
HIV Protease
Os inibidores da protease do HIV são uma classe de medicamentos antirretrovirais que têm como alvo específico a enzima protease do vírus da imunodeficiência humana (HIV). Ao inibir esta enzima, esses compostos impedem o vírus de processar suas poliproteínas em proteínas maduras e funcionais, bloqueando assim a produção de novos virions infecciosos. Os inibidores da protease do HIV são um pilar da terapia antirretroviral altamente ativa (HAART) utilizada para o tratamento do HIV/AIDS. Na CymitQuimica, oferecemos uma variedade de inibidores da protease do HIV para apoiar sua pesquisa em tratamento do HIV, resistência a medicamentos e virologia.
Foram encontrados 447 produtos de "HIV Protease"
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APOBEC3G-IN-1
CAS:<p>APOBEC3G-IN-1 (MN136.0185) is a targeted APOBEC3G inhibitor with anti-HIV activity for the study of infectious diseases and cancer.</p>Fórmula:C15H11NO3Pureza:96.54%Cor e Forma:SolidPeso molecular:253.25HIV-IN-6
CAS:<p>HIV-IN-6, an anti-HIV agent, blocks replication by targeting SFKs like Hck involved with Nef protein.</p>Fórmula:C20H16N4O3SPureza:97.12%Cor e Forma:SolidPeso molecular:392.43HIV-1 inhibitor-49
<p>HIV-1 inhibitor-49, an oral HEPT analog, has strong pharmacokinetics, potent reverse transcriptase inhibition (IC50=30nM), and is safe in mice.</p>Fórmula:C21H18F2N2O3SCor e Forma:SolidPeso molecular:416.44MK-2048
CAS:<p>MK-2048 is a potent inhibitor of integrase (IN) and INR263K with IC50 of 2.6 nM and 1.5 nM, respectively.</p>Fórmula:C21H21ClFN5O4Pureza:98%Cor e Forma:SolidPeso molecular:461.87HIV-1 inhibitor-22
CAS:<p>HIV-1 inhibitor-22 effectively blocks HIV-1 RT (IC50=3.63 μM) with low cytotoxicity (CC50 > 227 μM).</p>Fórmula:C30H26N6O3SCor e Forma:SolidPeso molecular:550.63HIV-1 integrase inhibitor 4
CAS:<p>HIV-1 integrase inhibitor 4 is an HIV-1 integrase strand transfer (INST) inhibitor (IC50: 3.7 nM).</p>Fórmula:C24H20F2N4O5SPureza:98%Cor e Forma:SolidPeso molecular:514.5HIV-1 inhibitor-29
CAS:<p>HIV-1 inhibitor-29: Blocks HIV-1 IIIB (EC50: 2.18μM), resists F227L/V106A (EC50: 0.974μM), low toxicity (CC50: 211μM), for AIDS research.</p>Fórmula:C30H36N6O5Cor e Forma:SolidPeso molecular:560.64D77
CAS:<p>D77 is anti-HIV-1 inhibitor. D77 inhibits HIV-1(IIIB) replication by EC50 value of 23.8 μg/ml in MT-4 cell (5.03 μg/ml for C8166 cells).</p>Fórmula:C28H22BrNO7SPureza:98%Cor e Forma:SolidPeso molecular:596.45HIV-1 inhibitor-34
CAS:<p>HIV-1 inhibitor-34 (5q): potent, selective; EC50: 6.4 nM; MT-4 CC50: 16 μM; useful in AIDS research.</p>Fórmula:C26H27N7OCor e Forma:SolidPeso molecular:453.54HIV-IN-4
CAS:<p>HIV-IN-4 (Compound 12) is a potent HIV inhibitor that exhibits promising anti-HIV activities [1].</p>Fórmula:C14H18N2O3Cor e Forma:SolidPeso molecular:262.3HIV-1 inhibitor-16
CAS:<p>HIV-1 inhibitor-16: potent with EC50 1.3 nM for wild-type; inhibits K103N, E138K, Y181C, L100I strains; good solubility; stable; low CYP impact; non-toxic.</p>Fórmula:C23H16F2N6Cor e Forma:SolidPeso molecular:414.41HIV-1 inhibitor-57
CAS:<p>HIV-1 Inhibitor-57 (Compound 12g) is an antiviral agent that potently inhibits both wild-type and five common NNRTI-resistant strains of HIV-1, exhibiting EC50</p>Fórmula:C25H24FN5O3SCor e Forma:SolidPeso molecular:493.55SARS-CoV-IN-3
CAS:<p>SARS-CoV-IN-3 is an effective SARS-CoV replication inhibitor.</p>Fórmula:C25H28ClFeN3OPureza:98%Cor e Forma:SolidPeso molecular:477.81Mesoxalic acid
CAS:<p>Mesoxalic acid is a dicarboxylic acid and a ketonic acid which blocks RT translocation.</p>Fórmula:C3H2O5Pureza:98%Cor e Forma:SolidPeso molecular:118.04SAMT-247
CAS:<p>SAMT-247 is an HIV inhibitor that acts by modifying the nucleocapsid NCp7 region of Gag in infected cells and blocking Gag processing and reducing infectivity.</p>Fórmula:C12H14N2O3SCor e Forma:SolidPeso molecular:266.32TMC310911
CAS:<p>TMC310911 is an oral HIV-1 protease inhibitor with an EC50 of 2.2-14.2 nM, effective against various HIV-1 strains.</p>Fórmula:C38H53N5O7S2Pureza:98%Cor e Forma:SolidPeso molecular:755.99Reverse transcriptase-IN-3
<p>Reverse transcriptase-IN-3, a pyrimidine carboxamide, inhibits HIV-1 including mutant strains.</p>Fórmula:C28H31N7O4SCor e Forma:SolidPeso molecular:561.66DQBS
CAS:<p>DQBS is an HIV-1 Nef function antagonist.</p>Fórmula:C22H17ClN4O4SPureza:98%Cor e Forma:SolidPeso molecular:468.91HIV-1 integrase inhibitor 7
CAS:<p>HIV-1 integrase inhibitor 7 is a potent HIV-1 integrase inhibitor (IC50: 33.3 nM).</p>Fórmula:C30H26O16Pureza:98%Cor e Forma:SolidPeso molecular:642.52β-L-D4A
CAS:<p>beta-L-D4A inhibits HIV-1 reverse transcriptase, stopping DNA synthesis.</p>Fórmula:C10H11N5O2Pureza:99.45%Cor e Forma:SolidPeso molecular:233.23
