Células - tronco e Derivados

Os inibidores de células-tronco são compostos que visam especificamente as vias de sinalização e proteínas envolvidas na manutenção, diferenciação e proliferação de células-tronco. Esses inibidores são cruciais para compreender a biologia das células-tronco e para desenvolver estratégias para manipular células-tronco para fins terapêuticos, como medicina regenerativa e tratamento do câncer. Ao controlar o destino das células-tronco, esses inibidores podem ajudar a orientar a diferenciação das células-tronco em tipos celulares específicos ou prevenir o crescimento celular indesejado. Na CymitQuimica, oferecemos uma seleção de inibidores de células-tronco de alta qualidade para apoiar sua pesquisa em biologia de células-tronco, biologia do desenvolvimento e medicina regenerativa.

Subcategorias de "Células - tronco e Derivados"

Exibir 2 mais subcategorias

Foram encontrados 695 produtos de "Células - tronco e Derivados"

Pureza (%)

100

produtos por página.

+ Info
RO8191
CAS:
- 691868-88-9
RO8191 (CDM-3008) (CDM-3008) is an agonist of interferon (IFN) receptor.
Fórmula:C₁₄H₅F₆N₅O
Pureza:98% - 98.85%
Cor e Forma:Solid
Peso molecular:373.21
Ref: TM-T22142
+ Info
SH5-07
CAS:
- 1456632-41-9
SH5-07 is a hydroxamic acid-based Stat3 inhibitor (IC50: 3.9 μM).
Fórmula:C₂₉H₂₈F₅N₃O₅S
Pureza:95.54%
Cor e Forma:Solid
Peso molecular:625.61
Ref: TM-TQ0052
+ Info
Tofacitinib
CAS:
- 477600-75-2
Tofacitinib (Tasocitinib) is an orally Janus kinase inhibitor. Tofacitinib is used for the treatment of rheumatoid arthritis. Cost effective and quality assured.
Fórmula:C₁₆H₂₀N₆O
Pureza:99% - >99.99%
Cor e Forma:Solid
Peso molecular:312.37
Ref: TM-T6321
+ Info
Ruxolitinib (S enantiomer)
CAS:
- 941685-37-6
Ruxolitinib S enantiomer (INCB18424) is the S-enantiomer of Ruxolitinib. Ruxolitinib is the first potent, selective JAK1/2 inhibitor.
Fórmula:C₁₇H₁₈N₆
Pureza:99.37% - 99.79%
Cor e Forma:Solid
Peso molecular:306.36
Ref: TM-T6156
+ Info
BMP signaling agonist sb4
CAS:
- 100874-08-6
BMP signaling agonist sb4 (SB 4) is an agonist of benzoxazole bone morphogenetic protein (BMP) signaling (EC50 :74 nM)
Fórmula:C₁₄H₁₀BrNOS
Pureza:99.48% - 99.805%
Cor e Forma:Solid
Peso molecular:320.2
Ref: TM-T7799
+ Info
2,6-Dichloro-N-(2-(cyclopropanecarboxamido)pyridin-4-yl)benzamide
CAS:
- 1258292-64-6
2,6-Dichloro-N-(2-(cyclopropanecarboxamido)pyridin-4-yl)benzamide (GDC046), a potent lead analog, has good kinase selectivity and physicochemical properties.
Fórmula:C₁₆H₁₃Cl₂N₃O₂
Pureza:98.77%
Cor e Forma:Solid
Peso molecular:350.2
Ref: TM-T22338
+ Info
IMR-1
CAS:
- 310456-65-6
IMR-1 is a novel class of Notch inhibitors targeting the transcriptional activation with IC50 of 6 μMol/L.
Fórmula:C₁₅H₁₅NO₅S₂
Pureza:97.96% - 98.38%
Cor e Forma:Solid
Peso molecular:353.41
Ref: TM-T6861
+ Info
Pacritinib hydrochloride
CAS:
- 1228923-43-0
Pacritinib HCl: strong JAK2/Wild-type & JAK2V617F inhibitor (IC50: 23/19 nM), used in AML & MF research.
Fórmula:C₂₈H₃₂N₄O₃·xClH
Cor e Forma:Solid
Ref: TM-T64283
+ Info
PF-670462
CAS:
