptica e doenças neurodegenerativas. Ao direcionar receptores de neurotransmissores, canais iônicos e vias de sinalização, os inibidores de neurociência ajudam na exploração da função cerebral e no desenvolvimento de estratégias terapêuticas para distúrbios neurológicos como Alzheimer, Parkinson e epilepsia. Na CymitQuimica, oferecemos uma ampla gama de inibidores de neurociência de alta qualidade para apoiar sua pesquisa em neurobiologia, neurofarmacologia e ciências cognitivas.
Subcategorias de "Neurociência"
- Receptor 5-HT(940 produtos)
- ACK(1 produtos)
- AChR(574 produtos)
- ATP Citrato Liase(16 produtos)
- Receptor adrenérgico(2.939 produtos)
- BACE(36 produtos)
- Beta Amilóide(204 produtos)
- CaMK(68 produtos)
- COX(562 produtos)
- Receptor de Dopamina(407 produtos)
- Receptor GABA(336 produtos)
- Gama-secretase(59 produtos)
- GluR(255 produtos)
- GlyT(24 produtos)
- Receptor de Histamina(358 produtos)
- LRRK2(33 produtos)
- Receptor de Melatonina(24 produtos)
- NMDAR(28 produtos)
- Receptor OX(40 produtos)
- Receptor opioide(296 produtos)
Exibir 12 mais subcategorias
Foram encontrados 5400 produtos de "Neurociência"
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Pimethixene maleate
CAS:<p>Pimethixene maleate (Pimetixene maleate) is a 5-HT2B receptor antagonist with sedative activity that can be used to study dry cough in children.</p>Fórmula:C23H23NO4SPureza:99.55%Cor e Forma:SolidPeso molecular:409.5BMY-14802 hydrochloride
CAS:<p>BMY-14802 hydrochloride (BMS 181100 hydrochloride) is a selective antagonist of σ receptor (IC50 = 112 nM) with antipsychotic effects.</p>Fórmula:C18H23ClF2N4OPureza:99.97%Cor e Forma:SolidPeso molecular:384.85GR 46611
CAS:<p>GR 46611 is a selective 5-HT1B and 5-HT1D receptor agonist and can be used in studies about the treatment of epilepsy.</p>Fórmula:C23H27N3O2Pureza:99.75%Cor e Forma:SolidPeso molecular:377.482-BFI hydrochloride
CAS:<p>2-BFI hydrochloride: High-affinity I2 agonist; used in researching stroke and immune disease protection.</p>Fórmula:C11H11ClN2OPureza:99.94%Cor e Forma:SolidPeso molecular:222.67SB-215505
CAS:<p>SB215505: potent 5-HT2B/2C blocker, enhances rat wakefulness/motor activity. (pKi: 5-HT2B - 8.3, 5-HT2C - 7.66, 5-HT2A - 6.77).</p>Fórmula:C19H16ClN3OPureza:98.33%Cor e Forma:SolidPeso molecular:337.8Tedatioxetine
CAS:<p>Tedatioxetine (Lu AA24530) is a serotonin-norepinephrine-dopamine reuptake inhibitor (SNDRI) with antidepressant properties.</p>Fórmula:C18H21NSPureza:99.76% - >99.99%Cor e Forma:SolidPeso molecular:283.43Otenzepad
CAS:<p>Otenzepad (AF-DX 116) is a selective antagonist of M2 mAChR with IC50s of 386 nM and 640 nM for rat heart and rabbit peripheral lung.</p>Fórmula:C24H31N5O2Pureza:99.79%Cor e Forma:SolidPeso molecular:421.54Landipirdine
CAS:<p>Landipirdine (RO-5025181) is a selective 5-HT6R antagonist for the study of central nervous system disorders such as dementia.</p>Fórmula:C18H19FN2O3SPureza:97.61% - 99.37%Cor e Forma:SolidPeso molecular:362.42JNJ-54175446
CAS:<p>JNJ-54175446 (JNJ-5446) is a P2X7 receptor antagonist that attenuates the release of IL-1β/IL-18 from microglia and is used in the study of depression.</p>Fórmula:C18H13ClF4N6OPureza:97.98% - 99.79%Cor e Forma:SolidPeso molecular:440.78LY266097 hydrochloride
CAS:<p>LY266097 hydrochloride is a 5-HT2 antagonist with pKi of 7.7/9.8/7.6 for 5-HT2A/B/C, used in depression research.</p>Fórmula:C21H24Cl2N2O2Pureza:98.58%Cor e Forma:SolidPeso molecular:407.33GSK-1482160
CAS:<p>GSK-1482160 is a CNS-penetrant negative allosteric modulator of P2X7 receptor with oral activity.</p>Fórmula:C14H14ClF3N2O2Pureza:99.57%Cor e Forma:SolidPeso molecular:334.72CPCCOEt
CAS:<p>CPCCOEt is a low affinity, selective, non-competitive and reversible antagonist of mGluR1b</p>Fórmula:C13H13NO4Pureza:99.91%Cor e Forma:SolidPeso molecular:247.25UK-240455
CAS:<p>UK-240455: Potent NMDA glycine antagonist with neuroprotection and motor function benefits in Parkinson's.</p>Fórmula:C11H11Cl2N3O5SPureza:98.34% - 99.84%Cor e Forma:SolidPeso molecular:368.198-OH-Dpat
CAS:<p>8-OH-Dpat (8-Hydroxy-DPAT) is a serotonin 1A-receptor agonist that is used experimentally to test the effects of serotonin.</p>Fórmula:C16H25NOPureza:98%Cor e Forma:SolidPeso molecular:247.38Valiglurax
CAS:<p>Valiglurax (VU2957), potent mGlu4 PAM, crosses blood-brain barrier, orally available; promising for Parkinson's treatment.</p>Fórmula:C16H10F3N5Pureza:98.29%Cor e Forma:SolidPeso molecular:329.28LM-1685
CAS:<p>LM-1685是一种有效且具有选择性的人单核细胞和全血中COX-2抑制剂，IC50分别为0.65 µM 和IC50 = 4.3 μM，是治疗炎症的潜在化合物。</p>Fórmula:C18H16ClNO4SPureza:98.16%Cor e Forma:SolidPeso molecular:377.84Apyramide
CAS:<p>Apyramide, an NSAID and prodrug of indomethacin, inhibits COX1/COX2 and permeates the blood-brain barrier.</p>Fórmula:C27H23ClN2O5Pureza:99.93%Cor e Forma:SolidPeso molecular:490.93LY-2624803
CAS:<p>LY-2624803 is a 5-HT2A receptor antagonist and histamine receptor inverse agonist that can be used to improve slow wave sleep.</p>Fórmula:C22H25N3O3Pureza:99.78% - 99.97%Cor e Forma:SolidPeso molecular:379.45MM 77 dihydrochloride
CAS:<p>MM 77 dihydrochloride is an effecitve 5-HT1A receptor postsynaptic antagonist with anxiolytic-like activity.</p>Fórmula:C19H29Cl2N3O3Pureza:99.91%Cor e Forma:SolidPeso molecular:418.365HT6-ligand-1
