Tirosina Quinase/Adaptador
Os inibidores de tirosina quinase e adaptadores são compostos que têm como alvo as tirosina quinases e suas proteínas adaptadoras associadas, que desempenham papéis fundamentais na sinalização celular, crescimento e diferenciação. Esses inibidores são ferramentas essenciais na pesquisa sobre o câncer, pois muitas tirosina quinases estão envolvidas nas vias de sinalização que impulsionam o crescimento e a metástase dos tumores. Ao inibir as tirosina quinases, esses compostos podem bloquear cascatas de sinalização críticas, oferecendo potenciais estratégias terapêuticas para vários tipos de câncer e outras doenças que envolvem sinalização celular anormal. Na CymitQuimica, oferecemos uma ampla gama de inibidores de tirosina quinase e adaptadores de alta qualidade para apoiar sua pesquisa em oncologia, biologia molecular e desenvolvimento de terapias direcionadas.
Subcategorias de "Tirosina Quinase/Adaptador"
- ALK(112 produtos)
- CSF-1R(42 produtos)
- EGFR(572 produtos)
- Receptor de Efrina(23 produtos)
- FLT(92 produtos)
- Receptor do Factor de Crescimento Fibroblasto (FGFR)(169 produtos)
- HER(5 produtos)
- Hck(3 produtos)
- IGF-1R(87 produtos)
- PDGFR(126 produtos)
- PYK2(7 produtos)
- Src(79 produtos)
- Receptor TAM(32 produtos)
- Tie-2(20 produtos)
- Receptor TrK(59 produtos)
- Tirosina Quinases(26 produtos)
- VEGFR(268 produtos)
- c-Fms(108 produtos)
- c-Kit(101 produtos)
- c-Met/HGFR(128 produtos)
- c-RET(51 produtos)
Exibir 13 mais subcategorias
Foram encontrados 1372 produtos de "Tirosina Quinase/Adaptador"
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K02288
CAS:<p>K 02288 is a novel small molecule inhibitor of ALK1/2/3/6.</p>Fórmula:C20H20N2O4Pureza:98% - 99.83%Cor e Forma:SolidPeso molecular:352.38BMS-794833
CAS:<p>BMS-794833 is a potent ATP competitive inhibitor of Met/VEGFR2; a prodrug of BMS-817378.</p>Fórmula:C23H15ClF2N4O3Pureza:98% - 99.69%Cor e Forma:SolidPeso molecular:468.84PD168393
CAS:<p>PD168393 is an irreversible EGFR inhibitor (IC50: 0.70 nM), irreversibly alkylate Cys-773; inactive against PKC, FGFR, PDGFR, and insulin.</p>Fórmula:C17H13BrN4OPureza:99.13% - 99.83%Cor e Forma:SolidPeso molecular:369.22NS309
CAS:<p>NS309 activates SK/KCa2, IK/KCa3.1 (0.12-1.2 μM EC50, 10-90 nM EC50), and Kv11.1 channels; doesn't affect BK/KCa1.1; modulates neuronal firing.</p>Fórmula:C8H4Cl2N2O2Pureza:97.55%Cor e Forma:SolidPeso molecular:231.04SAR131675
CAS:<p>SAR131675 is a potent and selective VEGFR3 inhibitor with an IC50 of 23 nM.</p>Fórmula:C18H22N4O4Pureza:99.74%Cor e Forma:SolidPeso molecular:358.39Cetuximab
CAS:<p>Cetuximab (C225) is a monoclonal antibody that is an inhibitor of human epidermal growth factor receptor (EGFR) (Kd=0.201 nM).</p>Fórmula:C107H179N35O36S7Pureza:95 - 98.60%Cor e Forma:LiquidPeso molecular:152 kDaLenvatinib mesylate
CAS:<p>Lenvatinib mesylate (E7080 (mesylate)) is an oral and multi-targeted inhibitor of VEGFR1-3, FGFR1-4, PDGFR, KIT, and RET, with potent antitumor activities.</p>Fórmula:C22H23ClN4O7SPureza:99.03% - 99.79%Cor e Forma:SolidPeso molecular:522.96Pacritinib
CAS:<p>Pacritinib (SB1518) (SB1518) is an effective and specific inhibitor of JAK2 and FLT3 (IC50: 23/22 nM, in cell-free assays).</p>Fórmula:C28H32N4O3Pureza:99.25% - 99.49%Cor e Forma:SolidPeso molecular:472.58Baricitinib phosphate
CAS:<p>Baricitinib phosphate (INCB028050) is a selective orally bioavailable JAK1/JAK2 inhibitor.</p>Fórmula:C16H20N7O6PSPureza:99.4% - 99.82%Cor e Forma:SolidPeso molecular:469.41Tie2 kinase inhibitor 1
CAS:<p>Tie2 kinase inhibitor 1 (Tie2 kinase inhibitor), an optimized compound of SB-203580, is selective to Tie2 with IC50 of 0.25 μM, which is 200-fold more effective</p>Fórmula:C26H21N3O2SPureza:99.51%Cor e Forma:SolidPeso molecular:439.53SSR128129E
CAS:<p>SSR128129E (SSR) is an allosteric and orally-active FGFR1 inhibitor (IC50: 1.9 μM), but not affecting other related RTKs.</p>Fórmula:C18H15N2O4·NaPureza:98.79% - ≥95%Cor e Forma:SolidPeso molecular:346.31ONO-7475
CAS:<p>ONO-7475 is an inhibitor with high specificity for anexelekto and MER tyrosine kinase</p>Fórmula:C32H26N4O6Pureza:98.74%Cor e Forma:SolidPeso molecular:562.57GW788388
CAS:<p>GW788388 is a potent and selective inhibitor of ALK5, also inhibits TGF-(beta) type II receptor and activin type II receptor activities.</p>Fórmula:C25H23N5O2Pureza:98.03% - 99.58%Cor e Forma:SolidPeso molecular:425.48PKI (5-24) Acetate(99534-03-9 free base)
<p>PKI (5-24) Acetate is a high affinity PKA inhibitor (Ki = 2.3 nM).</p>Fórmula:C96H152N32O33Pureza:99.47%Cor e Forma:SolidPeso molecular:2282.43AG1557
CAS:<p>AG1557 (AG-1557) is an inhibitor of the epidermal growth factor receptor (EGFR) tyrosine kinase (pIC50: 8.194).</p>Fórmula:C16H14IN3O2Pureza:98.61% - 99.23%Cor e Forma:SolidPeso molecular:407.21XL092
CAS:<p>XL092 (JUN04542) is an Axl Mer cMet KDR inhibitor for the treatment of Axl and Mer receptor tyrosine kinase- dependent disorders.</p>Fórmula:C29H25FN4O5Pureza:98.60%Cor e Forma:SolidPeso molecular:528.53ML347
CAS:<p>ML347 (LDN 193719)(DN193719) is a highly specific ALK1/2 inhibitor ( IC50: 46/32 nM), and the selectivity for ALK2 is >300-fold than ALK3.</p>Fórmula:C22H16N4OPureza:99.30% - ≥95%Cor e Forma:SolidPeso molecular:352.39E-4031 dihydrochloride
CAS:<p>E-4031 is a methanesulfonanilide class III antiarrhythmic agent that prolongs cardiac action potential duration by blocking ERG K+ channels (IC50 = 29 nM)</p>Fórmula:C21H29Cl2N3O3SPureza:99.31% - 99.87%Cor e Forma:SolidPeso molecular:474.44H3B-6527
