Cetonas e Derivados
As cetonas são compostos orgânicos que contêm um grupo carbonilo (C=O) ligado a dois átomos de carbono, formando uma estrutura onde o grupo carbonilo é flanqueado por grupos alquila ou arila. Na farmacologia, as cetonas são utilizadas na formulação de APIs devido à sua capacidade de melhorar a solubilidade e a estabilidade dos princípios ativos. Algumas cetonas possuem propriedades anti-inflamatórias, analgésicas e antimicrobianas. Os derivados de cetonas incluem compostos nos quais o grupo carbonilo é modificado, como os enóis, que têm aplicações na síntese de fármacos e como intermediários químicos na produção de outros compostos bioativos. Os derivados de cetonas são utilizados no desenvolvimento de novos medicamentos, incluindo aqueles para o tratamento de doenças neurodegenerativas, distúrbios metabólicos e certos tipos de câncer, devido aos seus efeitos específicos sobre enzimas e processos celulares.
Foram encontrados 2393 produtos de "Cetonas e Derivados"
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4-Acetaminophen Sulfate Potassium Salt
CAS:Produto ControladoFórmula:C8H8NO5S·KCor e Forma:BeigePeso molecular:269.32Quininone
CAS:<p>Applications Quininone has been shown to have antimalarial activity in mice. Quininone has been shown to aid the binding of drug-induced antibodies to human platelets.<br>References Klayman, D.L., et. al.: J. Med. Chem., 16, 1042 (1973); Christie, D.J., et. al.: J. Lab. Clin. Med., 104, 730 (1984)<br></p>Fórmula:C20H22N2O2Cor e Forma:White To Light BeigePeso molecular:322.403-Benzoyl-α-methylbenzeneacetonitrile
CAS:<p>Impurity Ketoprofen EP Impurity F; Ketoprofen USP Related Compound F<br>Applications 3-Benzoyl-α-methylbenzeneacetonitrile (Ketoprofen EP Impurity F; Ketoprofen USP Related Compound F) was used as a substrate to study the enantioselectivity of nitrile hydratase from Rhodococcus equi A4.<br>References Martinkova, L., et al.: Biotechnol. Lett. 18, 1073 (1996); Layh, N., et al.: Botehcnol. Lett. 17, 187 (1995);<br></p>Fórmula:C16H13NOCor e Forma:WhitePeso molecular:235.286-Methoxy-2-naphthaleneacetic Acid-d3 (Desmethyl Naproxen-d3)
CAS:Produto Controlado<p>Applications A labelled metabolite of Nabumetone (N200500). A competitive, non-selective COX inhibitor.<br>References Turpeinen et. al.: Drug Metabolism and Dispositoin, 37: 1017 (2009); Daniels, F., et al.: J. Invest. Dermatol., 44, 259 (1965), Bosca, F., et al.: Photochem. Photobiol., 71, 173 (2000),<br></p>Fórmula:C13H9D3O3Cor e Forma:White To Off-WhitePeso molecular:219.253-Cysteinylacetaminophen-D5 (major), Trifluoroacetic Acid Salt
CAS:Produto Controlado<p>Applications 3-Cysteinylacetaminophen-D5 (major), Trifluoroacetic Acid Salt is deuterium labeled 3-Cysteinylacetaminophen Trifluoroacetic Acid Salt (C994750), which is a metabolite of Acetaminophen (A161220), an analgesic and antipyretic agent used as a pain reliever to treat headache, muscle aches, and arthritis (1,2,3).Minimum isotopic incorporation d-3, no d-0 present. A representative lot has 64% isotopic incorporation at the 6-position, 89% at the 4-position.<br>References (1) McGill, M. R. and Jaeschke, H. Pharm Res. 30, 2174 (2013)(2) Fairbrother, J.E., et al.: Anal. Profiles Drug Subs., 3, 1 (1974) (3) Hinson, J.A., et al.: Rev. Biochem. Toxicol., 2, 103 (1980)<br></p>Fórmula:C11H9D5N2O4S•C2HF3O2Cor e Forma:NeatPeso molecular:389.36Acetaminophen-d4 (major)
