Tirosina Quinase/Adaptador
Os inibidores de tirosina quinase e adaptadores são compostos que têm como alvo as tirosina quinases e suas proteínas adaptadoras associadas, que desempenham papéis fundamentais na sinalização celular, crescimento e diferenciação. Esses inibidores são ferramentas essenciais na pesquisa sobre o câncer, pois muitas tirosina quinases estão envolvidas nas vias de sinalização que impulsionam o crescimento e a metástase dos tumores. Ao inibir as tirosina quinases, esses compostos podem bloquear cascatas de sinalização críticas, oferecendo potenciais estratégias terapêuticas para vários tipos de câncer e outras doenças que envolvem sinalização celular anormal. Na CymitQuimica, oferecemos uma ampla gama de inibidores de tirosina quinase e adaptadores de alta qualidade para apoiar sua pesquisa em oncologia, biologia molecular e desenvolvimento de terapias direcionadas.
Subcategorias de "Tirosina Quinase/Adaptador"
- ALK(112 produtos)
- CSF-1R(42 produtos)
- EGFR(572 produtos)
- Receptor de Efrina(23 produtos)
- FLT(92 produtos)
- Receptor do Factor de Crescimento Fibroblasto (FGFR)(170 produtos)
- HER(5 produtos)
- Hck(3 produtos)
- IGF-1R(86 produtos)
- PDGFR(126 produtos)
- PYK2(7 produtos)
- Src(78 produtos)
- Receptor TAM(32 produtos)
- Tie-2(20 produtos)
- Receptor TrK(59 produtos)
- Tirosina Quinases(27 produtos)
- VEGFR(268 produtos)
- c-Fms(108 produtos)
- c-Kit(101 produtos)
- c-Met/HGFR(128 produtos)
- c-RET(51 produtos)
Exibir 13 mais subcategorias
Foram encontrados 1375 produtos de "Tirosina Quinase/Adaptador"
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EGFR-IN-129
<p>EGFR-IN-129 (Compound 10b) is an effective, selective EGFR inhibitor with an IC50 of 51.2 nM and demonstrates broad-spectrum antiproliferative activity against the NCI tumor panel.</p>Fórmula:C21H18N4O3SCor e Forma:SolidPeso molecular:406.46Cofetuzumab
CAS:<p>Cofetuzumab (PF-06523435) is a antibody targeting protein tyrosine kinase 7 (PTK7), which can be used to synthesize ADC compounds like cofetuzumab pelidotin.</p>Pureza:>95%Cor e Forma:LiquidDS06652923
<p>DS06652923 is an orally active inhibitor targeting EGFR triple mutations. It exhibits growth-inhibitory effects on Ba/F3EGFRdel19/T90M/C795S cells, with a GI50 value of 9.4 nM. Additionally, DS06652923 induces tumor regression in the Ba/F3 syngeneic transplantation model.</p>Cor e Forma:Odour SolidU3-1565
<p>U3-1565 (Anti-HB-EGF antibody) is an antibody targeting HB-EGF with potential anti-tumor activity, used in the study of advanced solid tumors.</p>Cor e Forma:LiquidPeso molecular:144.82 kDa (Predicted)MS9427
CAS:<p>MS9427: PROTAC EGFR degrader, 7.1 nM (WT), 4.3 nM (L858R); targets mutant via UPS and autophagy; inhibits NSCLC cell growth; anticancer research.</p>Fórmula:C48H58ClFN8O12Cor e Forma:SolidPeso molecular:993.47Zenocutuzumab
CAS:<p>Zenocutuzumab (MCLA-128) is a humanized antibody targeting HER2, used for research on tumors driven by NRG1 gene rearrangement.</p>Pureza:97%Cor e Forma:LiquidTimigutuzumab
CAS:<p>Timigutuzumab (GEXMab73) is a humanized monoclonal antibody designed to target ErbB2, showing potential application in cancer research [1].</p>Cor e Forma:LiquidIGF-I (30-41)
CAS:<p>IGF-I (30-41) is amino acids 30 to 41 fragment of Insulin-like Growth Factor I (IGF-I).</p>Fórmula:C51H83N19O19Pureza:98%Cor e Forma:SolidPeso molecular:1266.34Gefitinib N-oxide hydrochloride
<p>Gefitinib N-oxide hydrochloride is an N-oxide of EGFR inhibitor Gefitinib with IC50 of 2-37 nM.</p>Fórmula:C22H24ClFN4O41·5HClCor e Forma:SolidPeso molecular:517.59KRAS G12D inhibitor 25
CAS:<p>KRAS G12D inhibitor 25 (Compound 148) acts as an inhibitor for KRAS G12C and HSP90α, displaying IC50 values of <0.1 μM and 0.1-1 μM respectively. Additionally, it suppresses the proliferation of MIA PaCa-2 and NCI-H358 cell lines, with EC50 values of <0.1 μM and 0.1-1 μM correspondingly. This compound also promotes the degradation of ERBB2, exhibiting a DC50 of 0.1-1 μM.</p>Fórmula:C56H62ClN11O6Cor e Forma:SolidPeso molecular:1020.62Proinsulin C-peptide (human)
CAS:<p>C-peptide, a 31-amino acid, links Proinsulin A & B chains for correct folding and function.</p>Fórmula:C129H211N35O48Pureza:98%Cor e Forma:SolidPeso molecular:3020.26Fosgonimeton acetate
<p>Fosgonimeton acetate is an agonist of hepatocyte growth factor (HGF).</p>Fórmula:C29H49N4O10PPureza:98.01%Cor e Forma:SolidPeso molecular:644.69SJF 1521
CAS:<p>SJF 1521 is an EGFR degrader belonging to the PROTAC class that selectively degrades EGFR while preserving HER2.</p>Fórmula:C57H61ClFN7O9SPureza:99.20%Cor e Forma:SolidPeso molecular:1074.65CN009543V
CAS:<p>CN009543V is an enhancer of tyrosine phosphorylation of EGFR via downstream signaling pathways.</p>Fórmula:C12H12N4O6SCor e Forma:SolidPeso molecular:340.31GIP (3-42), human acetate
<p>GIP (3-42), human acetate is an antagonist of a glucose-dependent insulinotropic polypeptide (GIP) receptor and regulates insulin secretion and GIP metabolism</p>Pureza:98%Cor e Forma:Liquid3-Hydroxy Midostaurin
CAS:<p>3-Hydroxy Midostaurin (CGP 52421), a PKC412 metabolite, inhibits FMS-like tyrosine kinase-3 (FLT3) autophosphorylation with IC50 values of roughly 132 nM in</p>Fórmula:C35H30N4O5Pureza:98%Cor e Forma:SolidPeso molecular:586.648Eflapegrastim