CAS:<p>5HT6-ligand-1 is an orally active ligand of 5-HT6 receptor (Ki = 1.43 nM).</p>Fórmula:C20H22BrN3O2SPureza:99.24% - 99.93%Cor e Forma:SolidPeso molecular:448.38ALX-1393
CAS:<p>ALX-1393 is a selective GlyT2 inhibitor that effectively reduces neuronal action potential activity in a concentration-dependent manner and inhibits the</p>Fórmula:C23H22FNO4Pureza:99.83%Cor e Forma:SolidPeso molecular:395.42Lesopitron
CAS:<p>Lesopitron: anxiolytic, 5-HT1A agonist, treats rodent anxiety, counters benzodiazepine withdrawal, low toxicity, no alcohol/barbiturate interaction.</p>Fórmula:C15H21ClN6Pureza:99.15% - 99.38%Cor e Forma:SolidPeso molecular:320.82Sudoxicam
CAS:<p>Sudoxicam (4-Hydroxy-2-methyl-N-2-thiazolyl-2H-1,2-benzothiazine-3-carboxamide 1,1-dioxide) is a reversible antagonist of COX with anti-inflammatory, anti-edema</p>Fórmula:C13H11N3O4S2Pureza:99.93%Cor e Forma:SolidPeso molecular:337.37Lenumlostat
CAS:<p>Lenumlostat is a lysyl oxidase-like protein 2 (LOXL2) inhibitor with inhibitory effects on hLOXL2, hLOXL3 and LOXL2 for the study of fibrotic diseases.</p>Fórmula:C18H17F4N3O3Pureza:99.11%Cor e Forma:SolidPeso molecular:399.34Nerisopam
CAS:<p>Nerisopam is an agonist of gamma-aminobutyric acid (GABA) receptor.</p>Fórmula:C18H19N3O2Pureza:97.07%Cor e Forma:SolidPeso molecular:309.36Muscimol HBr
CAS:<p>Muscimol HBr (Agarin HBr) is an agonist of GABAA receptor.</p>Fórmula:C4H7BrN2O2Pureza:98.13%Cor e Forma:Off-White PowderPeso molecular:195.01Fengabine
CAS:<p>Fengabine (SL-79229) is a GABA receptor agonist with antidepressant activity and is used to treat depression.</p>Fórmula:C17H17Cl2NOPureza:99%Cor e Forma:SolidPeso molecular:322.23Itasetron
CAS:<p>Itasetron, a 5-HT3 antagonist, prevents memory loss in rats and has antiemetic effects in cancer treatments.</p>Fórmula:C16H20N4O2Pureza:98.58% - 99.33%Cor e Forma:SolidPeso molecular:300.36Cilansetron
CAS:<p>Cilansetron is an effective and selective 5-HT3 receptor antagonist that can be used for related diseases caused by colitis.</p>Fórmula:C20H21N3OPureza:99.82% - 99.98%Cor e Forma:SolidPeso molecular:319.4BI-1408
CAS:<p>BI-1408 is a modulator potent of γ secretase (IC50: 0.04 μM for Aβ42).</p>Fórmula:C22H23FN6Pureza:99.63%Cor e Forma:SolidPeso molecular:390.46L-838417
CAS:<p>L-838417 is a GABAA receptor subtype-selective benzodiazepine site-selective ligand and GABAA receptor-positive modulator used in the study of anxiety disorders</p>Fórmula:C19H19F2N7OPureza:98.12% - 99.70%Cor e Forma:SolidPeso molecular:399.4Liafensine
CAS:<p>Liafensine(BMS-820836): Selective inhibitor for serotonin, norepinephrine, dopamine reuptake; targets major depression, CNS disorders.</p>Fórmula:C24H22N4Pureza:99.91%Cor e Forma:SolidPeso molecular:366.46Nexopamil
CAS:<p>Nexopamil (LU-49938) is a dual calcium channel and 5-HT2A receptor antagonist that inhibits cell contraction and growth.</p>Fórmula:C24H40N2O3Pureza:97.87% - >99.99%Cor e Forma:SolidPeso molecular:404.59W-9 hydrochloride
CAS:<p>W-9 hydrochloride is a calmodulin antagonist.</p>Fórmula:C16H22Cl2N2O2SPureza:98.9%Cor e Forma:SolidPeso molecular:377.33Lensiprazine
CAS:<p>Lensiprazine (SLV314) is a potent dopamine D(2) receptor antagonist that acts as a serotonin reuptake inhibitor , and can be used to study bipolar disorder and</p>Fórmula:C24H27FN4O2Pureza:98.04%Cor e Forma:SolidPeso molecular:422.5H-9 dihydrochloride
CAS:<p>H-9 dihydrochloride: Strong PKA inhibitor, curbs 5-HT response and EGF signaling, affects pharyngeal function.</p>Fórmula:C11H15Cl2N3O2SPureza:97.3%Cor e Forma:SolidPeso molecular:324.23RWJ-51204
CAS:<p>RWJ-51204: potent adenosine A2A blocker, GABA(A) partial agonist (IC50: 0.2-2 nM), neuroprotective, may treat Parkinson's.</p>Fórmula:C21H19F2N3O3Pureza:99.57% - 99.95%Cor e Forma:SolidPeso molecular:399.39Ricasetron
CAS:<p>Ricasetron (Brl 46470) is a 5-HT3 receptor antagonist with pro-axonal lysing properties and is used in the study of anxiety disorders and anxiety disorders.</p>Fórmula:C19H27N3OPureza:99.52%Cor e Forma:SolidPeso molecular:313.44CGP 37849
CAS:<p>CGP 37849: oral NMDA antagonist (Ki=35 nM), anticonvulsant, with antidepressant/anxiolytic effects.</p>Fórmula:C6H12NO5PPureza:99.87%Cor e Forma:White SolidPeso molecular:209.14Adoprazine
CAS:<p>Adoprazine (SLV313) is a potential atypical antipsychotic bearing potent D2 receptor antagonist and 5-HT1A receptor agonist properties.</p>Fórmula:C24H24FN3O2Pureza:99.83%Cor e Forma:SolidPeso molecular:405.46Tribendimidine
CAS:<p>Tribendimidine: broad-spectrum oral anthelmintic, nAChR agonist, effective against A. lumbricoides and N. americanus.</p>Fórmula:C28H32N6Pureza:≥98%Cor e Forma:SolidPeso molecular:452.59Repinotan
CAS:<p>Repinotan (BAY x 3702 free base) is a 5-HT1A receptor agonist used in acute ischemic stroke studies.</p>Fórmula:C21H24N2O4SPureza:99%Cor e Forma:SolidPeso molecular:400.49McN-A 343
CAS:<p>McN-A 343: Selective M1 muscarinic agonist; reduces inflammation in colitis models.</p>Fórmula:C14H18Cl2N2O2Pureza:99.65%Cor e Forma:SolidPeso molecular:317.21amyloid P-IN-1
CAS:<p>amyloid P-IN-1 can be used in studies about diseases with depletion of serum amyloid P components such as Alzheimer's disease, amyloidosis, osteoarthritis, and</p>Fórmula:C30H44N2O14Pureza:99.76%Cor e Forma:SolidPeso molecular:656.68Xanomeline oxalate