CAS:Produto Controlado<p>Applications Acetaminophen-d4 (major) is deuterium labeled Acetaminophen (A161220), an analgesic and antipyretic agent used as a pain reliever to treat headache, muscle aches, and arthritis (1,2,3).<br>References (1) McGill, M. R. and Jaeschke, H. Pharm Res. 30, 2174 (2013)(2) Fairbrother, J.E., et al.: Anal. Profiles Drug Subs., 3, 1 (1974)(3) Hinson, J.A., et al.: Rev. Biochem. Toxicol., 2, 103 (1980)<br></p>Fórmula:C82H4H5NO2Cor e Forma:Off-WhitePeso molecular:155.19(-)-Tramadol Hydrochloride
CAS:Produto Controlado<p>Stability Hygroscopic<br>Applications An analgesic. Used in the treatment of urinary incontinence.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Raffa, R.B., et al.: J. Pharmacol. Exp. Ther., 267, 331 (1993)<br></p>Fórmula:C16H25NO2·ClHCor e Forma:NeatPeso molecular:299.84Niflumic Acid-d5 (Major)
CAS:Produto Controlado<p>Applications Anti-inflammatory. Selective cyclooxygenase-2 (COX-2) inhibitor.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Glasson, et al.: Biochem, Pharmacol., 18, 633 (1969), Boissier, et al.: Therapie, 26, 211 (1971), Sorenson, J.R.J., et al.: J. Med. Chem., 19, 135 (1976), Barnett, J., et al.: Biochim. Biophys. Acta, 1209, 130 (1994), Johnson, J.L., et al.: Arch. Biochem. Biophys., 324, 26 (1995),<br></p>Fórmula:C13H4D5F3N2O2Cor e Forma:NeatPeso molecular:287.25Acetaminophen Mercapurate Disodium
CAS:<p>Applications Acetaminophen Mercapurate Disodium Salt is a metabolite of Acetaminophen (A161220), an analgesic and antipyretic agent used as a pain reliever to treat headache, muscle aches, and arthritis (1,2).<br>References (1) McGill, M. R. and Jaeschke, H. Pharm Res. 30, 2174 (2013)(2) Potter, D.W. et al.: Mol. Pharmacol., 29, 155 (1986)<br></p>Fórmula:C13H14N2O5S·2NaCor e Forma:NeatPeso molecular:356.31α-(4-Isobutylphenyl)ethanol
CAS:<p>Applications The photodegradation product of Ibuprofen (I140000). Shows cytotoxicity activity.<br>References Kobayashi, S., et al.: Biochemistry, 23, 4589 (1984), Karthein, R., et al.: Eur. J. Biochem., 171, 313 (1988), Maranon, M., et al.: Phytochem., 37, 1217 (1994),<br></p>Fórmula:C12H18OCor e Forma:Colourless LiquidPeso molecular:178.27m-Isobutyl Ibuprofen
CAS:<p>Impurity Ibuprofen EP Impurity A<br>Applications m-Isobutyl Ibuprofen (Ibuprofen EP Impurity A) is an Ibuprofen (I140000) impurity used in the study of potent noncompetitive interleukin-8 inhibitors.<br>References Moriconi, A. et al.: J. Med. Chem., 50, 3984 (2007); Allegretti, M. et al.: J. Med. Chem., 48, 4312 (2005);<br></p>Fórmula:C13H18O2Cor e Forma:NeatPeso molecular:206.281-[3-(6-bromo-2H-1,3-benzoxazin-3(4H)-yl)phenyl]ethanone
CAS:Pureza:95.0%Peso molecular:332.1969909667969(3-Benzoylphenyl)acetonitrile
CAS:<p>Impurity Ketoprofen EP Impurity I<br>Applications (3-Benzoylphenyl)acetonitrile (Ketoprofen EP Impurity I) is a Ketoprofen intermediate.<br>References Allais, A., et al.: Eur. J. Med. Chem., 9, 381 (1974).<br></p>Fórmula:C15H11NOCor e Forma:Colourless To Light YellowPeso molecular:221.253-(N-Acetyl-L-cystein-S-yl) Acetaminophen