CAS:<p>H3B-6527 Is a Potent and Selective Inhibitor of FGFR4 in FGF19-Driven Hepatocellular Carcinoma, with antineoplastic activity.</p>Fórmula:C29H34Cl2N8O4Pureza:97.45%Cor e Forma:SolidPeso molecular:629.54TX1-85-1
CAS:<p>TX1-85-1: irreversible Her3 inhibitor (IC50: 23 nM), degrades Her3 protein, disrupts signaling, binds Cys721 covalently.</p>Fórmula:C32H36N8O3Pureza:98.12% - 98.12%Cor e Forma:SolidPeso molecular:580.68TAS0728
CAS:<p>TAS0728 is a HER2 inhibitor, with antitumor activity</p>Fórmula:C26H32N8O3Pureza:97.78%Cor e Forma:SolidPeso molecular:504.58Pyridostatin
CAS:<p>Pyridostatin (RR82) is a synthetic small-molecule stabilizer of G-quadruplexes, a secondary structure of DNA that usually exists in the end of the chromosome or</p>Fórmula:C31H32N8O5Pureza:98%Cor e Forma:SolidPeso molecular:596.64LM22A-4
CAS:<p>LM22A-4: BDNF mimetic, TrkB agonist, IC50=47 nM (fluorescence anisotropy).</p>Fórmula:C15H21N3O6Pureza:99.56%Cor e Forma:SolidPeso molecular:339.34WRG-28
CAS:<p>WRG-28 is a potent and selective, allosteric discoidin domain receptor 2 (ddr2) inhibitor(IC50 : 230 nM)</p>Fórmula:C21H18N2O5SPureza:97.21%Cor e Forma:SolidPeso molecular:410.44AD80
CAS:<p>AD80, a multikinase inhibitor, inhibits RET, RAF, SRCand S6K, with greatly reduced mTOR activity.</p>Fórmula:C22H19F4N7OPureza:99.49% - 99.75%Cor e Forma:SolidPeso molecular:473.43Tyrphostin B44, (+) enantiomer
CAS:<p>Tyrphostin B44, (+) enantiomer is an inhibitor of epidermal growth factor receptor (EGFR) kinase with IC50 of 0.86 μM and has less active than the (-)</p>Fórmula:C18H16N2O3Pureza:97.18%Cor e Forma:SolidPeso molecular:308.33Tolimidone
CAS:<p>Tolimidone (NSC 314335) is a chemical compound which inhibits acid secretion in animal models and also acts as a bronchodilator in histamine-challenged animals.</p>Fórmula:C11H10N2O2Pureza:99.85% - 99.85%Cor e Forma:SolidPeso molecular:202.21NRC-2694
CAS:<p>NRC-2694 is an antagonist of the epidermal growth factor receptor (EGFR). It has anti-cancer and anti-proliferative properties.</p>Fórmula:C24H26N4O3Pureza:99.90%Cor e Forma:SolidPeso molecular:418.49R112
CAS:<p>R112 ((E)-Elafibranor) is an ATP-competitive inhibitor of Syk kinase.</p>Fórmula:C16H13FN4O2Pureza:99.27% - 99.84%Cor e Forma:SolidPeso molecular:312.3RepSox
CAS:<p>RepSox (ALK5 Inhibitor II) is a TGFβR-1/ALK5 inhibitor that selectively inhibits the binding of ATP to ALK5 and the autophosphorylation of ALK5 (IC50=23/4 nM).</p>Fórmula:C17H13N5Pureza:98.8% - 99.73%Cor e Forma:SolidPeso molecular:287.32Theliatinib
CAS:<p>Theliatinib: potent, selective EGFR inhibitor, anti-tumor; Ki=0.05 nM (EGFR), IC50=3 nM (EGFR), 22 nM (T790M/L858R).</p>Fórmula:C25H26N6O2Pureza:99.67%Cor e Forma:SolidPeso molecular:442.51Entrectinib
CAS:<p>Entrectinib (RXDX-101) is an orally Trk, ROS1, and ALK inhibitor. Entrectinib exhibits antitumor activity. Cost-effective and quality-assured.</p>Fórmula:C31H34F2N6O2Pureza:98.03% - 99.61%Cor e Forma:SolidPeso molecular:560.64(E)-AG 99
CAS:<p>(E)-AG 99 ((E)-Tyrphostin AG 99) is an inhibitor of EGFR kinase (IC50: 10 μM in the human epidermoid carcinoma cell line A431).</p>Fórmula:C10H8N2O3Pureza:99.23%Cor e Forma:SolidPeso molecular:204.185'-Fluoroindirubinoxime
CAS:<p>5'-Fluoroindirubinoxime (5'-FIO) is a potent FLT3 inhibitor( IC50 : 15 nM).</p>Fórmula:C16H10FN3O2Pureza:>99.99%Cor e Forma:SolidPeso molecular:295.27JCN037
CAS:<p>JCN037 is potent, non-covalent and brain-penetrant inhibitor of EGFR(EGFR, p-wtEGFR and pEGFRvⅢ with IC50 of 2.49 nM, 3.95 nM, 4.48 nM , respectively).</p>Fórmula:C16H11BrFN3O2Pureza:99.5%Cor e Forma:SolidPeso molecular:376.18Fostamatinib Disodium
CAS:<p>Fostamatinib Disodium (R788 Disodium) is an orally available Syk kinase inhibitor with potential anti-inflammatory and immunomodulating activities.</p>Fórmula:C23H24FN6O9P·2NaPureza:96.13% - 99.09%Cor e Forma:SolidPeso molecular:624.42FLT3-IN-2
CAS:<p>FLT3-IN-2 is an FLT3 inhibitor (IC50<1 μM).</p>Fórmula:C21H16ClF3N4Pureza:97.57% - 98.53%Cor e Forma:SolidPeso molecular:416.83ASP5878
CAS:<p>ASP5878 potently inhibited the tyrosine kinase activities of recombinant FGFR1, 2, 3, and 4 with IC50 values of 0.47, 0.60, 0.74, and 3.5 nmol/L.</p>Fórmula:C18H19F2N5O4Pureza:99.8% - 99.89%Cor e Forma:SolidPeso molecular:407.37Bacitracin Zinc
CAS:<p>Bacitracin Zinc is a dephosphorylated disruptor of C55-isoprene pyrophosphate that inhibits Tyr cleavage in Met-enkephalin with an IC50 of 10 μM.</p>Fórmula:C66H101N17O16SZnPureza:63.98%Cor e Forma:Light-Colored Free-Flowing PowdersPeso molecular:1486.07Naquotinib
CAS:<p>Naquotinib (ASP8273) (ASP8273) is an orally available, mutant-selective and irreversible EGFR inhibitor; (IC50s: 8-33 nM and 230 nM toward EGFR mutants and EGFR</p>Fórmula:C30H42N8O3Pureza:97.49%Cor e Forma:SolidPeso molecular:562.71Futibatinib
CAS:<p>Futibatinib (TAS-120) is an orally active, potent,and irreversible FGFR inhibitor of FGFR1, FGFR2, FGFR3, and FGFR4.Cost-effective and quality-assured.</p>Fórmula:C22H22N6O3Pureza:97.66% - 99.44%Cor e Forma:SolidPeso molecular:418.45Gilteritinib
CAS:<p>Gilteritinib (ASP2215) is a potent inhibitor at the FMS-related tyrosine kinase 3 (FLT3) and AXL tyrosine kinase receptors (IC50 = 0.29 nM and <1 nM,</p>Fórmula:C29H44N8O3Pureza:97.75% - 99.90%Cor e Forma:SolidPeso molecular:552.71PP1
CAS:<p>PP1 (AGL 1872), a specific and effective Src inhibitor, is with IC50 for Lck/Fyn is 5 nM/ 6 nM, respectively.</p>Fórmula:C16H19N5Pureza:99% - 99.88%Cor e Forma:Off-White To Grey SolidPeso molecular:281.36WH-4-023
CAS:<p>WH-4-023 (Dual LCK/SRC inhibitor) is a potent and orally active Lck/Src inhibitor. It also potently inhibits SIK.</p>Fórmula:C32H36N6O4Pureza:98% - 99.75%Cor e Forma:SolidPeso molecular:568.67Cyclotraxin B acetate(1203586-72-4 free base)
