Células - tronco e Derivados

Os inibidores de células-tronco são compostos que visam especificamente as vias de sinalização e proteínas envolvidas na manutenção, diferenciação e proliferação de células-tronco. Esses inibidores são cruciais para compreender a biologia das células-tronco e para desenvolver estratégias para manipular células-tronco para fins terapêuticos, como medicina regenerativa e tratamento do câncer. Ao controlar o destino das células-tronco, esses inibidores podem ajudar a orientar a diferenciação das células-tronco em tipos celulares específicos ou prevenir o crescimento celular indesejado. Na CymitQuimica, oferecemos uma seleção de inibidores de células-tronco de alta qualidade para apoiar sua pesquisa em biologia de células-tronco, biologia do desenvolvimento e medicina regenerativa.

Subcategorias de "Células - tronco e Derivados"

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Foram encontrados 695 produtos de "Células - tronco e Derivados"

Pureza (%)

100

produtos por página.

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Thiazovivin
CAS:
- 1226056-71-8
Thiazovivin, a ROCK inhibitor (IC50: 0.5 μM), increases the survival rate of hESC.
Fórmula:C₁₅H₁₃N₅OS
Pureza:98.00%
Cor e Forma:Solid
Peso molecular:311.36
Ref: TM-T2155
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Afuresertib hydrochloride
CAS:
- 1047645-82-8
Afuresertib hydrochloride is an inhibitor of Akt kinase (Kis of 0.08/2/2.6 nM for Akt1/Akt2/Akt3 respectively)
Fórmula:C₁₈H₁₈Cl₃FN₄OS
Pureza:99.96%
Cor e Forma:Solid
Peso molecular:463.8
Ref: TM-T7885
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BP-1-102
CAS:
- 1334493-07-0
BP-1-102 is an orally active, effective and specific STAT3 inhibitor.
Fórmula:C₂₉H₂₇F₅N₂O₆S
Pureza:99.25% - 99.44%
Cor e Forma:Solid
Peso molecular:626.59
Ref: TM-T3708
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Belumosudil
CAS:
- 911417-87-3
Belumosudil (Rezurock) is an orally available, and specific ROCK2 inhibitor (IC50/Ki: 60/41 nM).
Fórmula:C₂₆H₂₄N₆O₂
Pureza:97.64% - 98.59%
Cor e Forma:Solid
Peso molecular:452.51
Ref: TM-T6867
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iCRT 14
CAS:
- 677331-12-3
iCRT 14 is a novel potent inhibitor of β-catenin-responsive transcription (CRT)(IC50= 40.3 nM in assays of Wnt pathway activity).
Fórmula:C₂₁H₁₇N₃O₂S
Pureza:99.8% - 99.97%
Cor e Forma:Solid
Peso molecular:375.44
Ref: TM-T4486
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Cucurbitacin I
CAS:
- 2222-07-3
Cucurbitacin I (JSI-124), a natural compound, is a selective inhibitor of JAK2/STAT3 with anti-cancer activity.
Fórmula:C₃₀H₄₂O₇
Pureza:96.69% - 99.8%
Cor e Forma:Solid
Peso molecular:514.65
Ref: TM-TQ0196
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CMD178 TFA
CMD178 (TFA) is a lead peptide that consistently reduces the expression of Foxp3 and STAT5 induced by IL-2/s IL-2Rα signaling.
Fórmula:C₄₈H₆₀F₃N₉O₉
Pureza:>99.99%
Cor e Forma:Solid
Peso molecular:964.05
Ref: TM-TP1433
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URMC-099
CAS:
- 1229582-33-5
URMC-099: oral, brain-accessible MLK/LRRK2 inhibitor; IC50 – MLK1/2/3/DLK: 19/42/14/150 nM, LRRK2: 11 nM.
Fórmula:C₂₇H₂₇N₅
Pureza:99.32% - 99.98%
Cor e Forma:Solid
Peso molecular:421.54
Ref: TM-T6057
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β-catenin-IN-2
CAS:
- 1458664-10-2
β-catenin-IN-2 is a potent inhibitor of β-catenin that can be used in colorectal cancer research.
