Derivados de Benzimidazol e Imidazol
O benzimidazol é um composto constituído por um anel benzênico fundido a um anel imidazólico, uma estrutura de cinco membros contendo dois átomos de nitrogénio. Os derivados de benzimidazol, como o albendazol, são conhecidos pela sua atividade antiparasitária e antifúngica, sendo utilizados no tratamento de infeções parasitárias e de algumas doenças parasitárias em animais e humanos. O imidazol, por sua vez, é uma estrutura de cinco membros com dois átomos de nitrogénio, presente em diversos compostos biologicamente ativos. Os derivados de imidazol, como o metronidazol, possuem propriedades antimicrobianas e antiparasitárias. Estes compostos também são utilizados na indústria farmacêutica para tratar infeções bacterianas, doenças parasitárias e algumas infeções fúngicas, além de terem aplicações na química orgânica como catalisadores.
Na CymitQuimica, oferecemos benzimidazóis e imidazóis de alta pureza para investigação em química medicinal, farmacologia e biotecnologia.
Foram encontrados 10353 produtos de "Derivados de Benzimidazol e Imidazol"
Ordenar por
Pureza (%)
0
100
|
0
|
50
|
90
|
95
|
100
2-(2,3-Dichlorophenyl)-2-(guanidinoimino) acetonitrile
CAS:<p>Lamotrigine is a chemically unrelated compound, which is the active ingredient of a new class of adjuvant drugs for epilepsy. This drug has been found to be effective against seizures in patients with partial seizures and generalized seizures. Lamotrigine is an orally administered suspensoid that can be mixed with water or other liquids to form a suspension. It has been used as a flavouring agent and an adjuvant in pharmaceuticals, including tablets and capsules. The chemical structure of lamotrigine includes two 2,3-dichlorophenyl groups connected by an amino group (guanidinoimino). This structure gives lamotrigine its chemical name: 2-(2,3-dichlorophenyl)-2-(guanidinoimino) acetonitrile.</p>Fórmula:C9H7Cl2N5Pureza:Min. 95%Peso molecular:256.09 g/mol(4R)-1-(4-O-b-D-Galactopyranosyl-b-D-glucopyranosyl)-4-(2-methylpropyl)-2-pyrrolidinone
CAS:<p>(4R)-1-(4-O-b-D-Galactopyranosyl-b-D-glucopyranosyl)-4-(2-methylpropyl)-2-pyrrolidinone is a synthetic, impurity standard and research and development compound. (4R)-1-(4-O-b-D-Galactopyranosyl-b-D-glucopyranosyl)-4-(2-methylpropyl)-2pyrrolidinone is used as an analytical reference in the synthesis of other compounds. It is also used in drug development for the treatment of tuberculosis. This product has a high purity level and is pharmacopoeia grade.</p>Fórmula:C20H35NO11Pureza:Min. 95%Peso molecular:465.49 g/molScopine-2,2-dithienyl glycolate
CAS:<p>Scopine-2,2-dithienyl glycolate is a catalyst that belongs to the class of dithienyl glycolates. Scopine-2,2-dithienyl glycolate is used in the pharmaceutical industry as an average catalyst for reactions and can be used to recover dimethylbenzene. The method of detection for scopine-2,2-dithienyl glycolate is based on its ability to absorb light at a wavelength of 360 nm. The reaction solution must be monitored carefully during the synthetic process because it has been shown that it can react with water or air and form hydrogen sulfide gas. If this happens, the reaction solution will become cloudy or turbid. This product is a white crystalline solid that appears as tiny needles and has a melting point of 173 degrees Celsius (340 degrees Fahrenheit).</p>Fórmula:C18H19NO4S2Pureza:Min. 95%Peso molecular:377.48 g/molOmeprazole Impurity 65