<p>Cyclotraxin B acetate is an antagonist of TrkB receptors; inhibits BDNF-induced TrkB activity (IC50 = 0.30 nM).</p>Fórmula:C50H77N13O19S3Pureza:99.42%Cor e Forma:SolidPeso molecular:1260.42AZD4547
CAS:<p>AZD4547 is an FGFR family inhibitor, and is able to act on FGFR1, FGFR2, FGFR3 and FGFR4. IC50:165 nM).Cost-effective and quality-assured.</p>Fórmula:C26H33N5O3Pureza:99.37% - 99.88%Cor e Forma:SolidPeso molecular:463.57SM 16
CAS:<p>SM 16 is a ALK5/ALK4 kinase inhibitor (Ki: 10/1.5 nM).</p>Fórmula:C25H26N4O3Pureza:99.72%Cor e Forma:SolidPeso molecular:430.5Lorlatinib
CAS:<p>Lorlatinib (PF-6463922) is an orally available, ATP-competitive inhibitor of the receptor tyrosine kinases, anaplastic lymphoma kinase (ALK) and C-ros oncogene</p>Fórmula:C21H19FN6O2Pureza:99.77% - 99.95%Cor e Forma:SolidPeso molecular:406.41Endoxifen (Z-isomer)
CAS:<p>Endoxifen Z-isomer (EDX) is a key active metabolite of tamoxifen with higher affinity and specificity to estrogen receptors that inhibits aromatase activity.</p>Fórmula:C25H27NO2Pureza:99.19% - 99.81%Cor e Forma:SolidPeso molecular:373.49PF-04217903
CAS:<p>MET Tyrosine Kinase Inhibitor PF-04217903 is an orally bioavailabe, small-molecule tyrosine kinase inhibitor with potential antineoplastic activity.</p>Fórmula:C19H16N8OPureza:98.41% - 98.55%Cor e Forma:SolidPeso molecular:372.381-NM-PP1
CAS:<p>1-NM-PP1 (PP1 Analog II) is a cell-permeable PP1 analog that acts as a potent and selective inhibitor of mutant kinases over their wild-type progenitors.</p>Fórmula:C20H21N5Pureza:98% - 98.93%Cor e Forma:White Cyrstalline SolidPeso molecular:331.41SAR125884 hydrochlorid (1116743-46-4(free base))
CAS:<p>SAR125844 is a potent and selective MET kinase inhibitor with a favorable preclinical toxicity profile,(IC50=4.2 nM).</p>Fórmula:C25H23FN8O2S2·HClPureza:97.95%Cor e Forma:SolidPeso molecular:587AEE788
CAS:<p>AEE788 (NVP-AEE 788) has been used in trials studying the treatment of Cancer, Glioblastoma Multiforme, and Brain and Central Nervous System Tumors.</p>Fórmula:C27H32N6Pureza:98% - >99.99%Cor e Forma:SolidPeso molecular:440.58Trastuzumab
CAS:<p>Trastuzumab is a humanized monoclonal antibody for patients with invasive breast cancers that overexpress HER2.</p>Pureza:98% - SDS-PAGE: 97.1%；SEC-HPLC: 99.2%Cor e Forma:LiquidPeso molecular:Approximately 145.53 kDaPKI-166 hydrochloride
CAS:<p>EGFR-kinase inhibitor, IC50 0.7 nM, >3000x selective, cuts metastasis and angiogenesis in mice, antihypertensive, oral use.</p>Fórmula:C20H19ClN4OCor e Forma:SolidPeso molecular:366.85JNJ-38877605
CAS:<p>JNJ-38877605 is an ATP-competitive c-Met inhibitor (IC50: 4 nM), 600-fold selective for c-Met than 200 other tyrosine and serine-threonine kinases.</p>Fórmula:C19H13F2N7Pureza:97.04% - 98.27%Cor e Forma:SolidPeso molecular:377.35TAK-593
CAS:<p>TAK-593 is an effective VEGFR and PDGFR family inhibitor (IC50s: 3.2, 0.95, 1.1, 4.3, and 13 nM for VEGFR1, VEGFR2, VEGFR3, PDFGRα, and PDFGRβ, respectively).</p>Fórmula:C23H23N7O3Pureza:99.37%Cor e Forma:SolidPeso molecular:445.47Masitinib mesylate
CAS:<p>Masitinib mesylate (AB-1010 mesylate) is a selective and orally bioavailable c-Kit inhibitor (IC50 of 200 nM,540/800 nM,510 nM for human recombinant c-Kit;</p>Fórmula:C29H34N6O4S2Pureza:97.67% - 98.44%Cor e Forma:SolidPeso molecular:594.75Sulforaphene
CAS:<p>Sulforaphene, from radish seeds, aids cancer cell apoptosis and inhibits migration; has an ED50 for velvetleaf at ~2x10^-4 M.</p>Fórmula:C6H9NOS2Pureza:97.55% - 99.19%Cor e Forma:Slightly Yellowish LiquidPeso molecular:175.27KX1-004
CAS:<p>KX1-004, a potential protective drug for NIHL, is an effective small molecule inhibitor of Src-PTK.</p>Fórmula:C16H13FN2O2Pureza:99.39% - ≥95%Cor e Forma:SolidPeso molecular:284.29Branebrutinib
CAS:<p>Branebrutinib (BMS986195) is a potent, covalent inhibitor of Bruton's tyrosine kinase (BTK), >5,000-fold selective over all kinases outside of the Tec family.</p>Fórmula:C20H23FN4O2Pureza:95.86% - 99.31%Cor e Forma:SolidPeso molecular:370.42Acalabrutinib
CAS:<p>Acalabrutinib (ACP-196), also known as ACP-196, is an orally available inhibitor of Bruton's tyrosine kinase (BTK) with potential antineoplastic activity.</p>Fórmula:C26H23N7O2Pureza:98.94% - 99.64%Cor e Forma:SolidPeso molecular:465.51SU 4313
CAS:SU 4313 is a bioactive chemical.Fórmula:C18H17NOPureza:99.51% - 99.89%Cor e Forma:SolidPeso molecular:263.33ISCK03
CAS:<p>ISCK03 is a selective SCF/c-Kit inhibitor.</p>Fórmula:C19H21N3O2SPureza:98.39%Cor e Forma:SolidPeso molecular:355.45Tyrphostin A1
CAS:<p>Tyrphostin A1 (Tyrphostin 1) is an inhibitor of EGFR tyrosine kinase .</p>Fórmula:C11H8N2OPureza:98.32%Cor e Forma:SolidPeso molecular:184.19WZ4002
CAS:<p>WZ4002 is a mutant-selective EGFR inhibitor for EGFR(L858R) and EGFR(T790M) with IC50 of 2 nM/8 nM.</p>Fórmula:C25H27ClN6O3Pureza:97.51%Cor e Forma:SolidPeso molecular:494.97Epitinib
CAS:<p>Epitinib is an orally active, selective, blood-brain barrier crossing epidermal growth factor receptor tyrosine kinase inhibitor (EGFR-TKI).</p>Fórmula:C24H26N6O2Cor e Forma:SolidPeso molecular:430.5PP121
CAS:<p>PP-121 inhibits PDGFR, Hck, mTOR, VEGFR2, Src, Abl, and DNA-PK with IC50 values ranging from 2 to 60 nM.</p>Fórmula:C17H17N7Pureza:98.45% - 99.67%Cor e Forma:SolidPeso molecular:319.36AZ304
CAS:<p>AZ304 is an ATP-competitive dual BRAF kinase inhibitor, potently inhibits BRAF (WT), BRAF (V600E), and wild type CRAF (IC50s: 79/38/68 nM).</p>Fórmula:C27H25N5O2Pureza:99.82%Cor e Forma:SolidPeso molecular:451.52Gefitinib-based PROTAC 3
