Células - tronco e Derivados

Os inibidores de células-tronco são compostos que visam especificamente as vias de sinalização e proteínas envolvidas na manutenção, diferenciação e proliferação de células-tronco. Esses inibidores são cruciais para compreender a biologia das células-tronco e para desenvolver estratégias para manipular células-tronco para fins terapêuticos, como medicina regenerativa e tratamento do câncer. Ao controlar o destino das células-tronco, esses inibidores podem ajudar a orientar a diferenciação das células-tronco em tipos celulares específicos ou prevenir o crescimento celular indesejado. Na CymitQuimica, oferecemos uma seleção de inibidores de células-tronco de alta qualidade para apoiar sua pesquisa em biologia de células-tronco, biologia do desenvolvimento e medicina regenerativa.

Subcategorias de "Células - tronco e Derivados"

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Foram encontrados 695 produtos de "Células - tronco e Derivados"

Pureza (%)

100

produtos por página.

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Pacritinib hydrochloride
CAS:
- 1228923-43-0
Pacritinib HCl: strong JAK2/Wild-type & JAK2V617F inhibitor (IC50: 23/19 nM), used in AML & MF research.
Fórmula:C₂₈H₃₂N₄O₃·xClH
Cor e Forma:Solid
Ref: TM-T64283
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(E)-SIS3
CAS:
- 521984-48-5
(E)-SIS3 (SIS3) is a Smad3 inhibitor (IC50=3 μM) selective.inhibits the differentiation of fibroblasts into myofibroblasts via TGF-β1. High-Quality, Low-Cost!
Fórmula:C₂₈H₂₇N₃O₃·HCl
Pureza:95.64% - 98%
Cor e Forma:Solid
Peso molecular:489.99
Ref: TM-T3636
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AZD2858
CAS:
- 486424-20-8
AZD2858 is a selective GSK-3 inhibitor, inhibiting tau phosphorylation at the S396 site and activating Wnt signaling pathway.
Fórmula:C₂₁H₂₃N₇O₃S
Pureza:98% - 99.25%
Cor e Forma:Solid
Peso molecular:453.52
Ref: TM-T1957
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Wnt-C59
CAS:
- 1243243-89-1
Wnt-C59 (C59)(C59) is a highly effective and specific Wnt signaling antagonis with PORCN enzymatic activity.
Fórmula:C₂₅H₂₁N₃O
Pureza:99.56% - 99.95%
Cor e Forma:Solid
Peso molecular:379.45
Ref: TM-T2242
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SAR407899
CAS:
- 923359-38-0
SAR407899 is Rho kinase inhibitor potently inhibits endothelin-1-induced constriction of renal resistance arteries.
Fórmula:C₁₄H₁₆N₂O₂
Pureza:99.42%
Cor e Forma:Solid
Peso molecular:244.29
Ref: TM-T7391
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SRI-011381 hydrochloride
CAS:
- 2070014-88-7
SRI-011381 hydrochloride, a new-type agonist of the TGF-beta signaling pathway, is utilized in the treatment of Alzheimer's disease.
Fórmula:C₂₀H₃₂ClN₃O
Pureza:99.32% - 99.41%
Cor e Forma:Solid
Peso molecular:365.94
Ref: TM-T5129
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FLLL32
CAS:
- 1226895-15-3
FLLL32 is an effective JAK2/STAT3 inhibitor (IC50 of <5 μM).
Fórmula:C₂₈H₃₂O₆
Pureza:97% - 97.90%
Cor e Forma:Solid
Peso molecular:464.55
Ref: TM-T6838
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Gusacitinib HCl
CAS:
- 2228989-14-6
Gusacitinib (ASN-002/EN-3351), a potent SYK/JAK inhibitor, has strong antitumor activity in various cancers.
Fórmula:C₂₄H₂₉ClN₈O₂
Cor e Forma:Solid
Peso molecular:497
Ref: TM-T69766
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SR-3029
