Sinalização Citoesquelética
Os inibidores de sinalização do citoesqueleto são compostos que interrompem as vias de sinalização que regulam o citoesqueleto, crucial para a forma celular, motilidade, divisão e transporte intracelular. Esses inibidores são usados para estudar a dinâmica das proteínas do citoesqueleto, como actina e tubulina, e seu papel em processos como migração celular, adesão e metástase do câncer. Os inibidores de sinalização do citoesqueleto são valiosos na pesquisa em biologia celular, câncer e neurobiologia. Na CymitQuimica, oferecemos uma ampla gama de inibidores de sinalização do citoesqueleto de alta qualidade para apoiar sua pesquisa nessas áreas.
Foram encontrados 1382 produtos de "Sinalização Citoesquelética"
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Myosin V-IN-1
CAS:<p>Myosin V-IN-1: potent, selective Myosin V inhibitor, Ki of 6 μM; hinders actin-activated ATPase by blocking ADP release.</p>Fórmula:C29H26N6O3SPureza:98.64% - 98.64%Cor e Forma:SolidPeso molecular:538.62Cepeginterferon alfa-2b
CAS:<p>Cepeginterferon alfa-2b: pegylated interferon with 20 kDa PEG for HCV, PV, ET research.</p>Cor e Forma:LiquidTubulin inhibitor 50
<p>Tubulin inhibitor 50 (compound 07) is a microtubule protein inhibitor that enhances mitochondrial reactive oxygen species levels. It exhibits anticancer activity in HeLa cells with an IC50 value of 0.46 μM, while showing low toxicity in normal cell lines.</p>Fórmula:C16H10ClFN2O2Cor e Forma:SolidPeso molecular:316.04148DSPE-PEG5000-cRGD
<p>DSPE-PEG5000-cRGD is a PEG compound composed of DSPE and an αvβ3 targeting peptide (cRGD). The cRGD peptide has the ability to specifically bind to the αvβ3 present on the surfaces of numerous cancer cells and new vascular cells. DSPE-PEG5000-cRGD is useful for drug delivery applications.</p>Cor e Forma:Odour SolidBimosiamose
CAS:<p>Bimosiamose has anti-inflammatory effects[1].</p>Fórmula:C46H54O16Pureza:98%Cor e Forma:SolidPeso molecular:862.91hAChE-IN-1
<p>hAChE-IN-1 (Compound 24) is a potent inhibitor of human acetylcholinesterase (hAChE), exhibiting an inhibition concentration half-maximum (IC50) of 1.09 μM.</p>Fórmula:C22H24N4OCor e Forma:SolidPeso molecular:360.45SNIPER(ABL)-013
<p>SNIPER(ABL)-013, a compound that links GNF5 (ABL inhibitor) with Bestatin (IAP ligand) via a linker, effectively reduces BCR-ABL protein levels with a DC50 of</p>Fórmula:C42H52F3N7O8Pureza:98%Cor e Forma:SolidPeso molecular:839.9SRI 37892
CAS:<p>SRI 37892 is a Fzd7 inhibitor with potent activities against Wnt/β-catenin signaling and cancer cell viability.</p>Fórmula:C26H19N5O2SPureza:99.93%Cor e Forma:SolidPeso molecular:465.53187-1, N-WASP inhibitor
CAS:<p>Inhibits N-WASP by stabilizing its autoinhibited form, blocking PIP2-induced actin assembly (IC50 ~2 μM), not directly affecting actin polymerization.</p>Fórmula:C96H122N18O16Pureza:98%Cor e Forma:SolidPeso molecular:1784.13Tubulin inhibitor 37
<p>Tubulin Inhibitor 37 (Compound 12) effectively impedes tubulin aggregation (IC50 = 1.3 µM) and demonstrates antiproliferative activity against human tumor cell</p>Fórmula:C16H10Cl2N6OCor e Forma:SolidPeso molecular:373.2Tubulin inhibitor 36
<p>Tubulin Inhibitor 36 (Compound 10) serves as a potent novel inhibitor of tubulin polymerization, which consequently induces apoptosis in glioblastoma cells,</p>Fórmula:C16H13ClN6SCor e Forma:SolidPeso molecular:356.83SIAIS100
<p>SIAIS100, a potent BCR-ABL PROTAC degrader, demonstrates a DC50 value of 2.7 nM, highlighting its efficacy.</p>Fórmula:C44H50ClF2N9O5SCor e Forma:SolidPeso molecular:890.44MPC-0767
CAS:<p>MPC-0767, a potent, selective, and orally active hsp90 inhibitor, is the L-alanine ester prodrug of MPC-3100, exhibiting enhanced chemical stability.</p>Fórmula:C26H36BrN7O9S2Cor e Forma:SolidPeso molecular:734.64YS-49 monohydrate
<p>YS-49, a PI3K/Akt activator, curbs RhoA/PTEN; inhibits VSMC growth by inducing HO-1; an isoquinoline alkaloid that stimulates cardiac β-adrenoceptors.</p>Fórmula:C20H22BrNO3Cor e Forma:SolidPeso molecular:404.3JG-258
CAS:<p>JG-258 is an inactive negative control for Hsp70 inhibitors [1] .</p>Fórmula:C20H22ClN3OS3Cor e Forma:SolidPeso molecular:452.06ML 2-23
<p>ML 2-23 is a potent BCR-ABL degrader operating as a PROTAC, exhibiting selective proteasome-dependent degradation of BCR-ABL within leukemia cells [1].</p>Fórmula:C47H53BrCl2N10O7SPureza:98%Cor e Forma:SolidPeso molecular:1052.86Zolbetuximab MMAE
<p>Zolbetuximab MMAE (IMAB362 MMAE) is a compound targeting Claudin 18.2 (CLDN18.2) with anti-cancer activity, used in the study of gastric and pancreatic cancers.</p>Pureza:95% - 95%Cor e Forma:LiquidPeso molecular:150 kDaProtein Kinase C (19-36)
CAS:<p>Protein Kinase C (19-36) is a pseudosubstrate peptide inhibitor of protein kinase C (PKC), with an IC50 of 0.18 μM.</p>Fórmula:C93H159N35O24Pureza:98%Cor e Forma:SolidPeso molecular:2151.48Orbofiban acetate
CAS:<p>Orbofiban Acetate is a compound that serves as an antagonist to the platelet GPIIb/IIIa receptor, effectively inhibiting platelet aggregation when administered</p>Fórmula:C19H27N5O6Cor e Forma:SolidPeso molecular:421.45Integrin Binding Peptide
CAS:<p>Integrin Binding Peptide, derived from fibronectin, holds the potential as an essential component for preparing PEG hydrogels.</p>Fórmula:C42H63N15O16SCor e Forma:SolidPeso molecular:1066.12