Fórmula:C₁₅H₁₄FN₃
Pureza:99.93%
Cor e Forma:Solid
Peso molecular:255.29
Ref: TM-T9696
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Teplinovivint
CAS:
- 1428064-91-8
Teplinovivint is a potent inhibitor of the Wnt/β-catenin signaling pathway, demonstrating anti-inflammatory properties with potential utility in tendinopathy
Fórmula:C₂₅H₂₆N₆O₂
Pureza:97.21%
Cor e Forma:Solid
Peso molecular:442.51
Ref: TM-T9151
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WHI-P154
CAS:
- 211555-04-3
WHI-P154 (Jak3 inhibitor ii) is a potent JAK3 inhibitor.
Fórmula:C₁₆H₁₄BrN₃O₃
Pureza:98% - 99.67%
Cor e Forma:Solid
Peso molecular:376.2
Ref: TM-T1985
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XMU-MP-1
CAS:
- 2061980-01-4
XMU-MP-1 is a reversible and selective MST1/2 kinase inhibitor, IC50 values for MST1 and MST2 are 71.1 nM and 38.1 nM, respectively. High-Quality, Low-Cost!
Fórmula:C₁₇H₁₆N₆O₃S₂
Pureza:99.68% - 99.79%
Cor e Forma:Solid
Peso molecular:416.48
Ref: TM-T4212
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BMS-911543
CAS:
- 1271022-90-2
BMS-911543 is a potent and selective inhibitor of JAK2 with IC50 of 1.1 nM, ~350-, 75- and 65-fold selective to JAK1, JAK3 and TYK2, respectively. Phase 1/2.
Fórmula:C₂₃H₂₈N₈O
Pureza:97.69% - 99.98%
Cor e Forma:Solid
Peso molecular:432.52
Ref: TM-T6790
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Avagacestat
CAS:
- 1146699-66-2
Avagacestat (BMS-708163) (BMS-708163) is a potent, selective, orally bioavailable γ-secretase inhibitor of Aβ40 and Aβ42 with IC50 of 0.3 nM and 0.27 nM,
Fórmula:C₂₀H₁₇ClF₄N₄O₄S
Pureza:98.87% - 99.73%
Cor e Forma:Solid
Peso molecular:520.89
Ref: TM-T6249
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SAR407899 hydrochloride
CAS:
- 923262-96-8
SAR407899 hydrochloride is a selective, potent and ATP-competitive ROCK inhibitor, with an IC50 of 135 nM for ROCK-2, and Kis of 36 nM and 41 nM for human and
Fórmula:C₁₄H₁₇ClN₂O₂
Pureza:99.15%
Cor e Forma:Solid
Peso molecular:280.75
Ref: TM-T23308
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Cardiogenol C
CAS:
- 671225-39-1
Cardiogenol C is a cardiomyogenesis inducer in embryonic stem cells.
Fórmula:C₁₃H₁₆N₄O₂
Pureza:98.46%
Cor e Forma:Solid
Peso molecular:260.29
Ref: TM-T2161
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Upadacitinib
CAS:
- 1310726-60-3
Upadacitinib (ABT-494), a selective JAK1 inhibitor, is researched for autoimmune diseases; IC50: 43 nM.
Fórmula:C₁₇H₁₉F₃N₆O
Pureza:98.96% - 99.94%
Cor e Forma:Solid
Peso molecular:380.37
Ref: TM-T7503
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AZD1080
CAS:
- 612487-72-6
AZD1080 is a selective, orally active, brain permeable GSK3 inhibitor.
Fórmula:C₁₉H₁₈N₄O₂
Pureza:97.72% - 99.75%
Cor e Forma:Solid
Peso molecular:334.37
Ref: TM-T1741
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IMR-1A
CAS:
- 331862-41-0
IMR-1A is the metabolite of IMR-1 which is a novel class of Notch inhibitors targeting the transcriptional activation with IC50 of 6 μMol/L.
Fórmula:C₁₃H₁₁NO₅S₂
Pureza:97.1% - 99.76%
Cor e Forma:Solid
Peso molecular:325.36
Ref: TM-T3540
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IHR-1
CAS:
- 548779-60-8
IHR-1, a Smo inhibitor (IC50 7.6 nM), blocks Hedgehog pathway, not Wnt/Notch, and prevents Smo in primary cilium.
Fórmula:C₂₀H₁₂Cl₄N₂O₂
Pureza:97.02%
Cor e Forma:Solid
Peso molecular:454.13
Ref: TM-T24159