Cetonas e Derivados
As cetonas são compostos orgânicos que contêm um grupo carbonilo (C=O) ligado a dois átomos de carbono, formando uma estrutura onde o grupo carbonilo é flanqueado por grupos alquila ou arila. Na farmacologia, as cetonas são utilizadas na formulação de APIs devido à sua capacidade de melhorar a solubilidade e a estabilidade dos princípios ativos. Algumas cetonas possuem propriedades anti-inflamatórias, analgésicas e antimicrobianas. Os derivados de cetonas incluem compostos nos quais o grupo carbonilo é modificado, como os enóis, que têm aplicações na síntese de fármacos e como intermediários químicos na produção de outros compostos bioativos. Os derivados de cetonas são utilizados no desenvolvimento de novos medicamentos, incluindo aqueles para o tratamento de doenças neurodegenerativas, distúrbios metabólicos e certos tipos de câncer, devido aos seus efeitos específicos sobre enzimas e processos celulares.
Foram encontrados 2393 produtos de "Cetonas e Derivados"
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4′-Chloro-3′-(trifluoromethoxy)acetophenone
CAS:Fórmula:C9H6ClF3O2Cor e Forma:SolidPeso molecular:238.591,1′-(2-Hydroxy-5-methyl-1,3-phenylene)diethanone
CAS:Fórmula:C11H12O3Pureza:95.0%Peso molecular:192.2144-Chloro-3-(trifluoromethyl)acetophenone
CAS:Fórmula:C9H6ClF3OPureza:98%Cor e Forma:SolidPeso molecular:222.59(S)-(+)-Ibuprofen Propylene Glycol Ester
CAS:Produto ControladoFórmula:C16H24O3Cor e Forma:NeatPeso molecular:264.362,2-Dimethoxy-2-phenylacetophenone
CAS:<p>Applications 2,2-Dimethoxy-2-phenylacetophenone (cas# 24650-42-8) is a compound useful in organic synthesis.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br></p>Fórmula:C16H16O3Cor e Forma:White PowderPeso molecular:256.301-(3,4-Dimethylphenyl)ethanol
CAS:Produto Controlado<p>Applications 1-(3,4-Dimethylphenyl)ethanol is an intermediate in the production of Medetomidine (M203250), α2-Adrenergic agonist. Sedative; analgesic.<br>References Kagechika, H., et al.: J. Med. Chem., 32, 1098 (1989), ; Scheinin, M., et al.: Br. J. Clin. Pharmacol., 24, 443 (1987),<br></p>Fórmula:C10H14OCor e Forma:NeatPeso molecular:150.22rac-2’,4’-Dimethyl Ketoprofen
CAS:Produto Controlado<p>Applications rac-2’,4’-Dimethyl Ketoprofen is an impurity of Ketoprofen (K200800), an anti-inflammatory and analgesic agent.<br>References Ueno, K., et al.: J. Med. Chem., 19, 941 (1976); Liversidge, G.G., Anal. Profiles Drug Subs., 10, 443 (1981); Jamali, F., et al.: Clin. Pharmacokinet., 19, 197 (1990)<br></p>Fórmula:C18H18O3Cor e Forma:NeatPeso molecular:282.333-(Cyanomethyl)benzoic Acid
CAS:Produto Controlado<p>Impurity Ketoprofen EP Impurity H<br>Applications 3-(Cyanomethyl)benzoic Acid (Ketoprofen EP Impurity H) is a reagent used in the synthesis of various pharmaceutically important compounds, such as its use in the synthesis of neprilysin inhibitors.<br>References Solomon, S.D., et al.: Lancet., 380 1387 (2012); Dadd, M.R., et al.: Enzyme. Microb. Tehcnol., 29, 20 (2001);<br></p>Fórmula:C9H7NO2Cor e Forma:NeatPeso molecular:161.16R-(-)-Norapomorphine Hydrochloride