CAS:<p>Eflapegrastim: humanized IgG4 antibody and G-CSF that boosts neutrophils and shortens neutropenia.</p>Cor e Forma:LiquidDepatuxizumab MMAF
<p>Depatuxizumab-MMAF, an antibody-drug conjugate (ADC), comprises an EGFR-targeted antibody linked to McMMAF and is utilized in glioblastoma research.</p>Cor e Forma:LiquidPeso molecular:148.24 kDaAMG-820
<p>AMG-820 is a human antibody targeting CSF-1R, inhibiting the binding of ligands CSF1 and IL34, and preventing subsequent ligand-induced receptor activation. For AMG-820's isotype control, refer to [Human IgG2 kappa, Isotype Control].</p>Cor e Forma:Odour LiquidcFMS Receptor Inhibitor IV
CAS:<p>cFMS Receptor Inhibitor IV is an inhibitor of c-Fms tyrosine kinase.</p>Fórmula:C22H26N4O2Pureza:99.70%Cor e Forma:SolidPeso molecular:378.47Anti-ERBB3/HER3 (29Z6)
<p>Anti-ERBB3/HER3 (29Z6) is an antibody inhibitor targeting human ERBB3/HER3.</p>Cor e Forma:Odour LiquidARRY-380 (analog )
CAS:<p>ARRY-380 analog (HER2-Inhibitor-1) is a potent and selective HER2 inhibitor.</p>Fórmula:C29H27N7O4SPureza:99.82%Cor e Forma:SolidPeso molecular:569.63BMS-777607
CAS:<p>BMS-777607 is a Met-related inhibitor for c-Met, Axl, Ron and Tyro3.</p>Fórmula:C25H19ClF2N4O4Pureza:98.16% - 98.56%Cor e Forma:SolidPeso molecular:512.89Matuzumab
CAS:<p>Matuzumab (EMD 72000) is a humanized monoclonal antibody targeting EGFR that can be used to study non-small cell lung cancer.</p>Pureza:95%Cor e Forma:LiquidPeso molecular:145.9 kDaCetuximab (PBS)
<p>Cetuximab (PBS) is a human IgG1 monoclonal antibody that inhibits the epidermal growth factor receptor (EGFR), with a dissociation constant (Kd) of 0.201 nM for EGFR as measured by the SPR method. It exhibits potent antitumor activity.</p>Cor e Forma:Odour LiquidModotuximab
CAS:<p>Modotuximab (DS 1024) is a humanized antibody targeting EGFR with antitumor activity that accelerates the internalization and degradation of EGFR.</p>Pureza:95.5% (SDS-PAGE); 99.3% (SEC-HPLC) - 95.5% (SDS-PAGE); 99.3% (SEC-HPLC)Cor e Forma:LiquidBMS-599626
CAS:<p>BMS-599626 (AC480) has been used in trials studying the treatment of Cancer, Metastases, and HER2 or EGFR Expressing Advanced Solid Malignancies.</p>Fórmula:C27H27FN8O3Pureza:98.73%Cor e Forma:SolidPeso molecular:530.55VEGFR-2-IN-55
<p>VEGFR-2-IN-55 (Compound 30) is an effective VEGFR-2 kinase inhibitor with an IC50 of 1.24 nM and exhibits anti-tumor activity.</p>Cor e Forma:Odour SolidErlotinib-d6
CAS:<p>Erlotinib is a directly acting inhibitor EGFR tyrosine kinase inhibitor with an IC50 of 2 nM for human EGFR. Erlotinib D6 is a deuterium labeled Erlotinib .</p>Fórmula:C22H23N3O4Pureza:98%Cor e Forma:SolidPeso molecular:399.47(3S,4S)-PF-06459988
CAS:<p>(3S, 4S)-PF-06459988, a less active S enantiomer, specifically inhibits T790M mutant EGFR with high selectivity.</p>Fórmula:C19H22ClN7O3Cor e Forma:SolidPeso molecular:431.88SB-505124
CAS:Fórmula:C20H21N3O2Pureza:>98.0%(HPLC)Cor e Forma:White to Light yellow to Light orange powder to crystalinePeso molecular:335.41SYN1143
CAS:<p>SYN1143 (AMG-1) strongly inhibits RON & c-Met with IC50s: 9 & 4 nmol/L.</p>Fórmula:C31H29FN4O5Pureza:99.69%Cor e Forma:SolidPeso molecular:556.58Tucatinib hemiethanolate
CAS:<p>Tucatinib (Irbinitinib) hemiethanolate is a potent, orally active and selective HER2 inhibitor with an IC50 of 8 nM.</p>Fórmula:C54H54N16O5Pureza:99.76%Cor e Forma:SolidPeso molecular:1007.11CL-387785
CAS:Fórmula:C18H13BrN4OPureza:>98.0%(GC)Cor e Forma:White to Light yellow powder to crystalPeso molecular:381.23Lapatinib Ditosylate
CAS:Fórmula:C29H26ClFN4O4S·2C7H8O3SPureza:>98.0%(T)(HPLC)Cor e Forma:White to Light yellow powder to crystalPeso molecular:925.46Trapidil
CAS:Fórmula:C10H15N5Pureza:>98.0%(HPLC)(qNMR)Cor e Forma:White to Light yellow powder to crystalPeso molecular:205.27MNS
CAS:Fórmula:C9H7NO4Pureza:>98.0%(GC)Cor e Forma:Light yellow to Yellow to Green powder to crystalPeso molecular:193.16AP23846
CAS:<p>AP23846 is an Src family kinase inhibitor that reduces vascular endothelial growth factor and interleukin-8 expression in human solid tumor cell lines.</p>Fórmula:C24H34N5OPPureza:97.83%Cor e Forma:SolidPeso molecular:439.53PD 173074
CAS:Fórmula:C28H41N7O3Pureza:>95.0%(HPLC)Cor e Forma:White to Yellow to Orange powder to crystalPeso molecular:523.68EGFR Protein, Human, Recombinant (His & Avi), FITC-Labeled
<p>EGFR Protein, Human, Recombinant (His & Avi), FITC-Labeled is expressed in HEK293 mammalian cells with C-His-Avi tag.</p>Cor e Forma:Lyophilized PowderPeso molecular:71.5 kDa (predicted). Due to glycosylation, the protein migrates to 90-115 kDa based on Tris-Bis PAGE result.EGFR Protein, Human, Recombinant (His & Avi), Biotinylated
<p>EGFR Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with C-His-Avi tag.</p>Cor e Forma:Lyophilized PowderPeso molecular:71.5 kDa (predicted). Due to glycosylation, the protein migrates to 90-120 kDa based on Tris-Bis PAGE result.EGFRVIII Protein, Human, Recombinant (His & Avi), FITC-Labeled
<p>The epidermal growth factor receptor (EGFR) is overexpressed in a variety of human epithelial tumors, often as a consequence of gene amplification.</p>Cor e Forma:Lyophilized PowderPeso molecular:41.6 kDa (predicted). Due to glycosylation, the protein migrates to 68-80 kDa based on Tris-Bis PAGE result.1-Naphthyl PP1
