mTOR
Os inibidores de mTOR são compostos que inibem a atividade do Alvo da Rapamicina em Mamíferos (mTOR), um regulador central do crescimento celular, proliferação, metabolismo e sobrevivência. A via de sinalização mTOR é frequentemente alterada em casos de câncer e outras doenças, tornando o mTOR um alvo crítico para intervenções terapêuticas. Inibidores de mTOR são amplamente utilizados em pesquisas relacionadas ao câncer, envelhecimento e distúrbios metabólicos. Na CymitQuimica, oferecemos uma variedade de inibidores de mTOR para apoiar sua pesquisa em transdução de sinais, oncologia e desenvolvimento terapêutico.
Foram encontrados 144 produtos de "mTOR"
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ETP-46464
CAS:<p>ETP-46464 is an effective and specific ATR inhibitor (IC50: 25 nM).</p>Fórmula:C30H22N4O2Pureza:97.76%Cor e Forma:SolidPeso molecular:470.52BGT226 maleate
CAS:<p>BGT226 maleate (NVP-BGT226) is a class I PI3K/mTOR inhibitor for PI3Kα/β/γ (IC50: 4/63/38 nM) .</p>Fórmula:C28H25F3N6O2·C4H4O4Pureza:97.75% - 98.78%Cor e Forma:SolidPeso molecular:650.6NVP-BBD130
CAS:<p>NVP-BBD130 is a stable, ATP-competitive, potent, orally active inhibitor of PI3K and mTOR.</p>Fórmula:C28H21N5OCor e Forma:SolidPeso molecular:443.5PI3K/mTOR Inhibitor-13
CAS:<p>PI3K/mTOR Inhibitor-13, an oral dual blocker of PI3K and mTOR, may treat sexual diseases, solid tumors, and IPF.</p>Fórmula:C20H13F2N5O3SCor e Forma:SolidPeso molecular:441.41PI3Ka-IN-5
CAS:<p>PI3Ka-IN-5 is a potent PI3Kα/mTOR inhibitor, with an IC 50 of 0.7 nM and 3.3 nM, respectively. PI3Ka-IN-5 can be used for the research of colorectal cancer .</p>Fórmula:C30H35N9O5Cor e Forma:SolidPeso molecular:601.66PKI-179
CAS:<p>PKI-179: Dual PI3K/mTOR inhibitor, orally active, IC50s: 0.42-77 nM, targets E545K and H1047R, antitumor in vivo.</p>Fórmula:C25H28N8O3Cor e Forma:SolidPeso molecular:488.54PKI-179 hydrochloride
CAS:<p>PKI-179: oral PI3K/mTOR inhibitor; IC50: PI3Kα/β/δ/γ (8-74 nM), PI3Kα mutants (11-14 nM), mTOR (0.42 nM); selective; inhibits cancer cell growth.</p>Fórmula:C25H29ClN8O3Cor e Forma:SolidPeso molecular:525PI3K/mTOR Inhibitor-8
CAS:<p>PI3K/mTOR Inhibitor-8: Dual PI3Kα (IC50: 0.46 nM) & mTOR (IC50: 12 nM) inhibitor; blocks G1/S phase & induces apoptosis in HCT-116 cells.</p>Fórmula:C23H22N8O4SCor e Forma:SolidPeso molecular:506.54eCF-309
CAS:<p>eCF-309 is a potent mTOR inhibitor with IC50 value of 15 nM.</p>Fórmula:C18H21N7O3Cor e Forma:SolidPeso molecular:383.4PI3K/mTOR Inhibitor-4
CAS:<p>Oral PI3K/mTOR Inhibitor-4 targets PI3Kα, γ, δ, mTOR; IC50s: 0.63, 22, 9.2, 13.85 nM. Used in cancer research.</p>Fórmula:C27H22FN3O6SCor e Forma:SolidPeso molecular:535.54PI3-Kinase α Inhibitor 2
CAS:<p>Phosphatidylinositol 3-kinase (PI3K) catalyzes the phosphorylation of the 3' hydroxyl position of PIs to produce the second messengers PtdIns-(3,4)-P2 and</p>Fórmula:C16H15N3O2SCor e Forma:SolidPeso molecular:313.37OXA-01
CAS:<p>OXA-01 is a potent mTORC1 and mTORC2 inhibitor, with IC 50 values of 29 nM and 7 nM, respectively [1]. OXA-01 demonstrates broad anti-tumor activity.</p>Fórmula:C21H20ClN5O2Cor e Forma:SolidPeso molecular:409.87FT-1518
CAS:<p>FT-1518 is an orally available, selective and potent mTORC1 and mTORC2 inhibitor with anticancer and antitumor activity for cancer research.</p>Fórmula:C20H26N8OPureza:98.34% - 98.80%Cor e Forma:SolidPeso molecular:394.47P-2281
CAS:<p>P-2281 is an mTOR inhibitor with anticancer and anti-inflammatory properties.P-2281 inhibits dextran sulfate sodium (DSS)-induced colitis by suppressing T-cell</p>Fórmula:C9H8ClN3OPureza:99.95%Cor e Forma:SolidPeso molecular:209.63mTOR inhibitor-2
CAS:<p>mTOR inhibitor-2 is an inhibitor of selective and oral mTOR (IC50 of 7 nM).</p>Fórmula:C23H21N7OPureza:98%Cor e Forma:SolidPeso molecular:411.46PI3K/mTOR Inhibitor-2
CAS:<p>Potent PI3K/mTOR Inhibitor-2 targets PI3Kα/β/δ/γ & mTOR (IC50: 3.4, 34, 16,1, 4.7 nM); exhibits antitumor effects.</p>Fórmula:C20H13ClF2N4O4SPureza:96.16%Cor e Forma:SolidPeso molecular:478.86PI3K/mTOR Inhibitor-9
CAS:<p>PI3K/mTOR Inhibitor-9 acts on mTOR (38 nM IC50) and PI3Kα/γ (6.6 nM IC50), PI3Kδ (0.8 nM IC50).</p>Fórmula:C23H27N7O2Cor e Forma:SolidPeso molecular:433.51PP30
CAS:<p>PP30 is an inhibitor of mTORC1 and mTORC2. It is selective within the PI3K family, inhibiting other PI3Ks only at high concentrations.</p>Fórmula:C18H19N7OSPureza:98%Cor e Forma:SolidPeso molecular:381.45PI3K/mTOR Inhibitor-3
CAS:<p>PI3K/mTOR Inhibitor-3, a potent dual-action anti-cancer imidazoline, targets PI3K and mTOR.</p>Fórmula:C22H23N5OCor e Forma:SolidPeso molecular:373.45PI-540
CAS:<p>PI-540 is a potent and selective inhibitor of class 1A phosphatidylinositide 3-kinases (PI3K).</p>Fórmula:C22H27N5O2SCor e Forma:SolidPeso molecular:425.55
