Sinalização Citoesquelética
Os inibidores de sinalização do citoesqueleto são compostos que interrompem as vias de sinalização que regulam o citoesqueleto, crucial para a forma celular, motilidade, divisão e transporte intracelular. Esses inibidores são usados para estudar a dinâmica das proteínas do citoesqueleto, como actina e tubulina, e seu papel em processos como migração celular, adesão e metástase do câncer. Os inibidores de sinalização do citoesqueleto são valiosos na pesquisa em biologia celular, câncer e neurobiologia. Na CymitQuimica, oferecemos uma ampla gama de inibidores de sinalização do citoesqueleto de alta qualidade para apoiar sua pesquisa nessas áreas.
Foram encontrados 1382 produtos de "Sinalização Citoesquelética"
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DOTA-cyclo(RGDfK)
CAS:<p>DOTA-cyclo(RGDfK) is a and DOTA-like chelator peptide,the αvβ3 integrin receptor ,radionuclide coupled compounds RDCs cancer diagnostics and therapy.</p>Fórmula:C43H67N13O14Cor e Forma:SoildPeso molecular:990.07Tonabersat
CAS:<p>Tonabersat (SB-220453) is a novel and orally available gap-junction modulator and CSD (Cortical spreading depression) inhibitor that,migraine and epilepsy.</p>Fórmula:C20H19ClFNO4Pureza:99.49%Cor e Forma:SolidPeso molecular:391.82SY-LB-35
CAS:<p>SY-LB-35 is a potent BMP receptor agonist enhancing cell growth and viability in C2C12, affecting cell cycle and signaling pathways.</p>Fórmula:C15H11N3OCor e Forma:SolidPeso molecular:249.27Blinatumomab
CAS:<p>Blinatumomab (AMG-10,MT-103) is a CD19/CD3 bispecific B-cell and T-cell binding antibody that in acute lymphoblastic leukemia and non-Hodgkin's lymphoma.</p>Cor e Forma:LiquidKinesore
CAS:<p>Kinesore is a cell-permeable modulator that binds to the microtubule motor protein kinesin-1, thereby inhibiting the interaction between KLC2 and SKIP.</p>Fórmula:C20H16Br2N4O4Pureza:97.24%Cor e Forma:SolidPeso molecular:536.17Ombrabulin hydrochloride
CAS:<p>Ombrabulin hydrochloride is a synthetic, selective CA-4 phosphate ester or derivative of Ombrabulin to disrupt the tubulin cytoskeleton of endothelial cells and</p>Fórmula:C21H27ClN2O6Pureza:98%Cor e Forma:SolidPeso molecular:438.9(±)-1,2-Diolein
CAS:<p>(±)-1,2-Diolein (1,2-Dioleoyl-rac-glycerol) (1,2-Dioleoyl-rac-glycerol) is a PKC activator. (±)-1,2-Diolein could increases myotubes Ca 2+ influx.</p>Fórmula:C39H72O5Cor e Forma:SolidPeso molecular:620.99MK-0429
CAS:<p>MK-0429 is an orally active, selective, and nonpeptide antagonist of αvβ3 integrin (IC50: 80 nM).</p>Fórmula:C23H29N5O4Cor e Forma:SolidPeso molecular:439.51xStAx-VHLL TFA
<p>xStAx-VHLL TFA is a β-catenin degrader formed by coupling xStAx to VHL ligand, with anti-cancer activity and inhibition of Wnt signaling.</p>Fórmula:C154H244N48O29·xC2HF3O2Pureza:99.84%Cor e Forma:SolidPeso molecular:3231.89 (free base)Avanbulin