CAS:Produto Controlado<p>Applications An Apomorphine derivative as inhibitor of amyloid-β (Aβ) fibril formation and their use in amyloidosis based disease.<br>References Howlett, D., et al.: Biochem. J., 340, 283 (1999), Kuner, P., et al.: J. Biol. Chem., 275, 1673 (2000), Ono, K., et al.: J. Neurosci. Res., 75, 742 (2004),<br></p>Fórmula:C16H15NO2•HClPureza:>90%Cor e Forma:NeatPeso molecular:253.3036463-(6-Methoxy-2-naphthalenyl)-5-methylcyclohexanone (Impurity)
CAS:Fórmula:C18H20O2Cor e Forma:NeatPeso molecular:268.35N-(1,5-Dimethyl-3-oxo-2-phenyl-2,3-dihydro-1H-pyrazol-4-yl)-N-methylnitrous amide
CAS:Produto ControladoFórmula:C12H14N4O2Cor e Forma:NeatPeso molecular:246.27(-)-N-Desmethyl Tramadol
CAS:Produto Controlado<p>Applications An optically active metabolite of Tramadol.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Lintz, V.W., et al.: Arzneim.-Forsch./Drug Res., 31, II, 11, 1932 (1981)<br></p>Fórmula:C15H23NO2Cor e Forma:NeatPeso molecular:249.3516,17-Dehydro Capsaicin
CAS:Produto Controlado<p>Stability Light Sensitive<br>Applications A dehydrogenated metabolite of Capsaicin (C175680).<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Glinsukon, T., et al.: Toxicon, 18, 215 (1980), Obach, R., et al.: Drug Metab. Dispos., 29, 1599 (2001), Reilly, C., et al.: Toxicol. Sci., 73, 170 (2003),<br></p>Fórmula:C18H25NO3Cor e Forma:Off-White To BrownPeso molecular:303.43-Methoxy Acetaminophen-d3
CAS:Produto Controlado<p>Applications 3-Methoxy Acetaminophen-d3 is deuterium labeled 3-Methoxy Acetaminophen (M226050). 3-Methoxy Acetaminophen is a metabolite of Acetaminophen (A161220), an analgesic and antipyretic agent used as a pain reliever to treat headache, muscle aches, and arthritis (1,2,3).<br>References (1) McGill, M. R. and Jaeschke, H. Pharm Res. 30, 2174 (2013)(2) Fairbrother, J.E., et al.: Anal. Profiles Drug Subs., 3, 1 (1974) (3) Hinson, J.A., et al.: Rev. Biochem. Toxicol., 2, 103 (1980)<br></p>Fórmula:C92H3H8NO3Cor e Forma:NeatPeso molecular:184.207Ketoprofen-13CD3 Methyl Ester
CAS:Produto Controlado<p>Applications An intermediate for the synthesis of Labelled Ketoprofen.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Derewenda, Z., et al.: J. Mol. Biol., 227, 818 (1992), Grochulski, P., et al.: J. Biol. Chem., 268, 12843 (1993).<br></p>Fórmula:C1613CH13D3O3Cor e Forma:NeatPeso molecular:272.324'-Isobutyl-2,2-dibromopropiophenone
CAS:Produto Controlado<p>Applications Intermediate in the synthesis of Ibuprofen.<br></p>Fórmula:C13H16Br2OCor e Forma:NeatPeso molecular:348.07Trimebutine EP Impurity E-Nitroso
Produto ControladoFórmula:C21H26N2O6Cor e Forma:NeatPeso molecular:402.4411-(2,5-Dimethylphenyl)ethanol
CAS:Produto Controlado<p>Applications 1-(2,5-Dimethylphenyl)ethanol can be used as a reagent in reactions or as a aroma compound<br>References Zhou, J., et al.: Yuanyi Xuebao., 37, 1621-1628 (2010)<br></p>Fórmula:C10H14OCor e Forma:NeatPeso molecular:150.22Trimebutine-d9 Maleate Salt
CAS:Produto Controlado<p>Applications Trimebutine-d9 Maleate Salt, is the labeled analogue of Trimebutine Maleate Salt (T795605), acting as an opioid receptor agonist. Antispasmodic.<br>References Delvaux, M., et al.: J. Int. Med. Res., 25, 225 (1997), Lavit, M., et al.: Arzneim.-Forsch., 50, 640 (2000),<br></p>Fórmula:C22H20D9NO5·C4H4O4Cor e Forma:NeatPeso molecular:512.6D 13223-d4 (Flupirtine Metabolite)
