Receptor 5-HT
Os receptores 5-HT, também conhecidos como receptores de serotonina, são um grupo de receptores acoplados à proteína G (GPCRs) que mediam os efeitos da serotonina, um neurotransmissor envolvido na regulação do humor, ansiedade, sono, apetite e outros processos fisiológicos. Esses receptores são divididos em vários subtipos, cada um com funções e propriedades farmacológicas distintas. Moduladores de receptores 5-HT são amplamente estudados por seus papéis no tratamento da depressão, distúrbios de ansiedade e outras condições neuropsiquiátricas. Na CymitQuimica, oferecemos uma variedade de moduladores de receptores 5-HT de alta qualidade para apoiar sua pesquisa em neurofarmacologia, transtornos do humor e sinalização GPCR.
Foram encontrados 940 produtos de "Receptor 5-HT"
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Amitriptyline
CAS:<p>Amitriptyline: a tricyclic antidepressant used for depression and neuropathic pain.</p>Fórmula:C20H23NPureza:98.24% - 99.64%Cor e Forma:Crystals SolidPeso molecular:277.4Quipazine
CAS:<p>Quipazine: 5-HT agonist, Ki 1.4 nM at 5-HT3R, anti-SARS-CoV-2 (EC50 31.64 μM), for neurological research.</p>Fórmula:C13H15N3Cor e Forma:SolidPeso molecular:213.28SR 57227 hydrochloride
CAS:<p>SR 57227A (SR 57227 hydrochloride) is a potent, orally active and selective 5-HT3 receptor agonist. It with ability to cross the blood brain barrier.</p>Fórmula:C10H14ClN3·HClPureza:99.89%Cor e Forma:SolidPeso molecular:248.15Ramosetron
CAS:<p>Ramosetron 是一种血清素 5-HT3 受体拮抗剂，用于治疗恶心和呕吐。它被认为比其他一代 5-HT3 拮抗剂如昂丹司琼具有更高的效力和更长的止吐作用。它还适用于治疗“男性以腹泻为主的肠易激综合征”。它仅获准在日本和选定的东南亚国家使用。</p>Fórmula:C17H17N3OPureza:98.84%Cor e Forma:SolidPeso molecular:279.34Brexpiprazole HCl
CAS:<p>Brexpiprazole HCl (OPC 34712 dihydrochloride) is a new antipsychotic drug.</p>Fórmula:C25H27N3O2S·xHClPureza:99.05%Cor e Forma:SolidPeso molecular:433.6Ziprasidone mesylate
CAS:<p>Ziprasidone mesylate (CP-88059), an oral 5-HT & dopamine blocker, binds D2, 5-HT2A, 5-HT1A with Ki values: 4.8, 0.42, 3.4 nM.</p>Fórmula:C22H25ClN4O4S2Cor e Forma:SolidPeso molecular:509.04Tiprenolol
CAS:<p>Tiprenolol is a beta adrenergic receptor antagonist.[1]</p>Fórmula:C13H21NO2SPureza:99.43%Cor e Forma:SolidPeso molecular:255.38Tandospirone hydrochloride
CAS:<p>Tandospirone (SM-3997) HCl: potent 5-HT1A partial agonist; Ki: 27 nM; anxiolytic, antidepressant, for CNS disorder research.</p>Fórmula:C21H30ClN5O2Cor e Forma:SolidPeso molecular:419.95γ-Mangostin
CAS:<p>Gamma-Mangostin (Normangostin) has free radical scavenging activity, and antiproliferative and apoptotic activity. Gamma-Mangostin is an antihypertensive agent.</p>Fórmula:C23H24O6Pureza:98.55% - 99.08%Cor e Forma:SolidPeso molecular:396.43Nelotanserin
CAS:<p>Nelotanserin (APD125): strong 5-HT2A inverse agonist (IC50: 1.7 nM), moderate 5-HT2C (79 nM), weak 5-HT2B (791 nM).</p>Fórmula:C18H15BrF2N4O2Pureza:98.42% - 99.88%Cor e Forma:SolidPeso molecular:437.24Xanthotoxol