CAS:<p>Avanbulin hinders tubulin polymerization, has unique antitumor properties, and is effective against various human tumors at low concentrations.</p>Fórmula:C20H17N7O2Cor e Forma:SolidPeso molecular:387.39AZ82
CAS:<p>AZ82 is an inhibitor of the kinesin-like protein KIFC1, which induces multipolar mitosis and apoptosis in prostate cancer cells.</p>Fórmula:C28H31F3N4O3SPureza:99.31%Cor e Forma:SolidPeso molecular:560.63Cilengitide TFA
CAS:<p>Cilengitide, αvβ3/αvβ5 inhibitor, IC50: 4.1/79 nM in vitro. 10x selectivity vs. gpIIbIIIa. Phase 2.</p>Fórmula:C29H41F3N8O9Cor e Forma:SolidPeso molecular:702.68PU-H71
CAS:<p>PU-H71 is an effective selective HSP90 inhibitor with an IC50 of 51 nM.</p>Fórmula:C18H21IN6O2SPureza:98.31% - 99.937%Cor e Forma:SolidPeso molecular:512.37Danegaptide
CAS:<p>Danegaptide (GAP-134) is a potent, second-gen, oral gap junction modifier; a small modified dipeptide.</p>Fórmula:C14H17N3O4Cor e Forma:SolidPeso molecular:291.3GW406108X
CAS:<p>GW406108X is a Kif15 and ULK1 inhibitor; IC50: 0.82 µM (ATPase), pIC50: 6.37; blocks autophagy.</p>Fórmula:C20H11Cl2NO4Pureza:98%Cor e Forma:SolidPeso molecular:400.21Ipfencarbazone
CAS:<p>Ipfencarbazone herbicide agent, is a substance being developed for the control of weeds such as watergrass in rice.</p>Fórmula:C18H14Cl2F2N4O2Cor e Forma:SolidPeso molecular:427.23Combretastatin A-1
CAS:<p>Combretastatin A-1 is a microtubule inhibitor with anti-tumour and can be used to study liver cancer.</p>Fórmula:C18H20O6Pureza:97.49% - 97.49%Cor e Forma:SolidPeso molecular:332.35Debio 0932
CAS:<p>Debio 0932 (CUDC-305) is a Hsp9 inhibitor, apoptosis, and has the advantage of being orally available and cross the BBB for cancers NSCLC and neuroblastoma.</p>Fórmula:C22H30N6O2SPureza:98.98%Cor e Forma:SolidPeso molecular:442.58CCT245232
CAS:<p>CCT245232 is a potent HSF1 inhibitor, possibly used for researching cancer.</p>Fórmula:C27H23N3O4Cor e Forma:SolidPeso molecular:453.49Asciminib hydrochloride
CAS:<p>Asciminib (ABL001) hydrochloride is a selective and potent mutant BCR-ABL1 inhibitor that inhibits Ba/F3 cell growth (IC50: 0.25 nM).</p>Fórmula:C20H19Cl2F2N5O3Cor e Forma:SolidPeso molecular:486.3Trifluralin
CAS:<p>Trifluralin (Treflan) is an agricultural herbicide with mild toxicity. Trifluralin is a novel pollutant that can interfere with mitochondrial respiration.</p>Fórmula:C13H16F3N3O4Pureza:99.84%Cor e Forma:Yellow-Orange Crystalline SolidPeso molecular:335.28PKC-θ inhibitor
CAS:<p>PKC-theta inhibitor is PKC-θinhibitor, with an IC50 of 12 nM.</p>Fórmula:C20H25F3N6O3Pureza:99.46%Cor e Forma:SolidPeso molecular:454.45Amiprofos methyl
CAS:<p>Amiprofos methyl (BAY-NTN 6867) is an organophosphorus herbicide that specifically and competitively inhibits microtubule polymerization in plant cells.</p>Fórmula:C11H17N2O4PSPureza:99.66%Cor e Forma:SolidPeso molecular:304.30Palmitic acid-1-13C