CAS:Produto Controlado<p>Applications The major active labelled metabolite of Flupirtine in human plasma. A potassium channel opener<br>References Niebch, G., et al.: Arzneim.-Forsch., 42, 1343 (1992), Friedel, H., et al.: Drugs, 45, 548 (1993), Fu, I., et al.: J. Pharm. Biomed. Anal., 18, 347 (1998),<br></p>Fórmula:C14H12D4ClFN4OCor e Forma:NeatPeso molecular:314.78(S)-(+)-Ibuprofen 2-(Benzyloxy)propan-1-yl Ester
Produto Controlado<p>Applications (S)-(+)-Ibuprofen 2-(Benzyloxy)propan-1-yl Ester is an intermediate in the synthesis of (S)-(+)-Ibuprofen Propylene Glycol Ester (I140100), a derivative of (S)-(+)-Ibuprofen (I140010), a nonsteroidal anti-inflammatory drug (NSAID).<br>References Busson, M., et al.: J. Int. Med Res., 14, 53 (1986), Meade, E.A., et al.: J. Biol. Chem., 268, 6610 (1993), Davies, N.M., et al.: Clin. Pharmacokinet., 34, 101 (1998),<br></p>Fórmula:C23H30O3Cor e Forma:NeatPeso molecular:354.4836,6'-Dimethoxy-2,2'-binaphthalene
CAS:Produto Controlado<p>Applications 6,6'-Dimethoxy-2,2'-binaphthalene, can be used for the synthesis of novel classes of non-steroidal substrate mimetics, as inhibitors of human CYP17. It is also an impurity of Nabumetone (N200500), a non-steroidal anti-inflammatory drug, acting as anti-inflammatory agent.<br>References Kumpulainen, H., et al.: J. Med. Chem., 49, 1207 (2006); Pinto-Bazurco, M. A. E., et al.: Bioorg. Med. Chem. Lett., 18, 267 (2008);<br></p>Fórmula:C22H18O2Cor e Forma:NeatPeso molecular:314.38(±)-Carisoprodol-d7 (iso-propyl-d7)
CAS:Produto Controlado<p>Applications (±)-Carisoprodol-d7 (iso-propyl-d7) (CAS# 1218911-01-3) is a useful isotopically labeled research compound. As a deuterated drug analog, this compound can be used for inter-patient variability.<br>References Gant, T., et.al., U.S. Pat. Appl. Publ., 28,(2010);<br></p>Fórmula:C12H17D7N2O4Cor e Forma:NeatPeso molecular:267.38Nabumetone-d3
CAS:Produto Controlado<p>Applications Labelled Nabumetone. Anti-inflammatory. Antibacterial.<br>References Kumpulainen, H., et al.: J. Med. Chem., 49, 1207 (2006),<br></p>Fórmula:C152H3H13O2Cor e Forma:NeatPeso molecular:231.30(+)-N,O-Didesmethyl Tramadol
CAS:Produto Controlado<p>Applications An optically active metabolite of Tramadol.<br>References Garrido, M., et al.: J. Pharmacol. Exp. Ther., 305, 710 (2003), Pedersen, R., et al.: Eur. J. Clin. Pharmacol., 62, 513 (2006),<br></p>Fórmula:C14H21NO2Cor e Forma:NeatPeso molecular:235.324-Morpholineethanol-d4
CAS:Produto Controlado<p>Applications Labelled analogue 4-(2-Hydroxyethyl)morpholine, a morphiline derivative used in the preparation of ester prodrugs of naproxen. 4-(2-Hydroxyethyl)morpholine was also shown to induce repair in rat hepatocyte primary culture/DNA.<br></p>Fórmula:C6H9D4NO2Cor e Forma:NeatPeso molecular:135.205-(6-Methoxy-2-naphthalenyl)-3-methyl-2-cyclohexen-1-one
CAS:Produto ControladoFórmula:C18H18O2Cor e Forma:NeatPeso molecular:266.33Methyl 5-Methoxy-2-methylindole-3-acetate
CAS:Produto Controlado<p>Applications Intermediate in the preparation of Indomethacin<br>References Kalgutkar, A.S., et al.: Bioorg. Med. Chem., 13, 6810 (2005),<br></p>Fórmula:C13H15NO3Cor e Forma:NeatPeso molecular:233.26L-Propoxyphene-d5 HCl (propionyl-d5)