CAS:<p>Gefitinib-PROTAC 3 degrades EGFR in cancer cells; DC50s: 11.7 nM (HCC827) and 22.3 nM (H3255).</p>Fórmula:C47H57ClFN7O8SPureza:97.29% - 98.25%Cor e Forma:SolidPeso molecular:934.51Derazantinib dihydrochloride
CAS:<p>Derazantinib, a multi-kinase inhibitor targeting FGFR, benefits FGFR2-positive iCCA; its dihydrochloride form is a salt variant.</p>Fórmula:C29H31Cl2FN4OCor e Forma:SolidPeso molecular:541.49Almonertinib
CAS:<p>Almonertinib (HS-10296) is an inhibitor of EGFR activation mutation and tolerant mutation of EGFR T790M, which has only limited activity against wild-type EGFR.</p>Fórmula:C30H35N7O2Pureza:99.99%Cor e Forma:SolidPeso molecular:525.64Merestinib
CAS:<p>Merestinib (LY2801653) is an orally available, small molecule inhibitor of the proto-oncogene c-Met (Ki: 2 nM) with potential antineoplastic activity.</p>Fórmula:C30H22F2N6O3Pureza:95% - 99.71%Cor e Forma:SolidPeso molecular:552.53Sotuletinib
CAS:<p>Sotuletinib (BLZ945) is an orally active, effective and specific CSF-1R inhibitor, >1000-fold selective against its closest receptor tyrosine kinase homologs.</p>Fórmula:C20H22N4O3SPureza:97.43% - 99.82%Cor e Forma:SolidPeso molecular:398.48SU5408
CAS:<p>SU5408 (VEGFR2 Kinase Inhibitor I) is a potent, cell-permeable inhibitor of the VEGFR2 kinase.</p>Fórmula:C18H18N2O3Pureza:99.35%Cor e Forma:SolidPeso molecular:310.35Linsitinib
CAS:<p>OSI-906 (Linsitinib) is an oral inhibitor of IGF-1R with anti-cancer properties, potentially halting tumor growth and inducing cell death.</p>Fórmula:C26H23N5OPureza:99.71% - ≥95%Cor e Forma:SolidPeso molecular:421.49CH5424802 analog
CAS:<p>CH5424802 analog is a selective ALK inhibitor capable of blocking the resistant gatekeeper mutant.</p>Fórmula:C28H30N4O2Pureza:98.96%Cor e Forma:SolidPeso molecular:454.56DMH-1
CAS:<p>DMH-1 is a BMP inhibitor that inhibits ALK1, ALK2, ALK3 and ALK6. DMH-1 promotes pluripotent stem cell differentiation. Cost-effective and quality-assured.</p>Fórmula:C24H20N4OPureza:98% - 99.92%Cor e Forma:SolidPeso molecular:380.44Entospletinib
CAS:<p>Entospletinib (GS-9973) is a Syk inhibitor (IC50=7.7 nM) with selective, oral activity. High-Quality, Low-Cost!</p>Fórmula:C23H21N7OPureza:98.54% - 99.51%Cor e Forma:SolidPeso molecular:411.46Pexmetinib
CAS:<p>Pexmetinib (ARRY-614) is an orally bioavailable dual p38 MAPK/Tie-2 inhibitor.Cost-effective and quality-assured.</p>Fórmula:C31H33FN6O3Pureza:99.07% - 99.66%Cor e Forma:SolidPeso molecular:556.63ZM 306416
CAS:<p>ZM 306416 (CB 676475), a VEGFR1 inhibitor (IC50: 0.33 μM), can also inhibit EGFR (IC50<10 nM).</p>Fórmula:C16H13ClFN3O2Pureza:99.37% - ≥95%Cor e Forma:SolidPeso molecular:333.74Vatalanib free base
CAS:<p>Vatalanib is a VEGFR2/KDR inhibitor (IC50: 37 nM).</p>Fórmula:C20H15ClN4Pureza:99.52%Cor e Forma:SolidPeso molecular:346.81AMG-47a
CAS:<p>AMG-47a inhibits Lck, T cell growth, and degrades KRAS oncoprotein, affecting EGFP-KRASG12V but not EGFP.</p>Fórmula:C29H28F3N5O2Pureza:98%Cor e Forma:SolidPeso molecular:535.56Oritinib mesylate
CAS:<p>Oritinib mesylate (SH-1028), an oral pyrimidine EGFR blocker with 18 nM IC50, targets both sensitive and T790M resistant mutations.</p>Fórmula:C32H41N7O5SCor e Forma:SolidPeso molecular:635.78Decernotinib
CAS:<p>Decernotinib (VRT-831509)(VX-509; VRT-831509) is a potent and selective Janus kinase 3 (JAK3) inhibitor with Ki of 2.5 nM; IC50 is 50-170 nM in cellular assays.</p>Fórmula:C18H19F3N6OPureza:99.28% - >99.99%Cor e Forma:SolidPeso molecular:392.38Theliatinib tartrate
CAS:<p>Theliatinib: oral EGFR blocker, Ki 0.05 nM, IC50 3 nM (wild-type), 22 nM (T790M/L858R), >50x kinase selectivity.</p>Fórmula:C29H32N6O8Cor e Forma:SolidPeso molecular:592.6G5-7
CAS:<p>G5-7 is an oral JAK2 inhibitor targeting EGFR/STAT3 phosphorylation with potential for glioma research.</p>Fórmula:C22H19F2NO3Pureza:97.3%Cor e Forma:SolidPeso molecular:383.39AG-494
CAS:<p>AG-494 (Tyrphostin B48) is an inhibitor of epidermal growth factor receptor kinase.</p>Fórmula:C16H12N2O3Pureza:98.69%Cor e Forma:SolidPeso molecular:280.28(E/Z)-Zotiraciclib
CAS:<p>(E/Z)-Zotiraciclib ((E/Z)-TG02) inhibits CDK2, JAK2, and FLT3 effectively with IC50s of 13, 73, and 56 nM, respectively.</p>Fórmula:C23H24N4OPureza:97.75% - 99.92%Cor e Forma:SolidPeso molecular:372.46Neratinib
CAS:<p>Neratinib (HKI-272) (HKI-272) is an orally available, irreversible tyrosine kinase inhibitor for HER2 and EGFR (IC50: 59/92 nM), respectively.</p>Fórmula:C30H29ClN6O3Pureza:96.17% - 99.85%Cor e Forma:SolidPeso molecular:557.04Osimertinib mesylate
CAS:<p>Osimertinib mesylate (AZD-9291 mesylate) is an EGFR third-generation inhibitor. Osimertinib mesylate has antitumor activity. Cost-effective and quality-assured.</p>Fórmula:C29H37N7O5SPureza:99.46% - >99.99%Cor e Forma:SolidPeso molecular:595.71PF-6274484
CAS:<p>PF-6274484 is an EGFR inhibitor with Ki values of 0.14 and 0.18 nM for EGFR-L858R/T790M and WT-EGFR, respectively.</p>Fórmula:C18H14ClFN4O2Pureza:97.71%Cor e Forma:SolidPeso molecular:372.78RG13022
CAS:<p>RG13022 (Tyrphostin RG13022) is a tyrosine kinase inhibitor; inhibits the autophosphorylation reaction of the EGF receptor (IC50: 4 μM).</p>Fórmula:C16H14N2O2Pureza:98.38%Cor e Forma:SolidPeso molecular:266.29Scutellarein
CAS:<p>Scutellarein (6-Hydroxyapigenin) reduces inflammatory responses by inhibiting Src kinase activity.</p>Fórmula:C15H10O6Pureza:98.02% - 99.63%Cor e Forma:SolidPeso molecular:286.24PRT-060318
CAS:<p>PRT-060318 (P142-76) is a novel selective inhibitor of the Syk tyrosine kinase, as an approach to HIT treatment.</p>Fórmula:C18H24N6OPureza:99.98%Cor e Forma:SolidPeso molecular:340.42LDN-192960
CAS:<p>LDN-192960 is a potent inhibitor of Haspin and DYRK2 (IC50s: 10 nM and 48 nM).</p>Fórmula:C18H20N2O2SPureza:98.01% - 99.51%Cor e Forma:SolidPeso molecular:328.43SU14813
