Células - tronco
Os inibidores de células-tronco são compostos que atuam especificamente nas células-tronco e em suas vias de sinalização, afetando sua capacidade de autorrenovação e diferenciação. Esses inibidores são cruciais em pesquisas focadas no controle do comportamento das células-tronco, na compreensão dos processos de desenvolvimento e no desenvolvimento de terapias para doenças como o câncer, onde se acredita que as células-tronco desempenhem um papel fundamental. Na CymitQuimica, oferecemos uma variedade de inibidores de células-tronco para apoiar sua pesquisa em medicina regenerativa, biologia do desenvolvimento e oncologia.
Foram encontrados 485 produtos de "Células - tronco"
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BRD5648
CAS:<p>BRD5648 ((R)-BRD0705) is an inactive (R)-enantiomer of BRD0705.</p>Fórmula:C20H23N3OPureza:99.89%Cor e Forma:SolidPeso molecular:321.42ROCK-IN-7
CAS:<p>ROCK-IN-7 (compound 9) serves as a ROCK kinase inhibitor and is utilized in the investigation of ocular conditions, including glaucoma and retinal diseases [1].</p>Fórmula:C17H17N3O2SPureza:98%Cor e Forma:SolidPeso molecular:327.4Chroman 1
CAS:<p>Chroman 1 is a potent inhibitor of ROCK1 (IC50 = 52 pM) and ROCK2 (IC50 = 1 pM).</p>Fórmula:C24H28N4O4Pureza:99.67% - 99.84%Cor e Forma:SolidPeso molecular:436.5ROCK2-IN-6 hydrochloride
CAS:<p>ROCK2-IN-6 hydrochloride (Comp A)为一种选择性ROCK2抑制剂，适用于研究ROCK介导的疾病、自身免疫性病症与炎症。</p>Fórmula:C26H22ClF2N7OPureza:98%Cor e Forma:SolidPeso molecular:521.95TGFβ-IN-5
CAS:<p>TGFβ-IN-5 (WAY-641966) is a potent TGFβ inhibitor with anti-prion activity for the study of fibroproliferative diseases associated with TGF-β signaling.</p>Fórmula:C20H16N4Pureza:99.29% - 99.5%Cor e Forma:SolidPeso molecular:312.37TCS 21311
CAS:<p>TCS 21311 (NIBR3049) selectively inhibits JAK3 (IC50: 8 nM) and PKCα/θ & GSK3β; >100x selective over JAK1, JAK2, TYK2.</p>Fórmula:C27H25F3N4O4Pureza:99.39% - ≥98%Cor e Forma:SolidPeso molecular:526.51Casein kinase 1δ-IN-5
CAS:<p>Casein kinase 1δ-IN-5 is a potent and selective CK-1δ inhibitor, exhibiting an IC50 of 47 nM, and demonstrates neuroprotective and anti-inflammatory effects in</p>Fórmula:C16H11F3N2OSPureza:98%Cor e Forma:SolidPeso molecular:336.33MRK-560
CAS:<p>MRK-560 is an effective and brain-penetrant inhibitor of γ-secretase.</p>Fórmula:C19H17ClF5NO4S2Pureza:98.87%Cor e Forma:SolidPeso molecular:517.92TP0427736
CAS:<p>TP0427736: ALK5 inhibitor, IC50=2.72 nM, 300x > ALK3 selectivity; counters TGF-β in human cells, extends anagen in mice.</p>Fórmula:C14H10N4S2Pureza:97.26%Cor e Forma:SolidPeso molecular:298.39STAT3-IN-B9
CAS:<p>STAT3-IN-B9 (B9) is an inhibitor of abnormal STAT3 activation and inhibits the proliferation of tumor cells including MDA-MB-468, MDA-MB-231, and DU145.</p>Fórmula:C20H13NO5SPureza:98.19%Cor e Forma:SolidPeso molecular:379.39ML115
CAS:<p>ML115 is a potent and selective activator of transcription 3 (STAT3), with abn EC50 of 2.0 nM, and is inactive against the related STAT1 and NFκB anti-targets.</p>Fórmula:C15H15ClN2O4Pureza:99.97%Cor e Forma:SolidPeso molecular:322.74LX7101
CAS:<p>LX7101 is an effective inhibitor of LIMK and ROCK2 (IC50: 24, 1.6, and 10 nM for LIMK1, LIMK2, and ROCK2, respectively). It also inhibits PKA (IC50 <1 nM).</p>Fórmula:C23H29N7O3Pureza:99.08%Cor e Forma:SolidPeso molecular:451.52BMS-983970
CAS:<p>BMS-983970 is an oral inhibitor of pan-Notch, and for the treatment of multiplecancers.</p>Fórmula:C26H26F4N4O3Cor e Forma:SolidPeso molecular:518.5Stafib-2
CAS:<p>Stafib-2 is a potent and selective inhibitor of the transcription factor STAT5b.Stafib-2 inhibits STAT5b and STAT5a with IC50 values of 82 nM and 1.7 μM,</p>Fórmula:C28H26N2O12P2Pureza:98.48%Cor e Forma:SolidPeso molecular:644.46A 1070722
CAS:<p>A 1070722: potent GSK-3 inhibitor, Ki = 0.6 nM for both α/β isoforms, crosses BBB, potential brain GSK-3 PET radiotracer.</p>Fórmula:C17H13F3N4O2Pureza:99.9%Cor e Forma:SolidPeso molecular:362.31ROCK2-IN-2
CAS:<p>ROCK2-IN-2 is a selective inhibitor of ROCK2 (IC50 of <1 μM).</p>Fórmula:C18H12N6OSPureza:99.65%Cor e Forma:SolidPeso molecular:360.39JW 67
CAS:<p>JW 67 is an inhibitor of canonical Wnt pathway signaling.</p>Fórmula:C21H18N2O6Pureza:99.02%Cor e Forma:SolidPeso molecular:394.38JAK-IN-5
CAS:<p>JAK-IN-5 is a JAK inhibitor.</p>Fórmula:C27H31FN6OPureza:98.1% - 99.37%Cor e Forma:SolidPeso molecular:474.57STAT6-IN-2
CAS:<p>STAT6-IN-2(R)-84 is a STAT6 inhibitor that inhibits the secretion of eotaxin-3 and the tyrosine phosphorylation of STAT6.</p>Fórmula:C28H31N5O2Pureza:99.67%Cor e Forma:SolidPeso molecular:469.58GNE-7883
CAS:<p>GNE-7883 is an inhibitor targeting TEAD transcription factor, inhibits cell proliferation and suppresses YAP/TAZ activation, and can be used to study YAP/TAZ-dependent tumors.</p>Fórmula:C28H29FN6O2Pureza:97.61%Cor e Forma:SolidPeso molecular:500.57
