CymitQuimica logo
Neurociência

Neurociência

Os inibidores de neurociência são compostos projetados para modular a atividade de proteínas, enzimas ou receptores específicos no sistema nervoso. Esses inibidores são cruciais para estudar os mecanismos moleculares subjacentes à função neural, transmissão sináptica e doenças neurodegenerativas. Ao direcionar receptores de neurotransmissores, canais iônicos e vias de sinalização, os inibidores de neurociência ajudam na exploração da função cerebral e no desenvolvimento de estratégias terapêuticas para distúrbios neurológicos como Alzheimer, Parkinson e epilepsia. Na CymitQuimica, oferecemos uma ampla gama de inibidores de neurociência de alta qualidade para apoiar sua pesquisa em neurobiologia, neurofarmacologia e ciências cognitivas.

Subcategorias de "Neurociência"

Exibir 12 mais subcategorias

Foram encontrados 5400 produtos de "Neurociência"

Ordenar por
Pureza (%)
0
100
|
0
|
50
|
90
|
95
|
100
produtos por página.
  • P2X7 receptor antagonist-5
    Targetmol
    + Info

    P2X7 receptor antagonist-5

    CAS:
    <p>P2X7 receptor antagonist-5 (compound 13a) is a potent, orally active, and long-lasting antagonist of the P2X7 receptor.</p>
    Fórmula:C21H17F3N6O3S2
    Cor e Forma:Solid
    Peso molecular:522.52

    Ref: TM-T201089

  • LY 215840
    Targetmol
    + Info

    LY 215840

    CAS:
    <p>5-HT2/5-HT7 receptor antagonist</p>
    Fórmula:C24H33N3O2
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:395.54

    Ref: TM-T22940

  • PXS-4787 hydrochloride
    Targetmol
    + Info

    PXS-4787 hydrochloride

    CAS:
    <p>PXS-4787 hydrochloride is a specific and potent pan-lysyl oxidase inhibitor that effectively eliminates the activity of lysyl oxidase. It exhibits varying IC50 values against different forms of the enzyme, including 2 μM (Bovine LOX), 3.2 μM (rh LOXL1), 0.6 μM (rh LOXL2), 1.4 μM (rh LOXL3), and 0.2 μM (rh LOXL4). In addition, PXS-4787 hydrochloride reduces the deposition and cross-linking of collagen I secreted by human fibroblasts.</p>
    Fórmula:C10H13ClFNO2S
    Cor e Forma:Solid
    Peso molecular:265.73

    Ref: TM-T201314

  • 5-HT7R antagonist 3
    Targetmol
    + Info

    5-HT7R antagonist 3

    CAS:
    <p>Compound 6.4, also known as 5-HT7R antagonist 3, is a selective antagonist of the 5-HT7R with a Ki of 8 nM. It exhibits significantly less affinity towards D2R, 5-HT1AR, and 5-HT2AR with Ki values of 511 nM, 8930 nM, and 5786 nM, respectively. In mice, 5-HT7R antagonist 3 demonstrates anti-depressant and anti-anxiety activities.</p>
    Fórmula:C30H33FN4O3
    Cor e Forma:Solid
    Peso molecular:516.61

    Ref: TM-T201849

  • HW161023
    Targetmol
    + Info

    HW161023

    CAS:
    <p>HW161023 (compound) is an orally active inhibitor of AP2 associated protein kinase 1 (AAK1), exhibiting IC50 values of 5.4 nM for AAK1 and 11.9 μM for hERG. HW161023 can suppress pain response in a rat model of chronic sciatic nerve compression injury.</p>
    Fórmula:C20H24F2N4O
    Cor e Forma:Solid
    Peso molecular:374.428

    Ref: TM-T206896

  • R-96544 hydrochloride
    Targetmol
    + Info

    R-96544 hydrochloride

    CAS:
    <p>5-HT2 receptor antagonist</p>
    Fórmula:C22H29NO3
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:355.47

    Ref: TM-T23219

  • PTCA
    Targetmol
    + Info

    PTCA

    CAS:
    <p>PTCA is a potent ligand for Ca2+/calmodulin-dependent protein kinase II α (CaMKIIα), with a pKi value of 7.2.</p>
    Fórmula:C10H5Cl2NO2S
    Cor e Forma:Solid
    Peso molecular:274.123

    Ref: TM-T204835

  • Pomaglumetad methionil
    Targetmol
    + Info

    Pomaglumetad methionil

    CAS:
    <p>Pomaglumetad methionil is an oral methionine prodrug of the potent specific agonist of mGlu2/3 receptor LY404039.</p>
    Fórmula:C12H20N2O8S2
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:384.43

    Ref: TM-T12520

  • UB 165
    Targetmol
    + Info

    UB 165

    CAS:
    <p>Subtype-selective nicotinic agonist</p>
    Fórmula:C13H15ClN2
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:234.72