CAS:Produto Controlado<p>Applications L-Propoxyphene-d5 Hydrochloride is the isotope labelled analog and L-isomer of Propoxyphene Hydrochloride (P831500); a controlled substance (opiate) and analgesic (narcotic). The α-DL-and D-diastereoisomers possess marked analgesic activity in contrast to the β-diastereoisomers which are substantially inactive. Oral administration of L-Propoxyphene Hydrochloride enhances the analgesic activity of D-Propoxyphene Hydrochloride.<br>References Goldenthal, E.I., et al.: Toxicol. Appl. Pharmacol., 18, 185 (1971); McEwan, B., et al.: Anal. Profiles Drug Subs., 1, 301 (1972); Murphy, P.J., et al.: J. Pharmacol. Exp. Ther., 199, 415 (1976)<br></p>Fórmula:C22H25D5ClNO2Cor e Forma:NeatPeso molecular:380.963,4-Methylenedioxy Propiophenone
CAS:Produto Controlado<p>Applications Intermediate in the production of Isosafrole and Ethylone.<br>References Katoch-Rouse, R., et al.: J. Med. Chem., 46, 642 (2003), Andrade, E., et al.: Chem. Biodivers., 5, 197 (2008),<br></p>Fórmula:C10H10O3Cor e Forma:NeatPeso molecular:178.18(±)-Ibuprofen-d3, Sodium Salt (α-methyl-d3)
CAS:Produto Controlado<p>Applications (±)-Ibuprofen-d3, Sodium Salt (alpha-methyl-d3) (CAS# 1219805-09-0) is a useful isotopically labeled research compound.<br></p>Fórmula:C13H14D3NaO2Cor e Forma:NeatPeso molecular:231.29Nabumetone Dimer Impurity
CAS:Produto Controlado<p>Impurity Nabumetone Dimer Impurity<br>Applications An impurity in a Nabumetone (N200500) drug substance.<br>References Friedel, H., et al.: Drugs, 35, 504 (1988), Davies, N., et al.: Clin. Pharmacokinet., 33, 403 (1997),<br></p>Fórmula:C27H26O3Cor e Forma:NeatPeso molecular:398.49N-Desethyl 3-Bromo Lidocaine
CAS:Produto Controlado<p>Applications Intermediate in the preparation of hydroxylated Lidocaine metabolites.<br></p>Fórmula:C12H17BrN2OCor e Forma:NeatPeso molecular:285.182-Hydroxy Nabumetone
CAS:Produto ControladoFórmula:C15H18O2Cor e Forma:White To Off-WhitePeso molecular:230.306-Benzoyl-2,3-dihydro-1H-pyrrolizine-1-carboxylic acid, racemic
CAS:<p>6-Benzoyl-2,3-dihydro-1H-pyrrolizine-1-carboxylic acid, racemic is a drug product that is used as an analytical standard in the development of new drugs. It is also used to study the metabolism of drugs. 6BPDC has been shown to inhibit bacterial growth by binding to DNA and RNA, thereby preventing transcription and replication. This metabolite can be synthesized in the laboratory.</p>Fórmula:C15H13NO3Pureza:Min. 95%Peso molecular:255.27 g/mol3-Carboxy-a-methyl-benzeneacetic acid
CAS:<p>3-Carboxy-a-methyl-benzeneacetic acid (3CMA) is an impurity in the synthesis of 3,4-methylenedioxyphenylacetone. It is a preservative that has been analysed as a potential source of contamination in pharmaceutical preparations. 3CMA has been shown to be effective at inhibiting the growth of bacteria, yeast and moulds. The analysis time for 3CMA is typically 8 hours or less. The parameters that are used to analyse 3CMA include the use of acetonitrile, optimal porosity and efficiency. The analytical methods used for 3CMA include chromatographic and chromolith methods.</p>Fórmula:C10H10O4Pureza:Min. 95%Peso molecular:194.18 g/molPelubiprofen