CAS:Produto Controlado<p>Stability Very Hygroscopic<br>Applications Paracetamol Mercapturate is a metabolite of Acetaminophen (A161220) (1,2). Acetaminophen is a widely used analgesic and antipyretic drug. It can also be used in biological study of urinary antihypertensive drug metabolite screening using molecular networking coupled to high-resolution mass spectrometry fragmentation.<br>References (1) Trettin, A., et al.: J. Chromatogr. B., 963, 105 (2014) (2) Pickering, G., et al.: Clin. Pharmacol. Ther., 90, 707 (2011)<br></p>Fórmula:C13H16N2O5SCor e Forma:NeatPeso molecular:312.344'-Methylacetophenone
CAS:Produto Controlado<p>Impurity Celecoxib Impurity<br>Applications 4'-Methylacetophenone is a methylated acteophenone used in cosmetics and perfumery. The presence of 4'-Methylacetophenone has been shown to accelerate the photopolymerization of Methyl methacrylate.<br>References Dwivedi, U.N. et al.: Acta Polym., 39, 596 (1988); Opdyke, D.L.J. et al.: Food Cosm. Toxicol., 12, 933 (1974);<br></p>Fórmula:C9H10OCor e Forma:NeatPeso molecular:134.18rac-Acetaminophen Mercapturate-d5 (Major)
CAS:Produto Controlado<p>Applications rac-Acetaminophen Mercapturate-d5 (Major), is a labeled analogue and free acid of 3-(N-Acetyl-L-cystein-S-yl) Acetaminophen Disodium Salt (A172100), which is a metabolite of Acetaminophen (A161220). Acetaminophen is an analgesic and antipyretic agent used as a pain reliever to treat headache, muscle aches, and arthritis (1,2,3).<br>References van der Hooft, J.,et al.: Metabolomics, 12, 1 (2016)<br></p>Fórmula:C13H11D5N2O5SCor e Forma:NeatPeso molecular:317.375-[1-(2,3-Dimethylphenyl)ethenyl]-1H-imidazole
CAS:Produto ControladoFórmula:C13H14N2Cor e Forma:NeatPeso molecular:198.26Propyphenazone
CAS:Produto Controlado<p>Applications Analgesic; antipyretic; anti-inflammatory.<br>References Ertl, P., et al.: J. Med. Chem., 43, 3714 (2000), Sun, C., et al.: J. Pharm. Sci., 93, 646 (2004),<br></p>Fórmula:C14H18N2OCor e Forma:NeatPeso molecular:230.314-Chlorobenzoic Acid
CAS:Produto Controlado<p>Impurity Acemetacin EP Impurity A / Bezafibrate EP Impurity B<br>Applications A benzoic acid analogue that showed antifungal activity against strains of Aspergillus flavus, Aspergillus fumigatus and Aspergillus terreus, causative agents of human aspergillosis, in in vitro bioassays. It is used as a preservative.<br>References Rep, M., et al.: J. Biol. Chem., 275, 8290 (2000), Jaeger, T., et al.: Biofactors, 27, 109 (2006), Kim, J., et al.: Fungal Biology, 114, 817 (2010),<br></p>Fórmula:C7H5ClO2Cor e Forma:White To Off-WhitePeso molecular:156.571-(2-(CYCLOPROPYLMETHOXY)-6-(4-METHOXYBENZYLOXY)PHENYL)ETHANONE
CAS:Pureza:95.0%Peso molecular:326.3919982910156p-Phenetidine-d5 Hydrochloride
CAS:Produto Controlado<p>Applications Labelled p-Phenetidine (P296300). A toxic metabolite of Phenacetin (P294580) which exhibits high renal toxicity. p-Phenetidine also reduced COX-1 and COX-2 expression in neutrophils.<br>References Green, C., et al.: Br. Med. J., 1, 162 (1969), Nelson, S., et al.: J. Med. Chem., 25, 753 (1982), Nicholls, A., et al.: Xenobiotica, 27, 1175 (1997),<br></p>Fórmula:C8H7D5ClNOCor e Forma:NeatPeso molecular:178.67Nordihydrocapsaicin
CAS:Produto Controlado<p>Applications Nordihydrocapsaicin is a capsaicinoid and analog and congener of capsaicin in chili peppers.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Iwai, K., et al.: Agri. Biol. Chem., 43, 2493 (1979); Kozukue, N., et al.: J. Agr. Food Chem., 53, 9172 (2005)<br></p>Fórmula:C17H27NO3Cor e Forma:Off-WhitePeso molecular:293.404′-(4-Fluorophenoxy)acetophenone
CAS:Fórmula:C14H11FO2Pureza:97%Cor e Forma:SolidPeso molecular:230.238Dihydro Ketoprofen (Mixture of Diastereomers)