    Ref: TM-T23485

  • Logotipo do CymitQuimica
    Targetmol
    + Info

    BChE-IN-3

    <p>BChE-IN-3: Selective, pseudo-irreversible BChE inhibitor (IC50: 56.9 nM); borderline reversible AChE inhibitor.</p>
    Fórmula:C26H41N3O2
    Cor e Forma:Solid
    Peso molecular:427.62

    Ref: TM-T62336

  • Fletazepam
    Targetmol
    + Info

    Fletazepam

    CAS:
    <p>Fletazepam, a benzodiazepine derivative, exhibits sedative, anti-anxiety, and muscle-relaxant properties. It is utilized in neurological research.</p>
    Fórmula:C17H13ClF4N2
    Cor e Forma:Solid
    Peso molecular:356.74

    Ref: TM-T201147

  • LOXL2-IN-1 tosylate
    Targetmol
    + Info

    LOXL2-IN-1 tosylate

    <p>LOX-IN-5 tosylate (compound 22) is a selective oral inhibitor of lysyl oxidase-like 2 (LOXL2) with an IC50 of less than 300 nM, and it exhibits anti-fibrotic properties.</p>
    Fórmula:C28H33FN4O5S2
    Cor e Forma:Solid
    Peso molecular:588.714

    Ref: TM-T205044

  • MAO-A inhibitor 3
    Targetmol
    + Info

    MAO-A inhibitor 3

    CAS:
    <p>MAO-A inhibitor3 (Compound 360) is an MAO-A inhibitor with an IC50 greater than 100 μM. It is utilized in the investigation of neurological disorders.</p>
    Fórmula:C11H8O5
    Cor e Forma:Solid
    Peso molecular:220.178

    Ref: TM-T205117

  • hAChE-IN-10
    Targetmol
    + Info

    hAChE-IN-10

    CAS:
    <p>hAChE-IN-10 (Compound ET11) is an inhibitor of human acetylcholinesterase (AChE) with an IC50 of 6.34 nM. This compound is capable of scavenging free radicals and exhibits antioxidant activity. Additionally, hAChE-IN-10 demonstrates metal-chelating properties, inhibiting Cu2+-induced Aβ1-42 aggregation, reducing amyloid plaque formation, and offering neuroprotective effects. It also ameliorates cognitive impairment in mice induced by Scopolamine.</p>
    Fórmula:C25H24ClFN6O2
    Cor e Forma:Solid
    Peso molecular:494.948

    Ref: TM-T204876

  • Ro4368554
    Targetmol
    + Info

    Ro4368554

    CAS:
    <p>Ro4368554 is a selective 5-HT6 antagonist capable of crossing the blood-brain barrier. It can reverse memory deficits caused by scopolamine and tryptophan depletion. Ro4368554 is applicable for research related to memory impairments.</p>
    Fórmula:C19H21N3O2S
    Cor e Forma:Solid
    Peso molecular:355.454

    Ref: TM-T204915

  • GABA-IN-4
    Targetmol
    + Info

    GABA-IN-4

    CAS:
    <p>GABA-IN-4 (Compound 17) is a derivative of N-(indol-3-ylglyoxylyl)benzylamine. It exhibits high affinity for the benzodiazepine receptor (BzR), the binding site within the GABAA receptor complex, with a Ki value of 67 nM. Benzodiazepines are widely used as anxiolytic, sedative-hypnotic, and anticonvulsant agents.</p>
    Fórmula:C17H13ClN2O2
    Cor e Forma:Solid
    Peso molecular:312.75

    Ref: TM-T205501

  • BF-168
    Targetmol
    + Info

    BF-168

    CAS:
    <p>BF-168 is a candidate probe for PET and specifically recognizes both neuritic and diffuse plaques (Ki: 6.4 nM for Aβ1-42).</p>
    Fórmula:C18H17FN2O2
    Cor e Forma:Solid
    Peso molecular:312.34

    Ref: TM-T10529

  • 5-IAI hydrochloride
    Targetmol
    + Info

    5-IAI hydrochloride

    CAS:
    <p>5-IAI hydrochloride is a psychoactive analog of para-iodoamphetamine. 5-IAI hydrochloride significantly reduces serotonin uptake sites and hippocampal serotonin levels in rats.</p>
    Fórmula:C9H11ClIN
    Cor e Forma:Solid
    Peso molecular:295.548

    Ref: TM-T204949

  • Aβ42-IN-1
    Targetmol
    + Info

    Aβ42-IN-1

    CAS:
    <p>Aβ42-IN-1, compound 1v, is a novel, potent and orally active γ-secretase modulator (GSM).</p>
    Fórmula:C29H27ClN4O2
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:499

    Ref: TM-T10211

  • (R)-Norfluoxetine
    Targetmol
    + Info

    (R)-Norfluoxetine

    CAS:
    <p>(R)-Norfluoxetine is the (R)-enantiomer of Norfluoxetine. It functions as a potent serotonin reuptake inhibitor, with a Ki value of 13 nM. This compound is utilized in the research of depression.</p>
    Fórmula:C16H16F3NO
    Cor e Forma:Solid
    Peso molecular:295.299

    Ref: TM-T204202