CAS:<p>Xanthotoxol (Psoralen) is a bioactive furocoumarin with anti-inflammatory, antioxidant, 5-HT antagonist, and neuroprotective properties.</p>Fórmula:C11H6O4Pureza:99.97%Cor e Forma:SolidPeso molecular:202.161-(1-Naphthyl) piperazine hydrochloride
CAS:<p>1-(1-Naphthyl) piperazine hydrochloride (1-naphthalen-1-ylpiperazine hydrochloride) is a serotonergic ligand which could bind nonselectively with multiple</p>Fórmula:C14H17ClN2Pureza:98.27%Cor e Forma:SolidPeso molecular:248.75Tropisetron
CAS:<p>Tropisetron (ICS 205-930) is an α7-nicotinic receptor agonist and 5-HT3 receptor antagonist with Kis of 6.9 nM and 5.3 nM, respectively.</p>Fórmula:C17H20N2O2Pureza:99.68%Cor e Forma:White SolidPeso molecular:284.35ARC-239
CAS:<p>ARC-239 is an agonist of α2-adrenergic receptor.</p>Fórmula:C24H29N3O3Cor e Forma:SolidPeso molecular:407.51Aripiprazole monohydrate
CAS:<p>Aripiprazole (OPC-14597) is a potent D2 partial agonist and inverse agonist of 5-HT2 receptors, used for schizophrenia and COVID-19 studies.</p>Fórmula:C23H29Cl2N3O3Cor e Forma:SolidPeso molecular:466.4MDL 100009
CAS:<p>MDL 100009, the S-enantiomer of MDL 100151 and the opposite enantiomer of MDL 100907, is a selective antagonist of 5-HT2A.</p>Fórmula:C22H28FNO3Pureza:98.96%Cor e Forma:SolidPeso molecular:373.46Relenopride hydrochloride
CAS:<p>Relenopride, a 5-HT agonist, is used potentially for the treatment of chronic constipation.</p>Fórmula:C24H31Cl2FN4O4Cor e Forma:SolidPeso molecular:529.43Geissoschizine methyl ether
CAS:<p>Geissoschizine methyl ether: an alkaloid from Uncaria hook, key in Yokukansan, impacts mood and social behavior enhancing serotonin activity.</p>Fórmula:C22H26N2O3Pureza:99.24% - 99.68%Cor e Forma:SolidPeso molecular:366.45Harmine
CAS:<p>Harmine (Telepathine) is an alkaloid isolated from seeds of Peganum harmala.</p>Fórmula:C13H12N2OPureza:98.29% - 99.92%Cor e Forma:Off-White SolidPeso molecular:212.25Metadoxine
CAS:<p>Metadoxine (Metadoxil) is a neurotransmitter stimulant.</p>Fórmula:C8H11NO3·C5H7NO3Pureza:99.19%Cor e Forma:Off-White PowderPeso molecular:298.29Clozapine HCl
CAS:<p>Clozapine HCl, an atypical antipsychotic, binds CNS receptors, targets 5-HT2A/2C, has weaker D2 antagonism. Risk: Agranulocytosis.</p>Fórmula:C18H20Cl2N4Cor e Forma:SolidPeso molecular:363.29Brexpiprazole
CAS:<p>Brexpiprazole (OPC-34712) is a partial agonist of human 5-hydroxytryptamine (5-HT) 5-HT1A and dopamine D2 receptors.</p>Fórmula:C25H27N3O2SPureza:99.06% - 99.96%Cor e Forma:SolidPeso molecular:433.57Sevoflurane
CAS:<p>Sevoflurane (Fluoromethyl), a noncompetitive inhibitor of 5-HT3 receptor, acts as a low-soluble inhalation anesthetics.</p>Fórmula:C4H3F7OPureza:98%Cor e Forma:Less Oil Colorless OilPeso molecular:200.05Perospirone
CAS:<p>Perospirone (Lullan) is an antagonist of serotonin 5HT2A receptors and dopamine D2 receptors.</p>Fórmula:C23H30N4O2SPureza:99.23%Cor e Forma:White PowderPeso molecular:426.57Frovatriptan Succinate