CAS:Fórmula:C19H19N5Pureza:>98.0%(T)(HPLC)Cor e Forma:White to Light yellow powder to crystalPeso molecular:317.40EGFRVIII Protein, Human, Recombinant (His & Avi)
<p>The epidermal growth factor receptor (EGFR) is overexpressed in a variety of human epithelial tumors, often as a consequence of gene amplification.</p>Cor e Forma:Lyophilized PowderPeso molecular:41.6 kDa (predicted). Due to glycosylation, the protein migrates to 68-80 kDa based on Tris-Bis PAGE result.AG 1478 Hydrochloride
CAS:Fórmula:C16H14ClN3O2·HClPureza:>95.0%(T)(HPLC)Cor e Forma:White to Light yellow powder to crystalPeso molecular:352.22EGFR vIII Protein, Human, Recombinant (His & Avi), Biotinylated
<p>EGFR vIII Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with C-6xHis-Avi tag.</p>Cor e Forma:Lyophilized PowderPeso molecular:60-90 KDa (reducing condition)EGFR vIII Protein, Human, Recombinant (His)
<p>EGFR vIII Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with C-6xHis tag.</p>Cor e Forma:Lyophilized PowderPeso molecular:61-75 Kda (reducing condition)EGFRVIII Protein, Human, Recombinant (His & Avi), PE-Labeled
<p>The epidermal growth factor receptor (EGFR) is overexpressed in a variety of human epithelial tumors, often as a consequence of gene amplification.</p>Cor e Forma:Lyophilized PowderPeso molecular:41.6 kDa (predicted)Vatalanib Succinate
CAS:Fórmula:C20H15ClN4·C4H6O4Pureza:>98.0%(T)(HPLC)Cor e Forma:White to Light yellow to Light orange powder to crystalPeso molecular:464.91Rilematovir
CAS:<p>Rilematovir (JNJ-678) inhibits fusion protein, has antiviral properties, low toxicity, and targets RSV treatment.</p>Fórmula:C21H20ClF3N4O3SPureza:99.82%Cor e Forma:SolidPeso molecular:500.92EGFRVIII Protein, Human, Recombinant (His & Avi), Biotinylated
<p>The epidermal growth factor receptor (EGFR) is overexpressed in a variety of human epithelial tumors, often as a consequence of gene amplification.</p>Cor e Forma:Lyophilized PowderPeso molecular:41.6 kDa (predicted). Due to glycosylation, the protein migrates to 60-78 kDa based on Tris-Bis PAGE result.Tyrphostin AG 1478
CAS:Fórmula:C16H14ClN3O2Pureza:>98.0%(HPLC)Cor e Forma:Light orange to Yellow to Green powder to crystalPeso molecular:315.76SU 5416
CAS:Fórmula:C15H14N2OPureza:>98.0%(T)(HPLC)Cor e Forma:White to Yellow to Orange powder to crystalPeso molecular:238.29PD-161570
CAS:Fórmula:C26H35Cl2N7OPureza:>98.0%(HPLC)Cor e Forma:White to Light yellow powder to crystalPeso molecular:532.51EGFR vIII Protein, Human, Recombinant (hFc)
<p>EGFR vIII Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with C-Fc tag.</p>Cor e Forma:Lyophilized PowderPeso molecular:90-120 KDa (reducing condition)AEE 788
CAS:Fórmula:C27H32N6Pureza:>98.0%(HPLC)Cor e Forma:White to Light yellow powder to crystalPeso molecular:440.60EGFR Protein, Human, Recombinant (His & Avi)
<p>EGFR Protein, Human, Recombinant (His & Avi) is expressed in HEK293 mammalian cells with C-His-Avi tag.</p>Cor e Forma:Lyophilized PowderPeso molecular:71.5 kDa (predicted). Due to glycosylation, the protein migrates to 85-110 kDa based on Tris-Bis PAGE result.EGFR Protein, Rhesus macaque, Recombinant (His)
<p>EGFR Protein, Rhesus macaque, Recombinant (His) is expressed in HEK293 mammalian cells with C-His tag.</p>Cor e Forma:Lyophilized PowderPeso molecular:69.8 kDa (predicted). Due to glycosylation, the protein migrates to 85-100 kDa based on Tris-Bis PAGE result.PF-06737007
CAS:<p>PF-06737007 is an effective inhibitor of pan-Trk in cell-based assays (IC50s: 7.7 nM, 15 nM, and 3.9 nM for TrkA, TrkB, and TrkC, respectively).</p>Fórmula:C25H28F4N2O6Pureza:98%Cor e Forma:SolidPeso molecular:528.49Tyrphostin RG 14620
CAS:Fórmula:C14H8Cl2N2Pureza:>98.0%(HPLC)Cor e Forma:White to Light yellow powder to crystalPeso molecular:275.13Anti-Src Antibody (1E789)
<p>Anti-Src Antibody (1E789) is an antibody targeting Src. Anti-Src Antibody (1E789) can be used in ELISA, WB, IF, FCM.</p>Cor e Forma:Odour LiquidAnti-EGFR Antibody (3B845)
<p>Anti-EGFR Antibody (3B845) is an antibody targeting EGFR. Anti-EGFR Antibody (3B845) can be used in ELISA, WB, IHC.</p>Cor e Forma:Odour LiquidAnti-Phospho-EGFR (Tyr1092) Antibody (9I899)
<p>Anti-Phospho-EGFR (Tyr1092) Antibody (9I899) is an antibody targeting Phospho-EGFR (Tyr1092). Anti-Phospho-EGFR (Tyr1092) Antibody (9I899) can be used in ELISA, WB.</p>Cor e Forma:Odour LiquidAnti-EGFR Antibody (7X976)
<p>Anti-EGFR Antibody (7X976) is an antibody targeting EGFR. Anti-EGFR Antibody (7X976) can be used in ELISA, WB, IHC, IF, FCM.</p>Cor e Forma:Odour LiquidAnti-EGFR Antibody (9S619)
<p>Anti-EGFR Antibody (9S619) is an antibody targeting EGFR. Anti-EGFR Antibody (9S619) can be used in ELISA, IHC, FCM.</p>Cor e Forma:Odour LiquidAnti-Phospho-EGFR (Tyr1068) Antibody (3Q245)
<p>Anti-Phospho-EGFR (Tyr1068) Antibody (3Q245) is an antibody targeting Phospho-EGFR (Tyr1068). Anti-Phospho-EGFR (Tyr1068) Antibody (3Q245) can be used in ELISA, WB.</p>Cor e Forma:Odour LiquidSU 1498
CAS:Fórmula:C25H30N2O2Pureza:>98.0%(HPLC)Cor e Forma:White to Orange to Green powder to crystalPeso molecular:390.53Mubritinib
CAS:Fórmula:C25H23F3N4O2Pureza:>98.0%(HPLC)Cor e Forma:White to Gray to Brown powder to crystalPeso molecular:468.48NSC 12