CAS:<p>SU14813: inhibits multiple kinases (VEGFR2, VEGFR1, PDGFRβ, KIT) with IC50s of 50, 2, 4, 15 nM; antiangiogenic and antitumor.</p>Fórmula:C23H27FN4O4Pureza:98.13%Cor e Forma:SolidPeso molecular:442.48AIM-100
CAS:<p>AIM-100 is a Ack1 inhibitor (IC50: 24 nM).</p>Fórmula:C23H21N3O2Pureza:98.91%Cor e Forma:SolidPeso molecular:371.43NRC-2694 hydrochloride
CAS:<p>NRC-2694 hydrochloride is an epidermal growth factor receptor (EGFR) antagonist potentially for the treatment of solid tumors.</p>Fórmula:C24H27ClN4O3Cor e Forma:SolidPeso molecular:454.95Baricitinib
CAS:<p>Baricitinib (INCB028050) is an orally JAK1 and JAK2 inhibitor. Baricitinib has anti-inflammatory and anti-tumor activity. Cost-effective and quality-assured.</p>Fórmula:C16H17N7O2SPureza:99% - >99.99%Cor e Forma:SolidPeso molecular:371.42Src Inhibitor 1
CAS:<p>Src Inhibitor 1 (Src Kinase Inhibitor 1) is a potent and selective dual site Src tyrosine kinase inhibitor.</p>Fórmula:C22H19N3O3Pureza:99.68% - >99.99%Cor e Forma:SolidPeso molecular:373.4Vimseltinib
CAS:<p>Vimseltinib (DCC-3014) is a c-FMS (CSF-IR) and c-Kit dual inhibitor (IC50s: <0.01 μM and 0.1-1 μM).</p>Fórmula:C23H25N7O2Pureza:99.05% - 99.57%Cor e Forma:SolidPeso molecular:431.49WS3
CAS:WS3, a β cell proliferation inducer, regulates Erb3 binding protein-1 (EBP1) and the IκB kinase pathway.Fórmula:C28H30F3N7O3Pureza:97.93% - 99.94%Cor e Forma:SolidPeso molecular:569.58CL-387785
CAS:<p>CL-387785 is an irreversible EGFR inhibitor with IC50 of 370 pM; overcomes T790M mutation resistance.</p>Fórmula:C18H13BrN4OPureza:99.56% - 99.62%Cor e Forma:SolidPeso molecular:381.23Zoligratinib
CAS:<p>Zoligratinib (CH5183284) is a selective and orally available FGFR inhibitor, which is for FGFR1, FGFR2, FGFR3, and FGFR4, respectively.</p>Fórmula:C20H16N6OPureza:95.28% - 99.51%Cor e Forma:SolidPeso molecular:356.38Remibrutinib
CAS:<p>Remibrutinib inhibits BTK activity with an IC50 value of 0.023 μM in blood.</p>Fórmula:C27H27F2N5O3Pureza:99.5% - 99.81%Cor e Forma:SolidPeso molecular:507.53Savolitinib
CAS:<p>Savolitinib (Volitinib) (AZD-6094) is an effective, selective, and orally bioavailable c-Met inhibitor (IC50s: 5 nM/3 nM for c-Met/p-Met).</p>Fórmula:C17H15N9Pureza:98.12%Cor e Forma:SolidPeso molecular:345.36Ribociclib
CAS:<p>Ribociclib (LEE011) is an orally available, and highly specific CDK4/6 inhibitor (IC50：10/39 nM).</p>Fórmula:C23H30N8OPureza:97.91% - >99.99%Cor e Forma:SolidPeso molecular:434.54(S)-Sunvozertinib
CAS:<p>(S)-Sunvozertinib (DZD9008) is a rationally designed selective, irreversible EGFR/HER2 inhibitor.</p>Fórmula:C29H35ClFN7O3Pureza:99.64%Cor e Forma:SolidPeso molecular:584.08BI-4020
CAS:<p>BI-4020 is a fourth-generation, orally active, and non-covalent inhibitor of EGFR tyrosine kinase.</p>Fórmula:C30H38N8O2Pureza:97.21% - >99.99%Cor e Forma:SolidPeso molecular:542.68Avitinib
CAS:<p>Avitinib (AC0010), also known as AC0010 or AC0010MA, is an orally available, irreversible, epidermal growth factor receptor (EGFR) mutant-selective inhibitor,</p>Fórmula:C26H26FN7O2Pureza:99.81% - >99.99%Cor e Forma:SolidPeso molecular:487.53Pyridone 6
CAS:<p>Pyridone 6, a selective JAK1/2/3 and Tyk2 inhibitor with IC50s: JAK1=15 nM, JAK2=1 nM, JAK3 (Ki=5 nM), Tyk2=1 nM; weakly binds other kinases (130 nM-10 μM).</p>Fórmula:C18H16FN3OPureza:97.1% - 98.74%Cor e Forma:SolidPeso molecular:309.34AG-1557 hydrochloride (189290-58-2(free base))
AG-1557 hydrochloride is an inhibitor of the epidermal growth factor receptor (EGFR) tyrosine kinase (pIC50: 8.194).Fórmula:C16H15ClIN3O2Pureza:98.64%Cor e Forma:SolidPeso molecular:443.66SRI 31215 TFA
CAS:<p>SRI 31215 TFA acts as a triplex inhibitor of matriptase, hepsin and HGFA and mimics the activity of HAI-1/2, endogenous inhibitors of HGF activation.</p>Fórmula:C27H34F3N5O3Pureza:98.25% - 99.97%Cor e Forma:SolidPeso molecular:533.6NVP-BHG712 isomer
CAS:<p>NVP-BHG712 isomer shows conserved non-bonded binding to EPHA2 and EPHB4.</p>Fórmula:C26H20F3N7OPureza:99.14%Cor e Forma:SolidPeso molecular:503.48Milciclib
CAS:<p>Milciclib (PHA-848125) is a potent CDK2 inhibitor with a 45 nM IC50, selective over CDK1/2/4/5/7. In Phase 2 trials.</p>Fórmula:C25H32N8OPureza:99.28%Cor e Forma:SolidPeso molecular:460.57Avitinib maleate
CAS:<p>Avitinib maleate is a pyrrolopyrimidine-based irreversible epidermal growth factor receptor (EGFR) inhibitor.</p>Fórmula:C30H30FN7O6Pureza:98% - 99.74%Cor e Forma:SolidPeso molecular:603.61RN486
CAS:<p>RN486 is an effective and specific BTK inhibitor (IC50: 4 nM).</p>Fórmula:C35H35FN6O3Pureza:99.38%Cor e Forma:SolidPeso molecular:606.69Daphnetin
CAS:<p>Daphnetin (7,8-Dihydroxycoumarin), a natural coumarin derivative, is a protein kinase inhibitor with inhibitory for EGFR (IC50: 7.67 μM), PKA (IC50: 9.33 μM),</p>Fórmula:C9H6O4Pureza:97.47% - 99.8%Cor e Forma:SolidPeso molecular:178.14H-89 dihydrochloride
CAS:<p>H-89 dihydrochloride (5-Isoquinolinesulfonamide) is a potent inhibitor of protein kinase A (PKA; IC50: 0.14 μM, Ki: 48 nM).</p>Fórmula:C20H20BrN3O2S·2HClPureza:98.22% - >99.99%Cor e Forma:SolidPeso molecular:519.28Spebrutinib
CAS:<p>Spebrutinib (LMK-435) is an orally bioavailable, selective inhibitor of Bruton's agammaglobulinemia tyrosine kinase (BTK), with potential antineoplastic</p>Fórmula:C22H22FN5O3Pureza:97.02% - >99.99%Cor e Forma:SolidPeso molecular:423.44Alflutinib mesylate
CAS:<p>Alflutinib mesylate (AST2818 mesylate) ,is an irreversible tyrosine kinase inhibitor that selectively inhibits EGFR mutations, especially T790M.</p>Fórmula:C29H35F3N8O5SPureza:97.94% - 99.63%Cor e Forma:SolidPeso molecular:664.7SU4984