CAS:<p>Pelubiprofen is a non-steroidal anti-inflammatory agent and a COX-2 inhibitor, which effectively reduces PGE(2) production by inhibiting COX activity.</p>Fórmula:C16H18O3Pureza:99.69%Cor e Forma:SolidPeso molecular:258.31Nabumetone dimer
CAS:<p>Nabumetone is a nonsteroidal anti-inflammatory drug that is metabolized by the liver to form a dimer. The major metabolite of nabumetone is the dimer, which has been used as an impurity standard for this drug. Nabumetone has been shown to inhibit prostaglandin synthesis, and its metabolites have been studied for their effects on various enzymes.</p>Fórmula:C27H26O3Pureza:Min. 95%Peso molecular:398.49 g/molN-(4-Hydroxyphenyl)propanamide
CAS:<p>The N-(4-hydroxyphenyl)propionamide (HPPA) is a synthetic drug that binds to the human liver. It has been shown to be effective in preventing implantation of fertilized eggs, and can be used as a diagnostic agent for determining the presence of HPPA in human liver tissue. HPPA is also used as a diluent for other drugs. The HPPA binds to chromatographic components and can be detected using electrochemical detection, which allows it to be used as a targetable probe for cancer research. HPPA is also used to study iontophoretic transport of ions across reconstituted membranes in vitro.</p>Fórmula:C9H11NO2Pureza:(%) Min. 97%Peso molecular:165.19 g/molN-(4-Hydroxyphenyl)acetamide sulfate-d3 sodium
CAS:Produto Controlado<p>Please enquire for more information about N-(4-Hydroxyphenyl)acetamide sulfate-d3 sodium including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>Fórmula:C8H6D3NO5S•NaPureza:Min. 95%Peso molecular:257.24 g/mol(2-Amino-2-(hydroxymethyl)propane-3-ol-1-yl) (5-benzoyl-2,3-dihydro-1H-pyrrolizine-1-carboxylate), racemic
<p>Racemic 2-amino-2-(hydroxymethyl)propane-3-ol-1-yl (5-benzoyl-2,3-dihydro-1H-pyrrolizine-1-carboxylate) is a synthetic drug product. It is used in research and development as an impurity standard. It is also used to synthesize drug products, which are custom synthesis and not commercially available. The racemate is a metabolite of the natural compound "Lysergic acid" and has been studied for its effects on metabolism.</p>Fórmula:C19H22N2O5Pureza:Min. 95%Peso molecular:358.39 g/mol5-Benzoyl-2,3-dihydro-1H-pyrrolizine-1-carboxylic acid - Racemic
CAS:<p>5-Benzoyl-2,3-dihydro-1H-pyrrolizine-1-carboxylic acid - Racemic (5BPC) is a drug that is used for the treatment of pain. It has been shown to be safe and effective in treating postoperative pain when given by intravenous infusion or as an oral tablet. 5BPC has minimal toxicity and is metabolized primarily by the liver with a half life of 2.6 hours. The drug has been found to have pharmacokinetic properties that allow it to be used safely in patients with hepatic impairment and in those recovering from abdominal surgery. 5BPC is a prodrug that undergoes biotransformation by esterases into its active form, pyrrolizidine alkaloid (PA). PA acts as a nonsteroidal anti-inflammatory agent and inhibits prostaglandin synthesis, which leads to analgesia. This drug also has minimal drug interactions because</p>Fórmula:C15H13O3NPureza:Min. 95%Peso molecular:255.27 g/molMavatrep
CAS:<p>Mavatrep (JNJ-39439335) is a selective antagonist of TRPV1 with Ki of 6.5 nM and can be used for studies about inflammatory pain.</p>Fórmula:C25H21F3N2OPureza:98.51% - 99.31%Cor e Forma:SolidPeso molecular:422.44Meperidine Hydrochloride CII