CAS:<p>Applications A metabolite of Ketoprofen.<br>References Jamali, F., et al.: J. Pharma. Sci., 79, 460 (1990), Lindon, J., et al.: Drug Metab. Rev., 29, 705 (1997), Akira, K., et al.: Drug Metab. Dispos., 26, 457 (1998), Rudy, A., et al.: J. Clin. Pharmacol., 38, 3S (1998),<br></p>Fórmula:C16H16O3Cor e Forma:NeatPeso molecular:256.30Dihydro Capsaicin
CAS:Produto Controlado<p>Applications Capsaicin (C175680) analog. A VR1 vaniloid receptor agonist.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Ralevic, V., et al.: Biochem. Pharmacol., 65, 143 (2003), Thompson, R., et al.: Anal. Bioanal. Chem., 381, 1432 (2005), Tuoya., et al.: Life Sci., 78, 1515 (2006),<br></p>Fórmula:C18H29NO3Cor e Forma:White To Off-WhitePeso molecular:307.434-Acetaminophen-d3 Sulfate Potassium Salt
CAS:Produto Controlado<p>Applications 4-Acetaminophen-d3 Sulfate Potassium Salt is a deuterium labeled metabolite of Acetaminophen (A161220) (1,2,3).<br>References (1) Lloyd, A., et al.: Biochim. Biophys. Acta., 52, 413 (1961)(2) Purohit, A., et al.: J. Steroid Biochem. Mol. Biol., 86, 423 (2003) (3) Winum, J., et al.: J. Med. Chem., 46, 2197 (2003)<br></p>Fórmula:C8H5D3KNO5SCor e Forma:NeatPeso molecular:272.33p-Ethylhydratropic Acid
CAS:<p>Impurity Ibuprofen EP Impurity N<br>Applications p-Ethylhydratropic Acid (Ibuprofen EP Impurity N) is a phenylacetic acid with potential antiinflammatory activities. p-Ethylhydratropic Acid is an impurity of Ibuprofen (I140000).<br></p>Fórmula:C11H14O2Cor e Forma:WhitePeso molecular:178.231-(4-{3-[4-(6-fluoro-1,2-benzoxazol-3-yl)piperidin-1-yl]propoxy}-3-methoxyphenyl)ethan-1-one
CAS:Pureza:97.0%Peso molecular:426.4880065917969Medetomidine-13C,d3 Hydrochloride
CAS:Produto Controlado<p>Applications Labelled α2-adrenergic agonist. Sedative; analgesic.<br>References Scheinin, M., et al.: Br. J. Clin. Pharmacol., 24, 443 (1987), Stenberg, D., et al.: J. Vet. Pharmacol. Ther., 10, 319 (1987), Virtanen, R., et al.: Eur. J. Pharmacol., 150, 9 (1988), Cullen, L.K., et al.: Br. Vet. J., 152, 519 (1996),<br></p>Fórmula:CC122H3H13N2·ClHCor e Forma:White To Light YellowPeso molecular:240.75rac α-Hydroxy Ibuprofen
CAS:Produto Controlado<p>Impurity Ibuprofen EP Impurity M<br>Applications A potential precursor of Ibuprofen and Naproxen. Antiinflammatory agent.<br>References Williams, K., et al.: Pharm. Ther., 46, 273 (1990), Evans, A., et al.: Eur. J. Clin. Pharmacol., 42, 237 (1992), Tucker, G., et al.: Lancet, 355, 1085 (2000), Tan, S., et al.: Xenobiotica, 32, 683 (2002), Fura, A., et al.: J. Pharm. Biomed. Anal., 32, 513 (2003),<br></p>Fórmula:C13H18O3Cor e Forma:White To Off-WhitePeso molecular:222.28rac Ketorolac
CAS:Produto Controlado<p>Applications Ketorolac is an analgesic; anti-inflammatory.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Etman, M., et al.: Pharm. Technol., 32, 58 (2008), Chelladurai, S., et al.: Chem. Pharm. Bull., 56, 1596 (2008), Sanderson, H., et al.: Toxicol. Lett., 187, 84 (2009),<br></p>Fórmula:C15H13NO3Cor e Forma:Off White SolidPeso molecular:255.274′-Methoxyacetophenone
CAS:Fórmula:C9H10O2Pureza:99.0%Cor e Forma:Solid, White crystallinePeso molecular:150.177N-Acetyl-4-benzoquinone Imine