CAS:<p>Xanomeline oxalate (LY246708), a potent SMRA, boosts phosphoinositide hydrolysis; key for Alzheimer's research.</p>Fórmula:C16H25N3O5SPureza:99.1%Cor e Forma:SolidPeso molecular:371.45PNU-282987 free base
CAS:<p>PNU-282987 is an α7 nAChR agonist (EC50=154 nM) and a 5-HT3 antagonist (IC50=4541 nM) for nervous system research.</p>Fórmula:C14H17ClN2OPureza:99.64%Cor e Forma:SolidPeso molecular:264.75PAT-1251
CAS:<p>PAT-1251 is an inhibitor of LOXL2 with IC50s of 10, 0.12, and 0.16 μM for the mouse, rat, and dog and can be used in studies about fibrotic diseases.</p>Fórmula:C18H17F4N3O3Pureza:97.27% - 98.46%Cor e Forma:SolidPeso molecular:399.34AMPA receptor antagonist-2
CAS:<p>AMPA receptor antagonist-2 is an AMPA receptor antagonist.</p>Fórmula:C18H17N3O4Pureza:98.76%Cor e Forma:SolidPeso molecular:339.35SB228357
CAS:<p>SB228357 is a potent and selective antagonist of the 5-HT receptor with pKis of 6.9, 8.0, and 9.0 for 5-HT2A, 5-HT2B, and 5-HT2C, respectively.</p>Fórmula:C22H17F4N3O2Pureza:99.82%Cor e Forma:SolidPeso molecular:431.38MNI 137
CAS:<p>MNI 137 is a negative allosteric modulator of mGlu2. MNI 137 inhibits glutamate-induced calcium mobilization with IC50s of 8.3 and 12.6 nM for human and rat.</p>Fórmula:C15H9BrN4OPureza:97.49%Cor e Forma:SolidPeso molecular:341.16GSK233705
CAS:<p>GSK233705, a muscarinic antagonist, is used to prevent/treat COPD and asthma.</p>Fórmula:C24H29BrN2Pureza:99.87% - 99.98%Cor e Forma:SolidPeso molecular:425.4Progabide
CAS:<p>Progabide (SL 76002) is an agonist of the gamma-aminobutyric acid receptor.</p>Fórmula:C17H16ClFN2O2Pureza:99.68%Cor e Forma:SolidPeso molecular:334.77Mibampator
CAS:<p>Mibampator (LY451395) is an effective and selective AMPA receptor potentiator.</p>Fórmula:C21H30N2O4S2Pureza:99.34%Cor e Forma:SolidPeso molecular:438.6BPDBA
CAS:<p>BPDBA is an effective, selective, and non-competitive inhibitor of the betaine/GABA transporter (BGT-1), displaying inhibitory activity against human BGT-1 and</p>Fórmula:C19H20Cl2N2OPureza:99.37% - 99.95%Cor e Forma:SolidPeso molecular:363.28Divaplon
CAS:<p>Divaplon is a GABA receptor agonist (IC50: 0.056 µM) that displays non-sedating anxiolytic behavioral characteristics in a rat model of anxiety.</p>Fórmula:C17H17N3O2Pureza:97.44% - 98.25%Cor e Forma:SolidPeso molecular:295.34LRRK2-IN-7
CAS:<p>LRRK2-IN-7: potent, selective CNS-active LRRK2 inhibitor, IC50 0.9 nM, >1000x selectivity vs kinases/channels/CYPs.</p>Fórmula:C24H26N6OPureza:99.26%Cor e Forma:SolidPeso molecular:414.5Cyamemazine
CAS:<p>Cyamemazine is an antipsychotic compound with sedative and anxiolytic activity.Cyamemazine is a 5-HT3, 5-HT2A, and 5-HT2C receptor antagonist.</p>Fórmula:C19H21N3SPureza:97.01%Cor e Forma:SolidPeso molecular:323.46LY 272015 hydrochloride
CAS:<p>LY 272015 hydrochloride is a 5-HT2B receptor antagonist.</p>Fórmula:C21H25ClN2O2Pureza:99.47%Cor e Forma:SolidPeso molecular:372.89NS-2710
CAS:<p>NS-2710, a GABA receptor agonist, is used potentially for the treatment of anxiety.</p>Fórmula:C22H20N4OPureza:99.7% - 99.82%Cor e Forma:SolidPeso molecular:356.42Femoxetine hydrochloride
CAS:<p>Femoxetine hydrochloride is a selective 5-hydroxytryptamine reuptake inhibitor used in the study of migraine, depression and eating disorders.</p>Fórmula:C20H26ClNO2Pureza:99.63%Cor e Forma:SolidPeso molecular:347.88Fenlean
CAS:<p>"Fenlean (FLZ) in phase I trial at Chinese Academy's Institute of Pharmacy for Parkinson's treatment."</p>Fórmula:C26H27NO6Pureza:98.99%Cor e Forma:SolidPeso molecular:449.5ADX71441
CAS:<p>ADX71441, a GABAB PAM, lengthens urinary latencies, lessens events & volume, and may aid in alcoholism and bladder pain.</p>Fórmula:C19H15ClF2N4O4Cor e Forma:SolidPeso molecular:436.8A-424274
CAS:<p>A-424274 is a positive allosteric modulator of α4β2 neuronal nicotinic receptor.</p>Fórmula:C14H15N3Pureza:98%Cor e Forma:SolidPeso molecular:225.29GR 125487 sulfamate
CAS:<p>GR 125487 sulfamate is a 5-HT4 receptor antagonist.</p>Fórmula:C19H29FN4O8S2Pureza:98%Cor e Forma:SolidPeso molecular:524.58LY320954
CAS:<p>LY320954 is an antagonist of 5-HT2A receptor.</p>Fórmula:C21H26N4O3Pureza:98%Cor e Forma:SolidPeso molecular:382.46AZ10606120 dihydrochloride
CAS:<p>AZ10606120 dihydrochloride is a selectable, potent, high-affinity receptor antagonist with K D values of 1.4 and 19 nM at human and rat P2X 7 receptors,</p>Fórmula:C25H36Cl2N4O2Pureza:99.49%Cor e Forma:SolidPeso molecular:495.486,2'-Dihydroxyflavone
CAS:<p>6,2'-Dihydroxyflavone is a novel antagonist of GABAA receptor.</p>Fórmula:C15H10O4Pureza:99.44% - 99.67%Cor e Forma:SolidPeso molecular:254.24BACE1-IN-10
CAS:<p>BACE1-IN-10 is a potent inhibitor of BACE1, demonstrating sub-micromolar activity against recombinant BACE1 (rBACE1) [1].</p>Fórmula:C33H49N5O8SPureza:98%Cor e Forma:SolidPeso molecular:675.84SB 258719
CAS:<p>SB 258719 is a selective antagonist of 5-HT7 receptor with pKi of 7.5.</p>Fórmula:C18H30N2O2SPureza:99.73%Cor e Forma:SolidPeso molecular:338.51Adenylyl cyclase-IN-1
CAS:<p>Adenylyl cyclase-IN-1 is a potential adenylyl cyclase inhibitor for ocular hypotonia research [1].</p>Fórmula:C9H8N2S3Cor e Forma:SolidPeso molecular:240.37MK-8768
CAS:<p>MK-8768 is a potent, selective, and orally bioavailable negative allosteric modulator of the mGluR2 class, exhibiting an IC50 of 9.6 nM and characterized by</p>Fórmula:C21H22F3N5O2Cor e Forma:SolidPeso molecular:433.43Osemozotan Free Base