CAS:<p>NSC 12 is an orally active pan-FGF trap that binds FGF2 and interferes with its interaction with FGFR1 with potential FGF-dependent antitumor activity.</p>Fórmula:C24H34F6O3Pureza:99.51%Cor e Forma:SolidPeso molecular:484.52DT-3 acetate
<p>DT-3 acetate is a cell-permeable peptide that acts as an inhibitor of protein kinase G (PKGIα), effectively blocking the cGMP-PKG signaling pathway.</p>Fórmula:C152H258N52O28S·xC2H4O2Cor e Forma:SolidPeso molecular:3294.07 (free acid)Bosutinib
CAS:Fórmula:C26H29Cl2N5O3Pureza:>95.0%(T)(HPLC)Cor e Forma:White to Light yellow powder to crystalPeso molecular:530.45AG-1296
CAS:Fórmula:C16H14N2O2Pureza:>98.0%(GC)Cor e Forma:White to Orange to Green powder to crystalPeso molecular:266.30PP 1
CAS:Fórmula:C16H19N5Pureza:>98.0%(T)(HPLC)Cor e Forma:White to Light yellow powder to crystalPeso molecular:281.36Neratinib
CAS:Fórmula:C30H29ClN6O3Pureza:>95.0%(T)(HPLC)Cor e Forma:White to Light yellow powder to crystalPeso molecular:557.05Rociletinib hydrobromide
CAS:<p>Rociletinib hydrobromide is an orally delivered inhibitor of the mutant form of EGFR kinase (Kis: 21.5 nM and 303.3 nM for EGFR L858R/T790M and EGFR WT).</p>Fórmula:C27H29BrF3N7O3Pureza:98%Cor e Forma:SolidPeso molecular:636.46PD 158780
CAS:Fórmula:C14H12BrN5Pureza:>97.0%(HPLC)Cor e Forma:White to Yellow to Green powder to crystalPeso molecular:330.19Pazopanib
CAS:Fórmula:C21H23N7O2SPureza:>98.0%(T)(HPLC)Cor e Forma:White to Light yellow powder to crystalPeso molecular:437.52Motesanib
CAS:Fórmula:C22H23N5OPureza:>95.0%(HPLC)(qNMR)Cor e Forma:White to Light yellow powder to crystalPeso molecular:373.46Canertinib
CAS:Fórmula:C24H25ClFN5O3Pureza:>98.0%(HPLC)(qNMR)Cor e Forma:White to Light yellow powder to crystalPeso molecular:485.94Cediranib
CAS:Fórmula:C25H27FN4O3Pureza:>95.0%(T)(HPLC)Cor e Forma:White to Light yellow powder to crystalPeso molecular:450.51Vandetanib
CAS:Fórmula:C22H24BrFN4O2Pureza:>98.0%(T)(HPLC)Cor e Forma:White to Light yellow powder to crystalPeso molecular:475.36BAY-826
CAS:<p>BAY-826 is a novel, potent and selective TIE-2 inhibitor that inhibits TIE-2 phosphorylation and can be used to study tumors.</p>Fórmula:C26H19F5N6OSPureza:98% - 99.28%Cor e Forma:SolidPeso molecular:558.53Sunitinib Malate
CAS:Fórmula:C22H27FN4O2·C4H6O5Pureza:>98.0%(HPLC)Cor e Forma:Light yellow to Brown powder to crystalPeso molecular:532.57Imatinib Mesylate
CAS:Fórmula:C29H31N7O·CH4O3SPureza:>98.0%(HPLC)Cor e Forma:White to Light yellow powder to crystalPeso molecular:589.72SB-525334
CAS:Fórmula:C21H21N5Pureza:>98.0%(HPLC)Cor e Forma:White to Yellow to Orange powder to crystalPeso molecular:343.43PLX647
CAS:<p>PLX647 is a highly selective dual FMS/KIT kinase inhibitor (IC50: 28/16 nM).</p>Fórmula:C21H17F3N4Pureza:99.38%Cor e Forma:SolidPeso molecular:382.38Nintedanib
CAS:Fórmula:C31H33N5O4Pureza:>95.0%(T)(HPLC)Cor e Forma:White to Yellow to Yellow green powder to crystalPeso molecular:539.64Linifanib
CAS:Fórmula:C21H18FN5OPureza:>95.0%(HPLC)(qNMR)Cor e Forma:White to Light yellow powder to crystalPeso molecular:375.41PF-04217903 methanesulfonate
CAS:<p>PF-04217903 methanesulfonate is a potent ATP-competitive inhibitor of c-Met kinase (Ki of 4.8 nM for human c-Met).</p>Fórmula:C20H20N8O4SPureza:98%Cor e Forma:SolidPeso molecular:468.49GDC-0834
CAS:<p>GDC-0834 inhibits BTK with an in vitro IC50 of 5.9 and 6.4 nM in biochemical and cellular assays, respectively, and in vivo IC50 of 1.1 and 5.6 μM in mouse and</p>Fórmula:C33H36N6O3SCor e Forma:SolidPeso molecular:596.74Mavelertinib
CAS:<p>Mavelertinib (PF-06747775) is an EGFR tyrosine kinase (EGFR TKI) inhibitor that inhibits T790M/L858R and can be used to study tumours.</p>Fórmula:C18H22FN9O2Pureza:99.89%Cor e Forma:SolidPeso molecular:415.42AV-412 free base
CAS:<p>AV-412 free base is an EGFR inhibitor (IC50s: 0.75, 0.79, 0.5, 2.3, 19 nM for EGFR, EGFR(T790M), EGFR(L858R), EGFR(L858R/T790M) and ErbB2).</p>Fórmula:C27H28ClFN6OCor e Forma:SolidPeso molecular:507Neratinib maleate
CAS:<p>Neratinib maleate is a selective HER2/EGFR inhibitor (IC50: 59/92 nM) used in breast and prostate cancer studies.</p>Fórmula:C34H33ClN6O7Pureza:99.64%Cor e Forma:SolidPeso molecular:673.11N-Desethyl Sunitinib
CAS:<p>N-Desethyl Sunitinib (SU012662) is inhibitor of tyrosine kinases tumor proliferation and angiogenesis, including VEGFR, PDGFR, KIT, and FLT3,</p>Fórmula:C20H23FN4O2Pureza:98%Cor e Forma:SolidPeso molecular:370.42Lanraplenib succinate
CAS:<p>Lanraplenib succinate is an oral SYK inhibitor (IC50=9.5 nM) that doesn't extend BT, targeting GPVI in platelets for inflammation treatment.</p>Fórmula:C58H68N18O14Cor e Forma:SolidPeso molecular:1241.294SB1317
CAS:<p>SB1317 (TG02) is a potent inhibitor of cyclin dependant kinases (CDKs), Janus kinase 2 (JAK2), and Fms-like tyrosine kinase-3 (FLT3).</p>Fórmula:C23H24N4OPureza:99.86%Cor e Forma:SolidPeso molecular:372.46BPR1K871
CAS:<p>BPR1K871, a preclinical development candidate for anti-cancer therapy [1], is a potent, selective dual inhibitor targeting FLT3 and AURKA, with IC50 values of</p>Fórmula:C25H28ClN7O2SCor e Forma:SolidPeso molecular:526.05Osimertinib dimesylate
