Células - tronco e Derivados

Os inibidores de células-tronco são compostos que visam especificamente as vias de sinalização e proteínas envolvidas na manutenção, diferenciação e proliferação de células-tronco. Esses inibidores são cruciais para compreender a biologia das células-tronco e para desenvolver estratégias para manipular células-tronco para fins terapêuticos, como medicina regenerativa e tratamento do câncer. Ao controlar o destino das células-tronco, esses inibidores podem ajudar a orientar a diferenciação das células-tronco em tipos celulares específicos ou prevenir o crescimento celular indesejado. Na CymitQuimica, oferecemos uma seleção de inibidores de células-tronco de alta qualidade para apoiar sua pesquisa em biologia de células-tronco, biologia do desenvolvimento e medicina regenerativa.

Subcategorias de "Células - tronco e Derivados"

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Foram encontrados 695 produtos de "Células - tronco e Derivados"

Pureza (%)

100

produtos por página.

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TTP 22
CAS:
- 329907-28-0
TTP 22: ATP-competitive CK2 inhibitor; IC50/Ki: 0.1 μM/40 nM; >250x selective over JNK3, ROCK1, MET.
Fórmula:C₁₆H₁₄N₂O₂S₂
Pureza:97.08% - 97.78%
Cor e Forma:Solid
Peso molecular:330.42
Ref: TM-T1828
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SH-4-54
CAS:
- 1456632-40-8
SH-4-54 is a most potent, small molecule, nonphosphorylated STAT3 inhibitor.
Fórmula:C₂₉H₂₇F₅N₂O₅S
Pureza:98% - 99.12%
Cor e Forma:Solid
Peso molecular:610.59
Ref: TM-T6669
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TDZD-8
CAS:
- 327036-89-5
TDZD-8 (NP 01139) is an inhibitor of GSK-3β, with an IC50 of 2 μM; minimal inhibitory effect observed on CDK1, casein kinase II, PKA and PKC.
Fórmula:C₁₀H₁₀N₂O₂S
Pureza:97.13% - 99.61%
Cor e Forma:White Solid
Peso molecular:222.26
Ref: TM-T6187
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JI130
CAS:
- 2234271-86-2
JI130 hinders Hes1 transcription repression; notably shrinks pancreatic tumor volume in mice.
Fórmula:C₂₃H₂₄N₂O₃
Pureza:99.61%
Cor e Forma:Solid
Peso molecular:376.45
Ref: TM-T9588
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GS87
CAS:
- 919936-70-2
GS87 is a highly specific inhibitor of GSK3 (glycogen synthase kinase 3) that induces extensive differentiation of AML cells.
Fórmula:C₁₆H₁₁N₅O₂S
Pureza:98.86%
Cor e Forma:Solid
Peso molecular:337.36
Ref: TM-T8605
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Tegatrabetan
CAS:
- 1227637-23-1
Tegatrabetan (BC2059) is a small molecule inhibitor of the Wnt/beta-catenin pathway with potential antineoplastic activity.
Fórmula:C₂₈H₃₆N₄O₆S₂
Pureza:98.01% - 99.18%
Cor e Forma:Solid
Peso molecular:588.74
Ref: TM-T5642
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Baricitinib
CAS:
- 1187594-09-7
Baricitinib (INCB028050) is an orally JAK1 and JAK2 inhibitor. Baricitinib has anti-inflammatory and anti-tumor activity. Cost-effective and quality-assured.
Fórmula:C₁₆H₁₇N₇O₂S
Pureza:99% - >99.99%
Cor e Forma:Solid
Peso molecular:371.42
Ref: TM-T2485
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Hydroxyfasudil
CAS:
- 105628-72-6
Hydroxyfasudil (Hydroxy-Fasudil) is a ROCK inhibitor(IC50s of 0.73 and 0.72 μM for ROCK1 and ROCK2, respectively).
Fórmula:C₁₄H₁₇N₃O₃S
Pureza:98.13%
Cor e Forma:Solid
Peso molecular:307.37
Ref: TM-T4276L
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Porcn-IN-1
CAS:
- 2036044-77-4