CAS:<p>Osemozotan Free Base is a 5-HT(1A) receptor agonist.</p>Fórmula:C19H21NO5Cor e Forma:SolidPeso molecular:343.37PTAC oxalate
CAS:<p>muscarinic receptor ligand</p>Fórmula:C14H21N3O4S2Pureza:98%Cor e Forma:SolidPeso molecular:359.46JM-1232
CAS:<p>JM-1232 is a sedative and hypnotic drug being researched as a potential anesthetic.</p>Fórmula:C24H27N3O2Cor e Forma:SolidPeso molecular:389.49PZ-1190
CAS:<p>PZ-1190, a multitarget ligand for serotonin and dopamine receptors, exhibits potential antipsychotic activity in rodents [1].</p>Fórmula:C27H30N4O2S2Pureza:98%Cor e Forma:SolidPeso molecular:506.68VU0029251
CAS:<p>VU0029251 serves as a partial antagonist of mGluR5, exhibiting a binding affinity with a K i of 1.07 μM.</p>Fórmula:C10H11N3S2Cor e Forma:SolidPeso molecular:237.34Diproqualone
CAS:<p>Diproqualone, analogous to methaqualone, exhibits sedative, anxiolytic, anti-inflammatory, and analgesic properties [1].</p>Fórmula:C12H14N2O3Cor e Forma:SolidPeso molecular:234.255RAGE/SERT-IN-1
CAS:<p>RAGE/SERT-IN-1 is a potent, orally active inhibitor of advanced glycation end products (RAGE) and serotonin transporter (SERT), with IC50 values of 8.26 μM and</p>Fórmula:C38H41ClN4OSCor e Forma:SolidPeso molecular:637.28AAK1-IN-3
CAS:<p>AAK1-IN-3: Brain-penetrant AAK1 inhibitor for neuropathic pain research; IC50=11 nM.</p>Fórmula:C20H20N4Cor e Forma:SolidPeso molecular:316.4PNU109291
CAS:<p>PNU109291, a potent and selective agonist of the 5-HT1D receptor, effectively mitigates dural plasma extravasation induced by trigeminal ganglion stimulation.</p>Fórmula:C24H31N3O3Pureza:98%Cor e Forma:SolidPeso molecular:409.525-HT2C agonist-3 free base
CAS:<p>5-HT2C agonist-3 ((+)-19) free base, a selective 5-HT2C agonist (EC50: 24 nM, Ki: 78 nM), exhibits antipsychotic drug-like activity and inhibits Amphetamine-</p>Fórmula:C19H22FNO2Pureza:98%Cor e Forma:SolidPeso molecular:315.38BMS 433796
CAS:<p>BMS 433796 is a γ-secretase inhibitor that demonstrates Aβ-lowering activity within a transgenic mouse model of Alzheimer's disease.</p>Fórmula:C21H20F2N4O4Pureza:99.17%Cor e Forma:SolidPeso molecular:430.4TPA 023
CAS:<p>TPA 023 is a selective agonist of GABAA α2/α3 subtype (Kis = 0.19 - 0.41 nM).</p>Fórmula:C20H22FN7OPureza:99.75%Cor e Forma:SolidPeso molecular:395.43MIN-117
CAS:<p>MIN-117, a SSRI/5-HT receptor antagonist, is potentially used for the treatment of depression.</p>Fórmula:C25H26Cl3N3O4Pureza:98%Cor e Forma:SolidPeso molecular:538.85Dothiepin
CAS:<p>Dothiepin (Dosulepin; Dothep), an antidepressant with sedative/anxiolytic properties, preferentially inhibits noradrenaline over serotonin uptake, enhancing</p>Fórmula:C19H21NSPureza:98%Cor e Forma:SolidPeso molecular:295.44Frovatriptan
CAS:<p>Frovatriptan, potent 5-HT 1B/D agonist, shows high cerebroselectivity and efficacy for migraine with aura.</p>Fórmula:C14H17N3OCor e Forma:SolidPeso molecular:243.3L-AP4
CAS:<p>L-APB is an effective and specific agonist for the group III mGluRs (EC50s: 0.13, 0.29, 1.0, 249 μM for mGlu4, mGlu8, mGlu6, and mGlu7 receptors, respectively).</p>Fórmula:C4H10NO5PPureza:98%Cor e Forma:White To Off-White Crystalline PowderPeso molecular:183.1CGP36216 hydrochloride
CAS:<p>CGP36216 hydrochloride acts as a selective antagonist at the presynaptic GABA receptor, specifically binding to the GABAB receptor with a Ki value of 0.3 μM. This compound is leveraged in research focused on anxiety and trauma-related disorders [1] [2].</p>Fórmula:C5H15ClNO2PCor e Forma:SolidPeso molecular:187.6Thioflosulide
CAS:<p>Thioflosulide (L-745337) is a selective and potent COX2 inhibitor (IC50: 2.3 nM) with anti-inflammatory activity for the study of gastric ulcers.</p>Fórmula:C16H13F2NO3S2Pureza:>99.99%Cor e Forma:SolidPeso molecular:369.41mGAT3/4-IN-2
CAS:<p>mGAT3/4-IN-2 are potent inhibitors of mGAT3/mGAT4 with their pIC50 values of 5.44 and 5.25, respectively.</p>Fórmula:C26H32ClN3OS2Cor e Forma:SolidPeso molecular:502.13rel-HDMP 28 hydrochloride
CAS:<p>Rel-HDMP-28 hydrochloride (Compound 2g) is an analogue of methylphenidate, exhibiting selective affinity for the serotonin transporter (SERT) with a binding constant (Ki) of 105 nM [1].</p>Fórmula:C18H22ClNO2Cor e Forma:SolidPeso molecular:319.83Brasofensine Maleate
CAS:<p>Brasofensine Maleate inhibits the monoamine re-uptake.</p>Fórmula:C20H24Cl2N2O5Cor e Forma:SolidPeso molecular:443.32Brasofensine sulfate
CAS:<p>Brasofensine sulfate is a dopamine reuptake inhibitor.</p>Fórmula:C16H22Cl2N2O5SCor e Forma:SolidPeso molecular:425.33NO-711ME
CAS:<p>NO-711ME (N-O711 Methyl ester) is a prodrug of NO-711. It also is a potent and selective GABA uptake inhibitor.</p>Fórmula:C22H24N2O3Pureza:99.54%Cor e Forma:SolidPeso molecular:364.44N-Demethyl MK-6884
CAS:<p>N-Demethyl MK-6884 (compound 34) is an M4 mAChR modulator for Alzheimer's and related disease research.</p>Fórmula:C24H23N5OCor e Forma:SolidPeso molecular:397.47UNC9994
CAS:<p>UNC9994 is a β-arrestin-biased dopamine D₂ receptor agonist (β-arrestin EC50 = 50 nM; Emax = 97%) with robust in vivo antipsychotic drug-like activities.</p>Fórmula:C21H22Cl2N2OSCor e Forma:SolidPeso molecular:421.385-HT2 agonist-1 free base
CAS:<p>Compound 24 (5-HT2 agonist-1 free base) is a potent agonist for 5-HT2A, 5-HT2B, and 5-HT2C receptors, exhibiting IC50 values of 10 nM, 8.3 nM, and 1.6 nM,</p>Fórmula:C19H22N2O2Pureza:98%Cor e Forma:SolidPeso molecular:310.39ELND007