<p>Impurity 65 is an impurity of Omeprazole, a drug used to treat gastroesophageal reflux disease and peptic ulcer. Impurity 65 is a metabolite of Omeprazole that can be found in the drug product at a concentration up to 0.5%. It has been shown to have anti-inflammatory effects and can be used as a research and development standard for HPLC analysis. Impurity 65 is also used as an impurity standard in the USP pharmacopoeia and other pharmacopoeias around the world.</p>Fórmula:C17H17N3O4Pureza:Min. 95%Peso molecular:327.33 g/molAmino albendazole sulfone
CAS:<p>Amino albendazole sulfone is an anthelmintic drug that is used to treat worm infestations in animals. It is the active metabolite of fenbendazole sulfone and has a terminal half-life of 12 hours in humans. Amino albendazole sulfone can be prepared by chromatographic methods, such as liquid chromatography or gas chromatography, and it can be analyzed with a fluorescence detector. This drug has been shown to have a concentration–time curve following administration to rats and results in an increase in the number of worms eliminated from the body.</p>Fórmula:C10H13N3O2SPureza:Min. 95%Peso molecular:239.3 g/molOxybutynin EP Impurity E
CAS:<p>Oxybutynin EP Impurity E is a research and development impurity standard that is used in the synthesis of Oxybutynin. It can be synthesized by reacting 2-chloro-4-nitroaniline with potassium tert-butoxide, followed by acetylation with acetic anhydride. The purity and structure of this compound have been verified by gas chromatography, mass spectrometry, and melting point analysis. This impurity standard has a CAS number of 1215677-72-7.<br>Oxybutynin EP Impurity E is used as a drug product for the treatment of overactive bladder, urinary incontinence, and painful bladder syndrome/interstitial cystitis. It also helps to reduce pain due to spinal cord injury or multiple sclerosis. <br>The pharmacopoeia name for this compound is 4-(2-Chloroethyl)-1H-imidazoleacetic acid. It has been found to be</p>Fórmula:C23H33NO3Pureza:Min. 95%Peso molecular:371.51 g/molAlbendazole sulfone
CAS:<p>Albendazole sulfone is a metabolite of the drug albendazole. It is used as an analytical standard to measure the concentration of albendazole in human plasma and urine samples. The concentration-time curve for albendazole sulfone can be determined using a nonlinear regression analysis, with the rate constant being calculated from the slope and intercept. This method has been shown to be accurate for predicting pharmacokinetic parameters in humans. Albendazole sulfone is also used as a probe in wastewater treatment studies, where it binds to colloidal gold particles that are used to visualize the removal of small particles by microorganisms.</p>Fórmula:C12H15N3O4SPureza:Min. 95 Area-%Cor e Forma:PowderPeso molecular:297.33 g/mol2-[[(4-Chloro-3-methyl-2-pyridinyl)methyl]sulfinyl]-1H-benzimidazole