CAS:Produto ControladoAlfentanil (inn), anileridine (inn), bezitramide (inn), bromazepam (inn), difenoxin (inn), diphenoxylate (inn), dipipanone (inn), fentanyl (inn), etc.Fórmula:C15H21NO2·HClCor e Forma:White Crystalline PowderPeso molecular:247.15723Tramadol Related Compound A CIV ((RS,SR)-1-(3-Methoxyphenyl)-2-(dimethylaminomethyl)cyclohexanol hydrochloride)
CAS:Produto ControladoAromatic amino-alcohol-phenols, aromatic amino-acid-phenols and other aromatic amino compounds with oxygen functionFórmula:C16H25NO2·HClCor e Forma:White PowderPeso molecular:263.188533-Chloro-4-hydroxyacetanilide
CAS:<p>3-Chloro-4-hydroxyacetanilide is a chemical compound that belongs to the class of acetanilides. It has long-term toxicity and is used as a drug substance in the production of aniline derivatives. 3-Chloro-4-hydroxyacetanilide has been shown to be carcinogenic in hamsters. The long term exposure to this chemical was shown to cause liver damage and increased incidence of tumours in rats. This drug also contains impurities and traces of chloride, chlorine, and thionyl chloride, which are toxic substances that can cause irritation or burns on contact with skin or eyes.</p>Fórmula:C8H8ClNO2Pureza:Min. 95%Peso molecular:185.61 g/molTramadol Hydrochloride CIV
CAS:Produto ControladoAromatic amino-alcohol-phenols, aromatic amino-acid-phenols and other aromatic amino compounds with oxygen functionFórmula:C16H25NO2·HCICor e Forma:White Crystalline PowderPeso molecular:403.10083JNJ-37822681 dihydrochloride
CAS:<p>JNJ-37822681 dihydrochloride 是特异性的、有中枢活性的，可快速解离的多巴胺 D2受体拮抗剂，与多巴胺 D2L 受体结合的亲和力适中 (Ki=158 nM)。JNJ-37822681 dihydrochloride 在精神分裂症和躁郁症领域有研究价值。</p>Fórmula:C17H19Cl2F5N4Pureza:99.78%Cor e Forma:SolidPeso molecular:445.26Benzoylphenylacetonitrile (3-Benzoylbenzeneacetonitrile)
CAS:Nitrile function compounds, nesoiFórmula:C15H11NOPeso molecular:221.084062,4,5-Trimethylketoprofen ((2RS)-2-[3-(2,4,5-Trimethylbenzoyl)phenyl]propanoic Acid)
CAS:<p>Carboxylic acids with aldehyde or ketone function but without other oxygen function, their anhydrides, halides, peroxides, peroxyacids andtheir deriv</p>Fórmula:C19H20O3Cor e Forma:White Off-White SolidPeso molecular:296.14124Ref: 4Z-M-5323
Produto descontinuadoRef: 4Z-M-6896
Produto descontinuadoRef: 4Z-F-337
Produto descontinuadoRef: 4Z-M-5315
Produto descontinuadoTrinexapac-ethyl
CAS:<p>Trinexapac-ethyl is a useful organic compound for research related to life sciences. The catalog number is T65154 and the CAS number is 95266-40-3.</p>Fórmula:C13H16O5Cor e Forma:SolidPeso molecular:252.27Ref: 4Z-M-5326
Produto descontinuadoMetamizole EP Impurity E
CAS:Fórmula:C12H15N3O4SCor e Forma:White To Off-White SolidPeso molecular:297.33Ref: 4Z-M-538
Produto descontinuadoRef: 4Z-M-105003
Produto descontinuadoRef: 4Z-M-105002
Produto descontinuadoRef: 4Z-M-6810
Produto descontinuadoRef: 4Z-M-6862
Produto descontinuadoRef: 4Z-M-5327
Produto descontinuadoRef: 4Z-M-6897
Produto descontinuadoRef: 4Z-A-0248
Produto descontinuadoRef: 4Z-M-5328
Produto descontinuadoRef: 4Z-A-0244
Produto descontinuado
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