Autofagia
Os inibidores da autofagia têm como alvo o processo celular de autofagia, que envolve a degradação e reciclagem de componentes celulares através dos lisossomas. A autofagia é um mecanismo crítico para a manutenção da homeostase celular, mas sua desregulação está implicada em várias doenças, incluindo câncer, neurodegeneração e infecções. Os inibidores da autofagia podem bloquear este processo, tornando-os ferramentas valiosas para estudar o papel da autofagia nas doenças e desenvolver estratégias terapêuticas. Na CymitQuimica, oferecemos inibidores da autofagia para apoiar sua pesquisa em biologia celular, oncologia e doenças neurodegenerativas.
Foram encontrados 1424 produtos de "Autofagia"
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GSK621
CAS:<p>GSK621 is a specific and potent AMPK activator.</p>Fórmula:C26H20ClN3O5Pureza:97.02% - 97.05%Cor e Forma:SolidPeso molecular:489.91Regorafenib
CAS:<p>Regorafenib (BAY 73-4506) is a multi-targeted receptor tyrosine kinase inhibitor that inhibits RET, C-RAF, VEGFR2, c-Kit, VEGFR1, and PDGFRβ and is orally</p>Fórmula:C21H15ClF4N4O3Pureza:98% - 99.95%Cor e Forma:SolidPeso molecular:482.82Enalaprilat Dihydrate
CAS:<p>Enalaprilat Dihydrate (MK-422 Dihydrate) （IC50=1.94 nM） is a potent angiotensin-converting enzyme (ACE) inhibitor.</p>Fórmula:C18H24N2O5·2H2OPureza:99.46% - 99.78%Cor e Forma:SolidPeso molecular:348.43BDO
CAS:<p>3BDO is a new mTOR activator. 3BDO inhibits autophagy.</p>Fórmula:C18H17NO5Pureza:97.76%Cor e Forma:SolidPeso molecular:327.33Mavorixafor trihydrochloride
CAS:<p>Mavorixafor trihydrochloride blocks CXCR4 (IC50: 13 nM) and suppresses T-tropic HIV-1 replication (IC50: 1-9 nM). It's orally active.</p>Fórmula:C21H30Cl3N5Pureza:98.00%Cor e Forma:SolidPeso molecular:458.86Mirdametinib
CAS:<p>Mirdametinib (PD325901) is an MEK inhibitor (IC50=0.33 nM) with selective, non-ATP-competitive, and oral activity.</p>Fórmula:C16H14F3IN2O4Pureza:99.11% - 99.63%Cor e Forma:White PowderPeso molecular:482.19SP600125
CAS:<p>SP600125 (JNK Inhibitor II) is a JNK inhibitor that inhibits JNK1, JNK2, and JNK3 (IC50=40/40/90 nM) with oral potency, reversibility, and ATP-competitive</p>Fórmula:C14H8N2OPureza:97.63% - 99.82%Cor e Forma:SolidPeso molecular:220.233-Bromopyruvic acid
CAS:<p>3-Bromopyruvic acid (Hexokinase II Inhibitor II, 3-BP) is a hexokinase II inhibitor with Ki of 2.4 mM for glycolysis/hexokinase inhibition.</p>Fórmula:C3H3BrO3Pureza:95% - 99.644%Cor e Forma:White To Pale Yellow Crystalline PowderPeso molecular:166.96Pseudolaric Acid B
CAS:<p>Pseudolaric acid B, a natural diterpenoid compound, is isolated from Pseudolarix kaempferi.</p>Fórmula:C23H28O8Pureza:98.91% - 99.84%Cor e Forma:SolidPeso molecular:432.46FIPI
CAS:<p>FIPI, a halopemide derivative, strongly blocks PLD1 and PLD2 (IC50s: 25 nM, 20 nM) and hinders PLD-mediated cell activity.</p>Fórmula:C23H24FN5O2Pureza:97.21% - 98.68%Cor e Forma:SolidPeso molecular:421.47Regorafenib monohydrate
CAS:<p>Regorafenib Monohydrate is a novel oral multikinase inhibitor with IC50 values of 13, 4.2, 46, 22, 7, 1.5, 2.5, 28, 19 nM for VEGFR1, murine VEGFR2, murine</p>Fórmula:C21H17ClF4N4O4Pureza:99.69%Cor e Forma:SolidPeso molecular:500.83Oleanolic Acid
CAS:<p>Oleanolic Acid (Caryophyllin) is a natural compound with anti-tumor activities, which are widely distributed in plants.</p>Fórmula:C30H48O3Pureza:97.04% - 98.51%Cor e Forma:SolidPeso molecular:456.7GW 4064
CAS:<p>GW 4064 is an effective farnesoid X receptor (FXR) agonist (EC50 =65 nM).</p>Fórmula:C28H22Cl3NO4Pureza:98% - 99.94%Cor e Forma:SolidPeso molecular:542.84Glucosamine sulfate
CAS:<p>Glucosamine sulfate (D-Glucosaminesulfate) was extracted from synthetic product;Store the product in sealed, cool and dry condition.</p>Fórmula:C6H13NO5·H2SO4Pureza:99.64%Cor e Forma:White CrystalPeso molecular:277.25JZL195
CAS:<p>JZL195 is a selective and efficacious dual FAAH/MAGL inhibitor.</p>Fórmula:C24H23N3O5Pureza:99.81%Cor e Forma:SolidPeso molecular:433.46ZSTK474
CAS:<p>PI3K Inhibitor ZSTK474 is an orally available, s-triazine derivative, ATP-competitive phosphatidylinositol 3-kinase (PI3K) inhibitor with potential</p>Fórmula:C19H21F2N7O2Pureza:98.29% - 99.95%Cor e Forma:White PowderPeso molecular:417.41Obeticholic Acid
CAS:<p>Obeticholic Acid (6-ECDCA, INT-747) is a high-affinity, semisynthetic, bile acid-derived FXR agonist.Cost-effective and quality-assured.</p>Fórmula:C26H44O4Pureza:99.88% - 99.97%Cor e Forma:SolidPeso molecular:420.63Torin 2
CAS:<p>Torin 2: mTOR inhibitor, IC50=0.25 nM, 800x more selective than PI3K, with EC50=28/35/118 nM for ATM/ATR/DNA-PK.</p>Fórmula:C24H15F3N4OPureza:98.31% - 99.32%Cor e Forma:SolidPeso molecular:432.4BC1618
CAS:<p>BC1618 (2-Propanol, 1-[bis(phenylmethyl)amino]-3-[4-(trifluoromethyl)phenoxy]-) is an orally active Fbxo48 inhibitor that stimulates Ampk-dependent signaling.</p>Fórmula:C24H24F3NO2Pureza:99.95%Cor e Forma:SolidPeso molecular:415.45Genipin
CAS:<p>Genipin ((+)-Genipin), an active aglycone derived from an iridoid glycoside called geniposide, is found in the fruit of Gardenia jasminoides Ellis.</p>Fórmula:C11H14O5Pureza:99.09% - 99.21%Cor e Forma:SolidPeso molecular:226.23