CAS:<p>2-[[(4-Chloro-3-methyl-2-pyridinyl)methyl]sulfinyl]-1H-benzimidazole (CAS No. 168167-42-8) is a synthetic compound that is used as an analytical reference standard for HPLC. It is also used in the study of drug metabolism, and it has been shown to induce natural oxidation in vitro. 2-[(4-Chloro-3-methylpyridinium)methylsulfinyl]-1Hbenzimidazole is an impurity found in pharmaceutical products that are synthesized from 1-(2,4,6trichlorophenyl)-3-[(4chloromethyl)phenyl]urea.</p>Fórmula:C14H12ClN3OSPureza:Min. 95 Area-%Cor e Forma:Brown PowderPeso molecular:305.78 g/molDehydrodeoxy donepezil
CAS:<p>Dehydrodeoxy donepezil is an analytical standard that is used in the manufacture of pharmaceuticals. It is a synthetic drug impurity, and its CAS number is 120013-45-8. Dehydrodeoxy donepezil can be found in the API impurity grade of various drugs, including those that are manufactured by Custom synthesis and natural synthesis. The pharmacopoeia states that dehydrodeoxy donepezil has a purity level of 98% or greater. This product can also be found as a metabolite in humans, with its half-life being approximately 40 minutes.</p>Fórmula:C24H29NO2Pureza:Min. 95%Peso molecular:363.49 g/mol1-[[3-Methyl-4-(2,2,2-trifluoroethoxy)-2-pyridinyl]methyl]-2-[[[3-methyl-4-(2,2,2-trifluoroethoxy)-2-pyridinyl]methyl]sulfinyl]-1H-b enzimidazole
CAS:<p>1-[[3-Methyl-4-(2,2,2-trifluoroethoxy)-2-pyridinyl]methyl]-2-[[[3-methyl-4-(2,2,2-trifluoroethoxy)-2-pyridinyl]methyl]sulfinyl]-1H-b enzimidazole is an impurity of a drug product. It is a metabolite that has been shown to be present in human plasma and urine. This compound is synthetically produced and is not found in nature. It has been shown to have niche applications in both analytical chemistry and pharmacopoeia.</p>Fórmula:C25H22F6N4O3SPureza:Min. 95%Peso molecular:572.52 g/molLansoprazole impurity H
CAS:<p>Lansoprazole impurity H is a metabolite of lansoprazole, a proton pump inhibitor that inhibits the production of stomach acid. Lansoprazole impurity H is used in research and development as an analytical standard to measure lansoprazole concentrations in drug products. It is also used as an impurity standard for pharmacopoeia purposes. Lansoprazole impurity H is not known to be toxic, but it has not been evaluated for carcinogenicity or reproductive toxicity.</p>Fórmula:C23H16F3N5OSPureza:90%MinPeso molecular:467.47 g/mol2-Methoxy-5-methyL-N,N-bis(1-methyLethyL)-γ-phenyLbenzenepropanamine fumarate
CAS:<p>2-Methoxy-5-methyL-N,N-bis(1-methyLethyl)-gamma-phenyLbenzenepropanamine fumarate (DMXBPC) is an analgesic that has been shown to be a potent inhibitor of the cytosolic phospholipase A2 and is also cytotoxic. DMXBPC has significant cholinergic activity and can inhibit the synthesis of prostaglandins in the prostate gland. DMXBPC binds to the pyridine ring of DOPA and inhibits its conversion to dopamine. The enantiomers of DMXBPC have different effects on inhibition of phospholipase A2, with the (+) form being more potent than the (-) form. This is due to the fact that (+)DMXBPC binds more tightly to the enzyme than (-)DMXBPC does.</p>Fórmula:C23H33NOPureza:Min. 95%Peso molecular:339.51 g/molcis-(±)-4-[4-[4-[4-[[2-(2,4-Dichlorophenyl)-2-(1H-1,2,4-triazol-1-ylmethyl)-1,3-dioxolan-4-yl]methoxy]phenyl]-1-piperazinyl]phenyl]- 2,4-dihydro-2-propyl-3H-1,2,4-triazol-3-one