CAS:<p>Osimertinib dimesylate is an irreversible and mutant selective EGFR inhibitor (IC50s: 12 and 1 nM against EGFR L858R and EGFR L858R/T790M).</p>Fórmula:C30H41N7O8S2Pureza:98%Cor e Forma:SolidPeso molecular:691.82SU14813 maleate
CAS:<p>SU14813 maleate is an inhibitor of multi-targeted receptor tyrosine kinases (IC50s: 2, 50, 4, 15 nM for VEGFR1, VEGFR2, PDGFRβ, and KIT).</p>Fórmula:C27H31FN4O8Pureza:98%Cor e Forma:SolidPeso molecular:558.56BI-4142
CAS:<p>BI-4142 is a HER2 inhibitor that inhibits cancer cell proliferation, suppresses her2-dependent cell lines and inhibits downstream signalling.</p>Fórmula:C28H27N9O2Pureza:97.21% - 98.09%Cor e Forma:SolidPeso molecular:521.57Cediranib Maleate
CAS:Fórmula:C25H27FN4O3·C4H4O4Pureza:>98.0%(T)(HPLC)Cor e Forma:White to Light yellow powder to crystalPeso molecular:566.59JK-P3
CAS:Fórmula:C18H17N3O3Pureza:>98.0%(T)(HPLC)Cor e Forma:White to Light yellow to Light orange powder to crystalPeso molecular:323.35Saracatinib
CAS:Fórmula:C27H32ClN5O5Pureza:>95.0%(HPLC)(qNMR)Cor e Forma:White to Light yellow to Light orange powder to crystalPeso molecular:542.03Tyrphostin AG 879
CAS:Fórmula:C18H24N2OSPureza:>98.0%(HPLC)Cor e Forma:Light yellow to Yellow to Orange powder to crystalPeso molecular:316.46trans-Pralsetinib
CAS:<p>trans-Pralsetinib (trans-BLU-667) is an inhibitor of rearranged during transfection (RET).</p>Fórmula:C27H32FN9O2Pureza:98%Cor e Forma:SolidPeso molecular:533.6Nilotinib
CAS:Fórmula:C28H22F3N7OPureza:>95.0%(T)(HPLC)Cor e Forma:White to Light yellow powder to crystalPeso molecular:529.53PD 0325901
CAS:Fórmula:C16H14F3IN2O4Pureza:>97.0%(T)(HPLC)Cor e Forma:White to Light yellow powder to crystalPeso molecular:482.20DDR1-IN-4
CAS:<p>DDR1-IN-4 is a DDR1 inhibitor that inhibits autophosphorylation of DDR1 and DDR2 and can be used to study chronic kidney disease.</p>Fórmula:C23H20BrF3N6O3Pureza:97.25%Cor e Forma:SolidPeso molecular:565.34PQ401
CAS:Fórmula:C18H16ClN3O2Pureza:>98.0%(HPLC)Cor e Forma:White to Yellow to Orange powder to crystalPeso molecular:341.80Hypericin
CAS:Fórmula:C30H16O8Pureza:>95.0%(HPLC)Cor e Forma:Black powder to crystalPeso molecular:504.45A-770041
CAS:<p>A-770041 is an Lck inhibitor, YZ inhibits the production of IL-2 stimulated by concanavalin A in whole blood, and can prevent cardiac allograft rejection.</p>Fórmula:C34H39N9O3Pureza:99.23% - 99.86%Cor e Forma:SolidPeso molecular:621.73Pazopanib Hydrochloride
CAS:Fórmula:C21H23N7O2S·HClPureza:>95.0%(T)(HPLC)Cor e Forma:White to Almost white powder to crystalPeso molecular:473.98HNMPA-(AM)3
CAS:<p>HNMPA-(AM)3 抑制 ERK 磷酸化的激活以及促促胸腺激素 (PTTH) 刺激蜕皮类固醇产生。 此外，HNMPA-(AM)3 对蜕皮类固醇产生 (IC50=14.2 μM) 和胰岛素受体活性 (IC50=14.2 μM 和 200 μM，在蚊子和哺乳动物中分别) 具有抑制作用。</p>Fórmula:C20H23O10PPureza:97.22%Cor e Forma:SolidPeso molecular:454.36WHI-P180 Hydrochloride
CAS:Fórmula:C16H15N3O3·HClPureza:>97.0%(T)(HPLC)Cor e Forma:White to Light gray to Light yellow powder to crystalPeso molecular:333.77PP 2
CAS:Fórmula:C15H16ClN5Pureza:>97.0%(T)(HPLC)Cor e Forma:White to Light yellow powder to crystalPeso molecular:301.78Regorafenib
CAS:Fórmula:C21H15ClF4N4O3Pureza:>98.0%(HPLC)Cor e Forma:White to Light yellow to Light orange powder to crystalPeso molecular:482.82SM27
CAS:<p>SM27 is a fibroblast growth factor 2 (FGF2) inhibitor with anti-angiogenic activity and can be used to study tumours.</p>Fórmula:C21H16N2O9S2Pureza:98.83%Cor e Forma:SolidPeso molecular:504.49Tyrphostin A9
CAS:Fórmula:C18H22N2OPureza:>98.0%(GC)Cor e Forma:Light orange to Yellow to Green powder to crystalPeso molecular:282.39WHI-P154
CAS:Fórmula:C16H14BrN3O3Pureza:>98.0%(HPLC)Cor e Forma:White to Yellow to Orange powder to crystalPeso molecular:376.21Tyrphostin 8
CAS:<p>Tyrphostin 8(4-Hydroxybenzylidenemalononitrile) is a potent GTPase inhibitor that inhibits EGFR kinase with an IC50 of 560 μM.Tyrphostin 8 inhibits protein</p>Fórmula:C10H6N2OPureza:99.86%Cor e Forma:SolidPeso molecular:170.17Daphnetin
CAS:Fórmula:C9H6O4Pureza:>90.0%(HPLC)Cor e Forma:White to Light yellow to Light red powder to crystalPeso molecular:178.14BMS-599626
CAS:Fórmula:C27H27FN8O3Pureza:>98.0%(HPLC)Cor e Forma:White to Light yellow to Light orange powder to crystalPeso molecular:530.56Brivanib
CAS:<p>Brivanib (BMS-540215) is an ATP-competitive inhibitor against VEGFR2 with IC50 of 25 nM, moderate potency against VEGFR-1 and FGFR-1, but >240-fold against</p>Fórmula:C19H19FN4O3Pureza:98.87%Cor e Forma:SolidPeso molecular:370.38Tyrphostin RG 13022
CAS:Fórmula:C16H14N2O2Pureza:>98.0%(GC)Cor e Forma:White to Yellow to Green powder to crystalPeso molecular:266.30Anti-EGFR Monoclonal Antibody-Biotin
<p>Antibody Type: Rabbit Monoclonal<br><br>Application: FCM<br><br>Reactivity: Human</p>Pureza:> 95% as determined by SDS-PAGE.Cor e Forma:LiquidPeso molecular:150 kDaAnti-EGFR Monoclonal Antibody
<p>Antibody Type: Rabbit Monoclonal<br><br>Application: FCM<br><br>Reactivity: Human</p>Pureza:> 95% as determined by SDS-PAGE.Cor e Forma:LiquidPeso molecular:150 kDaNaquotinib
CAS:<p>Naquotinib (ASP8273) (ASP8273) is an orally available, mutant-selective and irreversible EGFR inhibitor; (IC50s: 8-33 nM and 230 nM toward EGFR mutants and EGFR</p>Fórmula:C30H42N8O3Pureza:97.49%Cor e Forma:SolidPeso molecular:562.71(Rac)-IBT6A