CAS:Produto Controlado<p>Stability Air Sensitive, Light Sensitive, Moisture Sensitive, Temperature Sensitive<br>Applications N-Acetyl-4-benzoquinone Imine (NAPQI) is a toxic metabolite of Acetaminophen (A161220), an analgesic and antipyretic agent used as a pain reliever to treat headache, muscle aches, and arthritis (1,2,3). N-Acetyl-4-benzoquinone Imine can react with cysteine residues of hepatic proteins to yield Acetaminophen-cysteine (A161255) (4).<br>References (1) Jaeschke, H., et al.: Toxicol. Sci., 89, 31 (2006) (2) O’Malley G. F., et al.: J Med Toxicol. 11, 317 (2015)(3) McGill, M. R. and Jaeschke, H. Pharm Res. 30, 2174 (2013)(4) Frey, S. M., et al.: J Med Toxicol. 11, 218 (2015)<br></p>Fórmula:C8H7NO2Cor e Forma:NeatPeso molecular:149.152-Butyl-6-methoxynaphthalene
CAS:Produto Controlado<p>Applications 2-Butyl-6-methoxynaphthalene is an impurity of Nabumetone (N200500), an anti-inflammatory and antibacterial agent.<br>References Najera, C., et al.: Adv. Syn. Cat., 346, 1798 (2004); Kumpulainen, H., et al.: J. Med. Chem., 49, 1207 (2006)<br></p>Fórmula:C15H18OCor e Forma:White To GreyPeso molecular:214.34-Acetaminophen-d3 Sulfate
CAS:Produto Controlado<p>Applications 4-Acetaminophen-d3 Sulfate is deuterium labeled metabolite of Acetaminophen (A161220), an analgesic and antipyretic agent (1,2,3).<br>References (1) Lloyd, A., et al.: Biochim. Biophys. Acta., 52, 413 (1961) (2) Purohit, A., et al.: J. Steroid Biochem. Mol. Biol., 86, 423 (2003) (3) Winum, J., et al.: J. Med. Chem., 46, 2197 (2003)<br></p>Fórmula:C82H3H6NO5SCor e Forma:White To Off-WhitePeso molecular:234.241-(2,3-Dimethylphenyl)ethyl Chloride
CAS:Produto Controlado<p>Applications 1-(2,3-Dimethylphenyl)ethyl Chloride is an impurity of Medetomidine (M203250), an α2-Adrenergic agonist. Sedative; analgesic.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Scheinin, M., et al.: Br. J. Clin. Pharmacol., 24, 443 (1987), Stenberg, D., et al.: J. Vet. Pharmacol. Ther., 10, 319 (1987), Virtanen, R., et al.: Eur. J. Pharmacol., 150, 9 (1988), Cullen, L.K., et al.: Br. Vet. J., 152, 519 (1996),<br></p>Fórmula:C10H13ClCor e Forma:Clear Colourless To Dark BrownPeso molecular:168.66(R)-Apomorphine b-D-Glucuronide
Produto ControladoFórmula:C23H25NO8Cor e Forma:WhitePeso molecular:443.452,2',5'-Trichloroacetophenone
CAS:Produto Controlado<p>Applications 2,2',5'-Trichloroacetophenone is a useful research chemical for organic synthesis and other chemical processes.<br>References Xu, L., et al.: Chem. Res. Chin. Univ., 24, 299 (2008); Song, W., et al.: MedChemComm, 7, 1441 (2016)<br></p>Fórmula:C8H5Cl3OCor e Forma:NeatPeso molecular:223.48Niflumic Acid
CAS:Produto Controlado<p>Applications Anti-inflammatory. Selective cyclooxygenase-2 (COX-2) inhibitor.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Glasson, et al.: Biochem, Pharmacol., 18, 633 (1969), Boissier, et al.: Therapie, 26, 211 (1971), Sorenson, J.R.J., et al.: J. Med. Chem., 19, 135 (1976), Barnett, J., et al.: Biochim. Biophys. Acta, 1209, 130 (1994), Johnson, J.L., et al.: Arch. Biochem. Biophys., 324, 26 (1995),<br></p>Fórmula:C13H9F3N2O2Cor e Forma:Light YellowPeso molecular:282.223-Methylbenzophenone
CAS:<p>Applications 3-Methylbenzophenone (cas# 643-65-2) is a useful research chemical.<br></p>Fórmula:C14H12OCor e Forma:NeatPeso molecular:196.248-Methylquinoline
CAS:<p>Applications 8-Methylquinoline is used in QSAR treatment of mutagenicity and cytotoxicity of quinolines.<br>References Smith, C. J., et al.: Mutat. Res., Fund. Mol. Mech. Mut., 379, 167 (1997)<br></p>Fórmula:C10H9NCor e Forma:Light Yellow LiquidPeso molecular:143.185rac-Ibuprofen Amide