CAS:
- 1454585-06-8
SR-3029 is a potent and highly specific CK1δ/CK1ε inhibitor.
Fórmula:C₂₃H₁₉F₃N₈O
Pureza:99.64%
Cor e Forma:Solid
Peso molecular:480.45
Ref: TM-T3972
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MRT-14
CAS:
- 1263131-83-4
MRT-14 is a potent Smo antagonist and can be used in several types of cancers linked to abnormal Hh signaling studies.
Fórmula:C₂₄H₂₄N₄O₅
Pureza:99.54%
Cor e Forma:Solid
Peso molecular:448.47
Ref: TM-T9531
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RO495
CAS:
- 1258296-60-4
RO495 (CS-2667), a potent inhibitor of TYK2, inhibits TYK2 with IC50 of 1.5nM as tested in cell-based pharmacological assays
Fórmula:C₁₇H₁₄Cl₂N₆O
Pureza:97.94%
Cor e Forma:Solid
Peso molecular:389.24
Ref: TM-T22416
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(E/Z)-Zotiraciclib
CAS:
- 937270-47-8
(E/Z)-Zotiraciclib ((E/Z)-TG02) inhibits CDK2, JAK2, and FLT3 effectively with IC50s of 13, 73, and 56 nM, respectively.
Fórmula:C₂₃H₂₄N₄O
Pureza:97.75% - 99.92%
Cor e Forma:Solid
Peso molecular:372.46
Ref: TM-T21503
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ROCK-IN-2
CAS:
- 867017-68-3
ROCK-IN-2 (Azaindole 1) is a selective and ATP-competitive ROCK inhibitor with IC50 of 0.6 and 1.1 nM for human ROCK-1 and ROCK-2.
Fórmula:C₁₈H₁₃ClF₂N₆O
Pureza:97.29%
Cor e Forma:Solid
Peso molecular:402.79
Ref: TM-TQ0110
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Fz7-21
CAS:
- 2247635-23-8
Fz7-21, a peptide antagonist of FZD7, inhibits Wnt/β-catenin signaling (IC50=50-100nM) in cells with WNT3A.
Fórmula:C₈₃H₁₁₄N₁₈O₂₃S₂
Pureza:99.8%
Cor e Forma:Solid
Peso molecular:1796.03
Ref: TM-TP1263
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G5-7
CAS:
- 939681-36-4
G5-7 is an oral JAK2 inhibitor targeting EGFR/STAT3 phosphorylation with potential for glioma research.
Fórmula:C₂₂H₁₉F₂NO₃
Pureza:97.3%
Cor e Forma:Solid
Peso molecular:383.39
Ref: TM-T8742
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Decernotinib
CAS:
- 944842-54-0
Decernotinib (VRT-831509)(VX-509; VRT-831509) is a potent and selective Janus kinase 3 (JAK3) inhibitor with Ki of 2.5 nM; IC50 is 50-170 nM in cellular assays.
Fórmula:C₁₈H₁₉F₃N₆O
Pureza:99.28% - >99.99%
Cor e Forma:Solid
Peso molecular:392.38
Ref: TM-T2636
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γ-secretase modulator 1 hydrochloride
CAS:
- 2741571-83-3
gamma-secretase inhibitior-1 is a gamma-secretase modulator that is useful to Alzheimer's disease [1].
Fórmula:C₂₄H₂₅ClN₄OS
Pureza:98%
Cor e Forma:Solid
Peso molecular:453
Ref: TM-T11358L
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Gandotinib
CAS:
- 1229236-86-5
LY2784544(Gandotinib (LY2784544)) is a potent JAK2 inhibitor (IC50: 3 nM), effective in JAK2V617F(Ki: 0.245 nM).
Fórmula:C₂₃H₂₅ClFN₇O
Pureza:99.33% - 99.86%
Cor e Forma:Solid
Peso molecular:469.94
Ref: TM-T2638
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Wnt pathway activator 1
CAS:
- 1360540-81-3
Wnt pathway activator 1 is a potent Wnt activator with an IC50 of 28-29 nM.
Fórmula:C₁₈H₁₆O₄
Pureza:99.93%
Cor e Forma:Solid
Peso molecular:296.32
Ref: TM-T17256
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AMG-47a
CAS:
- 882663-88-9
AMG-47a inhibits Lck, T cell growth, and degrades KRAS oncoprotein, affecting EGFP-KRASG12V but not EGFP.
Fórmula:C₂₉H₂₈F₃N₅O₂
Pureza:98%
Cor e Forma:Solid
Peso molecular:535.56
Ref: TM-T7123