CAS:<p>Palmitic acid-13C, a 16-C saturated fatty acid internal standard for GC/LC-MS, is prevalent in plasma lipids and influences protein acylation and COX-2 levels.</p>Fórmula:C16H32O2Cor e Forma:SolidPeso molecular:257.422NSC305787 hydrochloride
CAS:<p>NSC305787 hydrochloride ((Rac)-NSC305787 hydrochloride is a Cdc25 dual specificity phosphatase and EZR inhibitor with antitumor activity and inhibits Cdc25B2.</p>Fórmula:C25H31Cl3N2OPureza:99.07% - 99.07%Cor e Forma:SolidPeso molecular:481.89BSc3094
CAS:<p>BSc3094 is a potent Tau aggregation inhibitor that demonstrates the potential for Alzheimer's disease (AD) research.</p>Fórmula:C17H12N6O3SCor e Forma:SolidPeso molecular:380.38Latrunculin A
CAS:<p>Latrunculin A, a toxin from the sponge Latrunculia magnifica, binds and inhibits actin polymerization (Kds: 0.1-4.7 μM).</p>Fórmula:C22H31NO5SPureza:98%Cor e Forma:Waxy SolidPeso molecular:421.55Ulacamten
CAS:<p>Ulacamten is an effective inhibitor of cardiac myosin (cardiacmyosin).</p>Fórmula:C21H25F2N3O3Cor e Forma:SolidPeso molecular:405.44ADH-1
CAS:<p>ADH-1 (Exherin) is an N-cadherin antagonist, inhibits N-cadherin mediated cell adhesion with potential antineoplastic and antiangiogenic activities.</p>Fórmula:C22H34N8O6S2Pureza:99.94%Cor e Forma:SolidPeso molecular:570.69GPRP
CAS:<p>GPRP (Gly-Pro-Arg-Pro) is a fibrin polymerization inhibitor.</p>Fórmula:C18H31N7O5Cor e Forma:White To Off-White PowderPeso molecular:425.48TTBK1-IN-1
CAS:<p>TTBK1-IN-1 (compound 31) is a potent and selective TTBK1 inhibitor with CNS penetration that inhibits tau phosphorylation , Alzheimer's disease.</p>Fórmula:C18H19N5O2Cor e Forma:SolidPeso molecular:337.38colchiceine
CAS:<p>colchiceine has a wide range of applications in life science related research.</p>Fórmula:C21H23NO6Pureza:99.38%Cor e Forma:SolidPeso molecular:385.41Anti-Mouse CD3 Antibody (17A2)
<p>Anti-Mouse CD3 Antibody (17A2) is an IgG2b class antibody of murine origin targeting CD3 and can be used to study TCR signaling and antigen recognition.</p>Cor e Forma:Odour LiquidPhosTAC7
CAS:<p>PhosTAC7 successfully induced ternary protein complex formation of Halo-FOXO3a in a dose-dependent manner.</p>Fórmula:C58H87ClN2O17Pureza:98.96%Cor e Forma:SolidPeso molecular:1119.77Protein kinase inhibitor H-7 dihydrochloride
CAS:<p>Protein kinase inhibitor H-7 dihydrochloride(H-7 dihydrochloride) is a potent protein kinase C (PKC) inhibitor.</p>Fórmula:C14H19Cl2N3O2SPureza:99.54%Cor e Forma:White Crystalline SolidPeso molecular:364.29RGD Trifluoroacetate
CAS:<p>RGD Trifluoroacetate is a tripeptide for cell adhesion, effective on 24 integrins, and widely used for synthetic surface binding.</p>Fórmula:C14H23F3N6O8Pureza:98%Cor e Forma:SoildPeso molecular:460.36Yoda 1
CAS:<p>Yoda 1 is an agonist of the Piezo1 channel that agonizes human- and mouse-derived Piezo1. Yoda 1 is also an inhibitor of GlyT2. Cost-effective, quality assurance.</p>Fórmula:C13H8Cl2N4S2Pureza:98% - 99.98%Cor e Forma:SolidPeso molecular:355.27ILK-IN-2