- 950912-80-8
PF-670462 is a potent (IC50 = 7.7 ± 2.2 nM) and selective (>30-fold with respect to 42 additional kinases) inhibitor of CK1ε in isolated enzyme preparations.
Fórmula:C₁₉H₂₂Cl₂FN₅
Pureza:99.42% - 99.72%
Cor e Forma:Solid
Peso molecular:410.32
Ref: TM-T3073
+ Info
FH535
CAS:
- 108409-83-2
FH535, a Wnt/β-catenin signaling and PPAR inhibitor, exhibits anti-tumor activities.
Fórmula:C₁₃H₁₀Cl₂N₂O₄S
Pureza:98.25% - 99.5%
Cor e Forma:Solid
Peso molecular:361.2
Ref: TM-T2413
+ Info
KY02111
CAS:
- 1118807-13-8
KY02111 facilitates differentiation of hPSCs to cardiomyocytes by inhibiting Wnt signaling, maybe affect downstream of GSK3β and APC.
Fórmula:C₁₈H₁₇ClN₂O₃S
Pureza:97.71% - 98.3%
Cor e Forma:Solid
Peso molecular:376.86
Ref: TM-T2052
+ Info
Cardiogenol C hydrochloride
CAS:
- 1049741-55-0
Cardiogenol C hydrochloride (Cardiogenol C) can induces the differentiation of ESCs into cardiomyocytes (EC50= 100 nM).
Fórmula:C₁₃H₁₇ClN₄O₂
Pureza:99.89% - 99.94%
Cor e Forma:Solid
Peso molecular:296.75
Ref: TM-T8005
+ Info
KY19382
CAS:
- 2226664-93-1
KY19382, a dual CXXC5-DVL and GSK3β inhibitor (IC50s: 19/10 nM), boosts Wnt/β-catenin signaling and may help in metabolic disease research.
Fórmula:C₁₇H₁₁Cl₂N₃O₂
Pureza:98.06%
Cor e Forma:Solid
Peso molecular:360.19
Ref: TM-T9025
+ Info
RKI-1447
CAS:
- 1342278-01-6
RKI-1447 is a potent inhibitor of ROCK1 and ROCK2. It has anti-invasive and antitumor activities.
Fórmula:C₁₆H₁₄N₄O₂S
Pureza:98% - 99.73%
Cor e Forma:Solid
Peso molecular:326.37
Ref: TM-T1898
+ Info
Wnt pathway activator 1
CAS:
- 1360540-81-3
Wnt pathway activator 1 is a potent Wnt activator with an IC50 of 28-29 nM.
Fórmula:C₁₈H₁₆O₄
Pureza:99.93%
Cor e Forma:Solid
Peso molecular:296.32
Ref: TM-T17256
+ Info
Pyrvinium pamoate
CAS:
- 3546-41-6
Pyrvinium pamoate (Pyrvinium embonate) is an old anthelminthic medicine for the treatment of enterobiasis , which re-attracts attention as an anti-cancer drug
Fórmula:C₂₆H₂₈N₃C₂₃H₁₄O₆
Pureza:99.76% - >99.99%
Cor e Forma:Solid
Peso molecular:575.71
Ref: TM-T7333
+ Info
AG490
CAS:
- 133550-30-8
AG490 inhibits EGFR (0.1 μM IC50), 135x > selective than ErbB2, blocks JAK2, spares Lyn, Lck, Syk, Btk, Src.
Fórmula:C₁₇H₁₄N₂O₃
Pureza:98.6% - 99.39%
Cor e Forma:Yellow Solid
Peso molecular:294.3
Ref: TM-T2600
+ Info
Ritlecitinib
CAS:
- 1792180-81-4
Ritlecitinib (PF-06651600) is an orally available, selective JAK3 inhibitor and does not affect the activity of JAK1/2.Cost-effective and quality-assured.
Fórmula:C₁₅H₁₉N₅O
Pureza:98.82% - 99.92%
Cor e Forma:Solid
Peso molecular:285.34
Ref: TM-T5382
+ Info
SAR-20347
CAS:
- 1450881-55-6
SAR-20347 is an inhibitor of TYK2, JAK1/2/3 (IC50: 0.6/23/26/41 nM).
Fórmula:C₂₁H₁₈ClFN₄O₄
Pureza:98.99% - 99.77%
Cor e Forma:Solid
Peso molecular:444.84
Ref: TM-T4210
+ Info
BD750
CAS:
- 892686-59-8
BD750 is an effective immunosuppressant and a JAK3/STAT5 inhibitor, inhibits IL-2-induced JAK3/STAT5-dependent T cell proliferation(IC50 of 1.5 μM and 1.1 μM in
Fórmula:C₁₄H₁₃N₃OS
Pureza:99.02%
Cor e Forma:Solid
Peso molecular:271.34
Ref: TM-T8546