CAS:Produto Controlado<p>Impurity Ibuprofen EP Impurity C<br>Applications An impurity of Ibuprofen (I140000).<br>References Haikala, V., et al.: J. Pharm. Sci., 80, 456 (1991), Sochor, J., et al.: J. Pharm. Biomed. Anal., 13, 899 (1995),<br></p>Fórmula:C13H19NOCor e Forma:WhitePeso molecular:205.30Acetanilide (Acetylaniline)
CAS:Produto Controlado<p>Impurity Paracetamol EP Impurity D<br>Applications Acetanilide (Acetylaniline) the first aniline derivative found to possess analgesic and antipyretic properties (1,2). It is also an impurity of Acetaminophen (A161220).<br>References (1) Gohil, V., et al.: Nat. Biotechnol., 28, 249 (2010) (2) Chang, C., et al.: J. Nat. Prod., 73, 229 (2010)<br></p>Fórmula:C8H9NOCor e Forma:White To Light BrownPeso molecular:135.16(S)-Ketorolac
CAS:Produto Controlado<p>Applications (S)-Ketorolac is the S-enantiomer of Ketorolac. The (S)-enantiomer is about 60 times more potent than (R)-enantiomer. Prostaglandin biosynthesis inhibitor. Analgesic; anti-inflammatory.<br>References Rooks, W.H., et al.: Agents Actions, 12, 684 (1982), Guzman, A., et al.: J. Med. Chem., 29, 589 (1986), McQuary, H.J., et al.: Clin. Pharmacol. Ther., 39, 89 (1986),<br></p>Fórmula:C15H13NO3Cor e Forma:NeatPeso molecular:255.273-Hydroxy Medetomidine
CAS:Produto Controlado<p>Applications A metabolite of Medetomidine (M203250).<br>References Salonen, J.S., et al.: Xenobiotica, 20, 471 (1990),<br></p>Fórmula:C13H16N2OCor e Forma:NeatPeso molecular:216.28Ketoprofen 1,4-Sorbitan Ester
Produto Controlado<p>Applications Ketoprofen 1,4-Sorbitan Ester is a derivative of Ketoprofen (K200800), an anti-inflammatory; analgesic.<br>References Ueno, K., et al.: J. Med. Chem., 19, 941 (1976), Liversidge, G.G., Anal. Profiles Drug Subs., 10, 443 (1981), Jamali, F., et al.: Clin. Pharmacokinet., 19, 197 (1990),<br></p>Fórmula:C22H24O7Cor e Forma:Off-WhitePeso molecular:400.42Hydroxy Carisoprodol (mixture of diastereomers)
CAS:Produto Controlado<p>Applications Hydroxy Carisoprodol is the metabolite of Carisoprodol (C183580) in equine urine and serum.<br>References Kintz, P., et al.: J. Anal. Toxicol., 17, 408 (1993), Olsen, H., et al.: Ther. Drug Monit., 16, 337 (1994), Reeves, R., et al.: J. Addict. Diseas., 18, 51 (1999),<br></p>Fórmula:C12H24N2O5Cor e Forma:NeatPeso molecular:276.33(-)-(3S)-3-Hydroxy Quinine
CAS:Produto ControladoFórmula:C20H24N2O3Cor e Forma:NeatPeso molecular:340.42Metaxalone-d6
CAS:Produto Controlado<p>Applications It is a muscle relaxant used to relax muscles and relieve pain.<br></p>Fórmula:C122H6H9NO3Cor e Forma:NeatPeso molecular:227.29Bornyl Acetate (Mixture of Diastereomers)
CAS:<p>Applications Bornyl Acetate (Mixture of Diastereomers) is a monoterpene ester, and also the main, natural constituent of valerian root oil. Bornyl acetate also has analgesic and anti-inflammatory properties.<br>References Buchbauer, G., et al.: Die Pharm., 47, 620 (1992); Oh, H., et al.: Appl. Micro., 15, 777 (1967); Wu, X., et al.: J. Chinese Med. Mat., 27, 438 (2004)<br></p>Fórmula:C12H20O2Cor e Forma:NeatPeso molecular:196.29Acemetacin