CAS:<p>SU4984 is a cell-permeable, ATP-competitive and reversible inhibitor of the fibroblast growth factor receptor 1 (FGFR1).</p>Fórmula:C20H19N3O2Pureza:97.20%Cor e Forma:SolidPeso molecular:333.38KRN-633
CAS:<p>KRN-633 is an effective VEGFR inhibitor. The IC50s of KRN-633(KRN633) for VEGFR1, VEGFR2, and VEGFR3 is 170, 160 and 125 nM, respectively.</p>Fórmula:C20H21ClN4O4Pureza:99.53% - 99.73%Cor e Forma:SolidPeso molecular:416.86Crizotinib hydrochloride
CAS:<p>Crizotinib hydrochloride (PF-02341066 hydrochloride) is a novel inhibitor of anaplastic lymphoma kinase and c-Met(IC50s of 20 and 8 nM)</p>Fórmula:C21H23Cl3FN5OPureza:98.73% - 98.87%Cor e Forma:SolidPeso molecular:486.8Danusertib
CAS:<p>Danusertib (PHA-739358) is a small-molecule 3-aminopyrazole derivative with potential antineoplastic activity.</p>Fórmula:C26H30N6O3Pureza:97.88% - 98.79%Cor e Forma:White PowderPeso molecular:474.55PQ401 hydrochloride (196868-63-0(free base))
<p>PQ401 inhibits autophosphorylation of IGF-1R domain with IC50 of <1 μM.</p>Fórmula:C18H17Cl2N3O2Pureza:99.86%Cor e Forma:SolidPeso molecular:378.25Nintedanib esylate
CAS:<p>Nintedanib esylate (BIBF 1120 esylate) is a potent triple angiokinase inhibitor for VEGFR1/2/3, FGFR1/2/3 and PDGFRα/β</p>Fórmula:C31H33N5O4·C2H6O3SPureza:99.43% - 99.96%Cor e Forma:SolidPeso molecular:649.76SGI-7079
CAS:<p>SGI-7079: selective Axl inhibitor; hinders tumor growth dose-dependently; may target EGFR inhibitor resistance.</p>Fórmula:C26H26FN7Pureza:95.51% - 99.26%Cor e Forma:SolidPeso molecular:455.53FIIN-2
CAS:<p>FIIN-2, an irreversible, pan-FGFR inhibitor, inhibits FGFR1/2/3/4 with IC50 of 3.09 nM, 4.3 nM, 27 nM and 45.3 nM, respectively.</p>Fórmula:C35H38N8O4Pureza:97.82% - 99.65%Cor e Forma:Crystalline SolidPeso molecular:634.73(E)-AG 556
CAS:<p>AG 556 is a selective inhibitor of EGFR and blocks LPS-induced TNF-α production.</p>Fórmula:C20H20N2O3Pureza:99.93%Cor e Forma:Light Yellow PowderPeso molecular:336.38NSC 228155
CAS:<p>NSC 228155 is an activator of EGFR, binding to the sEGFR dimerization domain II and modulate EGFR tyrosine phosphorylation.</p>Fórmula:C11H6N4O4SPureza:99.84%Cor e Forma:SolidPeso molecular:290.25Afatinib Dimaleate
CAS:<p>Afatinib Dimaleate (BIBW 2992MA2) is an orally bioavailable anilino-quinazoline derivative and inhibitor of the EGFR family, with antineoplastic activity.</p>Fórmula:C32H33ClFN5O11Pureza:98.11% - 99.87%Cor e Forma:SolidPeso molecular:718.08AZD3229
CAS:<p>AZD3229 is a potent pan-KIT mutant inhibitor for the treatment of gastrointestinal stromal tumors.</p>Fórmula:C24H26FN7O3Pureza:98.83%Cor e Forma:SolidPeso molecular:479.51Mubritinib
CAS:<p>Mubritinib (TAK-165) (TAK-165) is a potent inhibitor of HER2/ErbB2 with IC50 of 6 nM.</p>Fórmula:C25H23F3N4O2Pureza:98.61% - 99.85%Cor e Forma:SolidPeso molecular:468.471-Naphthyl PP1 hydrochloride
CAS:<p>1-Naphthyl PP1 hydrochloride (1-NA-PP 1 hydrochloride) is a selective inhibitor of src family kinases v-Src</p>Fórmula:C19H20ClN5Pureza:98.63%Cor e Forma:SolidPeso molecular:353.85c-Kit-IN-1
CAS:<p>c-Kit-IN-1 (DCC-2618) is an effective inhibitor of c-Met and c-Kit (IC50s<200 nM).</p>Fórmula:C26H21F2N5O3Pureza:98.72% - 98.73%Cor e Forma:SolidPeso molecular:489.47Ki20227
CAS:<p>Ki-20227 is a specific c-Fms tyrosine kinase(CSF1R) inhibitor (IC50: 2 nM).</p>Fórmula:C24H24N4O5SPureza:98.97% - 99.88%Cor e Forma:SolidPeso molecular:480.54Nampt-IN-1
CAS:<p>Nampt-IN-1 (LSN3154567) (LSN3154567) is a potent and selective NAMPT inhibitor. Nampt-IN-1 inhibits purified NAMPT with an IC50 of 3.1 nM.</p>Fórmula:C20H25N3O5SPureza:99.28% - 99.4%Cor e Forma:SolidPeso molecular:419.49Alectinib hydrochloride
CAS:<p>Alectinib hydrochloride (RO5424802 Hydrochloride) is a selective, and orally available inhibitor of ALK( IC50 : 1.9 nM)</p>Fórmula:C30H35ClN4O2Pureza:99.61% - 99.96%Cor e Forma:SolidPeso molecular:519.08ALW-II-41-27
CAS:<p>ALW-II-41-27 (Eph receptor tyrosine kinase inhibitor), an Eph receptor tyrosine kinase inhibitor, is used for cancer therapy.</p>Fórmula:C32H32F3N5O2SPureza:97.01% - 99.52%Cor e Forma:SolidPeso molecular:607.69Dacomitinib
CAS:<p>Dacomitinib (PF299) is an oral selective inhibitor of EGFR, ERBB2, ERBB4 with IC50s: 6, 45.7, 73.7 nM.</p>Fórmula:C24H25ClFN5O2Pureza:99.4% - 99.72%Cor e Forma:SolidPeso molecular:469.94LDC1267
CAS:<p>LDC1267 is a excellently specific TAM(Tyro3, Axl and Mer) kinase inhibitor, for Mer( IC50<5 nM), Tyro3(IC50=8 nM), and Axl(IC50=29 nM).</p>Fórmula:C30H26F2N4O5Pureza:99.38% - 99.88%Cor e Forma:SolidPeso molecular:560.55Ruxolitinib (S enantiomer)
CAS:<p>Ruxolitinib S enantiomer (INCB18424) is the S-enantiomer of Ruxolitinib. Ruxolitinib is the first potent, selective JAK1/2 inhibitor.</p>Fórmula:C17H18N6Pureza:99.37% - 99.79%Cor e Forma:SolidPeso molecular:306.36Tyrphostin AG 528
CAS:<p>Tyrphostin AG 528 (Tyrphostin B66) is an inhibitor of EGFR (IC50: 4.9 μM) and ErbB2 (IC50: 2.1 μM).</p>Fórmula:C18H14N2O3Pureza:99.64%Cor e Forma:SolidPeso molecular:306.32Tyrphostin A9
CAS:<p>Tyrphostin A9 (SF 6847) is an Agricultural acaricide, now superseded. Tyrphostin A9 is firstly designed as an EGFR inhibitor</p>Fórmula:C18H22N2OPureza:98.21% - 99.87%Cor e Forma:Yellow SolidPeso molecular:282.38HPK1-IN-2
CAS:<p>HPK1-IN-2 is a strong, oral HPK1 inhibitor (IC50<0.05 μM), also blocking Lck, Flt3 kinases, with anticancer properties.</p>Fórmula:C19H20N6OSPureza:97.31%Cor e Forma:SolidPeso molecular:380.47LY2874455
CAS:<p>LY2874455 has been used in trials studying the treatment of Advanced Cancer.</p>Fórmula:C21H19Cl2N5O2Pureza:97.22% - 99.46%Cor e Forma:SolidPeso molecular:444.31Glumetinib