CAS:<p>Frovatriptan Succinate is a synthetic triptan with 5-HT1B/1D receptors agonist activity. It is indicated for the acute treatment of migraine.</p>Fórmula:C18H25N3O6Cor e Forma:SolidPeso molecular:379.41SB399885
CAS:<p>SB399885 is a potent, brain-penetrant, oral SR-6 antagonist with 200-fold selectivity for SR-6 receptors.</p>Fórmula:C18H21Cl2N3O4SPureza:98.94%Cor e Forma:SolidPeso molecular:446.35AVN-492
CAS:<p>AVN-49 is a potent and selective 5-HT6R Antagonist (Ki: 91 pM).</p>Fórmula:C17H21N5O2SPureza:99.81%Cor e Forma:SolidPeso molecular:359.45Azaphen
CAS:<p>Azaphen (Pipofezin hydrochloride) is the reuptake of serotonin inhibitor.with antidepressant action and has sedative effects, suggesting antihistamine activity.</p>Fórmula:C16H21Cl2N5OPureza:97.62%Cor e Forma:SolidPeso molecular:370.28Piboserod
CAS:<p>Piboserod (SB-207266) (SB 207266) is a selective 5-HT(4) receptor antagonist.</p>Fórmula:C22H31N3O2Pureza:97.21% - 99.49%Cor e Forma:SolidPeso molecular:369.5Sarpogrelate
CAS:<p>Sarpogrelate (MCI-9042), an oral 5-HT2 antagonist, boosts platelet aggregation and aids in studying Buerger's disease.</p>Fórmula:C24H31NO6Cor e Forma:SolidPeso molecular:429.51LY334370
CAS:<p>LY334370 is a selective 5-HT1F receptor agonist with a Ki of 1.6 nM</p>Fórmula:C21H22FN3OPureza:99.32%Cor e Forma:SolidPeso molecular:351.42Ansofaxine hydrochloride
CAS:<p>Ansofaxine hydrochloride (LY03005) is a serotonin-norepinephrine-dopamine reuptake inhibitor (IC50s: 723, 763 and 491 nM, respectively).</p>Fórmula:C24H32ClNO3Pureza:99.57% - 99.77%Cor e Forma:SolidPeso molecular:417.97Xaliproden hydrochloride
CAS:<p>Xaliproden is a compound that mimics the effects of nerve growth factor and is also a serotonin 5-HT1A receptor agonist.</p>Fórmula:C24H23ClF3NPureza:99.99%Cor e Forma:SolidPeso molecular:417.89Naluzotan
CAS:<p>Naluzotan（PRX 00023） is a novel and potent 5-HT1A agonist with IC50 and Ki values of approximately 20 nM and 5.1 nM, respectively.Naluzotan is a potent hERG K+</p>Fórmula:C23H38N4O3SPureza:>99.99%Cor e Forma:SolidPeso molecular:450.64Dolasetron
CAS:<p>Dolasetron (MDL-73147)(MDL-73147) is a serotonin 5-HT3 receptor antagonist. Dolasetron is used to treat nausea and vomiting following chemotherapy.</p>Fórmula:C19H20N2O3Pureza:99.84% - 99.86%Cor e Forma:White PowderPeso molecular:324.37AC-90179 HCl
CAS:<p>AC-90179 HCl: selective 5-HT2A inverse agonist, atypical antipsychotic, reduces hallucinogen-induced vasoconstriction.</p>Fórmula:C23H31ClN2O2Pureza:99.71%Cor e Forma:SolidPeso molecular:402.96Ritanserin
CAS:<p>Ritanserin (R 55667) is a long-acting, highly potent, relatively selective, orally bioavailable 5-HT2 receptor antagonist.Cost-effective and quality-assured.</p>Fórmula:C27H25F2N3OSPureza:99.77% - 99.89%Cor e Forma:SolidPeso molecular:477.57Opiranserin hydrochloride