CAS:Produto Controlado<p>Applications Acemetacin is a non-steroidal anti-inflammatory agent and used to treat rheumatic disease and other musculoskeletal disorders (1,2).<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References (1) Jacobi, H. and Dell, H. D.: Arzneimittelforschung 30, 1398 (1980) (2) Moore, R. A., et al.: Cochrane Database Syst Rev. 8,CD007589 (2009)<br></p>Fórmula:C21H18ClNO6Cor e Forma:YellowPeso molecular:415.82rac Ketoprofen Amide
CAS:Produto Controlado<p>Applications An amide of Ketoprofen (K200800) with anti-inflammatory properties.<br>References Spickett, R.G.W. et al.: Eur. J. Med. Chem., 11, 7 (1976); Ueno, K., et al.: J. Med. Chem., 19, 941 (1976); Liversidge, G.G., Anal. Profiles Drug Subs., 10, 443 (1981);<br></p>Fórmula:C16H15NO2Cor e Forma:WhitePeso molecular:253.304'-Isobutylacetophenone
CAS:Produto Controlado<p>Impurity Ibuprofen EP Impurity E<br>Applications 4'-Isobutylacetophenone (Ibuprofen EP Impurity E) is a degradation product of Ibuprofen in tablets, which is a known toxin. Ibuprofen (I140000) impuritiy.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Reynolds, D., et al.: Pharm. Technol., 26, 48 (2002), Wasylaschuk, W., et al.: J. Pharm. Sci., 96, 106 (2007),<br></p>Fórmula:C12H16OCor e Forma:Colourless To Light YellowPeso molecular:176.25S-Methyl-d3-thioacetaminophen
CAS:Produto Controlado<p>Applications S-Methyl-d3-thioacetaminophen is deuterium labeled S-Methyl-3-thioacetaminophen (M330610), a metabolite of Acetaminophen (A161220). Acetaminophen is an analgesic and antipyretic agent used as a pain reliever to treat headache, muscle aches, and arthritis (1,2,3).<br>References (1) McGill, M. R. and Jaeschke, H. Pharm Res. 30, 2174 (2013)(2) Fairbrother, J.E., et al.: Anal. Profiles Drug Subs., 3, 1 (1974) (3) Hinson, J.A., et al.: Rev. Biochem. Toxicol., 2, 103 (1980)<br></p>Fórmula:C92H3H8NO2SCor e Forma:NeatPeso molecular:200.27rac-4’-Methyl Ketoprofen
CAS:<p>Impurity Ketoprofen EP Impurity D; Ketoprofen USP Related Compound A<br>Applications rac-4’-Methyl Ketoprofen (Ketoprofen EP Impurity D; Ketoprofen USP Related Compound A) is an impurity of Ketoprofen (K200800).<br>References Pietta, P. et al.: J. Chrom., 387, 525 (1987); Ueno, K., et al.: J. Med. Chem., 19, 941 (1976); Liversidge, G.G., Anal. Profiles Drug Subs., 10, 443 (1981);<br></p>Fórmula:C17H16O3Cor e Forma:BeigePeso molecular:268.31rac Ketoprofen-d3
CAS:Produto Controlado<p>Applications rac Ketoprofen-d3 is the labeled analogue of rac Ketoprofen (K200800), an anti-inflammatory; analgesic. rac Ketoprofen-d3 has been used in the preparation of labeled human drug metabolites.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Ueno, K., et al.: J. Med. Chem., 19, 941 (1976); Liversidge, G.G., Anal. Profiles Drug Subs., 10, 443 (1981); Jamali, F., et al.: Clin. Pharmacokinet., 19, 197 (1990); Poraj-Kobielska, M., et. al.: J. Labelled Compd. Rad., 56, 513 (2013)<br></p>Fórmula:C162H3H11O3Cor e Forma:NeatPeso molecular:257.30TEMPO
CAS:Produto Controlado<p>Applications TEMPO is a stable radical prepared through the oxidation of 2,2,6,6-tetramethylpiperidine. TEMPO has a wide range of applications including use as a free radical scavenger, a reagent in organic synthesis and as a structural probe in electron spin resonance spectroscopy. TEMPO can also be used as a mediator in free radical polymerization.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Seaton, T.A. et al.: Brain Res., 777, 110 (1997); Tanielyan, S.K. et al.: Top. Catal., 55, 556 (2012); Wolinska-Grabczyk, A. et al.: Polymer, 46, 2461 (2005); Keoshkerian, B. et al.: Polym. Prep., 35, 675 (1994);<br></p>Fórmula:C9H18NOCor e Forma:NeatPeso molecular:156.25rac-Naproxen