CAS:<p>(Rac)-IBT6A is a racemate of IBT6A. IBT6A is an impurity of Ibrutinib and can be used in the synthesis of IBT6A Ibrutinib dimer and IBT6A adduct.</p>Fórmula:C22H22N6OPureza:99.24%Cor e Forma:SolidPeso molecular:386.45squarunkinA
CAS:<p>squarunkinA is a novel modulator of the UNC119-Cargo Interaction, potently and selectively inhibiting the binding of a myristoylated peptide representing the N-</p>Fórmula:C25H32F3N5O4Pureza:99.29%Cor e Forma:SolidPeso molecular:523.55LY2874455
CAS:<p>LY2874455 has been used in trials studying the treatment of Advanced Cancer.</p>Fórmula:C21H19Cl2N5O2Pureza:97.22% - 99.46%Cor e Forma:SolidPeso molecular:444.31Protein kinase inhibitors 1
CAS:<p>Protein kinase inhibitors 1 is a novel inhibitor of HIPK2 with an IC50 of 74 nM and Kd of 9.5 nM.</p>Fórmula:C18H17N5O3SPureza:98%Cor e Forma:SolidPeso molecular:383.42Bacitracin Zinc
CAS:<p>Bacitracin Zinc is a dephosphorylated disruptor of C55-isoprene pyrophosphate that inhibits Tyr cleavage in Met-enkephalin with an IC50 of 10 μM.</p>Fórmula:C66H101N17O16SZnPureza:63.98%Cor e Forma:Light-Colored Free-Flowing PowdersPeso molecular:1486.07ZM39923 hydrochloride
CAS:<p>ZM39923 hydrochloride (JAK3 Inhibitor IV) is an JAK1/3 inhibitor, almost no activity to JAK2 and modestly potent to EGFR; also is sensitive to transglutaminase.</p>Fórmula:C23H25NO·HClPureza:98.05%Cor e Forma:SolidPeso molecular:367.91Malantide acetate(86555-35-3 free base)
<p>Malantide acetate is a dodecapeptide phosphorylated by cyclic AMP-dependent protein kinase (PKA), and increases PKA activity.Malantide is a synthetic peptide</p>Fórmula:C74H128N22O23Pureza:>99.99%Cor e Forma:SolidPeso molecular:1693.97R-268712
CAS:<p>R-268712 is a potent ALK5 inhibitor with a 2.5 nM IC50, also targeting TGF-β type I receptor orally.</p>Fórmula:C20H18FN5OPureza:99.61%Cor e Forma:SolidPeso molecular:363.39ASP5878
CAS:<p>ASP5878 potently inhibited the tyrosine kinase activities of recombinant FGFR1, 2, 3, and 4 with IC50 values of 0.47, 0.60, 0.74, and 3.5 nmol/L.</p>Fórmula:C18H19F2N5O4Pureza:99.8% - 99.89%Cor e Forma:SolidPeso molecular:407.37PP 3
CAS:<p>PP 3 is a Negative control for the Src kinase inhibitor PP 2</p>Fórmula:C11H9N5Pureza:98.61%Cor e Forma:Whit To Off-White SolidPeso molecular:211.22BMS-911543
CAS:<p>BMS-911543 is a potent and selective inhibitor of JAK2 with IC50 of 1.1 nM, ~350-, 75- and 65-fold selective to JAK1, JAK3 and TYK2, respectively. Phase 1/2.</p>Fórmula:C23H28N8OPureza:97.69% - 99.98%Cor e Forma:SolidPeso molecular:432.52Ningetinib Tosylate
CAS:<p>Ningetinib Tosylate is an orally bioavailable tyrosine kinase inhibitor with IC50s of <1.0, 1.9 and 6.7 nM for Axl, VEGFR2, and c-Met, respectively.</p>Fórmula:C38H37FN4O8SPureza:99.93%Cor e Forma:SolidPeso molecular:728.79LDN193189
CAS:<p>LDN193189 blocks BMP signaling by inhibiting ALK2/3; IC50: ALK1/2/3/6 = 0.8/0.8/5.3/16.7 nM.</p>Fórmula:C25H22N6Pureza:98% - 99.86%Cor e Forma:SolidPeso molecular:406.48FLT3-IN-2
CAS:<p>FLT3-IN-2 is an FLT3 inhibitor (IC50<1 μM).</p>Fórmula:C21H16ClF3N4Pureza:97.57% - 98.53%Cor e Forma:SolidPeso molecular:416.83Glumetinib
CAS:<p>Glumetinib (SCC244) (SCC 244) is a novel potent and selective inhibitor of c-Met kinase (IC50: 0.42 nM).</p>Fórmula:C21H17N9O2SPureza:99.79%Cor e Forma:SolidPeso molecular:459.48Fostamatinib Disodium
CAS:<p>Fostamatinib Disodium (R788 Disodium) is an orally available Syk kinase inhibitor with potential anti-inflammatory and immunomodulating activities.</p>Fórmula:C23H24FN6O9P·2NaPureza:96.13% - 99.09%Cor e Forma:SolidPeso molecular:624.42AAL-993
CAS:<p>AAL-993: VEGFR inhibitor; IC50: 130 nM (1), 23 nM (2), 18 nM (3); weak on other tyrosine kinases; antiangiogenic & antitumor.</p>Fórmula:C20H16F3N3OPureza:99.65%Cor e Forma:SolidPeso molecular:371.36MSDC 0160
CAS:<p>MSDC 0160 (CAY10415) is a prototype mTOT-modulating insulin sensitizer being used in trials studying the treatment of Type 2 Diabetes and Alzheimer's Disease.</p>Fórmula:C19H18N2O4SPureza:98.11% - 99.53%Cor e Forma:SolidPeso molecular:370.42BIBF0775
CAS:<p>BIBF0775 is a selective TGFβ type I receptor (Alk5) inhibitor (IC50: 34 nM).</p>Fórmula:C31H34N4O2Pureza:99.45% - 99.79%Cor e Forma:SolidPeso molecular:494.63Ruxolitinib (S enantiomer)
CAS:<p>Ruxolitinib S enantiomer (INCB18424) is the S-enantiomer of Ruxolitinib. Ruxolitinib is the first potent, selective JAK1/2 inhibitor.</p>Fórmula:C17H18N6Pureza:99.37% - 99.79%Cor e Forma:SolidPeso molecular:306.36AZ7550
CAS:<p>AZ7550, an active metabolite of AZD9291, inhibits the activity of IGF1R (IC50: 1.6 μM).</p>Fórmula:C27H31N7O2Pureza:97.07% - 99.75%Cor e Forma:SolidPeso molecular:485.58Tyrphostin AG 528
CAS:<p>Tyrphostin AG 528 (Tyrphostin B66) is an inhibitor of EGFR (IC50: 4.9 μM) and ErbB2 (IC50: 2.1 μM).</p>Fórmula:C18H14N2O3Pureza:99.64%Cor e Forma:SolidPeso molecular:306.32JCN037
CAS:<p>JCN037 is potent, non-covalent and brain-penetrant inhibitor of EGFR(EGFR, p-wtEGFR and pEGFRvⅢ with IC50 of 2.49 nM, 3.95 nM, 4.48 nM , respectively).</p>Fórmula:C16H11BrFN3O2Pureza:99.5%Cor e Forma:SolidPeso molecular:376.185'-Fluoroindirubinoxime
CAS:<p>5'-Fluoroindirubinoxime (5'-FIO) is a potent FLT3 inhibitor( IC50 : 15 nM).</p>Fórmula:C16H10FN3O2Pureza:>99.99%Cor e Forma:SolidPeso molecular:295.27FIIN-3