CAS:<p>Opiranserin (VVZ-149) hydrochloride is a dual antagonist of glycine transporter type 2 (GlyT2) and serotonin receptor 2A (5HT2A), with IC50s of 0.86 and 1.3 μM</p>Fórmula:C21H35ClN2O5Pureza:99.33%Cor e Forma:SolidPeso molecular:430.97Eltoprazine dihydrochloride
CAS:<p>Eltoprazine dihydrochloride, a drug developed for aggression, is now studied for L-DOPA-induced dyskinesia in Parkinson's.</p>Fórmula:C12H18Cl2N2O2Pureza:99.64%Cor e Forma:SolidPeso molecular:293.19Almotriptan Malate
CAS:<p>Almotriptan Malate (PNU180638), a selective 5-HT1B/1D receptor agonist, is used in the therapy of Migraine attacks in adults.</p>Fórmula:C17H25N3O2S·C4H6O5Pureza:99.95%Cor e Forma:Pale Yellow SolidPeso molecular:469.55ML 10302
CAS:<p>ML 10302 is a potent 5-HT4 agonist with Ki of 1.07 nM, boosts bowel movement, and may aid in neurology research.</p>Fórmula:C15H21ClN2O3Cor e Forma:SolidPeso molecular:312.79Escitalopram Oxalate
CAS:<p>Escitalopram Oxalate ((S)-(+)Citalopram oxalate) is a selective serotonin (5-HT) reuptake inhibitor (SSRI) with Ki of 0.89 nM.</p>Fórmula:C22H23FN2O5Pureza:97.39% - 99.73%Cor e Forma:White SolidPeso molecular:414.437-Amino-4-(trifluoromethyl)coumarin
CAS:<p>7-Amino-4-(trifluoromethyl)coumarin (Coumarin 151) is a 5-Hydroxytryptamine Receptor Subtype 1E (HTR1E) antagonist.</p>Fórmula:C10H6F3NO2Pureza:97.31% - 97.84%Cor e Forma:Yellow PowderPeso molecular:229.16Nefazodone hydrochloride
CAS:<p>Nefazodone hydrochloride (Serzone) is a serotoninergic modulating antidepressant that is used in therapy of depression, aggressive behavior and panic disorder.</p>Fórmula:C25H33Cl2N5O2Pureza:99% - 99.86%Cor e Forma:White SolidPeso molecular:506.47BRL-15572 dihydrochloride
CAS:<p>BRL-15572 dihydrochloride: 5-HT1D antagonist, pKi 7.9, also binds 5-HT1A/2B, 60x selective over 5-HT1B.</p>Fórmula:C25H27ClN2O·2HClPureza:99.74%Cor e Forma:SolidPeso molecular:479.87Niaprazine
CAS:<p>Niaprazine is a histamine H1-receptor antagonist with marked sedative properties.</p>Fórmula:C20H25FN4OPureza:99.56%Cor e Forma:SolidPeso molecular:356.44Cariprazine
CAS:<p>Cariprazine (RGH-188) is a novel antipsychotic drug candidate that exhibits high affinity for the D3 (Ki=0.085 nM) and D2 (Ki=0.49 nM) receptors, and moderate</p>Fórmula:C21H32Cl2N4OPureza:99.68% - 99.87%Cor e Forma:SolidPeso molecular:427.41Rotigotine Hydrochloride
CAS:<p>Rotigotine HCl, D3-preferential dopamine agonist, is 50x stronger than quinpirole in anti-Parkinson's efficacy.</p>Fórmula:C19H26ClNOSPureza:99.53% - 99.56%Cor e Forma:Almost White To White Crystalline PowderPeso molecular:351.93F-15599
CAS:<p>F-15599 is a highly selective G-protein biased 5-HT1A receptor agonist(Ki : 3.4 nM).</p>Fórmula:C19H21ClF2N4OPureza:98.72%Cor e Forma:SolidPeso molecular:394.85Pirenperone
CAS:<p>Pirenperone is a putative 5-HT2 receptor antagonist with the central antiserotonergic and antidopaminergic action.</p>Fórmula:C23H24FN3O2Pureza:99.2%Cor e Forma:SolidPeso molecular:393.45