CAS:<p>ELND007 is a Gamma secretase inhibitor.</p>Fórmula:C19H14F4N4O2SCor e Forma:SolidPeso molecular:438.4CGP 54626 hydrochloride
CAS:<p>CGP 54626 hydrochloride is a GABAB receptor antagonist.</p>Fórmula:C18H29Cl3NO3PPureza:98%Cor e Forma:SolidPeso molecular:444.76CP-409092
CAS:<p>CP-409092 is a partial GABAA receptor agonist. It has anti-anxiety activity.</p>Fórmula:C17H19N3O2Pureza:98%Cor e Forma:SolidPeso molecular:297.35GABAA receptor agent 2 TFA
CAS:<p>Potent GABAA antagonist; IC50: 24 nM (α1β2γ2), Ki: 28 nM (rat); inactive on human GABA transporters.</p>Fórmula:C22H22F3N3O3Cor e Forma:SolidPeso molecular:433.425-HT2A antagonist 1
CAS:<p>5-HT2A antagonist 1, from US5728835A & JP 1007727, may treat gastrointestinal and circulatory issues.</p>Fórmula:C26H28N4O2Pureza:98%Cor e Forma:SolidPeso molecular:428.53Wf-516
CAS:<p>Wf-516 is a 5-HT reuptake inhibitor (Kis: 5 nM and 40 nM for 5-HT1A receptor and 5-HT2A receptor in humans, respectively), and with potent antidepressant</p>Fórmula:C25H25Cl2N3O4Pureza:98%Cor e Forma:SolidPeso molecular:502.395-HT2A&5-HT2C agonist-1
CAS:<p>5-HT2A&5-HT2C agonist-1 (Example 2) is a dual-acting agent targeting the 5-HT2A and 5-HT2C receptors with respective IC50 values of 196 nM and 0.9 nM.</p>Fórmula:C14H20N2OPureza:98%Cor e Forma:SolidPeso molecular:232.32DQP-26
CAS:<p>DQP-26, a potent negative allosteric modulator of NMDA receptors (NMDARs), exhibits IC50 values of 0.77 μM for GluN2C and 0.44 μM for GluN2D subunits,</p>Fórmula:C28H21Cl2N3O4Pureza:98%Cor e Forma:SolidPeso molecular:534.39QR-0217
CAS:<p>QR-0217 is a potent inhibitor of both Aβ1-40 and α-synuclein aggregation, exhibiting an IC50 of 7.5 µM for Aβ1-40.</p>Fórmula:C19H13NO3Cor e Forma:SolidPeso molecular:303.31GMA-839
CAS:<p>GMA-839 is a selective modulator of gamma-aminobutyric acid(A) receptors.</p>Fórmula:C21H31F3O3Pureza:98%Cor e Forma:SolidPeso molecular:388.46MAO-B-IN-19
CAS:<p>MAO-B-IN-19, a selective MAO-B inhibitor, exhibits neuroprotective and anti-inflammatory properties and demonstrates an IC50 value of 0.67 μM [1].</p>Fórmula:C15H11FO2Pureza:98%Cor e Forma:SolidPeso molecular:242.25GSM-1
CAS:<p>GSM-1 is a modulator of γ-Secretase.</p>Fórmula:C26H31ClF3NO2Cor e Forma:SolidPeso molecular:481.98Pomaglumetad methionil hydrochloride
CAS:<p>LY2140023 hydrochloride: oral methionine prodrug of LY404039, a selective mGlu2/3 agonist, studied for schizophrenia.</p>Fórmula:C12H19ClN2O7S2Pureza:98.57%Cor e Forma:SolidPeso molecular:402.87VU6012962
CAS:<p>VU6012962 is an orally bioavailable negative allosteric modulator of CNS-penetrant metabotropic glutamate receptor 7(mGlu7; IC50: 347 nM).</p>Fórmula:C21H19F3N4O4Pureza:99.61% - 99.74%Cor e Forma:SolidPeso molecular:448.4AChE-IN-30
CAS:<p>AChE-IN-30 is an acetylcholinesterase (AChE) inhibitor exhibiting neuroprotective effects with an inhibitory concentration (IC 50) of 4.4 μM.</p>Fórmula:C22H24N4O2Cor e Forma:SolidPeso molecular:376.45Muscarine tosylate
CAS:<p>Muscarine ((+)-Muscarine) tosylate, a prototype mAChR agonist, serves as a parasympathetic nervous system stimulant and is recognized for its toxic properties [1] [2].</p>Fórmula:C16H27NO5SCor e Forma:SolidPeso molecular:345.45Brasofensine
CAS:<p>Brasofensine, a benztoalkane MA reuptake inhibitor, shows promise for Parkinson's and Alzheimer's.</p>Fórmula:C16H20Cl2N2OCor e Forma:SolidPeso molecular:327.255-HT3 antagonist 1
CAS:<p>5-HT3 antagonist 1 is a potent and selective antagonist of 5-HT3 receptor.</p>Fórmula:C22H27N5OPureza:98%Cor e Forma:SolidPeso molecular:377.48VU0453595
CAS:<p>VU0453595 is a M1 positive allosteric modulator (PAM).</p>Fórmula:C18H15FN4OPureza:99.91%Cor e Forma:SolidPeso molecular:322.34Lanabecestat camsylate
CAS:<p>Lanabecestat camsylate is used as a BACE1 Inhibitor.</p>Fórmula:C36H44N4O5SPureza:98%Cor e Forma:SolidPeso molecular:644.83Gentisein
CAS:<p>Gentisein (NSC-329491), a primary metabolite of Mangiferin, exhibits significant inhibition of serotonin uptake, demonstrating potency with an IC50 value of 4.7</p>Fórmula:C13H8O5Pureza:96.89%Cor e Forma:SolidPeso molecular:244.24-Chloro-L-phenylalanine
CAS:<p>4-Chloro-L-phenalanine (L-PCPA) is an inhibitor of 5-HT biosynthesis and a non-specific antagonist of tryptophan hydroxylases (TPH1 and TPH2).</p>Fórmula:C9H10ClNO2Pureza:99.76% - 99.96%Cor e Forma:SolidPeso molecular:199.63Eslicarbazepine
CAS:<p>Eslicarbazepine (Stedesa) can be used for adjunctive therapy for adults with partial-onset seizures.</p>Fórmula:C15H14N2O2Pureza:99.97%Cor e Forma:Off-White SolidPeso molecular:254.28BMS-983970
CAS:<p>BMS-983970 is an oral inhibitor of pan-Notch, and for the treatment of multiplecancers.</p>Fórmula:C26H26F4N4O3Cor e Forma:SolidPeso molecular:518.5JNJ-46281222
CAS:<p>JNJ-46281222: mGlu2-selective, potent PAM, Kd = 1.7 nM, pEC50 = 7.71.</p>Fórmula:C23H25F3N4Cor e Forma:SolidPeso molecular:414.47Cimicoxib
CAS:<p>Cimicoxib (UR8880) is a potent and selective inhibitor of COX-2 with anti-inflammatory and analgesic activity.</p>Fórmula:C16H13ClFN3O3SPureza:98.22%Cor e Forma:SolidPeso molecular:381.81FPTQ
CAS:<p>FPTQ is a highly effective antagonist of mGluR 1, displaying IC50 values of 6 nM and 1.4 nM for human and mouse mGluR1 respectively [1].</p>Fórmula:C17H12FN5Pureza:99.68% - 99.88%Cor e Forma:SolidPeso molecular:305.31VU 0255035