CAS:<p>ILK-IN-2 (OSU-T315) is a novel potent, orally active ILK (integrin-linked kinase) inhibitor with IC50 of 0.6 μM.</p>Fórmula:C30H30F3N5OPureza:99.30%Cor e Forma:SolidPeso molecular:533.59PKC ζ pseudosubstrate acetate
<p>PKC ζ pseudosubstrate acetate is an inhibitor of protein kinase C (PKC) ζ; attached to cell permeabilisation Antennapedia domain vector peptide.</p>Fórmula:C78H132N30O18Pureza:98.78%Cor e Forma:SolidPeso molecular:1778.10Fingolimod hydrochloride
CAS:<p>Fingolimod hydrochloride (FTY720) , a novel immune modulator, is a sphingosine 1-phosphate (S1P) antagonist (IC50: 0.033 nM in K562 and NK cells).</p>Fórmula:C19H34ClNO2Pureza:99.26% - 99.83%Cor e Forma:White SolidPeso molecular:343.93H-Gly-Arg-Gly-Asp-Asn-Pro-OH
CAS:<p>RGD peptide (GRGDNP) (RGD peptide GRGDNP(2TFA)) is a integrin-ligand interactions inhibitor.</p>Fórmula:C23H38N10O10Pureza:>99.99%Cor e Forma:SolidPeso molecular:614.61Valrubicin
CAS:<p>Valrubicin (AD-32) (AD 32) inhibits TPA- and PDBu-induced PKC activation (IC50s: 0.85 and 1.25 μM) and has antitumor and anti-inflammatory activity.</p>Fórmula:C34H36F3NO13Pureza:98.63%Cor e Forma:SolidPeso molecular:723.64E7820
CAS:<p>E7820 (ER68203-00) is an angiogenesis inhibitor by suppressing integrin a2 (a cell adhesion molecule expressed on endothelial cells).</p>Fórmula:C17H12N4O2SPureza:98.31% - 99.11%Cor e Forma:SolidPeso molecular:336.37AG957
CAS:<p>Tyrphostin AG957, a tyrosine kinase inhibitor with anti-BCR/ABL tyrosine kinase activity restores beta1 integrin-mediated adhesion and inhibitory signaling in</p>Fórmula:C15H15NO4Pureza:98.82%Cor e Forma:SolidPeso molecular:273.28Doxepin
CAS:<p>Doxepin: tricyclic antidepressant, inhibits serotonin/norepinephrine reuptake, helps atopic dermatitis/urticaria, cognitive protector, anti-inflammatory.</p>Fórmula:C19H21NOCor e Forma:SolidPeso molecular:279.38Orbofiban
CAS:<p>Orbofiban, an orally administered antagonist of the platelet GPIIb/IIIa receptor, effectively inhibits platelet aggregation.</p>Fórmula:C17H23N5O4Cor e Forma:SolidPeso molecular:361.4Eptifibatide acetate (148031-34-9 free base)
CAS:<p>Eptifibatide acetate (148031-34-9), a cyclic heptapeptide GP IIb/IIIa inhibitor antiplatelet drug.</p>Fórmula:C35H49N11O9S2·xC2H4O2Pureza:99.7% - 99.87%Cor e Forma:SolidPeso molecular:831.96 (free base)Valecobulin
CAS:<p>Valecobulin is a potent β-tubulin polymerization inhibitor. Valecobulin is a valine prodrug of (S516) and an avascular disrupting compound.</p>Fórmula:C26H28N6O5SPureza:98%Cor e Forma:SolidPeso molecular:536.6Questiomycin A
CAS:<p>Questiomycin A: crème fraiche antibiotic with antibacterial, anticancer effects; inhibits GRP78.</p>Fórmula:C12H8N2O2Pureza:98.13% - 98.7%Cor e Forma:SolidPeso molecular:212.2Albendazole sulfoxide
CAS:<p>Albendazole sulfoxide (Ricobendazole) is a metabolite of Albendazole, an anthelmintic.</p>Fórmula:C12H15N3O3SPureza:97.29%Cor e Forma:White To Off-White PowderPeso molecular:281.33