CAS:<p>Applications An anti-inflammatory, analgesic, antipyretic. A non-steroidal anti-inflammatory.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Harrison, I.T., et al.: J. Med. Chem., 13, 203 (1970)<br></p>Fórmula:C14H14O3Cor e Forma:NeatPeso molecular:230.26rac Ketorolac Acyl-β-D-glucuronide (Mixture of Diastereomers)
CAS:Produto Controlado<p>Stability Moisture Sensitive, Light Sensitive<br>Applications A metabolite of Ketorolac.<br>References Mroszczak, E., et al.: Drug Metab. Dispos., 15, 618 (1987), Brocks, D., et al.: Clin. Pharmacokinet., 23, 415 (1992), Vakily, M., et al.: Pharm. Res., 12, 1652 (1995), Gillis, J., et al.: Drugs, 53, 139 (1997),<br></p>Fórmula:C21H21NO9Cor e Forma:NeatPeso molecular:431.39Acetaminophen Acetate (Acetaminophen Impurity)
CAS:<p>Impurity Paracetamol EP Impurity H/ Acetaminophen impurity H<br>Applications Acetaminophen Acetate is an impurity of Acetaminophen (A161220), an analgesic and antipyretic agent used as a pain reliever to treat headache, muscle aches, and arthritis (1,2,3).<br>References (1) McGill, M. R. and Jaeschke, H. Pharm Res. 30, 2174 (2013)(2) Fairbrother, J.E., et al.: Anal. Profiles Drug Subs., 3, 1 (1974) (3) Hinson, J.A., et al.: Rev. Biochem. Toxicol., 2, 103 (1980)<br></p>Fórmula:C10H11NO3Cor e Forma:White To Off-WhitePeso molecular:193.20Phenacetin
CAS:Produto Controlado<p>Applications Analgesic, antipyretic. Component of APC tablets, analgesic mixture also containing aspirin and caffeine. Phenacetin is reasonably anticipated to be a human carcinogen; analgesic mixtures containing Phenacetin are listed as known human carcinogens.<br>References Boyd, et al.: Toxicol. Appl. Pharmacol., 1, 240 (1959), Dubach, C.U., et al.: N. Engl. J. Med., 308, 357 (1983),<br></p>Fórmula:C10H13NO2Cor e Forma:WhitePeso molecular:179.22Phenacetin-d3
CAS:Produto Controlado<p>Applications Phenacetin-d3 is the labeled analogue of Phenacetin (P294580), an analgesic, antipyretic; component of APC tablets, analgesic mixture also containing aspirin and caffeine. Phenacetin is reasonably anticipated to be a human carcinogen; analgesic mixtures containing Phenacetin are listed as known human carcinogens.<br>References Boyd, et al.: Toxicol. Appl. Pharmacol., 1, 240 (1959); Dubach, C.U., et al.: N. Engl. J. Med., 308, 357 (1983)<br></p>Fórmula:C10H10D3NO2Cor e Forma:NeatPeso molecular:182.232-Chloronicotinic Acid
CAS:Produto Controlado<p>Applications 2-Chloronicotinic Acid is used in the preparation of 4-thiazolidinone derivatives and Schiff bases displaying antimicrobial activity.<br>References Patel, N. et al.: Saudi Pharm. J., 18, 129 (2010); Patel, N. et al.: J. Sci. Islam Repub. Iran., 21, 121 (2010);<br></p>Fórmula:C6H4ClNO2Cor e Forma:NeatPeso molecular:157.55rac Ketoprofen PEG 400 Ester
Produto Controlado<p>Applications rac Ketoprofen PEG 400 Ester is an impurity of rac Ketoprofen (K200800) which is anti-inflammatory.<br>References Ueno, K., et al.: J. Med. Chem., 19, 941 (1976); Liversidge, G.G., Anal. Profiles Drug Subs., 10, 443 (1981); Jamali, F., et al.: Clin. Pharmacokinet., 19, 197 (1990)<br></p>Fórmula:C18H18O4Cor e Forma:Colourless To Light YellowPeso molecular:n/a
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