CAS:<p>VU 0255035 is a highly selective, competitive and brain penetrant muscarinic M1 receptor antagonist with an IC50 of 130 nM.</p>Fórmula:C18H20N6O3S2Pureza:98.09% - 98.1%Cor e Forma:SolidPeso molecular:432.52NAS181
CAS:<p>rat 5-HT1B receptor antagonist</p>Fórmula:C21H34N2O10S2Pureza:98%Cor e Forma:SolidPeso molecular:538.63(+)-Bicuculline methiodide
CAS:<p>(+)-Bicuculline methiodide is a GABAA receptor blocker that blocks epileptogens and may be used in the study of neurological disorders.</p>Fórmula:C21H20INO6Pureza:99.24%Cor e Forma:SolidPeso molecular:509.29Mesembrine
CAS:<p>Mesembrine is an alkaloid, a 5-HT transporter inhibitor (K i 1.4 nM), and inhibits PDE4B (IC50 7.8 μM).</p>Fórmula:C17H23NO3Cor e Forma:SolidPeso molecular:289.37MAO-B-IN-1
CAS:<p>MAO-B-IN-1 is a monoamine oxidase B inhibitor and can be used for the research of neurological diseases.</p>Fórmula:C16H14F3N3O2SPureza:98%Cor e Forma:SolidPeso molecular:369.36GYKI-46903 HCl
CAS:<p>GYKI-46903 is a noncompetitive 5-HT3 receptor antagonist.</p>Fórmula:C17H21ClFNO2Cor e Forma:SolidPeso molecular:325.81LY3202626
CAS:<p>LY3202626, an amyloid precursor protein secretase (BACE protein) inhibitor, is used for the treatment of Alzheimer's disease.</p>Fórmula:C22H20F2N8O2SPureza:98%Cor e Forma:SolidPeso molecular:498.51YM348
CAS:<p>YM348 is an effective and orally active 5-HT2C receptor agonist. YM348 also shows a high affinity for the cloned human 5-HT2C receptor (Ki: 0.89 nM).</p>Fórmula:C14H17N3OPureza:98%Cor e Forma:SolidPeso molecular:243.3Fosthiazate
CAS:<p>Fosthiazate is a broad-spectrum nematicide that combats a range of plant parasitic nematodes such as Meloidogyne spp., Globodera spp., and Pratylenchus spp., by</p>Fórmula:C9H18NO3PS2Pureza:97.78%Cor e Forma:SolidPeso molecular:283.35(±)-Fabesetron hydrochloride
CAS:<p>FK1052 hydrochloride is a potent 5-HT3 and 5-HT4 receptor dual antagonist.</p>Fórmula:C18H20ClN3OPureza:98%Cor e Forma:SolidPeso molecular:329.82Benoxaprofen
CAS:<p>Benoxaprofen (NSC-299582) is a non-steroidal anti-inflammatory drug.</p>Fórmula:C16H12ClNO3Pureza:98.87%Cor e Forma:SolidPeso molecular:301.72LY-426965
CAS:<p>LY-426965 is a selective, potent, orally bioavailable 5-HT1A antagonist.</p>Fórmula:C28H38N2O2Cor e Forma:SolidPeso molecular:434.61(2R,4R)-APDC
CAS:<p>(2R,4R)-APDC is a selective group II metabotropic glutamate receptors (mGluRs) agonist. It has anticonvulsant and neuroprotective effects.</p>Fórmula:C6H10N2O4Pureza:98%Cor e Forma:SolidPeso molecular:174.15cis-PDA
CAS:<p>cis-PDA (cis PDA) is a general ionotropic receptor antagonist. cis-PDA acts by blocking NMDA, AMPA, and kainate-mediated responses.</p>Fórmula:C7H11NO4Pureza:98.71%Cor e Forma:White SolidPeso molecular:173.17Physostigmine hemisulfate
CAS:<p>cholinesterase inhibitor</p>Fórmula:C15H21N302H204SPureza:98%Cor e Forma:SolidPeso molecular:324.39β-Secretase Inhibitor IV
CAS:<p>β-Secretase Inhibitor IV is a potent, cell-active inhibitor of BACE-1(IC50s of 15.6 and 16.3nM under BACE-1 concentrations of 2 nM and 100 pM, respectively).</p>Fórmula:C31H38N4O5SPureza:98%Cor e Forma:SolidPeso molecular:578.72DU-125530
CAS:<p>DU-125530 is a 5-HT1A receptor antagonist.</p>Fórmula:C23H26ClN3O5SCor e Forma:SolidPeso molecular:491.99Aβ/tau aggregation-IN-3
CAS:<p>Aβ/tau aggregation-IN-3 is a potent inhibitor of amyloid protein aggregation, exhibiting an IC50 value of 0.85 µM in an Aβ-Thioflavin T (Aβ-ThT) functional</p>Fórmula:C23H22N4O3Cor e Forma:SolidPeso molecular:402.455-HT2 agonist-1
CAS:<p>Compound 24, a 5-HT2 agonist-1, selectively activates 5-HT2A, 5-HT2B, and 5-HT2C receptors with IC50 values of 10 nM, 8.3 nM, and 1.6 nM, respectively.</p>Fórmula:C19H23ClN2O2Pureza:98%Cor e Forma:SolidPeso molecular:346.853-Bromocytisine
CAS:<p>3-Bromocytisine ((-)-3-Bromocytisine) is an effective agonist of nAChR (IC50s: 0.28, 0.30 and 31.6 nM for hα4β4, hα4β2, and hα7).</p>Fórmula:C11H13BrN2OPureza:99.974%Cor e Forma:SolidPeso molecular:269.14(1α,1'S,4β)-Lanabecestat
CAS:<p>(1α,1'S,4β)-Lanabecestat is a Beta site APP Cleaving Enzymel (BACE1) inhibitor, and has IC50s of 2.2 nM (TR-FRET assay) and 0.28 nM (sAPPp release assay),</p>Fórmula:C26H28N4OCor e Forma:SolidPeso molecular:412.53MTPG
CAS:<p>Group II/group III metabotropic glutamate receptor antagonist</p>Fórmula:C10H11N5O2Pureza:98%Cor e Forma:SolidPeso molecular:233.235-HT2C agonist-3
CAS:<p>5-HT2C agonist-3 ((+)-19), a selective 5-HT2C agonist (EC 50: 24 nM, Ki: 78 nM), exhibits antipsychotic-like activity by blocking amphetamine-induced</p>Fórmula:C19H23ClFNO2Pureza:98%Cor e Forma:SolidPeso molecular:351.84mAChR antagonist 1
CAS:<p>Compound 4a, a mAChR antagonist, exhibits K i values of 255 nM for M1 and M5 subtypes, and lower values of 121 nM and 158 nM for M3 and M4 subtypes,</p>Fórmula:C19H22N2O2Cor e Forma:SolidPeso molecular:310.39Pregnanolone sulfate (pyridinium)
CAS:<p>Pregnanolone sulfate pyridinium, an endogenous neurosteroid, inhibits NMDA receptors and exhibits neuroprotective properties [1].</p>Fórmula:C26H39NO5SPureza:98%Cor e Forma:SolidPeso molecular:477.66(S)-Bexicaserin
CAS:<p>(S)-Bexcaserin (compound 2) serves as a 5-HT2C receptor agonist, presenting research possibilities in obesity and psychiatric disorders [1].</p>Fórmula:C15H19F2N3OPureza:98%Cor e Forma:SolidPeso molecular:295.33COR659