Porcn-IN-1 (Porcupine-IN-1) is an effective porcupine inhibitor (IC50: 0.5±0.2 nM).
Fórmula:C₂₅H₁₉FN₄O
Pureza:99.15%
Cor e Forma:Solid
Peso molecular:410.44
Ref: TM-T4438
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Thiazovivin
CAS:
- 1226056-71-8
Thiazovivin, a ROCK inhibitor (IC50: 0.5 μM), increases the survival rate of hESC.
Fórmula:C₁₅H₁₃N₅OS
Pureza:98.00%
Cor e Forma:Solid
Peso molecular:311.36
Ref: TM-T2155
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GDC-0214
CAS:
- 1831144-46-7
GDC-0214 is an inhaled small-molecule JAK1 inhibitor and reduces fractional exhaled nitric oxide (Feno).
Fórmula:C₂₈H₂₈ClF₂N₉O₃
Pureza:99.75%
Cor e Forma:Solid
Peso molecular:612.03
Ref: TM-T9826
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IWP-O1
CAS:
- 2074607-48-8
IWP-O1 is a highly potent Porcupine (Porcn) inhibitor (EC50: 80 pM), effectively suppresses the phosphorylation of Dvl2/3 and LRP6 in HeLa cells.
Fórmula:C₂₆H₂₀N₆O
Pureza:99.12%
Cor e Forma:Solid
Peso molecular:432.48
Ref: TM-T5342
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2,6-Dichloro-N-(2-(cyclopropanecarboxamido)pyridin-4-yl)benzamide
CAS:
- 1258292-64-6
2,6-Dichloro-N-(2-(cyclopropanecarboxamido)pyridin-4-yl)benzamide (GDC046), a potent lead analog, has good kinase selectivity and physicochemical properties.
Fórmula:C₁₆H₁₃Cl₂N₃O₂
Pureza:98.77%
Cor e Forma:Solid
Peso molecular:350.2
Ref: TM-T22338
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(E/Z)-GO289
CAS:
- 694522-87-7
(E/Z)-GO289, which strongly lengthened circadian period, is a potent and selective inhibitor of CK2.
Fórmula:C₁₇H₁₅BrN₄O₂S
Pureza:98.1%
Cor e Forma:Solid
Peso molecular:419.3
Ref: TM-T9356
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BIO-013077-01
CAS:
- 746667-48-1
BIO-013077-01 is a potent TGFbeta family type I receptors antagonist.
Fórmula:C₁₇H₁₃N₅
Pureza:99.87%
Cor e Forma:Solid
Peso molecular:287.32
Ref: TM-T8330
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AS-252424
CAS:
- 900515-16-4
AS-252424 is a potent and selective inhibitor of PI3Kγ with IC50 of 33 nM; >10 fold selectivity for PI3Kγ versus PI3Kα.
Fórmula:C₁₄H₈FNO₄S
Pureza:99.06% - 99.09%
Cor e Forma:Solid
Peso molecular:305.28
Ref: TM-T6208
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Filgotinib
CAS:
- 1206161-97-8
Filgotinib (GLPG0634) is a selective JAK1 inhibitor. The IC50 values against JAK1, JAK2, JAK3, and TYK2 are 10 nM, 28 nM, 810 nM, and 116 nM, respectively.
Fórmula:C₂₁H₂₃N₅O₃S
Pureza:98.03% - ≥95%
Cor e Forma:Solid
Peso molecular:425.5
Ref: TM-T1929
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Upadacitinib
CAS:
- 1310726-60-3
Upadacitinib (ABT-494), a selective JAK1 inhibitor, is researched for autoimmune diseases; IC50: 43 nM.
Fórmula:C₁₇H₁₉F₃N₆O
Pureza:98.96% - 99.94%
Cor e Forma:Solid
Peso molecular:380.37
Ref: TM-T7503
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KenPaullone
CAS:
- 142273-20-9
KenPaullone (9-Bromopaullone), a potent CDK1, CDK2 and CDK5 inhibitor, as new enhancer for iTreg cell differentiation.
Fórmula:C₁₆H₁₁BrN₂O
Pureza:97.14% - 98.99%
Cor e Forma:Tan Solid
Peso molecular:327.18
Ref: TM-T2247
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Crenigacestat
CAS:
- 1421438-81-4
Crenigacestat (LY3039478) is an orally bioavailable Notch inhibitor with an IC50 of ~1 nM in most of the tumor cell lines tested.
Fórmula:C₂₂H₂₃F₃N₄O₄
Pureza:97.27% - 98.99%
Cor e Forma:Solid
Peso molecular:464.44
Ref: TM-T3633