CAS:<p>FIIN-3 is an irreversible inhibitor of FGFR.</p>Fórmula:C34H36Cl2N8O4Pureza:97.63% - 98.92%Cor e Forma:SolidPeso molecular:691.61Osimertinib mesylate
CAS:<p>Osimertinib mesylate (AZD-9291 mesylate) is an EGFR third-generation inhibitor. Osimertinib mesylate has antitumor activity. Cost-effective and quality-assured.</p>Fórmula:C29H37N7O5SPureza:99.46% - >99.99%Cor e Forma:SolidPeso molecular:595.71GSK1838705A
CAS:<p>GSK1838705A: IGF-1R inhibitor (IC50=2.0nM), IR (1.6nM), ALK (0.5nM), minimal other kinase impact.</p>Fórmula:C27H29FN8O3Pureza:98.89% - >99.99%Cor e Forma:SolidPeso molecular:532.57Tyrphostin A9
CAS:<p>Tyrphostin A9 (SF 6847) is an Agricultural acaricide, now superseded. Tyrphostin A9 is firstly designed as an EGFR inhibitor</p>Fórmula:C18H22N2OPureza:98.21% - 99.87%Cor e Forma:Yellow SolidPeso molecular:282.38Dovitinib lactate
CAS:<p>Dovitinib lactate (TKI-258 lactate)(TKI258) lactate is a potent inhibitor of fibroblast growth factor receptor 3 (FGFR3) (IC50 :5 nM).</p>Fórmula:C24H27FN6O4Pureza:99.54% - 99.77%Cor e Forma:SolidPeso molecular:482.51Neratinib
CAS:<p>Neratinib (HKI-272) (HKI-272) is an orally available, irreversible tyrosine kinase inhibitor for HER2 and EGFR (IC50: 59/92 nM), respectively.</p>Fórmula:C30H29ClN6O3Pureza:96.17% - 99.85%Cor e Forma:SolidPeso molecular:557.04(E/Z)-Zotiraciclib
CAS:<p>(E/Z)-Zotiraciclib ((E/Z)-TG02) inhibits CDK2, JAK2, and FLT3 effectively with IC50s of 13, 73, and 56 nM, respectively.</p>Fórmula:C23H24N4OPureza:97.75% - 99.92%Cor e Forma:SolidPeso molecular:372.46(E)-AG 99
CAS:<p>(E)-AG 99 ((E)-Tyrphostin AG 99) is an inhibitor of EGFR kinase (IC50: 10 μM in the human epidermoid carcinoma cell line A431).</p>Fórmula:C10H8N2O3Pureza:99.23%Cor e Forma:SolidPeso molecular:204.18Entrectinib
CAS:<p>Entrectinib (RXDX-101) is an orally Trk, ROS1, and ALK inhibitor. Entrectinib exhibits antitumor activity. Cost-effective and quality-assured.</p>Fórmula:C31H34F2N6O2Pureza:98.03% - 99.61%Cor e Forma:SolidPeso molecular:560.64AG-494
CAS:<p>AG-494 (Tyrphostin B48) is an inhibitor of epidermal growth factor receptor kinase.</p>Fórmula:C16H12N2O3Pureza:98.69%Cor e Forma:SolidPeso molecular:280.28CP-724714
CAS:<p>CP-724714 (CP724714) is an effective and selective HER2/ErbB2 inhibitor (IC50: 10 nM), >640-fold selectivity against EGFR, Abl, InsR, PDGFR, IRG-1R, Src, VEGFR2</p>Fórmula:C27H27N5O3Pureza:97.1% - 98.82%Cor e Forma:SolidPeso molecular:469.54HPK1-IN-2
CAS:<p>HPK1-IN-2 is a strong, oral HPK1 inhibitor (IC50<0.05 μM), also blocking Lck, Flt3 kinases, with anticancer properties.</p>Fórmula:C19H20N6OSPureza:97.31%Cor e Forma:SolidPeso molecular:380.47RG14620
CAS:<p>RG14620 (Tyrphostin RG14620) is an epidermal growth factor receptor (EGFR) inhibitor.</p>Fórmula:C14H8Cl2N2Pureza:99.82% - 99.87%Cor e Forma:SolidPeso molecular:275.13UNC2541
CAS:<p>UNC2541 is a potent and Mer tyrosine kinase (MerTK)-specific inhibitor.</p>Fórmula:C24H34FN7O2Pureza:98.33%Cor e Forma:SolidPeso molecular:471.57AG-13958
CAS:<p>AG-13958 (AG-013958) (AG-013958), a potent VEGFR tyrosine kinase inhibitor, for the treatment of age-related macular degeneration.</p>Fórmula:C26H22FN7OPureza:99.4%Cor e Forma:SolidPeso molecular:467.5G5-7
CAS:<p>G5-7 is an oral JAK2 inhibitor targeting EGFR/STAT3 phosphorylation with potential for glioma research.</p>Fórmula:C22H19F2NO3Pureza:97.3%Cor e Forma:SolidPeso molecular:383.39AZD8931 diFuMaric acid
CAS:<p>AZD8931 is a reversible and ATP competitive inhibitor of EGFR, ErbB2 and ErbB3 (IC50 of 4 nM, 3 nM and 4 nM, respectively).</p>Fórmula:C31H33ClFN5O11Pureza:99.92%Cor e Forma:SolidPeso molecular:706.1Theliatinib
CAS:<p>Theliatinib: potent, selective EGFR inhibitor, anti-tumor; Ki=0.05 nM (EGFR), IC50=3 nM (EGFR), 22 nM (T790M/L858R).</p>Fórmula:C25H26N6O2Pureza:99.67%Cor e Forma:SolidPeso molecular:442.51Theliatinib tartrate
CAS:<p>Theliatinib: oral EGFR blocker, Ki 0.05 nM, IC50 3 nM (wild-type), 22 nM (T790M/L858R), >50x kinase selectivity.</p>Fórmula:C29H32N6O8Cor e Forma:SolidPeso molecular:592.6Decernotinib
CAS:<p>Decernotinib (VRT-831509)(VX-509; VRT-831509) is a potent and selective Janus kinase 3 (JAK3) inhibitor with Ki of 2.5 nM; IC50 is 50-170 nM in cellular assays.</p>Fórmula:C18H19F3N6OPureza:99.28% - >99.99%Cor e Forma:SolidPeso molecular:392.38RepSox
CAS:<p>RepSox (ALK5 Inhibitor II) is a TGFβR-1/ALK5 inhibitor that selectively inhibits the binding of ATP to ALK5 and the autophosphorylation of ALK5 (IC50=23/4 nM).</p>Fórmula:C17H13N5Pureza:98.8% - 99.73%Cor e Forma:SolidPeso molecular:287.32LDN-214117
CAS:<p>LDN-214117 is a potent and selective ALK2 inhibitor.</p>Fórmula:C25H29N3O3Pureza:98% - 99.82%Cor e Forma:SolidPeso molecular:419.52SU5205
CAS:<p>SU5205 is a VEGFR2 inhibitor.</p>Fórmula:C15H10FNOPureza:99.62% - 99.67%Cor e Forma:SolidPeso molecular:239.24R112
CAS:<p>R112 ((E)-Elafibranor) is an ATP-competitive inhibitor of Syk kinase.</p>Fórmula:C16H13FN4O2Pureza:99.27% - 99.84%Cor e Forma:SolidPeso molecular:312.3TL-895
CAS:<p>TL-895 is a potent, selective ATP-competitive BTK inhibitor (IC50 = 1.5 nM, Ki = 11.9 nM).</p>Fórmula:C25H26FN5O2Pureza:99.96%Cor e Forma:SolidPeso molecular:447.5NRC-2694
CAS:<p>NRC-2694 is an antagonist of the epidermal growth factor receptor (EGFR). It has anti-cancer and anti-proliferative properties.</p>Fórmula:C24H26N4O3Pureza:99.90%Cor e Forma:SolidPeso molecular:418.49SYR127063