CAS:<p>COR659: suppresses alcohol/chocolate intake in rats; enhances GABAB receptor, blocks CB1 receptor.</p>Fórmula:C16H16ClNO3SPureza:99.75%Cor e Forma:SolidPeso molecular:337.82AChE-IN-31
CAS:<p>AChE-IN-31 (compound 1), a non-competitive acetylcholinesterase (AChE) inhibitor, exhibits potential for Alzheimer's disease research [1].</p>Fórmula:C27H44Na2O9S2Cor e Forma:SolidPeso molecular:622.74BACE1-IN-13
CAS:<p>BACE1-IN-13 (Compound 36), an orally active inhibitor of BACE1, exhibits high potency with an IC50 of 2.9 nM and demonstrates greater efficacy in hAβ42 cells (</p>Fórmula:C20H17FN8O2Pureza:98%Cor e Forma:SolidPeso molecular:420.4MAO-IN-3
CAS:<p>MAO-IN-3 (Compound 5), a reversible and competitive monoamine oxidase (MAO) inhibitor with inhibition constants (K i) of 0.6 μM for MAO A and 0.2 μM for MAO B,</p>Fórmula:C42H54N4O4Pureza:98%Cor e Forma:SolidPeso molecular:678.9Nevadistinel
CAS:<p>Nevadistinel (NYX-458; NYX-3054) is a positive allosteric modulator of the N-methyl-D-aspartate (NMDA) receptor, indicated for mitigating cognitive deficits</p>Fórmula:C15H18N2O3Pureza:98%Cor e Forma:SolidPeso molecular:274.32AAK1-IN-4
CAS:<p>AAK1-IN-4 selectively inhibits AAK1 with IC50 of 4.6 nM; penetrates CNS, oral bioactive, potential for studying neuropathic pain.</p>Fórmula:C20H28N4O3Cor e Forma:SolidPeso molecular:372.46R-96544
CAS:<p>R-96544 is an orally active antagonist of the 5-HT2A receptor that has demonstrated the ability to inhibit platelet aggregation in vitro [1].</p>Fórmula:C22H30ClNO3Cor e Forma:SolidPeso molecular:391.93(-)-Bicuculline methochloride
CAS:<p>(-)-Bicuculline methochloride is a potent antagonist of GABAA receptor.</p>Fórmula:C21H20ClNO6Pureza:98%Cor e Forma:SolidPeso molecular:417.84AAK1-IN-5
CAS:<p>AAK1-IN-5: Potent, selective AAK1 inhibitor; CNS-penetrant; oral; IC50: 1.2 nM; Ki: 0.05 nM; cell IC50: 0.5 nM. Useful in neuropathic pain research.</p>Fórmula:C19H23F4N3OCor e Forma:SolidPeso molecular:385.4Quinolactacin A1
CAS:<p>Quinolactacin A1, a strong AChE inhibitor from Penicillium citrinum, aids Alzheimer's research.</p>Fórmula:C16H18N2O2Cor e Forma:SolidPeso molecular:270.33QM-FN-SO3
CAS:<p>QM-FN-SO3 is a blood-brain barrier (BBB)-penetrable, near-infrared (NIR) probe with aggregation-induced emission (AIE) activity, specifically designed for the detection of Aβ plaques. It exhibits ultra-high signal-to-noise (S/N) ratio, binding affinity, and high-performance NIR emission, making it suitable for in vivo detection of Aβ plaques [1].</p>Fórmula:C29H25N4NaO3S2Cor e Forma:SolidPeso molecular:564.65Octahydroaminoacridine succinate
CAS:<p>Octahydroaminoacridine succinate, an acetylcholinesterase inhibitor, is used potentially for the treatment of Alzheimer's disease.</p>Fórmula:C17H24N2O4Pureza:99.91%Cor e Forma:SolidPeso molecular:320.38BMS-932481
CAS:<p>BMS-932481 is a γ-secretase modulator.</p>Fórmula:C24H24FN7OCor e Forma:SolidPeso molecular:445.49Biphenylindanone A
CAS:<p>Biphenylindanone A is a selective potentiator of human mGluR2 (hmGluR2),and for the treatment of neurological disorders.</p>Fórmula:C30H30O4Pureza:98%Cor e Forma:SolidPeso molecular:454.56Anti-amyloid agent-1
CAS:<p>Anti-amyloid agent-1 is a potent compound that inhibits amyloid aggregation, offering a promising approach for research into the treatment of amyloidosis [1].</p>Fórmula:C21H17F3N2O3Cor e Forma:SolidPeso molecular:402.37Abaperidone
CAS:<p>Abaperidone is an atypical antipsychotic, antagonizes 5-HT2A (IC50=6.2 nM) and D2 receptors (IC50=17 nM), reduces hsp70 mRNA in rat brains.</p>Fórmula:C25H25FN2O5Pureza:98.22%Cor e Forma:SolidPeso molecular:452.47BChE-IN-20
CAS:<p>BChE-IN-20 (compound 7c) is a potent, selective inhibitor of BChE, demonstrating IC50 values of 105 nM for eqBChE and 2.3 nM for hBChE.</p>Fórmula:C27H39N5O2Cor e Forma:SolidPeso molecular:465.63MGS-0039
CAS:<p>MGS-0039: Group II mGluR2/3 antagonist, non-serotonergic antidepressant-like effect, AMPA involvement, regulates dopamine in NAc.</p>Fórmula:C15H14Cl2FNO5Pureza:98%Cor e Forma:SolidPeso molecular:378.18AAK1-IN-2
CAS:<p>AAK1-IN-2, a potent (IC50=5.8 nM) AAK1 inhibitor, selective & brain-penetrant, is used for neuropathic pain studies.</p>Fórmula:C20H20N4Cor e Forma:SolidPeso molecular:316.4CAY10649
CAS:<p>1CAY10649, a thiazolinone compound, directly inhibits 5-lipoxygenase (5-LO) product formation in intact polymorphonuclear leukocytes (PMNL) with an IC50 value of 0.28 μM and in a soluble fraction of an S100 PMNL cell lysate with an IC50 value of 0.09 μM, following stimulation by calcium and arachidonic acid. This activity highlights its potential in mitigating inflammatory responses by targeting the biosynthesis of leukotrienes, substances implicated in various inflammatory processes such as neutrophil chemotaxis, increased vascular permeability, and smooth muscle contraction.</p>Fórmula:C17H12ClNO2SCor e Forma:SolidPeso molecular:329.8Timepidium bromide
CAS:<p>Timepidium bromide is an agent of anticholinergic.</p>Fórmula:C17H22BrNOS2Pureza:98%Cor e Forma:SolidPeso molecular:400.4Robalzotan
CAS:<p>Robalzotan is a selective 5-HT1A receptor antagonist.</p>Fórmula:C18H23FN2O2Pureza:98%Cor e Forma:SolidPeso molecular:318.39Tiotropium Bromide hydrate
CAS:<p>Tiotropium Bromide hydrate is a potent, long-lasting anticholinergic bronchodilator for COPD, with high affinity for muscarinic receptors M1, M2, and M3.</p>Fórmula:C19H24BrNO5S2Pureza:98.44% - 99.41%Cor e Forma:SolidPeso molecular:490.43FPPQ