CAS:<p>cis-(±)-4-[4-[4-[4-[[2-(2,4-Dichlorophenyl)-2-(1H-1,2,4-triazol-1-ylmethyl)-1,3-dioxolan-4-yl]methoxy]phenyl]-1-piperazinyl]phenyl]- 2,4-dihydro-2-propyl-3H-1,2,4-triazol-3-one is a drug product that is used as a research and development tool. It is an impurity standard for HPLC. This compound has a chemical name of cis-(±)-4-[4-[4-[4-(hydroxymethyl)phenyl]-1piperazinyl]phenyl]-2, 4dihydro 2propyl 3H 1 2 4 triazol 3one. The CAS number for this compound is 7485591 7. This compound</p>Fórmula:C34H36Cl2N8O4Pureza:Min. 95%Peso molecular:691.61 g/mol(R)-1-Phenyl-1,2,3,4-tetrahydroisoquinoline
CAS:<p>(R)-1-Phenyl-1,2,3,4-tetrahydroisoquinoline is a chiral molecule with four stereocenters. It is synthesized by the reaction of sulfamic acid and cyclohexene in the presence of p-toluenesulfonic acid. The product formed is then dehydrogenated to produce (R)-1-phenyl-1,2,3,4-tetrahydroisoquinoline. This compound is soluble in organic solvents such as benzene and ethane and can be used as an acceptor for chiral stationary phases.</p>Fórmula:C15H15NPureza:Min. 95%Cor e Forma:PowderPeso molecular:209.29 g/mol7-Hydroxyhyoscyamine
CAS:<p>7-Hydroxyhyoscyamine is an antibacterial agent that is used in the treatment of bacterial infections. It has been shown to inhibit the growth of a number of bacteria including Staphylococcus aureus, Streptococcus pyogenes, and Escherichia coli. 7-Hydroxyhyoscyamine has been shown to be more potent than 6-hydroxyhyoscyamine (6-OH Hya) for inhibiting protein synthesis in the bacteria. The compound does not have any psychoactive effects, unlike atropine sulfate, which is also an alkaloid found in plants from the Solanaceae family. 7-Hydroxyhyoscyamine can be synthesized by reacting atropine with nitrous acid or hydrochloric acid. This synthetic process leads to n-oxides as impurities, which can be removed by using a reversed phase high performance liquid chromatography (RP HPLC). Validation of this</p>Fórmula:C17H23NO4Pureza:Min. 95%Cor e Forma:PowderPeso molecular:305.4 g/mol1-[[4-(3-Methoxypropoxy)-3-methyl-2-pyridinyl]methyl]-2-[[[4-(3-methoxypropoxy)-3-methyl-2-pyridinyl]methyl]thio]-1H-benzimidazole
CAS:<p>1-[[4-(3-Methoxypropoxy)-3-methyl-2-pyridinyl]methyl]-2-[[[4-(3-methoxypropoxy)-3-methyl-2-pyridinyl]methyl]thio]-1H-benzimidazole is a drug product with analytical applications. It has been shown to have natural and synthetic origins, as well as impurities of its own. It is a custom synthesis and research and development compound that is used for HPLC standardization. The compound has been synthesized for the purpose of drug development and it is intended for niche use.</p>Fórmula:C29H36N4O4SPureza:Min. 95%Peso molecular:536.69 g/molCarbamazepine impurity
CAS:<p>Carbamazepine is a drug that has been used to treat epileptic seizures and trigeminal neuralgia. Impurities in the drug are removed by using chromatographic methods, such as high-performance liquid chromatography (HPLC). The rotarod test is an animal model of motor coordination and balance that can be used to assess the effects of drugs on these functions. Carbamazepine impurities may cause depression and have an epileptic effect on animals. Chronic exposure to carbamazepine can lead to drug reactions and gene polymorphisms, which may alter the metabolism of the drug. Analytical methods for determining carbamazepine impurities include HPLC, gas chromatography mass spectrometry (GC-MS), and thin-layer chromatography (TLC).</p>Fórmula:C15H14N2OPureza:Min. 95%Peso molecular:238.28 g/mol2-(3-(1-Benzylpiperidin-4-yl)-2-oxopropyl)-4,5-dimethoxybenzoic acid