CAS:<p>Glumetinib (SCC244) (SCC 244) is a novel potent and selective inhibitor of c-Met kinase (IC50: 0.42 nM).</p>Fórmula:C21H17N9O2SPureza:99.79%Cor e Forma:SolidPeso molecular:459.48PP 3
CAS:<p>PP 3 is a Negative control for the Src kinase inhibitor PP 2</p>Fórmula:C11H9N5Pureza:98.61%Cor e Forma:Whit To Off-White SolidPeso molecular:211.22Telatinib
CAS:<p>Telatinib (Bay 57-9352) inhibits VEGFR2/3, c-Kit, PDGFRα with IC50s: 6 nM, 4 nM, 1 nM, 15 nM.</p>Fórmula:C20H16ClN5O3Pureza:97.61% - 99.81%Cor e Forma:SolidPeso molecular:409.83Ensartinib hydrochloride
CAS:<p>Ensartinib hydrochloride (X-396 dihydrochloride) is a potent new-generation ALK inhibitor with high activity against CNS metastases and a broad range of known</p>Fórmula:C26H29Cl4FN6O3Pureza:98.73%Cor e Forma:SolidPeso molecular:634.36MID-1
CAS:<p>MID-1 is an inhibitor of MG53-IRS-1 (Mitsugumin 53-Insulin Receptor Substrate-1) interaction.</p>Fórmula:C12H11N3O4SPureza:99.39%Cor e Forma:SolidPeso molecular:293.3Periplocin
CAS:<p>Periplocin fights lung cancer, induces apoptosis, stunts growth via beta-catenin/Tcf, and treats rheumatoid arthritis/traditional ailments.</p>Fórmula:C36H56O13Pureza:99.66% - 99.74%Cor e Forma:SolidPeso molecular:696.82UNC569
CAS:<p>UNC569 selectively inhibits kidney URAT1, regulating uric acid excretion and aiding gout patient's uric balance.</p>Fórmula:C22H29FN6Pureza:98.91% - 99.67%Cor e Forma:SolidPeso molecular:396.5CGI-1746
CAS:<p>CGI1746 is a potent and highly selective small-molecule Btk inhibitor with IC50 of 1.9 nM.</p>Fórmula:C34H37N5O4Pureza:97.69% - 97.88%Cor e Forma:SolidPeso molecular:579.69Altiratinib
CAS:<p>Altiratinib (DCC-2701)(DCC-2701) is a novel c-MET/TIE-2/VEGFR inhibitor; effectively reduce tumor burden in vivo and block c-MET pTyr(1349)-mediated signaling,</p>Fórmula:C26H21F3N4O4Pureza:99.67% - 99.75%Cor e Forma:SolidPeso molecular:510.46Ehp-inhibitor-2
CAS:<p>Ehp-inhibitor-2 is an Eph family tyrosine kinase inhibitor targeting Eph receptors.</p>Fórmula:C17H13N5OPureza:97.88%Cor e Forma:SolidPeso molecular:303.32GIP (1-30) amide, porcine acetate
<p>GIP (1-30) amide, porcine is a GIP receptor agonist that stimulates insulin and mildly inhibits gastric acid.</p>Fórmula:C164H249N41O49SPureza:98.50%Cor e Forma:SolidPeso molecular:3611.04SB1317 hydrochloride (1204918-72-8(free base))
<p>SB1317 hydrochloride (1204918-72-8(free base)) (TG-02 hydrochloride) is an effective inhibitor of CDK2/JAK2/FLT3 (IC50: 13/73/56 nM).</p>Fórmula:C23H25ClN4OPureza:99.84%Cor e Forma:SolidPeso molecular:408.92Osimertinib
CAS:<p>Osimertinib (AZD-9291) is a small molecule tyrosine kinase receptor inhibitor and antineoplastic agent that is used in the therapy of selected forms of NSCLC.</p>Fórmula:C28H33N7O2Pureza:99.32% - >99.99%Cor e Forma:SolidPeso molecular:499.61EGFR/ErbB-2/ErbB-4 inhibitor-2
CAS:<p>EGFR/ErbB-2/ErbB-4 inhibitor-2 (EGFR/ErbB2 Inhibitor) is a cell-permeable inhibitor of EGFR and c-ErbB2 (IC50s = 20 and 79 nM, respectively)</p>Fórmula:C23H21N3O3Pureza:99.55%Cor e Forma:SolidPeso molecular:387.43CHIR-98014
CAS:<p>CHIR-98014 (CT98014) is a selective GSK3 inhibitor; potentiate insulin activation of glucose transport and utilization in vitro and in vivo.</p>Fórmula:C20H17Cl2N9O2Pureza:97.25% - 99.59%Cor e Forma:SolidPeso molecular:486.31CREBtide acetate(149155-45-3 free base)
<p>CREBtide acetate is a synthetic substrate for PKA (Km=3.9 μM), which is based on the phosphorylation sequence in d-CREB (cAMP response element binding protein).</p>Fórmula:C75H133N29O21Pureza:96.13%Cor e Forma:SolidPeso molecular:1777.07SU5208
CAS:<p>SU5208 (3-[(Thien-2-yl)methylene]-2-indolinone) is a compound with bioactivity.SU5208 inhibits vascular endothelial growth factor receptor-2 (VEGFR2).</p>Fórmula:C13H9NOSPureza:99.62%Cor e Forma:SolidPeso molecular:227.28Olmutinib
CAS:<p>Olmutinib (BI1482694) is a Novel Epidermal Growth Factor Receptor Tyrosine Kinase Inhibitor</p>Fórmula:C26H26N6O2SPureza:99.14%Cor e Forma:SolidPeso molecular:486.59Taletrectinib
CAS:<p>Taletrectinib (AB-106) is a new-generation selective inhibitor of ROS1/NTRK including ROS1,NTRK1,NTRK2 and NTRK3.</p>Fórmula:C29H34FN5O5Pureza:99.87% - 99.96%Cor e Forma:SolidPeso molecular:551.61WHI-P180
CAS:<p>WHI-P180 (Janex 3) is a potent EGFR and Cdk2 inhibitors with IC50 of 4.0 and 1.0 uM, respectively.</p>Fórmula:C16H15N3O3Pureza:99.21%Cor e Forma:SolidPeso molecular:297.31BMS 777607
CAS:<p>BMS 777607 (BMS 817378) is a Met-related inhibitor for c-Met/Axl/Ron/Tyro3. BMS-777607 has been investigated for the basic science of Malignant Solid Tumour.</p>Fórmula:C25H19ClF2N4O4Pureza:98.30% - >99.99%Cor e Forma:SolidPeso molecular:512.89Butein
CAS:<p>Butein is a cAMP-specific PDE inhibitor, protein tyrosine kinase inhibitor, and SIRT1 activator.Cost-effective and quality-assured.</p>Fórmula:C15H12O5Pureza:98.76% - >99.99%Cor e Forma:SolidPeso molecular:272.25TL-895
CAS:<p>TL-895 is a potent, selective ATP-competitive BTK inhibitor (IC50 = 1.5 nM, Ki = 11.9 nM).</p>Fórmula:C25H26FN5O2Pureza:99.96%Cor e Forma:SolidPeso molecular:447.5SU 5402
CAS:<p>SU 5402 is a potent multi-targeted receptor tyrosine kinase inhibitor with IC50 of 20 nM, 30 nM, and 510 nM for VEGFR2, FGFR1, and PDGF-Rβ, respectively.</p>Fórmula:C17H16N2O3Pureza:98.91% - 99.64%Cor e Forma:Yellow-Green SolidPeso molecular:296.32SKLB 610
CAS:<p>SKLB610, a novel multi-targeted inhibitor, inhibits angiogenesis-related tyrosine kinase VEGFR2, FGFR2, and PDGFR at a rate of 97%, 65%, and 55%, respectively,</p>Fórmula:C21H16F3N3O3Pureza:99.33% - 99.83%Cor e Forma:SolidPeso molecular:415.37MK-8033