CAS:<p>FPPQ blocks 5-HT3 and 5-HT6 receptors (Ki: 0.9 & 3 nM) and may improve psychosis and cognition.</p>Fórmula:C21H19FN4O2SCor e Forma:SolidPeso molecular:410.46ABT-418 hydrochloride
CAS:<p>ABT-418 HCl enhances cognition and reduces anxiety as a selective nAChRs agonist, researched for Alzheimer's.</p>Fórmula:C9H15ClN2OCor e Forma:SolidPeso molecular:202.68Brilaroxazine
CAS:<p>Brilaroxazine (RP5063): multimodal dopamine/5-HT modulator, partial agonist at D2/D3/D4, 5-HT1A/2A, and antagonist at 5-HT2B/7.</p>Fórmula:C22H25Cl2N3O3Pureza:99.36%Cor e Forma:SolidPeso molecular:450.36Befiradol
CAS:<p>Befiradol (NLX-112) is an agonist of 5-HT1A receptor.</p>Fórmula:C20H22ClF2N3OCor e Forma:SolidPeso molecular:393.86LY108742
CAS:<p>LY108742 is an antagonist of 5-HT2.</p>Fórmula:C21H28N2O3Pureza:98%Cor e Forma:SolidPeso molecular:356.46C3
CAS:<p>C3 functions as a selective inhibitor of monoamine oxidase B (MAO-B; IC50= 0.021 µM), demonstrating preference over monoamine oxidase A (MAO-A; IC50= 26.8 µM). This compound, at dosages of 0.1, 1, and 3 mg/kg, effectively counters MPTP-induced reductions in dopamine levels within the mouse brain.</p>Fórmula:C18H19FN2O2Cor e Forma:SolidPeso molecular:314.35Cyclophostin
CAS:<p>Cyclophostin is an irreversible inhibitor of acetylcholinesterase (AChE).</p>Fórmula:C8H11O6PPureza:98%Cor e Forma:SolidPeso molecular:234.14P2X3-IN-1
CAS:<p>P2X3-IN-1 (example 7) is a P2X3 receptor inhibitor suitable for research on neurogenic diseases [1].</p>Fórmula:C22H21FN8O3Pureza:98%Cor e Forma:SolidPeso molecular:464.45Indeloxazine hydrochloride
CAS:<p>Indeloxazine HCl: Serotonin releaser, NE reuptake inhibitor, NMDA antagonist; antidepressant that boosts acetylcholine in rats.</p>Fórmula:C14H18ClNO2Pureza:98%Cor e Forma:SolidPeso molecular:267.75Adipiplon
CAS:<p>Adipiplon(NG2-73, NG273) is a novel selective gamma-aminobutyric acid (GABA) partial agonist.</p>Fórmula:C18H18FN7Cor e Forma:SolidPeso molecular:351.38CGP 64213
CAS:<p>CGP 64213 is a GABAb receptor agonist.</p>Fórmula:C26H36IN2O7PPureza:98%Cor e Forma:SolidPeso molecular:646.45U 89843A
CAS:<p>U 89843A is a positive allosteric modulator of gamma-aminobutyric acid (GABA)A receptors.</p>Fórmula:C16H23N5Pureza:99.62%Cor e Forma:SolidPeso molecular:285.39BT-GSI
<p>BT-GSI: γ-secretase inhibitor targeting Notch, anti-myeloma & anti-resorptive for multiple myeloma/bone disease research.</p>Fórmula:C26H46BrN5O10P2Cor e Forma:SolidPeso molecular:730.52Facinicline hydrochloride
CAS:<p>Facinicline hydrochloride (RG3487) is both a novel nicotinic alpha-7 receptor (alpha7nAChR) partial agonist (Ki = 6 nM) and an antagonist of 5-HT3(Ki = 1.2 nM).</p>Fórmula:C15H19ClN4OPureza:98.70%Cor e Forma:SolidPeso molecular:306.79Zamifenacin fumarate
CAS:<p>Zamifenacin fumarate (UK-76654 fumarate) is a potent and gut-selective antagonist of muscarinic M3 receptor.</p>Fórmula:C31H33NO7Pureza:99.88%Cor e Forma:SolidPeso molecular:531.65-HT3-In-1
CAS:<p>5-HT3-In-1 (compound example 8) exhabits with 5-HT3 inhibition activity.</p>Fórmula:C16H21ClN4O3Pureza:98%Cor e Forma:SolidPeso molecular:352.82eeAChE-IN-2
CAS:<p>eeAChE-IN-2 is a potent inhibitor of eeAChE, exhibiting inhibitory potency with an IC50 of 2 nM.</p>Fórmula:C37H40N8O5SCor e Forma:SolidPeso molecular:708.83L 687306
CAS:<p>L 687306 is a partial agonist of muscarinic M1 receptors. It is also a highly competitive antagonist at cardiac M2 receptors and ileal M3 muscarinic receptors.</p>Fórmula:C11H15N3OCor e Forma:SolidPeso molecular:205.26GR 127935 hydrochloride
CAS:<p>5-HT1B/1D receptor antagonist</p>Fórmula:C29H32ClN5O3Pureza:98%Cor e Forma:SolidPeso molecular:534.05AMG-8718
CAS:<p>AMG-8718, an oral BACE1 blocker (IC50: 0.0007 μM), also inhibits BACE2 (IC50: 0.005 μM), lowering CSF and Aβ40 brain levels.</p>Fórmula:C25H19FN4O3Cor e Forma:SolidPeso molecular:442.44NAS-181
CAS:<p>NAS-181 is a potent and selective rat 5-hydroxytryptamine 1B (r5-HT1B) antagonist (Ki: 47 nM).NAS-181 enhances the accumulation of 5-HTP in rat brain regions.</p>Fórmula:C20H30N2O7SCor e Forma:SolidPeso molecular:442.53NAD 299 hydrochloride
CAS:<p>Selective, high affinity 5-HT1A receptor antagonist</p>Fórmula:C18H24ClFN2O2Pureza:98%Cor e Forma:SolidPeso molecular:354.85CGP 55845 hydrochloride
CAS:<p>CGP55845 hydrochloride is a potent and selective GABAB receptor antagonist with an IC 50 of 6 nM which can be used in neurological research [1] [2].</p>Fórmula:C18H23Cl3NO3PCor e Forma:SolidPeso molecular:438.71FGIN-1-27
CAS:<p>FGIN-1-27 is a high-affinity agonist of the translocator protein and a specific peripheral benzodiazepine receptor (PBR) ligand(Ki = 5.0 nM).</p>Fórmula:C28H37FN2OPureza:99.86%Cor e Forma:SolidPeso molecular:436.6BMS-933043
CAS:<p>BMS-933043: α7 nAChR partial agonist, binds rat (Ki=3.3 nM) & human (Ki=8.1 nM), agonist with EC50=23.4 nM (calcium assay), 0.14-0.29 μM (electrophysiology).</p>Fórmula:C16H19N7OPureza:98%Cor e Forma:SolidPeso molecular:325.37LG 50643
CAS:<p>LG 50643 is a muscarinic antagonist.</p>Fórmula:C24H34INO2Pureza:98%Cor e Forma:SolidPeso molecular:495.44BACE1-IN-1
CAS:<p>BACE1-IN-1 is a high brain penetrant BACE1 inhibitor (IC50s: 32 and 47 nM for human BACE1 and BACE2).</p>Fórmula:C18H14F3N5O2Pureza:98%Cor e Forma:SolidPeso molecular:389.33