CAS:<p>SYR127063 (BDBM-92454) (BDBM92454) is a potent and selective HER2 inhibitor, binds to HER2 in a reactive conformation.</p>Fórmula:C23H20ClF3N4O3Pureza:98.57%Cor e Forma:SolidPeso molecular:492.88SCR-1481B1
CAS:<p>SCR-1481B1 (c-Met inhibitor 2) has activity against cancers dependent on Met activation and also has activity against cancers as a VEGFR inhibitor</p>Fórmula:C32H40ClF2N6O13PPureza:98.07%Cor e Forma:SolidPeso molecular:821.12Ponatinib
CAS:<p>Ponatinib (AP24534) is an orally available, multitargeted kinase inhibitor (IC50s: 0.37/1.1/1.5/2.2/5.4 nM for Abl, PDGFRα, VEGFR2, FGFR1, and Src, respectively</p>Fórmula:C29H27F3N6OPureza:98% - 99.60%Cor e Forma:SolidPeso molecular:532.56Dacomitinib
CAS:<p>Dacomitinib (PF299) is an oral selective inhibitor of EGFR, ERBB2, ERBB4 with IC50s: 6, 45.7, 73.7 nM.</p>Fórmula:C24H25ClFN5O2Pureza:99.4% - 99.72%Cor e Forma:SolidPeso molecular:469.94Oritinib mesylate
CAS:<p>Oritinib mesylate (SH-1028), an oral pyrimidine EGFR blocker with 18 nM IC50, targets both sensitive and T790M resistant mutations.</p>Fórmula:C32H41N7O5SCor e Forma:SolidPeso molecular:635.78Pralsetinib
CAS:<p>Pralsetinib (Blu667) (BLU-667) is a highly potent, selective RET inhibitor (IC50s: 0.4, 0.3, 0.4, 0.4, and 0.4 nM for WT RET, RET mutants V804L, V804M, M918T</p>Fórmula:C27H32FN9O2Pureza:97.88% - 99.8%Cor e Forma:SolidPeso molecular:533.6AMG-47a
CAS:<p>AMG-47a inhibits Lck, T cell growth, and degrades KRAS oncoprotein, affecting EGFP-KRASG12V but not EGFP.</p>Fórmula:C29H28F3N5O2Pureza:98%Cor e Forma:SolidPeso molecular:535.56Remibrutinib
CAS:<p>Remibrutinib inhibits BTK activity with an IC50 value of 0.023 μM in blood.</p>Fórmula:C27H27F2N5O3Pureza:99.5% - 99.81%Cor e Forma:SolidPeso molecular:507.53LDC1267
CAS:<p>LDC1267 is a excellently specific TAM(Tyro3, Axl and Mer) kinase inhibitor, for Mer( IC50<5 nM), Tyro3(IC50=8 nM), and Axl(IC50=29 nM).</p>Fórmula:C30H26F2N4O5Pureza:99.38% - 99.88%Cor e Forma:SolidPeso molecular:560.55Vatalanib free base
CAS:<p>Vatalanib is a VEGFR2/KDR inhibitor (IC50: 37 nM).</p>Fórmula:C20H15ClN4Pureza:99.52%Cor e Forma:SolidPeso molecular:346.81ZM 306416
CAS:<p>ZM 306416 (CB 676475), a VEGFR1 inhibitor (IC50: 0.33 μM), can also inhibit EGFR (IC50<10 nM).</p>Fórmula:C16H13ClFN3O2Pureza:99.37% - ≥95%Cor e Forma:SolidPeso molecular:333.74Crenolanib
CAS:<p>Crenolanib (ARO 002) is an orally bioavailable type III tyrosine kinases inhibitor of PDGFRα/β and FLT3 (IC50s: 11, 3.2, and 4 nM).</p>Fórmula:C26H29N5O2Pureza:98.40% - 99.73%Cor e Forma:SolidPeso molecular:443.54AG490
CAS:<p>AG490 inhibits EGFR (0.1 μM IC50), 135x > selective than ErbB2, blocks JAK2, spares Lyn, Lck, Syk, Btk, Src.</p>Fórmula:C17H14N2O3Pureza:98.6% - 99.39%Cor e Forma:Yellow SolidPeso molecular:294.31-Naphthyl PP1
CAS:<p>1-Naphthyl PP1 (1-NA-PP 1) is a selective src inhibitor(v-Src and c-Fyn, c-Abl, CDK2 and CAMK II with IC50s of 1.0, 0.6, 0.6, 18 and 22 μM, respectively)</p>Fórmula:C19H19N5Pureza:99.85%Cor e Forma:White Cyrstalline SolidPeso molecular:317.39Tolimidone
CAS:<p>Tolimidone (NSC 314335) is a chemical compound which inhibits acid secretion in animal models and also acts as a bronchodilator in histamine-challenged animals.</p>Fórmula:C11H10N2O2Pureza:99.85% - 99.85%Cor e Forma:SolidPeso molecular:202.21Butein
CAS:<p>Butein is a cAMP-specific PDE inhibitor, protein tyrosine kinase inhibitor, and SIRT1 activator.Cost-effective and quality-assured.</p>Fórmula:C15H12O5Pureza:98.76% - >99.99%Cor e Forma:SolidPeso molecular:272.25Pexmetinib
CAS:<p>Pexmetinib (ARRY-614) is an orally bioavailable dual p38 MAPK/Tie-2 inhibitor.Cost-effective and quality-assured.</p>Fórmula:C31H33FN6O3Pureza:99.07% - 99.66%Cor e Forma:SolidPeso molecular:556.63Entospletinib
CAS:<p>Entospletinib (GS-9973) is a Syk inhibitor (IC50=7.7 nM) with selective, oral activity. High-Quality, Low-Cost!</p>Fórmula:C23H21N7OPureza:98.54% - 99.51%Cor e Forma:SolidPeso molecular:411.46Fisogatinib
CAS:<p>Fisogatinib (BLU-554) is a highly potent, selective, and orally active FGFR4 inhibitor.Cost-effective and quality-assured.</p>Fórmula:C24H24Cl2N4O4Pureza:99.27% - ≥95%Cor e Forma:SolidPeso molecular:503.38Chrysophanol
CAS:<p>Chrysophanol (Turkey Rhubarb) is an EGFR/mTOR pathway inhibitor, which can be found in rhubarb, and sorrel.</p>Fórmula:C15H10O4Pureza:99.44% - 99.91%Cor e Forma:Physical Description Golden Yellow Plates Or Brown Powder Melting Point 196°CPeso molecular:254.24DMH-1
CAS:<p>DMH-1 is a BMP inhibitor that inhibits ALK1, ALK2, ALK3 and ALK6. DMH-1 promotes pluripotent stem cell differentiation. Cost-effective and quality-assured.</p>Fórmula:C24H20N4OPureza:98% - 99.92%Cor e Forma:SolidPeso molecular:380.44Pyridostatin TFA
CAS:<p>Pyridostatin Trifluoroacetate Salt is a G-quadruplexe stabilizer with Kd of 490 nM in a cell-free assay, which targets a series of proto-oncogenes including c-</p>Fórmula:C37H35F9N8O11Pureza:97.09% - 99.84%Cor e Forma:SolidPeso molecular:938.71CH5424802 analog
CAS:<p>CH5424802 analog is a selective ALK inhibitor capable of blocking the resistant gatekeeper mutant.</p>Fórmula:C28H30N4O2Pureza:98.96%Cor e Forma:SolidPeso molecular:454.56