CAS:<p>2-(3-(1-Benzylpiperidin-4-yl)-2-oxopropyl)-4,5-dimethoxybenzoic acid is a synthetic compound that is being researched as a potential drug product. It is an impurity standard for HPLC and has been used in the past to develop drugs. The chemical structure of this compound closely resembles that of the natural metabolite 4,5-dimethoxybenzoic acid, which is found in plants such as thyme. 2-(3-(1-Benzylpiperidin-4-yl)-2-oxopropyl)-4,5-dimethoxybenzoic acid has shown to inhibit human cytochrome P450 enzymes, which may lead to serious side effects when taken orally.</p>Fórmula:C24H29NO5Pureza:Min. 95%Peso molecular:411.49 g/mol3,4-Dimethoxy-2-methylpyridine-N-oxide
CAS:<p>3,4-Dimethoxy-2-methylpyridine-N-oxide is a potent inhibitor of somatostatin, which is known to play a role in the regulation of cancer cell growth and apoptosis. This compound has been shown to inhibit the activity of human kinases, including those involved in tumor cell proliferation. 3,4-Dimethoxy-2-methylpyridine-N-oxide is an anticancer agent that can be used to treat various types of cancer. It has also been found to have inhibitory effects on urine quetiapine and Chinese hamster ovary cells. The compound is a potent analog of kinase inhibitors and can be used as a lead compound for developing new drugs with anticancer properties.</p>Fórmula:C8H11NO3Pureza:Min. 95%Peso molecular:169.18 g/mol1-[[3-Methyl-4-(2,2,2-trifluoroethoxy)-2-pyridinyl]methyl]-2-[[[3-methyl-4-(2,2,2-trifluoroethoxy)-2-pyridinyl]methyl]thio]-1H-benzi midazole
CAS:<p>1-[[3-Methyl-4-(2,2,2-trifluoroethoxy)-2-pyridinyl]methyl]-2-[[[3-methyl-4-(2,2,2-trifluoroethoxy)-2-pyridinyl]methyl]thio]-1H-benzi midazole is a high purity analytical standard that is used to calibrate HPLC. It is found as an impurity in the drug product and as a metabolite. 1-[(3-Methyl-4-(2,2,2 -trifluoroethoxy) - 2 - pyridinyl) methyl] - 2 - [[[3 - methyl (4 ( 2 , 2 , 2 - trifluoroethoxy) - 2 pyridinyl) methyl] thio] - 1 H benzimidazole is the IUPAC name for this compound. This chemical has been synthesized</p>Fórmula:C25H22F6N4O2SPureza:Min. 95%Peso molecular:556.52 g/mol
![2-[[(4-Chloro-3-methyl-2-pyridinyl)methyl]sulfinyl]-1H-benzimidazole](/_next/image/?url=https%3A%2Fstatic.cymitquimica.com%2Fproducts%2F3D%2Fthumb-webp%2FIC21226.webp&w=3840&q=75)
![1-[[3-Methyl-4-(2,2,2-trifluoroethoxy)-2-pyridinyl]methyl]-2-[[[3-methyl-4-(2,2,2-trifluoroethoxy)…](/_next/image/?url=https%3A%2Fstatic.cymitquimica.com%2Fproducts%2F3D%2Fthumb-webp%2FIM25689.webp&w=3840&q=75)
![cis-(±)-4-[4-[4-[4-[[2-(2,4-Dichlorophenyl)-2-(1H-1,2,4-triazol-1-ylmethyl)-1,3-dioxolan-4-yl]meth…](/_next/image/?url=https%3A%2Fstatic.cymitquimica.com%2Fproducts%2F3D%2Fthumb-webp%2FID27219.webp&w=3840&q=75)
![1-[[4-(3-Methoxypropoxy)-3-methyl-2-pyridinyl]methyl]-2-[[[4-(3-methoxypropoxy)-3-methyl-2-pyridin…](/_next/image/?url=https%3A%2Fstatic.cymitquimica.com%2Fproducts%2F3D%2Fthumb-webp%2FIM25351.webp&w=3840&q=75)
![1-[[3-Methyl-4-(2,2,2-trifluoroethoxy)-2-pyridinyl]methyl]-2-[[[3-methyl-4-(2,2,2-trifluoroethoxy)…](/_next/image/?url=https%3A%2Fstatic.cymitquimica.com%2Fproducts%2F3D%2Fthumb-webp%2FIM25690.webp&w=3840&q=75)