CAS:<p>MK-8033 is a new and selective dual ATP competitive c-Met/Ron inhibitor (IC50: 1 nM Wt c-Met).</p>Fórmula:C25H21N5O3SPureza:97.16%Cor e Forma:SolidPeso molecular:471.53CEP-28122
CAS:<p>CEP-28122 is a highly potent and selective orally active ALK inhibitor.</p>Fórmula:C28H35ClN6O3Pureza:99.87% - >99.99%Cor e Forma:SolidPeso molecular:539.07GLPG0634 analog
CAS:<p>GLPG0634 analog (GLPG0634 analogue) is a specific JAK1 inhibitor with IC50 of 10/28/810/116 nM for JAK1/2/3 and TYK2, respectively.</p>Fórmula:C23H18N6O2Pureza:99.52% - >99.99%Cor e Forma:SolidPeso molecular:410.43PD158780
CAS:<p>PD 158780 blocks all ErbB receptors: EGFR, ErbB2-4, with IC50s: 8μM, 49-52 nM.</p>Fórmula:C14H12BrN5Pureza:98.81%Cor e Forma:SolidPeso molecular:330.18Eph inhibitor 2
CAS:<p>Eph inhibitor 2 is an Eph family tyrosine kinase inhibitor targeting Eph receptors.</p>Fórmula:C18H15N5OPureza:99.01%Cor e Forma:SolidPeso molecular:317.34FGFR4-IN-1
CAS:<p>FGFR4-IN-1 is a potent FGFR4 inhibitor (IC50: 0.7 nM).</p>Fórmula:C24H27N7O5Pureza:98.96%Cor e Forma:SolidPeso molecular:493.52SU5204
CAS:<p>SU5204 (3-[(2-Ethoxyphenyl)methylidene]-1H-indol-2-one), an analogue of SU5025, pharmacologically inhibits VEGFR2(IC50s of 4 and 51.5 μM for FLK-1 (VEGFR-2) and</p>Fórmula:C17H15NO2Pureza:99.46%Cor e Forma:SolidPeso molecular:265.31PP2
CAS:<p>PP2 (AG 1879,AGL 1879) is a effective inhibitor of Lck/Fyn (IC50:4/5 nM) , ~100-fold less potent to EGFR, inactive for ZAP-70, PKA and JAK2.</p>Fórmula:C15H16ClN5Pureza:98% - 98.21%Cor e Forma:White SolidPeso molecular:301.77Tyrphostin AG30
CAS:<p>Tyrphostin AG30 (AG30) (AG30) is a potent protein tyrosine kinases (PTK) inhibitor.</p>Fórmula:C10H7NO4Pureza:99.02%Cor e Forma:SolidPeso molecular:205.17PD-161570
CAS:<p>PD-161570 is a potent and ATP-competitive human FGF-1 receptor inhibitor with an IC50 of 39.9 nM and a Ki of 42 nM.</p>Fórmula:C26H35Cl2N7OPureza:99.92%Cor e Forma:SolidPeso molecular:532.51Lazertinib
CAS:<p>Lazertinib (GNS-1480) is a potent, selective, irreversible EGFR-TKI; IC50: 1.7-76 nM for various EGFR mutations.</p>Fórmula:C30H34N8O3Pureza:98.7% - 99.90%Cor e Forma:SolidPeso molecular:554.64Tivozanib
CAS:<p>Tivozanib (KRN951) is an oral VEGFRs 1-3 inhibitor with potential antiangiogenic and cancer-fighting properties.</p>Fórmula:C22H19ClN4O5Pureza:98.08% - 99.67%Cor e Forma:SolidPeso molecular:454.86β-Hydroxyisovalerylshikonin
CAS:<p>Beta-Hydroxyisovalerylshikonin is an inhibitor of protein-tyrosine kinases such as v-Src and EGFR, and has been shown to induce apoptosis in several human tumor</p>Fórmula:C21H24O7Pureza:98.16%Cor e Forma:SolidPeso molecular:388.41PKG drug G1
CAS:<p>PKG drug G1 targets PKG Iα C42. PKG drug G1 can couple to vasodilation and blood pressure lowering by a C42 PKG Iα-independent mechanism.</p>Fórmula:C13H11N3OSPureza:97.57% - 97.67%Cor e Forma:SolidPeso molecular:257.31UNC2025 2HCl (1429881-91-3(free base))
<p>UNC2025 is a potent and orally bioavailable Mer/Flt3 dual inhibitor with IC50 of 0.8/0.74 nM for Mer/Flt3.</p>Fórmula:C28H42Cl2N6OPureza:99.71%Cor e Forma:SolidPeso molecular:549.62PRN1371
CAS:<p>PRN1371 is a specific and potent FGFR1-4 and CSF1R inhibitor (IC50s: 0.6/1.3/4.1/19.3/8.1 nM for FGFR1/2/3/4 and CSF1R).</p>Fórmula:C26H30Cl2N6O4Pureza:98.65%Cor e Forma:SolidPeso molecular:561.46MAZ51
CAS:<p>MAZ51 is a VEGFR-3 (Flt-4) tyrosine kinase inhibitor.</p>Fórmula:C21H18N2OPureza:98.53%Cor e Forma:SolidPeso molecular:314.38Vactosertib
CAS:<p>Vactosertib (EW-7197) is an oral TGFBR1/ALK5 inhibitor with potential cancer-fighting properties.</p>Fórmula:C22H18FN7Pureza:98.85% - 99.81%Cor e Forma:SolidPeso molecular:399.42Dacomitinib hydrate
CAS:<p>Dacomitinib hydrate (PF 299804) is a highly selective and second-generation small-molecule inhibitor of the pan-epidermal growth factor receptor family of</p>Fórmula:C24H27ClFN5O3Pureza:99.52%Cor e Forma:SolidPeso molecular:487.96AZD2932
CAS:<p>AZD2932 is a potent and multi-targeted kinase inhibitor VEGFR2, PDGFβ, Flt-3, and c-Kit.</p>Fórmula:C24H25N5O4Pureza:97.71% - 98.37%Cor e Forma:SolidPeso molecular:447.49CH7057288
CAS:<p>CH7057288 is an effective and selective TRK inhibitor with an IC50 value of 1.1 nM, 7.8 nM and 5.1 nM for TRKA, TRKB and TRKC, respectively.</p>Fórmula:C32H31N3O5SPureza:99.92%Cor e Forma:SolidPeso molecular:569.67TAS6417
CAS:<p>Zipalertinib (TAS6417, CLN-081) is a novel, highly potent, orally active covalent EGFR tyrosine kinase inhibitor.Cost-effective and quality-assured.</p>Fórmula:C23H20N6OPureza:99.71%Cor e Forma:SolidPeso molecular:396.44Pyridostatin TFA
CAS:<p>Pyridostatin Trifluoroacetate Salt is a G-quadruplexe stabilizer with Kd of 490 nM in a cell-free assay, which targets a series of proto-oncogenes including c-</p>Fórmula:C37H35F9N8O11Pureza:97.09% - 99.84%Cor e Forma:SolidPeso molecular:938.71SCR-1481B1
CAS:<p>SCR-1481B1 (c-Met inhibitor 2) has activity against cancers dependent on Met activation and also has activity against cancers as a VEGFR inhibitor</p>Fórmula:C32H40ClF2N6O13PPureza:98.07%Cor e Forma:SolidPeso molecular:821.12Pralsetinib
CAS:<p>Pralsetinib (Blu667) (BLU-667) is a highly potent, selective RET inhibitor (IC50s: 0.4, 0.3, 0.4, 0.4, and 0.4 nM for WT RET, RET mutants V804L, V804M, M918T</p>Fórmula:C27H32FN9O2Pureza:97.88% - 99.8%Cor e Forma:SolidPeso molecular:533.6LDN-214117
CAS:<p>LDN-214117 is a potent and selective ALK2 inhibitor.</p>Fórmula:C25H29N3O3Pureza:98% - 99.82%Cor e Forma:SolidPeso molecular:419.52RG14620
CAS:<p>RG14620 (Tyrphostin RG14620) is an epidermal growth factor receptor (EGFR) inhibitor.</p>Fórmula:C14H8Cl2N2Pureza:99.82% - 99.87%Cor e Forma:SolidPeso molecular:275.13
